scholarly journals 491 Clinical Characteristics and Outcomes of Patients Undergoing Emergency Appendicectomy During the Pandemic Of COVID-19 Infection – A Single Centre Experience

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
A Aladeojebi ◽  
H Salgaonkar ◽  
D Murcott ◽  
C Cheruvu
Keyword(s):  
World Health Organisation ◽  
World Health ◽  
Surgical Patient ◽  
Prospective Data ◽  
Patient Demographics ◽  
Presenting Symptoms ◽  
Global Pandemic ◽  
Single Centre Experience ◽  
Patient Selection Criteria ◽  
Novel Coronavirus

Abstract Introduction In March 2020, the World Health Organisation declared a global pandemic with the outbreak of a novel coronavirus. As the morbidity and mortality rates increased, the healthcare system was burdened with grave challenges including decisions on how to manage patients who needed emergency surgery during the pandemic. In the absence of clear guidelines and undetermined effects of peri-operative COVID-19 infection on surgical patient outcomes; our aim was to publish our surgical outcomes for emergency appendicentomies done during the pandemic. Method Prospective data was collated from 1st of March to 5th of June 2020 (n = 132) had appendicectomies over the period stated. Patient demographics, presenting symptoms, peri-operative events, investigations, and post-operative results and complications were documented and analysed. The results were then compared with outcomes of retrospective analysis at the same centre (n = 206) carried out from 1st March to 30th June 2019. Results The incidence of complications of appendicitis were similar without any significant differences. The negative appendix rate was significantly lesser in 2020 group, which may correlate to strict patient selection criteria for surgery. Conclusions Under strict selection protocols to reduce transmission of COVID- 19 and best surgical practice emergency appendicectomy is safe and feasible. However these observations warrant further well-designed future studies.

scholarly journals Novel COVID-19 Global Outbreak and a Need for Proactive Dental Care

2020 ◽  
Author(s):  
Prachi Gupta ◽  
Abhinav Garg ◽  
Lovejeet Ahuja
Keyword(s):  
Health Care Professionals ◽  
Preventive Measures ◽  
Dental Health ◽  
World Health Organisation ◽  
World Health ◽  
Cross Contamination ◽  
Dental Health Care ◽  
Global Pandemic ◽  
Screening Assessment ◽  
Novel Coronavirus

The global pandemic Novel Coronavirus Disease (COVID-19), which originated in Wuhan, has affected the countries worldwide and has been declared as a public health emergency by World Health Organisation. Because of the exclusive features of dental healthcare set-ups, risk of cross-contamination is greater between patients and dental personnel due to high chances of getting in contact with suspected or asymptomatic COVID-19 patients. Preventive measures are essential to be taken for prevention of furthermore spread of nosocomial infection. The present article provides a brief overview on COVID-19 in dental settings and recommended protocols for screening/assessment, patient management and precautions for dental health care professionals.

scholarly journals The potential impact of COVID 19 on poor and conflict-ridden communities in Sub-Sahara Africa (SSA): A conceptual paper

2020 ◽  
Vol 1 (2) ◽  
pp. 125-132
Author(s):  
Mathew Nyashanu ◽  
Tistsi Tsopotsa ◽  
Scovia Nalugo Mbalinda ◽  
Gemma North ◽  
Maureen Mguni ◽  
...  
Keyword(s):  
Policy Development ◽  
World Health Organisation ◽  
World Health ◽  
The Novel ◽  
Public Health Professionals ◽  
Global Pandemic ◽  
Potential Impact ◽  
Wu Zhao ◽  
Future Policy ◽  
Novel Coronavirus

The first cases of the novel coronavirus disease (COVID-19), previously known as 2019-nCoV, were reported in late December 2019 in Wuhan, China (Wu, Zhao, Yu B, et al 2020). The virus then spread to Malaysia and Thailand and eventually to the Americas, Europe, Australia and Africa. On the 11thof March 2020 the World Health Organisation (WHO) declared the COVID-19 a global pandemic. This concept paper  explores the potential impact of COVID-19 on poverty stricken and conflict-ridden communities in Sub-Sahara Africa. In doing so, the paper also explored the implications for public health professionals working with these communities, including recommendation for future policy development.

scholarly journals A potential spice with multifunctional pharmacological properties can prevent COVID-19 disease

2021 ◽  
Vol 9 (6) ◽  
pp. 1840
Author(s):  
Subha Bose Banerjee
Keyword(s):  
Wide Spectrum ◽  
World Health Organisation ◽  
World Health ◽  
Replication Process ◽  
Health Crisis ◽  
Therapeutic Drugs ◽  
Global Pandemic ◽  
Therapeutic Properties ◽  
Novel Coronavirus ◽  
Pharmacologically Active

Novel coronavirus disease (COVID-19) is the major health crisis in the world. World Health Organisation has declared COVID-19 as a global pandemic. There are no effective drugs to treat COVID-19 infection. Till date include remdesivir, umifenovir, favipiravir, lopinavir/ritonavir, ribavirin, hydroxychloroquine, etc. are used to treat this disease. There is an urgent need for public health measures, not only to limit the spread of the virus, but also to implement preventive approaches to control severe COVID-19 disease. Most drugs on the market have shown unwanted symptoms and toxic effects related to these drugs. In this situation people are searching for safe herbal extracts and pharmacologically active molecules having numerous therapeutic properties. Garlic (Allium sativum L.; Family: Amaryllidaceae) is an aromatic herbaceous annual spice with numerous therapeutic properties. Garlic is one of the most efficient natural antibiotics against the wide spectrum of viruses and bacteria. Organosulfur (e.g. allicin and alliin) and flavonoid (e.g. quercetin) compounds are responsible for immunomodulatory effects of this healthy spice. The viral replication process is accelerated with the main structural protease of severe acute respiratory syndrome corona virus-2 (SARS-CoV-2). The formation of hydrogen bonds between this serine-type protease and garlic bioactives in the active site regions inhibits the COVID-19 outbreak. Intake of garlic and its derived-products in regular diet as an adjuvant therapy may minimise side effects and toxicity of the main therapeutic drugs of COVID-19 infection.

scholarly journals A cross-sectional study for determining the perception and preferences of immunity boosters for protection against COVID-19

2020 ◽  
Vol 7 (10) ◽  
pp. 1498
Author(s):  
Dhairya P. Nanavaty ◽  
Ankushi A. Sanghvi ◽  
Manav S. Mehta ◽  
Sarbari Gupta ◽  
Gurusharan Dumra
Keyword(s):  
Family Doctor ◽  
Drug Market ◽  
World Health Organisation ◽  
Cross Sectional Study ◽  
World Health ◽  
The Novel ◽  
Cross Sectional ◽  
Global Pandemic ◽  
Novel Coronavirus ◽  
Source Of Information

Background: The World Health Organisation declared the novel coronavirus (COVID-19) outbreak as a global pandemic on March 11, 2020.  The consumption of vitamins, especially C, D, and zinc, hydroxychloroquine, and Arsenicum album 30 (homeopathy), has increased tremendously. However, the clinical trial showing the benefits of these agents is still underway though there have been a lot of discussion about these in print, electronic, and social media.Method: A questionnaire-based observational study was conducted. The participants were inquired about the use of any type of immunity booster by them and the source of information regarding the same. The data was analysed using Excel and Python.Results: Our study included 1147 participants. A dramatic increase of 21.97% in the consumption of immunity-boosting agents after the COVID-19 outbreak was observed, maximally in Ayurveda. The major source of information for immunity-boosters was provided by friends/family/relatives (50.4%). 52.7% of the respondents selected Ayurveda as their preferred choice of immunity booster (prophylaxis). If the respondents were to develop any of the COVID-19 symptoms, the majority (45.1%) decided to contact their family doctor, and 53.7% chose Allopathy as their preferred system for treatment. 91.5% of the respondents agreed to take a vaccine if it develops.Conclusion: There has been a boom in the immunity booster drug market because people are selecting immunity boosters despite no scientific background. It is imperative to educate people regarding the same and also conduct research studies to find benefits, if any.

scholarly journals Pneumomediastinum in a child with severe COVID-19

2020 ◽  
pp. 20200062
Author(s):  
Anne G Carroll ◽  
Nuala Quinn ◽  
Carl Byrne ◽  
Ghadir Kassab ◽  
Siobhan Whelan ◽  
...  
Keyword(s):  
Health Care Providers ◽  
Clinical Course ◽  
World Health Organisation ◽  
World Health ◽  
The Novel ◽  
Care Providers ◽  
Radiological Findings ◽  
Global Pandemic ◽  
International Data ◽  
Novel Coronavirus

The current global pandemic of the novel coronavirus SARS-CoV2 is a threat to the health and lives of millions of people worldwide. The latest statistics from the World Health Organisation show that there have been 6,515,796 confirmed cases worldwide with 387,298 confirmed deaths (last update 5 June 2020, 10:41 CEST). The majority of critically unwell patients with SARS-CoV2 are adults and the radiological findings associated with them are consistent throughout the literature. However, the reported paediatric cases are few, and as such, there is a limited body of evidence available. More international data is needed, not only on the clinical presentation, but also the radiological findings, so that health-care providers are better able to understand and diagnose this pandemic disease. We describe a case of a previously healthy 9-year-old female who presented to the Emergency Department with symptoms suggestive of raised intracranial pressure. Her CT revealed a medulloblastoma and post-operatively she tested positive for SARS-CoV2. She had a rapid deterioration in her clinical condition and required admission to the intensive care unit (ICU). We provide the supporting radiology along her clinical course in order to demonstrate important insights into this disease in children, including the unusual pnemomediastinum complications which occurred as part of her clinical course. This case is the first reported of its kind.

Jordan’s Public Health and Surveillance Health Policies: During and After COVID-19 (Preprint)

2020 ◽  
Author(s):  
Raeda AlQutob ◽  
Musa Taha Ajlouni ◽  
Mohamed Majed Abu Farraj ◽  
Immanuel Azaad Moonesar
Keyword(s):  
Public Health ◽  
Health System ◽  
Health Financing ◽  
World Health Organisation ◽  
World Health ◽  
The Novel ◽  
Future Health ◽  
Health Crisis ◽  
Global Pandemic ◽  
Novel Coronavirus

UNSTRUCTURED In contemporary times, the wave of the novel Coronavirus disease (COVID-19) classified by the World Health Organisation as global pandemic has unravelled systems and processes including health, economic and social. In the case of the Kingdom of Jordan, the COVID-19 crisis illustrated for the need and ability of the policy making institutions and ministries to take many effective policies, initiatives and procedures that were met with marked approval as the opinion polls conducted by government and private institutions showed. The success of these interventions during the crisis calls upon the country’s health system to take advantage of this experience in the next stage of recovery and resilience to develop, maintain its sustainability, as well as the improvement of a number of hubs to assist the Kingdom in facing the challenges resulting from any future health crisis such as epidemics or natural disasters. The viewpoint interventions that are the most paramount given the current situation as public health evidence must inform activities in seven priority health system areas to manage during and after the pandemic includes factors on: (1) governance and management; (2) service delivery and research; (3) human resources; (4) health information systems; (5) technology and medicine; (6) health financing; and (7) citizens, refugees and communities.

scholarly journals Global Pandemic as a Result of Severe Acute Respiratory Syndrome Coronavirus 2 Outbreak: A Biomedical Perspective

2021 ◽  
Author(s):  
Charles Arvind Sethuraman Vairavan ◽  
Devarani Rameshnathan ◽  
Nagaraja Suryadevara ◽  
Gnanendra Shanmugam
Keyword(s):  
Life Cycle ◽  
Severe Acute Respiratory Syndrome ◽  
Clinical Manifestations ◽  
World Health Organisation ◽  
Laboratory Diagnosis ◽  
Viral Life Cycle ◽  
World Health ◽  
The Public ◽  
Global Pandemic ◽  
Novel Coronavirus

In December 2019, a novel coronavirus had emerged in Wuhan city, China that led to an outbreak resulting in a global pandemic, taking thousands of lives. The infectious virus was later classified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Individuals infected by this novel virus initially exhibit nonspecific symptoms such as dry cough, fever, dizziness and many more bodily complications. From the “public health emergency of international concern” declaration by the World Health Organisation (WHO), several countries have taken steps in controlling the transmission and many researchers share their knowledge on the SARS-COV-2 characteristics and viral life cycle, that may aid in pharmaceutical and biopharmaceutical companies to develop SARS-CoV-2 vaccine and antiviral drugs that interfere with the viral life cycle. In this literature review the origin, classification, aetiology, life cycle, clinical manifestations, laboratory diagnosis and treatment are all reviewed.

scholarly journals 908 Personal Protective Equipment (PPE) Guidance During A Global Pandemic: A Statistical Analysis of National Perceived Confidence, Knowledge, And Educational Deficits Amongst U.K. Based Doctors

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
S Al-Hity ◽  
N Bhamra ◽  
R Kumar ◽  
K Gupta ◽  
J Howard ◽  
...  
Keyword(s):  
Statistical Analysis ◽  
Personal Protective Equipment ◽  
Global Education ◽  
World Health Organisation ◽  
World Health ◽  
Protective Equipment ◽  
Multiple Choice Questions ◽  
Knowledge Based ◽  
Global Pandemic ◽  
Novel Coronavirus

Abstract Introduction March 11th, 2020 saw the World Health Organisation declare a global pandemic following the eruption of the novel coronavirus disease 2019. Unprecedented global demand for personal protective equipment (PPE) was complicated by limited availability and conflicting guidance from healthcare bodies. This study aimed to assess perceived confidence and knowledge of Public Health England’s PPE guidance amongst doctors of varying specialties and grades. Method A nationwide 11-point survey comprising of multiple-choice questions (MCQs) and a Likert scale assessing perceived confidence (1=not confident, 5=very confident) was disseminated to U.K. based doctors using multiple platforms. Results Data collated from 697 respondents revealed average perceived confidence was low. Notably, 59% felt they had received insufficient education regarding up-to-date guidance, with 81% advocating further training. Anaesthetics and ophthalmology were the highest and lowest scoring specialties in knowledge based MCQs, achieving 59% and 31% respectively. Subsequent statistical analysis revealed significant differences between specialties." Conclusions Ensuring consistency in published PPE guidance and education can develop doctor’s confidence and knowledge of appropriate PPE use. The absence of a unified consensus and global education regarding the use of PPE poses significant ramifications for patient and healthcare professional (HCP) safety whilst risking further depletion of already sparse resources.

Comparative docking of SARS-CoV-2 receptors antagonists from repurposing drugs

2020 ◽  
Author(s):  
Micael Davi Lima de Oliveira ◽  
Kelson Mota Teixeira de Oliveira
Keyword(s):  
World Health Organisation ◽  
World Health ◽  
Lung Cells ◽  
The Novel ◽  
High Modulation ◽  
Main Protease ◽  
The World ◽  
Novel Coronavirus ◽  
Viral Receptors ◽  
Theoretical Results

According to the World Health Organisation, until 16 June, 2020, the number of confirmed and notified cases of COVID-19 has already exceeded 7.9 million with approximately 434 thousand deaths worldwide. This research aimed to find repurposing antagonists, that may inhibit the activity of the main protease (Mpro) of the SARS-CoV-2 virus, as well as partially modulate the ACE2 receptors largely found in lung cells, and reduce viral replication by inhibiting Nsp12 RNA polymerase. Docking molecular simulations were performed among a total of 60 structures, most of all, published in the literature against the novel coronavirus. The theoretical results indicated that, in comparative terms, paritaprevir, ivermectin, ledipasvir, and simeprevir, are among the most theoretical promising drugs in remission of symptoms from the disease. Furthermore, also corroborate indinavir to the high modulation in viral receptors. The second group of promising drugs includes remdesivir and azithromycin. The repurposing drugs HCQ and chloroquine were not effective in comparative terms to other drugs, as monotherapies, against SARS-CoV-2 infection.

scholarly journals Riding the waves: the ongoing impact of COVID-19 on a national surgical training cohort

2021 ◽  
Author(s):  
Orla Hennessy ◽  
Amy Lee Fowler ◽  
Conor Hennessy ◽  
David Brinkman ◽  
Aisling Hogan ◽  
...  
Keyword(s):  
Surgical Training ◽  
World Health Organisation ◽  
World Health ◽  
Training Methods ◽  
Viral Spread ◽  
Surgical Services ◽  
Global Pandemic ◽  
Surgical Trainees ◽  
Secondary Survey ◽  
The Impact

Abstract Background The World Health Organisation declared a global pandemic on the 11 March 2020 resulting in implementation of methods to contain viral spread, including curtailment of all elective and non-emergent interventions. Many institutions have experienced changes in rostering practices and redeployment of trainees to non-surgical services. Examinations, study days, courses, and conferences have been cancelled. These changes have the potential to significantly impact the education and training of surgical trainees. Aim To investigate the impact of the COVID-19 pandemic on training, educational, and operative experiences of Irish surgical trainees. Methods Surgical trainees were surveyed anonymously regarding changes in working and educational practices since the declaration of the COVID-19 pandemic on 11 March 2020. The survey was circulated in May 2020 to both core and higher RCSI surgical trainees, when restrictions were at level five. Questions included previous and current access to operative sessions as well as operative cases, previous and current educational activities, access to senior-led training, and access to simulation-/practical-based training methods. A repeat survey was carried out in October 2020 when restrictions were at level two. Results Overall, primary and secondary survey response rates were 29% (n = 98/340) and 19.1% (n = 65/340), respectively. At the time of circulation of the second survey, the number of operative sessions attended and cases performed had significantly improved to numbers experienced pre-pandemic (p < 0.0001). Exposure to formal teaching and education sessions returned to pre-COVID levels (p < 0.0001). Initially, 23% of trainees had an examination cancelled; 53% of these trainees have subsequently sat these examinations. Of note 27.7% had courses cancelled, and 97% of these had not been rescheduled. Conclusion Surgical training and education have been significantly impacted in light of COVID-19. This is likely to continue to fluctuate in line with subsequent waves. Significant efforts have to be made to enable trainees to meet educational and operative targets.

Sign in / Sign up

Export Citation Format

Share Document