scholarly journals Bioactive peptides with ACE-I and antioxidant activity produced from milk proteolysis

2017 ◽  
Vol 20 (12) ◽  
pp. 3033-3042 ◽  
Author(s):  
Alaa Mohamed Abd El-Fattah ◽  
Sally Samir Sakr ◽  
Samia Mahmoud El-Dieb ◽  
Hany Abdel Satar Elkashef
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Peptides

scholarly journals A Review of Recent Studies on the Antioxidant Activities of a Third-Millennium Food: Amaranthus spp.

Antioxidants ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. 1236
Author(s):  
Seon-Joo Park ◽  
Anshul Sharma ◽  
Hae-Jeung Lee
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Peptides ◽  
Antioxidant Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Sustainable Food ◽  
Amaranth Species ◽  
Amaranthus Spp

Amaranth (Amaranthus spp.) plant commonly refers to the sustainable food crop for the 21st century. The crop has witnessed significant attention in recent years due to its high nutritional value and agronomic advantages. It is a relatively well-balanced cosmopolitan food that is a protector against chronic diseases. Usually, the antioxidant activities of amaranth are held responsible for its defensive behavior. Antioxidant activity of plants, generally, is attributed to their phytochemical compounds. The current interest, however, lies in hydrolysates and bioactive peptides because of their numerous biological functions, including antioxidant effect. While the importance of bioactive peptides has been progressively recognized, an integrated review of recent studies on the antioxidant ability of amaranth species, especially their hydrolysates and peptides has not been generated. Hence, in this review, we summarize studies focused on the antioxidant capacity of amaranth renewal over the period 2015–2020. It starts with a background and overall image of the amaranth-related published reviews. The current research focusing on in vitro, in vivo, and chemical assays-based antioxidant activity of different amaranth species are addressed. Finally, the last segment includes the latest studies concerning free radical scavenging activity and metal chelation capacity of amaranth protein hydrolysates and bioactive peptides.

Bioactive peptides derived from crimson snapper and in vivo anti-aging effects on fat diet-induced high fat Drosophila melanogaster

2020 ◽  
Vol 11 (1) ◽  
pp. 524-533 ◽  
Author(s):  
Shengyang Chen ◽  
Qian Yang ◽  
Xuan Chen ◽  
Yongqi Tian ◽  
Zhiyu Liu ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Drosophila Melanogaster ◽  
Bioactive Peptides ◽  
Aging Effects ◽  
High Fat

Crimson snapper scale peptides (CSSPs) prepared from crimson snapper scales exhibited significant antioxidant activity in vitro and anti-aging effects in vivo on fat diet-induced high fat Drosophila melanogaster.

scholarly journals Milk-derived bioactive peptides exhibit antioxidant activity through the Keap1-Nrf2 signaling pathway

2020 ◽  
Vol 64 ◽  
pp. 103696 ◽  
Author(s):  
Federica Tonolo ◽  
Alessandra Folda ◽  
Luca Cesaro ◽  
Valeria Scalcon ◽  
Oriano Marin ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Signaling Pathway ◽  
Bioactive Peptides ◽  
Nrf2 Signaling Pathway

scholarly journals FRAKSI PEPTIDA ANTIOKSIDAN DARI KASEIN SUSU KAMBING

2020 ◽  
Vol 31 (2) ◽  
pp. 188-196
Author(s):  
Diana Lestari ◽  
◽  
Joshua Evan ◽  
Maggy Thenawidjaja Suhartono ◽  
◽  
...  
Keyword(s):  
Molecular Weight ◽  
Antioxidant Activity ◽  
Membrane Filtration ◽  
Protein Concentration ◽  
Bioactive Peptides ◽  
Protein Profile ◽  
Positive Control ◽  
Hydrolysis Time ◽  
Hydrolysis Process ◽  
Dpph Method

Milk bioactive peptides are derivative of milk protein produced either through enzymatic activity, digestive processes, or fermentation, that give functional properties. The study aimed to obtain bioactive peptides fraction derived from goat’s milk casein through hydrolysis by papain, analyze the profiles of protein and peptides, and also test the antioxidative activity. The casein isolate was hydrolyzed by papain in a ratio of 100: 0.5 (v/v) at pH 7.0 and 50ºC. Analysis of protein concentration was carried out by the Bradford method and protein profile by SDS-PAGE. Antioxidant assay was carried out by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. A 1,000 ppm ascorbic acid solution was used as positive control. Peptide fractionation was done by membrane filtration with a cut off of 10 kD and 30 kDa. The protein concentration of casein hydrolysates decreased significantly after hydrolysis process with papain. The electrophoresis results showed six protein bands in casein with molecular weight of 7-33 kDa. After the hydrolysis process, all hydrolysates only contained two protein bands with molecular weights of 8 and 5 kDa. The hydrolysis process increased the antioxidant activity of the casein. P0 and P2 hydrolysates had the highest antioxidant activity, and fractions with the highest antioxidant activity were fraction <10 kDa from P0 hydrolysate at 67.89% and 10-30 kDa from P2 hydrolysate at 73.82%. Molecular weight and hydrolysis time affected the antioxidant activity of the hydrolysates. Peptides below 30 kDa have antioxidant activity, whereas those above 30 kDa do not have any antioxidant activity. The antioxidant activity of the peptides decreases upon hydrolysis for more then 2 minutes.

scholarly journals Antioxidant activity of soybean peptides on human hepatic HepG2 cells

2019 ◽  
Vol 7 ◽  
Author(s):  
Lammi Carmen ◽  
Carlotta Bollati ◽  
Anna Arnoldi
Keyword(s):  
Lipid Peroxidation ◽  
Antioxidant Activity ◽  
Hepg2 Cells ◽  
Functional Foods ◽  
Bioactive Peptides ◽  
Oxygen Species ◽  
Cellular Lipid ◽  
Dpph Radical ◽  
Significant Augmentation ◽  
Pre Treatment

Soybean is an interesting source of bioactive peptides useful for the development of functional foods and nutraceuticals. In this study, the antioxidant activity of peptic (P) and tryptic (T) soybean hydrolysates was characterized. Results suggest that both hydrolysates are able to scavenge DPPH radical. Moreover, after induction of oxidative stress by using H2O2, either Soybean P or T pre-treatment reduces the ROS, lipid peroxidation, and NO levels in human hepatic HepG2 cells. HepG2 cells, exposed to H2O2 alone, produce a significant augmentation of intracellular reactive oxygen species (ROS) levels by 29.5%, with the consequence of an augmentation of cellular lipid peroxidation levels up to 112.4±0.5%. The pre-treatment with soybean hydrolysates restores the basal level of ROS and induces a reduction of cellular lipid peroxidation. The antioxidant ability of Soybean P and T are also confirmed by their ability to reduce the H2O2-induced NO levels in HepG2 cells.

scholarly journals Probing the Antioxidant Activity of Functional Proteins and Bioactive Peptides in Hermetia Illucens Larvae Fed with Food Wastes

2021 ◽  
Author(s):  
Jiaxin Lu ◽  
Yuwen Guo ◽  
Atif Muhmood ◽  
Bei Zeng ◽  
Yizhan Qiu ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Ribosomal Protein ◽  
Ribosomal Proteins ◽  
Bioactive Peptides ◽  
Fumarate Hydratase ◽  
Enzymatic Digestion ◽  
Food Wastes ◽  
Histone H2a ◽  
Hermetia Illucens ◽  
Ribosomal Protein S3

Abstract Food waste is becoming more prevalent, and managing it is one of the most important issues in terms of food safety. In this study, functional proteins and bioactive peptides produced from the enzymatic digestion of Black soldier fly (Hermetia illucens L., BSF) fed with food wastes were characterized and quantified using proteomics-based analysis.The results revealed approximately 78 peptides and 57 proteins, including 40S ribosomal protein S4, 60S ribosomal protein L8, ATP synthase subunit alpha, ribosomal protein S3, Histone H2A, NADP- glutamate dehydrogenase, Fumarate hydratase, RNA helicase, Chitin binding Peritrophin-A, Lectin C-type protein, etc. were found in BSF. Furthermore, functional analysis of the proteins revealed that the 60S ribosomal protein L5 (RpL5) in BSF interacted with a variety of ribosomal proteins and played a key role in the glycolytic process (AT14039p). Higher antioxidant activity was found in peptide sequences such as GYGFGGGAGCLSMDTGAHLNR, VVPSANRAMVGIVAGGGRIDKPILK, AGLQFPVGR, GFKDQIQDVFK, and GFKDQIQDVFK. It was concluded that the bioconversion of food wastes by Hermetia illucens broght about the generation of variety of functional proteins and bioactive peptides with strong antioxidant activity. However, more studies are required for exploiting potential of Hermetia illucens in value addition of food wastes.

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