scholarly journals THE RELATION OF HEART WEIGHT TO THE BASAL METABOLISM AS VARIED BY THYROID ADMINISTRATION

1932 ◽  
Vol 55 (6) ◽  
pp. 903-909 ◽  
Author(s):  
Francis M. Smith ◽  
Eaton M. MacKay

A linear relationship exists in the albino rat between the heart weight and the basal metabolic rate when varied by the administration of active thyroid material. It is suggested that this increase in heart weight which follows the increase in metabolism after thyroid is in the nature of a simple work hypertrophy of the myocardium.

1961 ◽  
Vol 16 (3) ◽  
pp. 397-400 ◽  
Author(s):  
H. E. Lewis ◽  
J. P. Masterton ◽  
S. Rosenbaum

The basal metabolism studied in 29 young adults on 349 occasions over 2 years in the Arctic was 37.4 (sd α 3.7) kcal/m-2/hr-1, and well within the normal British standards. The variability showed no relationship to season. On polar expeditions, men's physiologically significant exposure to cold is small because of efficient protection by clothing and shelter. Information is needed about precise differences of microclimate in the polar regions and at home. Field work could more profitably be directed to the cognate problem of costs of various activities in the cold rather than basal metabolic rate. Submitted on April 25, 1960


The Condor ◽  
2006 ◽  
Vol 108 (4) ◽  
pp. 966-970
Author(s):  
Mark Williamson ◽  
Joseph B. Williams ◽  
Erica Nol

Abstract Abstract The Semipalmated Plover (Charadriussemipalmatus), anarctic-nesting migratory shorebird, regularlyencounters low temperatures during the breedingseason. We measured the basal metabolism of adultsduring incubation at Churchill, Manitoba, Canada todetermine basal metabolic rate (BMR),lower critical temperature(Tlc), total evaporative waterloss (TEWL), and dry thermal conductance(Cm). BMR and Tlcwere 47.4 kJ day−1and 23.3°C, respectively, TEWL was2.5 mL H2O−d,and Cm was1.13 mW g−1 °C−1.Measured BMR and Tlc were consistentwith high values found for other shorebird speciesbreeding in the Arctic, while Cm was18% higher than predicted from allometricequations. These metabolic data suggest thatSemipalmated Plovers are adapted to balance therequirements of incubation against energetic andthermoregulatory demands in the Arctic, especiallyin harsh early breeding season conditions.


1964 ◽  
Vol 19 (5) ◽  
pp. 949-954 ◽  
Author(s):  
M. B. Gill ◽  
L. G. C. E. Pugh

Respiratory determinations were carried out on eight members of the Himalayan Scientific and Mountaineering Expedition 1960—1961 and three Sherpas during a prolonged stay at 5,800 m (19,000 ft). Ventilation and oxygen uptake were similar in both groups, although the Sherpas were smaller men. The Sherpas had lower alveolar ventilation, higher PaCOCO2 and lower PaOO2 values than the scientists. Among six of the scientists mean basal metabolic rate was 10% above the mean value predicted from sea-level standards. There was no increase in the two others, who did not acclimatize. The mean basal metabolic rate in the three Sherpas was +21%. The findings were not explained by the extra O2 cost of increased breathing, changes in body composition, or exposure to cold, although this may have been a factor in the Sherpas. The results were similar to recent South American data on residents at 4,540 m (14,900 ft). It was concluded that acclimatization to great altitudes in man is associated with increase in basal metabolism, but there is insufficient evidence as to whether this is a response to hypoxia or other environmental factors. basal respiration; acclimatized men; high altitude (5,800 m) Submitted on March 30, 1964


1961 ◽  
Vol 16 (6) ◽  
pp. 982-990 ◽  
Author(s):  
Pietro O. Bramante

Oxygen consumption (Vo2) and spontaneous muscular activity of albino rats, recorded with apparatus previously described and quantitated with a new technique, exhibited highly significant correlations when paired in successive 10-min periods with a 5-min lag of Vo2 ( y) in respect to spontaneous muscular activity ( x). Since fasting and nonfasting male rats of different weights (range: 156—462 g) showed at perfect rest a quite narrow scatter of metabolic rates ( y = yaKgb ± 6% se) and since y was linearly correlated with x (se = 7.1% fasting; 5.5% nonfasting), theoretical Vo2 values could be predicted from y = Kgyb( m + nx) when the appropriate value of b, experimentally found (in this case 0.48), was used. In two-thirds of the observations the lowest 5-min values of Vo2 did not represent the true basal metabolic rate of the animal since they coincided with variable amounts of spontaneous activity. Data show that the basal metabolic rate of the albino rat is more predictable than generally admitted. Submitted on May 26, 1961


PEDIATRICS ◽  
1949 ◽  
Vol 4 (6) ◽  
pp. 744-750
Author(s):  
ALBERTA ILIFF ◽  
HARRY H. GORDON ◽  
HELEN MCNAMARA ◽  
W. RANDAL BELL

An analysis of the results of 524 observations of the basal metabolism of 348 obese children is presented. Since only 3% of the basal metabolic rates were lower than minus 15% of the Child Research Council surface area-age standards, it is suggested that these standards can be used satisfactorily in the management of children with obesity. For reasons which are not obvious these standards do not suffice for children with dwarfism.


1960 ◽  
Vol XXXV (III) ◽  
pp. 324-333 ◽  
Author(s):  
Th. Béraud ◽  
A. Vannotti

ABSTRACT A diffuse liver lesion (hepatitis) produced an increase of the organic iodine compounds of the blood without an increase of the basal metabolic rate. By measuring the oxygen consumption of the rat after thyroidectomy and hepatectomy, it was shown that the basal metabolism does not respond any more to the injection of triiodothyronine. Six hours after the radiotriiodothyronine injection, strong retention of hormone in the blood was noticed, a weaker one in the kidney and in the myocardium. This retention is accompanied by a diminution of the urinary elimination. The chromatographic analyses allowed to explain that this was not only due to a slackening of the catabolism with accumulation of triiodothyronine in the circulation and in the tissues, but also to an alteration of the hormonal catabolism. Among the metabolites were found in particular monoiodotyrosine and the glucuronic acid conjugates of triiodothyronine. The kidney compensates the absence of the liver by carrying out the conjugation with glucuronic acid which generally occurs in the liver; the monoiodotyrosine would be the product of a scission, at the periphery, of triiodothyronine. These two processes of degradation explain, at least partly, the absence of a metabolic response after the triiodothyronine injection in the hepatectomized rat.


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