Determination of Metal Extraction Process Parameters Using Tracer Technique)

1983 ◽  
Vol 19 (8) ◽  
pp. 257-260 ◽  
Author(s):  
K. Gloe ◽  
P. Mühl
Keyword(s):  
Process Parameters ◽  
Extraction Process ◽  
Metal Extraction ◽  
Tracer Technique

scholarly journals A study on the preparation and quality standard of Saifula granules

2021 ◽  
pp. 1-12
Author(s):  
Maimaiti Aisha ◽  
Atikanmu Wahafu ◽  
Yilifanjiang Kuerban ◽  
Akenmujiang Aierken ◽  
Refuhati Saimaiti ◽  
...  
Keyword(s):  
Process Parameters ◽  
Quality Standard ◽  
Extraction Process ◽  
Scientific Basis ◽  
Orthogonal Test ◽  
Quality Control Standard ◽  
Material Basis ◽  
Good Repeatability ◽  
Total Extraction

Objective: To establish the decocting and formulation technology of Saifula granules, and establish a reliable TLC identification quality control standard. Methods: Orthogonal test was used to optimize the water extraction process and TLC was used for qualitative identification. Results: To optimize the process parameters of SFL granules, first, the content of total flavonoids and the total extraction rate were taken as the indexes. Through single factor and orthogonal test, the optimal extraction process was determined as follows: extraction time 1 h, solvent multiple 1:10, extract three times. After the process parameters were determined, in order to further explain the chemical composition of SFL extract, 15 compounds in SFL extract were identified by UHPLC-Q-Orbitrap-MS, 13 batches of SFL extracts were prepared, and their fingerprints were analyzed. The results showed that there were 28 common characteristic peaks in the 13 batches of SFL extracts. The similarity evaluation results of fingerprints showed that the similarities of 13 batches of SFL extracts were greater than 0.9. An HPLC-DAD method for the simultaneous determination of gallic acid, corilagin, and ellagic acid was established. The method has good repeatability, stability, and accurate results. Conclusion: The standard can comprehensively reflect the material basis of SFL granules, and the above methods are accurate, easy to operate, stable and feasible, and provide scientific basis and basis for the development, promotion, and clinical application of SFL granules.

scholarly journals Quantitative Determination of the Surface Distribution of Supported Metal Nanoparticles: A Laser Ablation–ICP–MS Based Approach

Chemosensors ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 77
Author(s):  
Davide Spanu ◽  
Gilberto Binda ◽  
Marcello Marelli ◽  
Laura Rampazzi ◽  
Sandro Recchia ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
Laser Ablation ◽  
Quantitative Determination ◽  
Metal Nanoparticles ◽  
Total Mass ◽  
Functional Materials ◽  
Metal Extraction ◽  
Ms Analysis ◽  
Icp Ms

A laser ablation–inductively coupled plasma–mass spectrometry (LA–ICP–MS) based method is proposed for the quantitative determination of the spatial distribution of metal nanoparticles (NPs) supported on planar substrates. The surface is sampled using tailored ablation patterns and the data are used to define three-dimensional functions describing the spatial distribution of NPs. The volume integrals of such interpolated surfaces are calibrated to obtain the mass distribution of Ag NPs by correlation with the total mass of metal as determined by metal extraction and ICP–MS analysis. Once this mass calibration is carried out on a sacrificial sample, quantifications can be performed over multiple samples by a simple micro-destructive LA–ICP–MS analysis without requiring the extraction/dissolution of metal NPs. The proposed approach is here tested using a model sample consisting of a low-density polyethylene (LDPE) disk decorated with silver NPs, achieving high spatial resolution over cm2-sized samples and very high sensitivity. The developed method is accordingly a useful analytical tool for applications requiring both the total mass and the spatial distribution of metal NPs to be determined without damaging the sample surface (e.g., composite functional materials and NPs, decorated catalysts or electrodic materials).

Formability of Explosive Welded Mg/Al Bimetallic Bar

2016 ◽  
Vol 716 ◽  
pp. 114-120 ◽  
Author(s):  
Sebastian Mróz ◽  
Piotr Szota ◽  
Teresa Bajor ◽  
Andrzej Stefanik
Keyword(s):  
Plastic Deformation ◽  
Strain Rate ◽  
Process Parameters ◽  
Metal Forming ◽  
Explosive Welding ◽  
Physical Modelling ◽  
Main Process ◽  
Compression Tests ◽  
Welding Method

The paper presents the results of physical modelling of the plastic deformation of the Mg/Al bimetallic specimens using the Gleeble 3800 simulator. The plastic deformation of Mg/Al bimetal specimens characterized by the diameter to thickness ratio equal to 1 was tested in compression tests. The aim of this work was determination of the range of parameters as temperature and strain rate that mainly influence on the plastic deformation of Mg/Al bars during metal forming processes. The tests were carried out for temperature range from 300 to 400°C for different strain rate values. The stock was round 22.5 mm-diameter with an Al layer share of 28% Mg/Al bars that had been produced using the explosive welding method. Based on the analysis of the obtained testing results it has been found that one of the main process parameters influencing the plastic deformation the bimetal components is the initial stock temperature and strain rate values.

scholarly journals Quantitative Determination of Azithromycin in Human Plasma by Liquid Chromatography–Mass Spectrometry and its Application in Pharmackokinetic Study

2012 ◽  
Vol 11 (1) ◽  
pp. 55-63 ◽  
Author(s):  
Maizbha Uddin Ahmed ◽  
Mohammad Safiqul Islam ◽  
Tasmin Ara Sultana ◽  
AGM Mostofa ◽  
Muhammad Shahdaat Bin Sayeed ◽  
...  
Keyword(s):  
Mobile Phase ◽  
Solid Phase ◽  
Internal Standard ◽  
Extraction Process ◽  
Serum Samples ◽  
Limit Of Quantification ◽  
Relative Standard ◽  
Linear Concentration Range ◽  
Linear Concentration

Azithromycin is an effective and well-known antimicrobial agent. In the present study, a simple, sensitive and specific LC/MS/MS method has been developed and validated for the quantification of Azithromycin in  human serum samples using Clarithromycin as internal standard. Azithromycin was extracted from biological matrix  by using solid phase extraction process. The chromatographic separation was performed on Luna C18 (3 ?, 2x150   mm) column with a mobile phase consisting of 35 mM ammonium acetate buffer (mobile phase-A) and acetonitrile  and methanol in ratio of 90:10 ( as mobile phase-B) at a flow rate of 0.25 mL/min. The method was validated over a  linear concentration range of 0.5?50.0 ng/mL and limit of quantification (LOQ) was 0.5 ng/mL with a coefficient of  correlation (r2) = 0.9998. The intra-day and inter-day precision expressed as relative standard deviation were 1.64% – 8.43% and 2.32% – 9.92%, respectively. The average recovery of azithromycin from serum was 98.11%. The method  was successfully applied to a pharmacokinetic study after oral administration of Azithromycin 200 mg/5 ml suspension in healthy Bangladeshi volunteers. DOI: http://dx.doi.org/10.3329/dujps.v11i1.12488 Dhaka Univ. J. Pharm. Sci. 11(1): 55-63, 2012 (June)

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