scholarly journals Factors Associated With Treatment and Control of Hypertension in a Healthy Elderly Population Free of Cardiovascular Disease: A Cross-sectional Study

2019 ◽  
Vol 33 (4) ◽  
pp. 350-361 ◽  
Author(s):  
Enayet K Chowdhury ◽  
Mark R Nelson ◽  
Michael E Ernst ◽  
Karen L Margolis ◽  
Lawrence J Beilin ◽  
...  

Abstract BACKGROUND Despite readily available treatments, control of blood pressure (BP) with population aging remains suboptimal. Further, there are gaps in the understanding of the management of high BP in the aged. We explored antihypertensive treatment and control among elderly hypertensive participants free from overt cardiovascular disease (CVD), and identified factors related to both “untreated” and “treated but uncontrolled” high BP. METHODS We analyzed baseline data from 19,114 individuals aged ≥65 years enrolled from Australia and United States (US) in the ASPirin in Reducing Events in the Elderly study. Hypertension was defined as an average systolic/diastolic BP ≥140/90 mm Hg and/or the use of any BP lowering medication. “Controlled hypertension” was defined if participants were receiving antihypertensive medication and BP <140 and 90 mm Hg. Descriptive analyses were used to summarize hypertension control rates; logistic regression was used to investigate relationships with treatment and BP control. RESULTS Overall, 74% (14,213/19,114) of participants were hypertensive; and of these 29% (4,151/14,213) were untreated. Among those treated participants, 53% (5,330/10,062) had BP ≥140/90 mm Hg. Participants who were untreated were more likely to be men, have higher educational status, and be in good physical health, and less likely to have significant comorbidities. The factors related to “treated but uncontrolled” BP included older age, male, Black race (vs. White), using antihypertensive monotherapy (vs. multiple) and residing in Australia (vs. US). CONCLUSIONS High levels of “untreated” and “treated but uncontrolled” BP occur in healthy elderly people without CVD, suggesting there are opportunities for better BP control in the primary prevention of CVD in this population. CLINICAL TRIALS REGISTRATION NCT01038583.

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
E Chowdhury ◽  
M R Nelson ◽  
M E Ernst ◽  
K L Margolis ◽  
L J Beilin ◽  
...  

Abstract Introduction Despite readily available treatments, control of high blood pressure (BP) in the ageing population remains suboptimal. Gaps in understanding the management of high BP amongst the elderly exist, as most studies have been in predominantly middle-aged populations. Purpose We explored pharmacological BP lowering treatment and control among elderly hypertensive participants free from overt cardiovascular disease (CVD), and identified factors related to both “untreated” and “treated but uncontrolled” high BP. Methods We analyzed baseline data from 19,114 individuals aged ≥65 years enrolled from Australia and the US in the ASPirin in Reducing Events in the Elderly (ASPREE) study. Hypertension was defined as an average systolic/diastolic BP ≥140/90 mmHg and/or use of any BP-lowering medication. `Controlled hypertensives” were those receiving BP-lowering medication and with BP <140/90 mmHg. Descriptive analyses were used to summarize hypertension control rates; logistic regression was used to investigate relationships with treatment and BP control. Results Overall, 74% (14,213/19,114) of participants were hypertensive, and of these 29% (4,151/14,213) were untreated. Among those treated, 47% (4,732/10,062) had BP <140/90 mmHg. Participants who were untreated were more likely to be men, have higher educational status, and be in good physical health, and less likely to have significant comorbidities. The factors related to “treated but uncontrolled” hypertension included older age, being men, Black race (versus White), using BP lowering monotherapy and residing in Australia (versus US) (Figure 1). Conclusion(s) There were high levels of “untreated” and “treated but uncontrolled” BP, in an otherwise healthy elderly population, suggesting that opportunities for better BP control exist through targeting intervention to high-risk individuals. Acknowledgement/Funding National Institute on Aging and the National Cancer Institute at NIH; NHMRC Australia, Monash University, Victorian Cancer Agency (Australia)


2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Laura Bordoni ◽  
Joanna J. Samulak ◽  
Angelika K. Sawicka ◽  
Iwona Pelikant-Malecka ◽  
Adrianna Radulska ◽  
...  

Abstract The early atherosclerotic lesions develop by the accumulation of arterial foam cells derived mainly from cholesterol-loaded macrophages. Therefore, cholesterol and cholesteryl ester transfer protein (CETP) have been considered as causative in atherosclerosis. Moreover, recent studies indicate the role of trimethylamine N-oxide (TMAO) in development of cardiovascular disease (CVD). The current study aimed to investigate the association between TMAO and CETP polymorphisms (rs12720922 and rs247616), previously identified as a genetic determinant of circulating CETP, in a population of coronary artery disease (CAD) patients (n = 394) and control subjects (n = 153). We also considered age, sex, trimethylamine (TMA) levels and glomerular filtration rate (GFR) as other factors that can potentially play a role in this complex picture. We found no association of TMAO with genetically determined CETP in a population of CAD patients and control subjects. Moreover, we noticed no differences between CAD patients and control subjects in plasma TMAO levels. On the contrary, lower levels of TMA in CAD patients respect to controls were observed. Our results indicated a significant correlation between GFR and TMAO, but not TMA. The debate whether TMAO can be a harmful, diagnostic or protective marker in CVD needs to be continued.


2019 ◽  
Vol 23 (2) ◽  
Author(s):  
Breno de Sousa Santana ◽  
Bárbara Soares Rodrigues ◽  
Marina Morato Stival ◽  
Cris Renata Grou Volpe

Abstract Objective: to analyze blood pressure control in elderly hypertensives accompanied by a Basic Health Unit of the Federal District, determining the sociodemographic profile and the associated risk factors. Method: this is a cross-sectional study with 133 elderly hypertensive patients. Variables related to sociodemographic factors, life habits, clinical factors and adherence to drug therapy were evaluated through the application of semistructured instruments and validated scales. Results with p <0.05 were considered significant. Results: the elderly presented controlled blood pressure (56.4%) predominantly. The majority of the participants were female and women also had a higher rate of uncontrolled blood pressure (86.2%). Older age was associated with higher blood pressure values (p = 0.031). Alcoholism (p = 0.020) and mean body mass index of 33.0 (p <0.000) were factors associated with hypertension adherence to therapy had more controlled values of systolic and diastolic blood pressure. Conclusion and implications for the practice: it was verified that there is a strong association between the risk factors discussed and the lack of control of the blood pressure of elderly hypertensive, especially with regard to advanced age, alcoholism, obesity and overweight, and it is necessary to reorient the planning and strategies of promotion of health and prevention of diseases directed at the elderly hypertensive in the scope of primary health care.


Author(s):  
Sneha Soni ◽  
Manish Kumar ◽  
Mukesh Shukla

<p class="abstract"><strong>Background:</strong> India is passing through a major demographic and epidemiological transition there by leading to increasing geriatric problems as burning public health issue within the nation. The present cross-sectional study was undertaken to study health consciousness among the elderly in a rural population of Katihar.</p><p class="abstract"><strong>Methods:</strong> The present study was conducted in rural field practice area of Katihar medical college and a total 450 elderly persons were interviewed using pre-designed, pre-tested semi structured questionnaire regarding their health consciousness and health seeking behavior during the study period of one year, from Jan 2013 to Dec 2013. Data was entered in Microsoft excel and analyzed by using frequency and proportion.</p><p class="abstract"><strong>Results:</strong> Majority (69.7%) of the elderly were conscious about health, followed by reluctant group (16.6%), while 13.5% were not conscious about their health. Factors like gender (p=0.00), marital status (p=0.02), social category (p=0.00), educational status (p=0.00), occupation (p=0.00) and financial dependency (p=0.04) were found to be significantly associated with health consciousness among elderly.</p><p class="Default"><strong>Conclusions:</strong> On the basis of these findings, it can be recommended that there is a need not only to develop comprehensive geriatric health-care services, but community based intervention are also needed to increase the overall knowledge and consciousness towards health so as to improve their health seeking behaviour.</p>


1970 ◽  
Vol 16 (1) ◽  
pp. 15-19
Author(s):  
Md Jawadul Haque ◽  
Md Rafiqul Alam

A community based cross-sectional study among the geriatric people i.e. 60 years and aboveage group was carried out in the rural villages of Rangpur district with a view to find out theircommon health problems and the relationship between the health problems and some of theirsocio-economical factors. A total of 1000 geriatric people were interviewed. Among them 73.6%were male and 26.4% were female, majority of them (47.8%) were in the age group 60-64 yearsand about 30% of them were smokers. About 86% of the respondents were suffering from eithera disease or diseases at the time of Interview. The most common diseases suffered by themwere arthritis, diarrhoea, hyperacidity and peptic ulcerative diseases, bronchitis, asthma,hypertension, cataract, dental caries, skin disease, diabetes mellitus, hydrocele, etc.A positive relationship of disease prevalence was found with educational status (p< .001),economical status (p<.01) and dependency states (p< .001) of the respondents. Statisticallysignificant relationship was found between dependency state and mental state of therespondents (p< .001). Good relation with other members of the family was found more inindependent group (p< .001). This study might provide information to formulate effectivepreventive and control measures for health problems of the aged.doi: 10.3329/taj.v16i1.3896TAJ June 2003; Vol.16(1): 15-19


2019 ◽  
Vol 76 (5) ◽  
pp. 580-588 ◽  
Author(s):  
Manije Darooghegi Mofrad ◽  
Nazli Namazi ◽  
Bagher Larijani ◽  
Pamela J. Surkan ◽  
Leila Azadbakht

2018 ◽  
Vol 3 (2) ◽  
pp. 30
Author(s):  
Thairo Fellipe Freitas Oliveira ◽  
Thanieri dos Santos Nascimento ◽  
Samia Jardelle Costa de Freitas Maniva

O envelhecimento populacional ocorre de forma acelerada nos dias atuais. Entre os idosos que vivenciam a perda da funcionalidade destacam-se aqueles que residem em instituição de longa permanência (ILP). O estudo objetiva conhecer a função cognitiva de idosos que vivem em instituição de longa permanência no Sertão Central. Trata-se de um estudo transversal, com abordagem quantitativa. Os dados foram coletados em uma instituição de longa permanência, localizada na zona urbana de Quixeramobim - CE. Participaram do estudo 35 idosos. Para a coleta de dados utilizou-se um instrumento para levantamento de dados sociodemográfico. Além desse instrumento, foi aplicado o Mini-Exame do Estado Mental (MEEM) para avaliação cognitiva. Todos os aspectos éticos foram respeitados, a pesquisa foi aprovada pelo Comitê de Ética e Pesquisa da Unicatólica sob o nº 2.505.547. Entre os participantes, 65,7% são do sexo feminino. A idade média foi de 73 anos (± 7,5 anos), variando de 60 a 92 anos. O score médio total do MEEM foi de 17,3 pontos entre os idosos, referente aos critérios de avaliação o que obteve menor pontuação foi o item de cálculo e atenção, com relação de acerto de 0,68 pontos do total de 5 pontos, o item linguagem de reconhecimento obteve melhor média com 1,9 pontos do total de 2. Os idosos obtiveram 17,3 pontos (escore total médio) no MEEM, abaixo dos 20 pontos proposto pela Sociedade Brasileira de Neurologia (SBN) para analfabetos, visto que este nível de instrução correspondia a 91,4% da amostra, o que nos indica um déficit cognitivo. EVALUATION OF THE COGNITIVE FUNCTION IN ELDERLY PERSONS LIVING IN A LONG-STAY INSTITUTION ABSTRACT Population aging occurs rapidly today. Among the elderly who experience loss of functionality, those who live in a long-term institution (LTI) stand out. This study aims to know the cognitive function of elderly people living in a long-term institution in the Central Hinterland. This is a cross-sectional study with a quantitative approach. Data were collected at a long - term institution, located in the urban area of Quixeramobim - CE. 35 subjects participated in the study. A sociodemographic data collection instrument was used to collect data. In addition to this instrument, the Mini-Exam of the Mental State (MEMS) was applied for cognitive evaluation. All the ethical aspects were respected, the research was approved by the Ethics and Research Committee of the Unicatólica under nº 2,505,547. Among the participants, 65.7% were female. The mean age was 73 years (± 7.5 years), ranging from 60 to 92 years. The mean total score of the MEMS was 17.3 points among the elderly, referring to the evaluation criteria. The lowest score was the item of calculation and attention, with a score of 0.68 points out of the total of 5 points. item recognition language got better average with 1.9 points out of the total of 2. The elderly had 17.3 points (average total score) in the MEMS, below the 20 points proposed by the Brazilian Neurology Society (BNS) for illiterates, since this level of education corresponded to 91.4% of the sample, which indicates cognitive deficit.


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