scholarly journals Thermoplastic sago starch nanocomposites wound dressing fortified with antibiotic-modified HNT

2021 ◽  
Vol 1192 (1) ◽  
pp. 012030
Author(s):  
N Abuhamed ◽  
Z Ahmad ◽  
N Sarifuddin
Keyword(s):  
Wound Healing ◽  
Antibacterial Agents ◽  
Bacterial Culture ◽  
Healing Process ◽  
Halloysite Nanotubes ◽  
Sago Starch ◽  
Good Resistance ◽  
Casting Method ◽  
Biocomposite Films ◽  
Solution Casting Method

Abstract Starches were reported to promote wound healing. However, the hydrophilicity of starch help absorbs the exudates from the wounds during the healing process, but it also enables a bacterial infection that slows the healing process. Halloysite nanotubes (HNT) are attracting many biological technologies because of their high loading capacity and biocompatibility. This paper investigates the modified HNT as a carrier for antimicrobials agent in wound healing materials. Halloysite was modified by dispersing it with chloramphenicol solution using a magnetic stirring method. Thermoplastic sago Starch (TPSS)/modified HNT (MHNTs) biocomposite films of different compositions (0.25, 0.5, 0.75 and 1 wt. % HNT) were then developed using the solution casting method. SEM revealed that modified HNT shows good dispersion on the TPSS matrix. With the introduction of modified HNT, the FTIR peaks of TPSS have altered at the peak of 3693.21 cm-1 and 1040.05 cm-1. In addition, modified HNT reduced the water absorption rate of the TPSS films. Furthermore, modified HNT showed good resistance to bacterial culture and significantly reduced the biodegradability rate of TPSS compared to pristine HNT. From the findings, HNT can be a potential carrier for antibacterial agents to withstand bacterial attacks.

Mechanical and morphological properties of modified halloysite nanotube filled ethylene-vinyl acetate copolymer nanocomposites

2018 ◽  
Vol 38 (3) ◽  
pp. 271-279 ◽  
Author(s):  
Suvendu Padhi ◽  
P. Ganga Raju Achary ◽  
Nimai C. Nayak
Keyword(s):  
Vinyl Acetate ◽  
Tensile Modulus ◽  
Ethylene Vinyl Acetate ◽  
Crosslinking Density ◽  
Weight Percent ◽  
Halloysite Nanotubes ◽  
Morphological Properties ◽  
Casting Method ◽  
Solution Casting Method ◽  
Acetate Copolymer

AbstractHalloysite nanotubes (HNTs) were modified by γ-methacryloxypropyltrimethoxysilane (γ-MPS) as it interacts with the aluminol and silanol groups of HNTs present at the edges and surfaces of HNTs. The polymer composites were prepared by means of the solution casting method with ethylene-vinyl acetate (EVA) copolymer having 45% vinyl acetate (VA) content with different weight percent of modified HNTs (m-HNTs). The modification of the HNTs by γ-MPS increases the interfacial and inter-tubular interactions and the degree of dispersion of the HNTs within the EVA matrix which manifest from increase in crosslinking density. The mechanical properties such as tensile strength, tensile modulus and tear strength of nanocomposites were found to increase because of m-HNT. The glass transition temperature (Tg) and the crystalline percentage decreases for EVA/m-HNT nanocomposites were due to the strong interaction between EVA matrix and filler. Also, the EVA/m-HNT nanocomposites exhibited better thermal stability due to the strong inter-tubular interaction.

Preparation and Characterization of Organoclay Reinforced Polylactic Acid Biocomposite Films

2009 ◽  
Vol 67 ◽  
pp. 289-293
Author(s):  
Kunal Das ◽  
Dipa Ray ◽  
N.R. Bandyopadhyay ◽  
Suparna Sengupta ◽  
S.P. Sengupta ◽  
...  
Keyword(s):  
Polylactic Acid ◽  
Moisture Diffusivity ◽  
Elastic Behavior ◽  
Casting Method ◽  
Nano Indentation ◽  
Biocomposite Films ◽  
The Matrix ◽  
Indentation Analysis ◽  
Solution Casting Method

Polylactic acid (PLA) based biocomposite films, reinforced with different loadings of organoclay, were prepared by solution casting method. Four different loadings of clay was done, 2, 5, 10 and 15 weight% with respect to the matrix. These biocomposite films were characterized by mechanical characterization, scanning electron microscopy (SEM) moisture diffusivity property at 93% RH. Both the mechanical and the visco-elastic property of these films were measured by nano indentation technique. Mechanical property by nano indentation analysis revealed an idea about the extent of clay dispersion in the matrix. The amount of clay loading and its dispersion significantly affected the mechanical as well as the Visco-elastic behavior of the biocomposite films. The morphology of the films were observed with the help of SEM.

STUDIES ON BIODEGRADATION OF CELLULOSE NANOFIBRIL REINFORCED STARCH/PVA BIOCOMPOSITE FILMS USING AEROBIC COMPOST ENVIRONMENT

2011 ◽  
Vol 10 (04n05) ◽  
pp. 1143-1146
Author(s):  
SONAKSHI MAITI ◽  
DEBARATI MITRA ◽  
DIPA RAY
Keyword(s):  
Cellulose Nanofibrils ◽  
X Ray Diffraction ◽  
Casting Method ◽  
Scanning Calorimetry ◽  
Xrd Study ◽  
Biocomposite Films ◽  
Structures And Properties ◽  
Significant Difference ◽  
Increasing Trend ◽  
Solution Casting Method

Starch/PVA biocomposite films reinforced with cellulose nanofibrils were prepared by solution casting method incorporating glycerol as a plasticizer. These biocomposite films along with unreinforced films were subjected to biodegradation in an aerobic compost pit. The extents of biodegradation of these films were studied in terms of persentage weight loss. The corresponding changes in the structures and properties of these biocomposites were investigated using Scanning Electron Microscopy (SEM), X-Ray Diffraction (XRD) study and Differential Scanning Calorimetry (DSC). The presence of fillers influenced the arrangement of the starch and PVA molecules in the film compared to that in the unreinforced film. A significant difference was observed in the nature of biodegradation of unreinforced and the reinforced films. The glass transition temperature, as observed from DSC, showed a decreasing trend, while the melting temperature showed an increasing trend after biodegradation. SEM micrographs revealed that the starch portions were consumed at a faster rate compared to polyvinyl alcohol, which was confirmed from XRD graphs also.

scholarly journals Tensile Strength and Moisture Resistance Properties of Biocomposite Films Based on Polyvinyl Alcohol (PVA) with Cellulose as Reinforcement from Durian Peel Fibers

2021 ◽  
Vol 302 ◽  
pp. 02001
Author(s):  
Melbi Mahardika ◽  
Mochamad Asrofi ◽  
Devita Amelia ◽  
Edi Syafri ◽  
Sanjay Mavinkere Rangappa ◽  
...  
Keyword(s):  
Tensile Strength ◽  
Polyvinyl Alcohol ◽  
Cellulose Fibers ◽  
Moisture Resistance ◽  
Solution Casting ◽  
Casting Method ◽  
Elongation At Break ◽  
Biocomposite Films ◽  
Solution Casting Method ◽  
Biocomposite Film

Polyvinyl Alcohol (PVA) based biocomposite film with cellulose was successfully fabricated by the solution casting method. The cellulose fibers were obtained by extraction of durian peel using alkalization and bleaching treatments. These treated cellulose fibers were used for the fabrication of PVA-based biocomposites. The durian peel cellulose fibers were varied by 2%, 4%, 6%, and 8% in the PVA matrix. Tensile test and moisture resistance of biocomposites were evaluated. The 6% addition of cellulose fibers in biocomposites increases the tensile strength up to 54% (37 MPa) than pure PVA film (24 MPa). Conversely, it reduces the elongation at break of the biocomposite film. Meanwhile, the moisture resistance properties of the biocomposites increased with the addition of cellulose fibers. The tensile strength and moisture resistance of biocomposites have been increased due to the homogeneous dispersion of the cellulose fibers and PVA matrix. These biocomposites able to reduce the environmental impacts by utilizing residual lignocellulosic biomass.

scholarly journals Latest Advances on Bacterial Cellulose-Based Antibacterial Materials as Wound Dressings

2020 ◽  
Vol 8 ◽  
Author(s):  
Lu Zheng ◽  
Shanshan Li ◽  
Jiwen Luo ◽  
Xiaoying Wang
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Bacterial Cellulose ◽  
Antibacterial Agents ◽  
Healing Process ◽  
Wound Dressings ◽  
Research Progress ◽  
Wound Healing Process ◽  
Self Healing ◽  
Moist Environment

At present, there are various wound dressings that can protect the wound from further injury or isolate the external environment in wound treatment. Whereas, infection and slow self-healing still exist in wound healing process. Therefore, it is urgent to develop an ideal wound dressing with good biocompatibility and strong antibacterial activity to promote wound healing. Bacterial cellulose is a kind of promising biopolymer because it can control wound exudate and provide a moist environment for wound healing. However, the lack of antibacterial activity limits its application. In this paper, the advantages of bacterial cellulose as wound dressings were introduced, and the preparation and research progress of bacterial cellulose-based antibacterial composites in recent years were reviewed, including adding antibiotics, combining with inorganic antibacterial agents or organic antibacterial agents. Finally, the existing problems and future development direction of bacterial cellulose-based antibacterial wound dressings were discussed.

Pilonidal sinus disease: Karydakis flap procedure in our patients

2020 ◽  
Vol 99 (8) ◽  
Keyword(s):  
Wound Healing ◽  
Pilonidal Sinus ◽  
Healing Process ◽  
Pilonidal Sinus Disease ◽  
Wound Complications ◽  
Limberg Flap ◽  
New Disease ◽  
Sinus Disease ◽  
Flap Procedure

Introduction: Despite the available guidelines, opinions of many surgeons are quite ambiguous when it comes to the therapy of pilonidal sinus disease. The treatment can be a frustrating problem both for the surgeon and the patient because it is associated with wound complications and high recurrence rate. The objective of this study was to analyze the results of patients with pilonidal sinus disease undergoing the Karydakis flap procedure. Methods: A total of 27 patients treated for primary and recurrent pilonidal disease using the Karydakis flap procedure at our department between October 23, 2018 and November 22, 2019 were analyzed prospectively. We evaluated postoperative wound healing, complications and recurrence of the disease in a short-term follow-up period. Disease recurrence was defined as prolonged healing or as a new disease requiring repeated surgery. Results: In December 2019 all 27 patients came for a follow-up visit. The result was a fully lateralized wound without any signs of a new disease in all patients. In May 2020 a follow-up visit by phone was performed. The median follow-up was 12 months. The healing process was free of any serious complications in 25 patients. Seroma formation cases were managed by puncture in the outpatient setting. Conclusion: According to the available evidence and guidelines, off-midline procedures – the Karydakis flap, Bascom cleft lift, and Limberg flap procedures – are associated with lower recurrence rates and better wound healing. An important goal is to achieve complete wound lateralization and to change the configuration of the gluteal cleft by reshaping it, which results in a nicely flattened gluteal crease.

Formulation and Evaluation of Chitosan-Polyaniline Nanocomposites for Controlled Release of Anticancer Drug Doxorubicin

2018 ◽  
Vol 8 (2) ◽  
Author(s):  
Dillip Kumar Behera ◽  
Kampal Mishra ◽  
Padmolochan Nayak
Keyword(s):  
Tensile Strength ◽  
Drug Release ◽  
Nanocomposite Films ◽  
Casting Method ◽  
Sustained Drug Release ◽  
In Vitro Drug Release ◽  
Clay Particles ◽  
Solution Casting Method ◽  
Nanoclay Content

In this present work, chitosan (CS) crosslink with polyaniline (PANI) with montmorilonite (MMT) called as (CSPANI/MMT) and CS crosslink with PANI without MMT called as (CS-PANI) were prepared by employing the solution casting method. Further the formation of nanocomposites CS-PANI/MMT and CS-PANI were investigated using XRD, FTIR, SEM and tensile strength. Water uptake and swelling ratio of the CS-PANI and CS-PANI/MMT were found to decrease with increase in concentration of clay. Mechanical properties of the CS-PANI and CS-PANI/MMT were assessed in terms of tensile strength and extensibility using texture analyzer. Increase in tensile strength and reduction in extensibility was reported with increase in the nanoclay content. In vitro drug release study on CS-PANI and CS-PANI/MMT indicated pronounced sustained release of doxorubicin by the incorporation of clay particles in the CS polymer matrix. Overall CSPANI/MMT nanocomposite films exhibited improved mechanical and sustained drug release properties than CS-PANI.

APPLICATIONS OF CHITOSAN-SULFATHIAZOLE AS ANTIMICROBIAL AGENT

2018 ◽  
Vol 28 (2) ◽  
pp. 429-432
Author(s):  
Dilyana Zvezdova
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Antimicrobial Agent ◽  
Defense Mechanisms ◽  
Solvent Casting ◽  
Casting Method ◽  
Gram Negative ◽  
Positively Charged

Chitosan, a hydrophilic biopolymer industrially obtained by N-deacetylation of chitin, can be applied as an antimicrobial agent. It highlights the applications of chitosan as an antimicrobial agent against fungi, bacteria, and viruses and as an elicitor of plant defense mechanisms. A series of novel chitosan-sulfathiazole nanocomposite (CSFZ) films were prepared by using solvent casting method for wound healing application. Fourier transform infrared spectroscopy (FTIR) was employed to ascertain the interaction between negatively charged sulfathiazole and positively charged chitosan. Moreover, the antibacterial activity of the films was investigated against gram positive and gram negative microorganisms. It was found that all CSFZ films showed good inhibitory activity against all the tested bacteria as compared to control. The above analysis suggested that the CSFZ films could be used as potential candidates for wound healing application.

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