scholarly journals PHYSIOLOGICAL ONTOGENY

1925 ◽  
Vol 42 (3) ◽  
pp. 299-310 ◽  
Author(s):  
Alfred E. Cohn ◽  

In these experiments we have shown that, with the technique adopted, differences in behavior are exhibited by fragments of the heart taken from different localities. The different localities behave in a more or less uniform manner. The pace-making function, for instance, is found at first throughout the cardiac tube but later it is restricted and comes to reside in a special small area at the back of the right auricle near the center. The pace-making system is able to develop a rate comparable to that shown by the whole intact heart, irrespective of the size of the fragment in which it is contained. Later, under the circumstances of the study, the ventricular structures lose the power of spontaneous contraction, and later still, the auricular ones also. It need scarcely be pointed out, however, that this loss refers only to the function of pace making. In its place, the various localities of the heart undoubtedly take on other capabilities. This is what is meant after all by differentiation. The question whether the pace-making and conduction systems reside in the remains of primitive portions of the cardiac tube in an undifferentiated form, or whether on the other hand these primitive portions develop into differentiated structures which preside over these functions may be reviewed afresh. Obviously the tube in its early state possesses these functions; obviously also the major part of the heart loses them during the course of development. A knowledge of the changes in form paralleling changes in function would have great interest. On this phase of the problem we hope to report later. On the basis of these observations, differentiation from the point of view of stimulus production may be viewed perhaps in this manner. Pace making, the conduction of impulses, and contraction are the primitive functions of the tube. As the tube develops into the adult structure, pace making and conduction are supposedly served by tissues resembling in structure the original ones. Whether as a matter of fact a structural change takes place is an interesting and important problem. Those portions of the heart which require to develop greater degrees of energy lose the primitive functions of pace making and conduction, and, in the transformation, take on a differentiated structure. It is, then, not the structures in which the primitive functions of pace making and conduction reside which are differentiated, but the greater mass of ventricular muscle. These reflections have their origin not only from our own work but they grow out of observations to be found in the writings of those (A. Keith and I. Mc-Kenzie) who call the nodal and conduction tissues in the heart, embryonic. But whether from the point of view developed here the use of this term is completely descriptive remains an interesting problem.

2003 ◽  
Vol 34 (3) ◽  
pp. 516-526 ◽  
Author(s):  
Yuji Takano

Since the emergence of Kayne's (1994) stimulating proposal for an antisymmetric theory of phrase structure and linear order, much work has been devoted to arguing for or against his theory as well as discussing its empirical predictions. As a result, for a number of phenomena involving rightward positioning, such as rightward adjuncts, heavy NP shift, extraposition, postverbal subjects, and postverbal constituents in OV languages, there now exist both an approach consistent with Kayne's theory (the antisymmetric approach) and another not consistent with it (the symmetric approach). In such a situation, it is often difficult to show on empirical grounds that one approach is superior to the other (see Rochemont and Culicover 1997). In what follows, I describe this situation with respect to two well-known phenomena in English: rightward positioning of adjuncts and heavy NP shift. For each of these phenomena, the symmetric and antisymmetric approaches have been proposed, and both approaches can correctly account for the data discussed in previous studies. Here, I examine the approaches from a novel point of view, showing that data involving the licensing of negative polarity items allow us to differentiate them and to decide which is the right one for each of the two empirical domains. Interestingly, the relevant facts lead to different conclusions for the two phenomena. The results have important implications for the antisymmetric view of syntax.


2015 ◽  
Vol 2 (3) ◽  
pp. 101-104
Author(s):  
Romana Hricová

Green logistics is very attractive and request the point of view. Many companies try to be “green”, but on the other hand they also must be quick, be in right time in the right place and everything with as low costs as possible. So because of it, they use more road freight transport. Nowadays road freight transport is much expanded as transport companies prefer the possibility to operate just-in-time.  There are several advantages that give road freight transport the first place. Firstly, the truck can be prepared whenever, no matter what time is chosen.  Secondly, the flexibility and no more borders with customs control inside the Schengen Area make freight transport quicker. On the other hand, innovative approaches ask for environmental protection, which becomes one of the most important points of view.  If countries support this environmental friendly transport, this would be reflected in the transport prices which should make rail transport more interesting. Using the methodology in the manuscript was divided to three steps. The first step is to identify relevant questions related to border crossing. Next step is to elaborate a list of border problems, and the last step is an analysis of available data.  


2021 ◽  
pp. 21-156
Author(s):  
Anastasya G. Gacheva ◽  

The chapter analyses Fyodor Dostoevsky’s artistic theology within the context of the tradition of the moral interpretation of dogmas, which developed in Russia during the 19th and the first third of the 20th century. A typical feature of this tradition was the desire to bridge the gap between the temple and the outside of it, between dogmatics and ethics, making the truth of faith the rule of life. The Author shows the development of the idea of the unity of dogmas and commandments in the works of Aleksey Khomiakov, Ivan Kireevsky, Nikolay Fedorov, Vladimir Solov’ev, metropolitan Antony (Khrapovitsky), while simultaneously drawing parallels with Dostoevsky. The work takes into account Dostoevsky’s understanding of two main dogmas of Christianity: the dogma of Trinity and the two-natures dogma. The unconfused and inseparable unity of the Divine hypostases appears in Dostoevsky as an image of perfect interaction between personalities, a rule for social relations, a model of all-encompassing unity of humanity, where the right of personality is reconciled with the right of the whole. Two diary fragments dated 1864 — “Masha is lying on the table…” and “Socialism and Christianity” — are analyzed from the point of view of the Trinitarian question. Dostoevsky holds that when a personality moves towards another and enters in a relation “I” — “you”, considering the other as a face and not as a function, thus giving something to rather than taking something from the other, this personality realizes in his life the mystery of Trinity, professing it in deeds not only in words. Atomicity, antinomy, dualism are corruptions of the Trinitarian principle, while its realization is the idea of “an expanding family, a society-Church, a world that is temple. The Christology of Dostoevsky is analyzed. It is shown that Dostoevsky’s perception of Christ as “the ideal of man in flesh” should be understood not in the context of utopian thought, but as a manifestation of the idea of the deification of man, as expressed in the patristic aphorism: “For the Son of God became man so that we might become God”. The essay shows how the assertion of the equality of Christ’s two natures, Divine and human, affects Dostoevsky’s anthropology and historiosophy. Views of the writer’s contemporaries, as well as of other 20th-Century philosophers and theologians who developed the idea of a moral interpretation of the dogma of Trinity and of the Divine-humanity of Christ (archimandrite Fedor (Bukharev), bishop Ioann (Sokolov), Nikolay Fedorov, Vladimir Solov’ev, archimandrite Antony (Khrapovitsky), Viktor Nesmelov, Sergey Bulgakov, Boris Vysheslavtsev, Nikolay Lossky, Aleksandr Gorsky, Mother Maria (Elizaveta Kuz’mina- Karavaeva)) are considered.


Author(s):  
Dany Amiot ◽  
Edwige Dugas

Word-formation encompasses a wide range of processes, among which we find derivation and compounding, two processes yielding productive patterns which enable the speaker to understand and to coin new lexemes. This article draws a distinction between two types of constituents (suffixes, combining forms, splinters, affixoids, etc.) on the one hand and word-formation processes (derivation, compounding, blending, etc.) on the other hand but also shows that a given constituent can appear in different word-formation processes. First, it describes prototypical derivation and compounding in terms of word-formation processes and of their constituents: Prototypical derivation involves a base lexeme, that is, a free lexical elements belonging to a major part-of-speech category (noun, verb, or adjective) and, very often, an affix (e.g., Fr. laverV ‘to wash’ > lavableA ‘washable’), while prototypical compounding involves two lexemes (e.g., Eng. rainN + fallV > rainfallN). The description of these prototypical phenomena provides a starting point for the description of other types of constituents and word-formation processes. There are indeed at least two phenomena which do not meet this description, namely, combining forms (henceforth CFs) and affixoids, and which therefore pose an interesting challenge to linguistic description, be it synchronic or diachronic. The distinction between combining forms and affixoids is not easy to establish and the definitions are often confusing, but productivity is a good criterion to distinguish them from each other, even if it does not answer all the questions raised by bound forms. In the literature, the notions of CF and affixoid are not unanimously agreed upon, especially that of affixoid. Yet this article stresses that they enable us to highlight, and even conceptualize, the gradual nature of linguistic phenomena, whether from a synchronic or a diachronic point of view.


KPGT_dlutz_1 ◽  
2018 ◽  
Vol 31 (3) ◽  
pp. 585
Author(s):  
Luiz Henrique Urquhart Cademartori ◽  
Noel Antônio Baratieri

As cláusulas pétreas: a possibilidade de revisão constitucional de vinculações de receitas na área da educação Resumo: O artigo aborda os limites e as possibilidades de alteração de normas constitucionais que garantem vinculação orçamentária para funções típicas do Estado tais como a Educação Pública. O problema é saber se uma emenda constitucional supressiva da referida garantia orçamentária seria constitucional ou não. A hipótese que se suscita neste estudo procura delinear em que medida seria inconstitucional tal adoção, posto que estaria restringindo, indiretamente, um direito fundamental, no caso o direito à educação, mas, ao mesmo tempo, esta simples constatação encontraria entraves sob a ótica de uma democracia intergeracional. Considera-se, de uma parte, o direito à educação é protegido, originariamente, no âmbito constitucional brasileiro como cláusula pétrea, mas, de outra, gerações futuras ou problemas conjunturais governamentais posteriores à 1988 podem questionar a legitimidade de normas fundamentais originadas em contexto sociopolítico anterior. Para o desenvolvimento deste trabalho, primeiramente analisam-se as cláusulas pétreas e os limites ao poder reformador. A seguir, estudam-se as referidas cláusulas e a sua evolução constitucional. Posteriormente, faz-se uma análise da constitucionalidade de eventual emenda que suprima a vinculação obrigatória de receitas para a educação sob o prisma da proibição de retrocesso. Palavras chave: Cláusulas pétreas. Constituição. Educação. Retrocesso. Receitas públicas. Safeguard clauses: the possibility of constitutional reviewing the bonded educational income Abstract: The article deals with the limits and possibilities of altering constitutional norms that guarantee budgetary linkage to functions typical of the State as a Public Education. The problem is whether a constitutional amendment suppressing the standard budget guarantee would be constitutional or not. The hypothesis that arises in this study looks for what is necessary, is not a fundamental right, is not a case, but the same, this is a finding found obstacles from the point of view of an intergenerational democracy. It is considered, on the one hand, that the right to education is protected, originally, it is not very Brazilian constitutional as a stony clause, but, on the other hand, future generations or post-1988 governmental conjunctural problems may question the legitimacy of fundamental norms originated in context previous sociopolitical. For the development of this work, firstly they are analyzed like stone clauses and the limits to the reformer power. Next, they are studied as clauses of clauses and their constitutional evolution. Subsequently, an analysis is made of the constitutionality of any amendment that abolishes the mandatory binding of transfer to the critic of a prison of prohibition of retrocession. Keywords: Constitution. Education. Public income. Regression. Safeguard clauses.


2009 ◽  
Vol 6 (1-2) ◽  
pp. 84-101
Author(s):  
Nerijus Čepulis

Šiuo straipsniu siekiama permąstyti tradicinę tapatumo sąvoką. Į tapatumą Vakarų mąstymo istorijoje buvo žiūrima visų pirma ontologiniu požiūriu. Moderniųjų laikų posūkis į subjektą susitelkia į Aš kaip bet kokio tapatumo centrą, pagrindą ir gamintoją. Fenomenologinė analizė tapatumo ištakas pagilina iki Aš santykio su išore, su pasauliu, su kitybe. Tačiau kitybė, tapdama sąmonės turiniu, nėra absoliuti kitybė. Būdas, kuriuo tapatumas, įsisavindamas savinasi pasaulį ir naikina kitybę, yra reprezentacija, siekianti akivaizdumo. Reprezentacija kaip intencionalus įžvalgumas bet kokį objektą lokalizuoja sąmonės šviesoje. Šviesa ir regėjimas – tai paradigminės Vakarų mąstymo tradicijos metaforos. Straipsnyje siekiama parodyti, kodėl ir kaip šviesa bei akivaizdumas netoleruoja absoliučios kitybės. Iš akivaizdumo kerų tapatumas atsitokėti gali tik per atsakingą santykį su Kitu, tai yra etiką. Čia tapatus subjektas praranda pirmumo teisę kito asmens imperatyvo atžvilgiu. Begalybės idėja, draskydama totalų tapatumą iš vidaus, neleidžia jam nurimti ir skatina atsižvelgti į transcendenciją, į kitybę, idant ji būtų laisva nuo prievartinio tapimo egocentrinio tapatumo turiniu ir manipuliacijos auka. Atsakomybė kito žmogaus veido akivaizdoje eina pirma akivaizdaus suvokimo ir įteisina jį.Pagrindiniai žodžiai: tapatumas, akivaizdumas, kitybė, socialumas.Charms of Evident IdentityNerijus Čepulis SummaryIn this article I seek to rethink the traditional notion of identity. In the tradition of Western thought identity was viewed first and foremost from an ontological point of view. After the turn toward the subject, the I is thought of as the centre, the base and the producer of any identity. Phenomenological analysis deepens the origin of identity to the relation of the I to the world, i.e. to the alterity. Yet the alterity, by becoming the content of consciousness, is not an absolute alterity. The way, in which identity assimilates, possesses the world and annihilates alterity, is representation. Representation seeks evidence. Representation as intentional perceptivity localizes every object in the light of consciousness. Light and vision are paradigmatic metaphors of the traditional Western thought. Hence in this article I seek to show why and how light and evidence do not tolerate absolute alterity. Identity can be sobered from the charms of evidence only by responsible relation to the Other, i.e. by ethics. Here identical subject loses the right of priority in front of the imperative of the other person. Idea of infinity worries total identity from within. Infinity does not permit identity to quiet down and induces to heed transcendence and alterity. Only in this way alterity can escape the violence to become a content of egocentrical identity and the victim of manipulation. Responsibility in the face of the other person precedes evident perception and legitimates the latter.Keywords: identity, evidence, alterity, sociality.


2007 ◽  
Vol 56 (6) ◽  
Author(s):  
Marianna Gensabella Furnari

L’impostazione classica della questione bioetica dell’eutanasia attraverso il paradigma dei principi conduce a risolvere la questione con un sì, se si privilegia il principio di autonomia, o con un no se si dà il primato al principio dell’indisponibilità della vita. Il saggio muove dalla proposta che sia possibile un altro approccio, basato sull’interazione, suggerita come linea metodica da Warren T. Reich, del paradigma dei principi con gli altri paradigmi della bioetica: l’esperienza, la cura, la virtù. Il primo momento è ripensare l’eutanasia come l’oggetto di una domanda che viene dalla sofferenza e che, come tale, va accolta ed interpretata in un contesto di relazione. A differenza del suicidio, non vi è qui un darsi la morte, ma un domandare la morte all’altro. L’attenzione etica va spostata dal far centro esclusivamente sull’autonomia al focalizzarsi anche e soprattutto sulla relazione, in particolare sulla complessità e le contraddizioni che segnano oggi la relazione tra il paziente e il medico. Anche se chiede una “cura” limite, paradossale che non può essere data, pena la contraddizione e il ribaltamento degli stessi fini della medicina, la domanda di eutanasia non può restare inevasa, ma deve essere accolta, ri-aperta con l’attenzione che il paradigma di cura impone, con l’humanitas che il paradigma di virtù ci consegna. L’attenzione etica all’esperienza di chi domanda la morte diviene il primo momento per trovare una conciliazione tra momenti apparentemente antitetici, come la sacralità e la qualità della vita, per cogliere la complementarità tra diritti apparentemente antitetici come il diritto ad essere lasciati soli e il diritto a non essere lasciati soli, per sostenere insieme la liberazione dal dolore fisico e la liberazione del dolore dell’anima. Spostando il punto di vista dalla libertà alla relazione, il saggio vuole indicare l’impossibilità etica di dire di sì all’eutanasia proprio sul versante della relazione, ponendo al tempo stesso l’accento non solo sulla responsabilità che il dire di sì comporta, ma anche sulle altre responsabilità di cui la domanda di eutanasia ci fa carico: le responsabilità che riguardano la situazione da cui trae origine, e le altre che riguardano ciò che rimane da fare per rispondere alla richiesta di aiuto e di cura che la domanda sottende. Con il movimento proprio dell’etica della cura, il saggio vuole proporre di non risolvere il dilemma in cui la questione bioetica dell’eutanasia sembra costringerci, rinunciando alla vita o alla libertà, ma di provare a ridefinire il contesto da cui il dilemma ha origine, in modo tale che sia possibile tenere insieme vita e libertà. ---------- Classical approach to the problem of the euthanasia, through the paradigm of the principles conducts to solve the matter with a yes, if the principle of autonomy is privileged, or with a no if the primacy is given to the principle of the unavailability of the life. This paper moves from the proposal that another approach is possible, based on the interaction, suggested as methodic line by Warren T. Reich, of the paradigm of the principles with the other paradigms of the bioethics: the experience, the care, the virtue. The first moment is to consider the euthanasia as the object of a question that comes from the suffering and that, as such, it must be welcomed and interpreted in a context of relationship. Unlike the suicide there is not here a killing oneself, but an asking other for death. The ethical attention must be moved from the exclusive center of autonomy to the relationship, particularly on the complexity and the contradictions that mark the physician-patient relationship between today. Even if it asks a limit “care”, paradoxical that cannot be given, or the aims of the medicine itself would be contradicted and overturned, the question of euthanasia cannot stay outstanding, but must be welcomed, opened again with the attention that the paradigm of care imposes, with the humanitas that the paradigm of virtue delivers us. The ethical attention to the experience of whom asks the death it becomes the first moment to find a conciliation among apparently antithetical moments, as the sacredness and the quality of the life, to gather the complementarity among apparently antithetical rights as the right to be left alone and the right not to be left alone, to sustain together the liberation from the physical pain and the liberation from the pain of the soul. Moving the point of view from freedom to relationship the paper wants to point out the ethical impossibility to say yes to the euthanasia just on the side of the relationship, at the same time setting the accent not only on the responsibility that saying yes means, but also on the other responsibilities of which the question of euthanasia ask us: the responsibilities derived by the situation and the others concerning what to answer to the help request and care that the question subtends. In the way proper of the ethics of the care, the paper proposes not to solve the dilemma of the euthanasia abdicating to the life or to the liberty, but trying to redefine the context from which the dilemma has origin, in such way that it is possible to hold together life and liberty.


PMLA ◽  
1930 ◽  
Vol 45 (2) ◽  
pp. 516-531
Author(s):  
Joseph E. Gillet

The invasion of Italy by Charles VIII in 1494 became, shortly after, the subject of an égloga by Francisco de Madrid, and the peace of Cambray in 1529, which, it was fondly hoped, would end the Franco-Spanish wars in Italy, was celebrated dramatically by Hernán López de Yanguas. The battle of Pavia (Feb. 24, 1525), falling between these two events and marking the culmination of the struggle, is discussed, from the Spanish point of view, naturally, in the present little play which has not thus far been noticed by the students of early Spanish drama. Like the other two it is a festival-play, combining with a political preoccupation the bucolic tone of the dramatic égloga, a type of which the origin may well be the fifth égloga of Juan del Encina “adonde se introducen cuatro pastores, . . . . y primero Beneito entró en la sala adonde el Duque y Duquesa estaban, y comenzó mucho á dolerse y acuitarse porque se sonaba que el Duque, su señor, se habia de partir á la guerra de Francia; . . . . y despues llamaron á Pedruelo, el cual les dió nuevas de paz. . . . .” The play is short, however, and although possibly intended for a performance or actually performed, it is close, both in subject-matter and external appearance, to the news-sheets in ballad-form which were fairly common at the time. The print which is here reproduced formerly belonged to D. Pascual de Gayangos, and is now in the Biblioteca Nacional, in Madrid. It seems to have been mentioned only by Gallardo. On its title-page a vignette represents a battle fought under massive city- or castle-walls by knights in full armour, on foot, some wielding swords, some daggers, several carrying shields, one of which, on the right, is painted with a large human countenance. In the left group of four warriors one has already fallen, pierced by a sword. Behind the right group of three may be distinguished a throng of helmeted figures in a thicket of tall lances.


1959 ◽  
Vol 197 (5) ◽  
pp. 968-970 ◽  
Author(s):  
Frederic Kavaler

A method was devised which made it possible to depolarize ventricular muscle, over a short interval of length, by applying an external voltage and to record, from the same segment, the developed tension. A fiber bundle, 0.5–1.0 mm in diameter, from the right ventricular cavity of the sheep or calf, was inserted into a close-fitting hole in a plastic block, contained in a Tyrode bath. The fibers were depolarized where they exited from the block. The muscle was held, by suction, at two surface points of very small area, 0.4 mm apart. Measurements with microelectrodes showed that the depolarization was roughly uniform over the length of muscle segment from which tension was recorded. By this means, the action potential (normally lasting about 1/2 sec.) could be prolonged to a duration of 2 seconds. This caused tension to be maintained at near-peak levels; relaxation occurred only when the fibers were allowed to repolarize. Evidence was thus adduced in support of the view that the contractile mechanism is continuously responsive to depolarization.


2017 ◽  
Vol 20 (5) ◽  
pp. 1994-2010 ◽  
Author(s):  
Pepita Hesselberth

Taking the “right to disconnect” discussion as a starting point, this article considers how the im/possibility of “opting out” is ruminated in scholarly discourses on technology non-use, media resistance, and media disruption. I argue that while very different in scope, these discourses converge in that they all revolve around a structuring paradox. On one hand, this paradox is set in place by the paradox of dis/connectivity itself (no disconnectivity without connectivity). On the other hand, I argue, it is incited and reinforced by the use of scholarly methods that appear to be at odds with the gesture of disconnectivity itself, whether they be empirical, discursive, or technical (or legislative). This article stakes a claim for the importance looking at these discourses on dis/connectivity from the point of view of this structuring paradox, for it is here, I argue, that the limits of our current “culture of connectivity” are most forcefully negotiated.


Sign in / Sign up

Export Citation Format

Share Document