Coefficient of diffusion of tannins in ethanol extracts from Physalis alkekengi L. leaves

This work is aimed at developing a mathematical model equation that can be used to predict the fate of contaminant in the soil environment. The mathematical model was developed based on the fundamental laws of conservation and the equation of continuity given asand was resolved to obtain a quadratic equation of the form C(X) = DX2+vX+f. The developed equation was then used to fit the experimental data that were obtained from the Physio-chemical analysis of the soil samples which were obtained at various depths; within the vicinity of the H & H Asphalt plant Company, located at Enito 3 in Ahoada West L.G.A, River State, Nigeria. The Experimental and Model results obtained from the Calculation and Simulation of the developed models were compared numerically and graphically as presented in this work. It was observed that there is reasonable level of agreement between the three results. The polynomial of the curve was established to ascertain the validity of the model; this was done for all the parameters that were analyzed. From the findings the model developed can be used to predict the concentration of a chemical pollutant at various depths. The reliability of the model developed was established giving the fact that through this quadratic equation the diffusivity (coefficient of diffusion), the water velocity and the irreversible reaction decay rate could be determined.

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TERATOGENIK EKSTRAK ETANOL UWI BANGGAI UNGU (Dioscorea alata L.) PADA MENCIT BETINA (Mus musculus)

Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan ◽

10.36387/jiis.v5i2.511 ◽

2020 ◽

Vol 5 (2) ◽

pp. 309-318

Author(s):

Ihwan Ihwan ◽

◽

Rahmatia Rahmatia ◽

Khildah Khaerati ◽

Keyword(s):

Treatment Group ◽

Embryo Development ◽

Mus Musculus ◽

Birth Defect ◽

Abnormal Development ◽

Dioscorea Alata ◽

Treatment Groups ◽

Study Results ◽

Pregnant Mice ◽

Ethanol Extracts

Teratogenic is an abnormal development on embryo and is the cause of congenital defect or birth defect. This study aims to determine the effect of the addition of Dioscorea alata L. ethanol extracts to the embryo development on pregnant mice whose given orally to 24 mice which divided to 4 treatment groups, they are the normal group (NG) with NaCMC 0.5%; 28 mg/KgBB treatment group; 35 mg/KgBB; 42 mg/Kg BB. The addition of Dioscorea alata L ethanol extracts was done on the sixth day until the 15th day of pregnancy. On the 18th day of pregnancy, Laparaktomi was done to the pregnant mice and the embryo was taken out of the uterus. The observation was done to the fetus numbers, weight weighing of the fetus's body, dan length measurement of the fetus's body. Another observation is the observation of the external organ defect of the embryo. The study results that the addition of Dioscorea alata L ethanol extracts with various doses have no significant effect (P>0.5) to the mice external fetus development. On the examination of the fetus, we can conclude that Dioscorea alata L ethanol extracts don’t give any effect that may cause the defect of the fetus’ external organ.

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