scholarly journals The Impact of Supplementation With Whey Protein Isolate and/or Omega-3 Fatty Acids on Sleep and Mood in Postmenopausal Women (SHAPE Study)

2021 ◽  
Vol 5 (Supplement_2) ◽  
pp. 499-499
Author(s):  
Aubree Hawley ◽  
Caroline Baughn ◽  
Angela Tacinelli ◽  
Sam Walker ◽  
Xinya Liang ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Postmenopausal Women ◽  
Whey Protein ◽  
Whey Protein Isolate ◽  
Protein Isolate ◽  
Mood States ◽  
Sleep Disruption ◽  
Omega 3 ◽  
Wrist Actigraphy ◽  
The Impact

Abstract Objectives Approximately 30% of adults ≥ 50 years of age suffer from poor sleep quality and the prevalence of sleep disruption is notably higher in postmenopausal women, with 35 to 60% reporting significant sleep disruption.  Sleep deprivation and low sleep quality are associated with increased energy intake, insulin resistance, elevated glucose, and mood disturbances (e.g., stress, cortisol, and depression). The objective of this study was to determine if the effect of protein and/or omega-3 fatty acid (O3FA) supplementation improves mood and sleep in postmenopausal women. Methods Thirty-nine postmenopausal women (age: 61.3 ± 8.7 years; BMI: 27.6 ± 6.6 kg/m2) were randomly allocated to one of 5 groups: 1) control (CON; no intervention free-living; n = 6), 2) whey protein isolate (PRO; 25 g/d; n = 7), 3) O3FA (DHA/EPA; 4.3 g/d; n = 10), 4) PRO + placebo soybean oil (PRO + PLA; 4.1 g/d; n = 7), or 5) PRO + O3FA (n = 9). Sleep and mood states were assessed at 0, 4, 8, 12, and 16 weeks, except objective sleep, which was assessed at 0, 8, and 16 weeks.  Sleep was measured using the Pittsburgh Sleep quality Index (PSQI) and wrist actigraphy, mood was measured using the Profile of Mood States (POMS), and markers of sleep and mood, orexin, BDNF, and cortisol, were measured using commercially available kits. Results A significant time effect (P < 0.05) was observed on subjective sleep (PSQI), subjective mood states, BDNF, and cortisol concentrations. Although not significant, a greater % decrease in PSQI Global Sleep Score was observed in PRO (-30.3%), O3FA (-23.3%), PRO + PLA (−20.2%), and PRO + O3FA (−26.4%) when compared to an increase in CON (+18%). Similarly, a decrease trend in POMS Total Mood Disturbances from baseline was observed in PRO (−10 ± 27.7), O3FA (−6.7 ± 18.2), and PRO + O3FA (−6.9 ± 27.7) compared to no change in PRO + PLA (0.1 ± 11.5) and an increase in CON (5 ± 15.8). We observed a significant treatment effect on orexin (OXA; pg/mL; P < 0.05). OXA increased significantly in PRO + O3FA compared to all other groups (P < 0.05). Conclusions Although not significant, the data suggests individual and combined supplementation of protein and O3FA have the potential to improve sleep, mood, and orexin levels in postmenopausal women. NCT0303041 Funding Sources Arkansas Biosciences Institute

scholarly journals Protein and Omega-3 Polyunsaturated Fatty Acid Supplementation for 16 Weeks Improves Sleep and Mood States in Postmenopausal Women

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 9-9
Author(s):  
Jamie Baum ◽  
Aubree Hawley ◽  
Caroline Baughn ◽  
Sam Walker ◽  
Angela Tacinelli ◽  
...  
Keyword(s):  
Body Composition ◽  
Sleep Quality ◽  
Postmenopausal Women ◽  
Dietary Intervention ◽  
Sleep Time ◽  
Protein Isolate ◽  
Mood States ◽  
Current Evidence ◽  
Omega 3 ◽  
Wrist Actigraphy

Abstract Objectives Body composition shifts as we age, resulting in loss of skeletal muscle mass with an increase in fat mass, which is linked to disruptions in sleep-wake rhythms and mood disturbance. Current evidence suggests protein and omega-3 polyunsaturated fatty acids (O3FA) individually augment sleep quality and attenuate depression, but a concomitant effect is yet to be determined. The objective of this study was to determine the effect of protein and O3FA supplementation on regulation of sleep and mood states in postmenopausal women. Methods Overweight, postmenopausal women (60.6 ± 9.0 years; BMI: 28.1 ± 6.9) participated in this randomized, controlled, single-blinded, 16 wk dietary intervention. Participants were allocated to 1 of 5 groups: 1) control, no INT (n = 6); 2) whey protein isolate (PRO; 25 g/d; n = 4); 3) O3FA (DHA/EPA; 4.3 g/d; n = 10); 4) PRO + soy bean oil (4.3 g/d) placebo (n = 6), and 5) PRO + O3FA (n = 8). Sleep (via Pittsburgh Sleep Quality Index Global Sleeping Score; PSQI GSS) and total mood disturbances; (TMD; via Profile of Mood States (POMS)) including six affect states of depression, fatigue, anger, tension, confusion, and vigor subscales were assessed at 0, 4, 8, 12, and 16 wks. Sleep was measured at 0, 8, and 16 wk via wrist Actigraphy. Body composition was measured via DXA at 0 and 16 wk. Data were analyzed using two-way ANOVA to assess the relationship between diet, sleep, and mood states over time. Results Overall, all interventions improved PSQI GSS (P < 0.05) by 16 wks. There was a trend for all interventions to improve sleep efficiency (P = 0.06), with no effect on total sleep time. All interventions improved TMD (P < 0.05) and vigor (P < 0.001), with a trend on depression (P = 0.06). PRO, O3FA, and O3FA + PRO significantly improved vigor at 12-wks (P < 0.01). PRO alone significantly improved vigor at 16 wk (P < 0.001) compared to CON. There was no significant effect of intervention on body composition. However, PRO, O3FA, and PRO + O3FA had a positive (564.7 ± 681.4 g) and the CON had a negative (−171.0 ± 991.6) net change of total lean mass at 16 wks. Conclusions This pilot study suggests that PRO, O3FA, and PRO + O3FA have potential to improve sleep and mood in overweight, postmenopausal women. Additional research is needed to determine the long-term individual and concomitant effect of PRO and O3FA on sleep and mood states. NCT0303041. Funding Sources Arkansas Biosciences Institute.

scholarly journals Acute effects of whey protein isolate on blood pressure, vascular function and inflammatory markers in overweight postmenopausal women

2011 ◽  
Vol 105 (10) ◽  
pp. 1512-1519 ◽  
Author(s):  
Sebely Pal ◽  
Vanessa Ellis
Keyword(s):  
Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Postmenopausal Women ◽  
Whey Protein ◽  
Glucose Control ◽  
Vascular Function ◽  
Inflammatory Markers ◽  
Whey Proteins ◽  
Whey Protein Isolate ◽  
Protein Isolate

Previous evidence indicates that chronic consumption of dairy whey proteins has beneficial effects on CVD risk factors. The present study investigated the postprandial effects of whey protein isolate on blood pressure, vascular function and inflammatory markers in overweight and obese postmenopausal women. This was a randomised, three-way cross-over design study where twenty overweight and obese postmenopausal women consumed a breakfast meal in conjunction with one of three supplements: 45 g whey protein isolate, 45 g sodium caseinate or 45 g of a glucose control. Fasting and postprandial blood samples, blood pressure and pulse wave analysis readings were taken for up to 6 h. After consumption of the meal, both systolic and diastolic blood pressure, and augmentation index (AI) decreased initially for all interventions and gradually returned to baseline levels by 6 h. However, there were no significant differences in AI, systolic or diastolic blood pressure within or between the glucose control, casein or whey groups. There were also no significant group effects on plasma inflammatory markers (IL-6, TNF-α and C-reactive protein). The health effects previously seen with chronic whey protein ingestion were not seen in the acute 6 h postprandial period in relation to blood pressure, vascular function or inflammatory markers when compared with casein and a glucose control. This suggests that such effects are better observed from the long-term consumption of whey proteins.

Morphological and physical properties of kefiran-whey protein isolate bionanocomposite films reinforced with Al2O3 nanoparticles

2020 ◽  
Vol 26 (8) ◽  
pp. 666-675
Author(s):  
Zahra Moradi
Keyword(s):  
Mechanical Properties ◽  
Whey Protein ◽  
Water Solubility ◽  
Whey Protein Isolate ◽  
Protein Isolate ◽  
Alumina Nanoparticles ◽  
Vapor Permeability ◽  
Al2o3 Nanoparticles ◽  
Bionanocomposite Films ◽  
The Impact

Considering environmental pollution caused by the non-biodegradable polymers used in food packaging, developing and enhancing the properties of biodegradable films seem to be necessary. For this aim, in the present study, kefiran-whey protein isolate bionanocomposite films were prepared and the impact of different concentrations (1, 3 and 5% w/w) of Al2O3 (alumina) nanoparticles on their physical, morphological, thermal and mechanical properties was studied. Based on the obtained results, an increase in the nanoparticles content led to a significant decrease (p < 0.05) in the water vapor permeability, moisture absorption, moisture content, and water solubility. Scanning electron microscope images showed a homogeneous structure, confirming the good dispersion of alumina nanoparticles with smooth surface up to concentration of 3%. In addition, both thermal stability and mechanical properties of the films were improved by the increased concentrations of alumina. The results of X-ray diffraction indicated that the intensity of the crystalline peaks of film increased with the addition of Al2O3 to kefiran-whey protein isolate matrix. By considering all results, the concentration of 3% was proposed as the appropriate concentration of Al2O3 for the nano-reinforcement of kefiran-whey protein isolate bionanocomposites.

scholarly journals The Effect of Atmospheric Plasma on the Solubility and Dispersibility of Powdered Whey Protein Isolate

2018 ◽  
Author(s):  
Heidi Lightfoot
Keyword(s):  
Plasma Treatment ◽  
Whey Protein ◽  
Functional Properties ◽  
Protein Solubility ◽  
Whey Protein Isolate ◽  
Protein Isolate ◽  
Atmospheric Plasma ◽  
Pristine Sample ◽  
Food And Nutrition ◽  
The Impact

Functional properties of protein macromolecules such as protein solubility are of particular interest to the food and nutrition industries as they have significant implications on other useful properties and characteristics for the development of nutritional and food supplements. Consequently, proteins with specific and consistent functional characteristics are in high demand as essential ingredients in formulated food or in pharmaceutical and industrial mixtures. Proteins need to be highly soluble so that their functional properties can be effectively exploited, therefore methods to improve the solubility of protein powders are currently being developed. It has been hypothesized that atmospheric plasma treatment has an effect on protein solubility and dispersibility. This theory has not been yet explored with whey protein isolate elsewhere; this study is the first to explore the impact of plasma based treatment. The effect of atmospheric plasma treatment on the solubility and dispersibility of dry protein powder has been studied. Each variable was examined using both a pristine sample of whey protein isolate and a sample of whey protein isolate from the same product batch that had been exposed to atmospheric plasma (following ISO 8156 and ISO/TS 17758 protocols). We demonstrate that plasma can successfully increase the solubility and dispersibility of whey protein powder.

Complex coacervation with whey protein isolate and gum arabic for the microencapsulation of omega-3 rich tuna oil

2014 ◽  
Vol 5 (11) ◽  
pp. 2743-2750 ◽  
Author(s):  
Divya Eratte ◽  
Bo Wang ◽  
Kim Dowling ◽  
Colin. J. Barrow ◽  
Benu P. Adhikari
Keyword(s):  
Fatty Acids ◽  
Whey Protein ◽  
Freeze Drying ◽  
Gum Arabic ◽  
Whey Protein Isolate ◽  
Protein Isolate ◽  
Omega 3 Fatty Acids ◽  
Complex Coacervation ◽  
Omega 3 ◽  
Tuna Oil

Tuna oil rich in omega-3 fatty acids was microencapsulated in whey protein isolate (WPI)–gum arabic (GA) complex coacervates, and subsequently dried using spray and freeze drying to produce solid microcapsules.

The influence of flaxseed gum on the microrheological properties and physicochemical stability of whey protein stabilized β-carotene emulsions

2017 ◽  
Vol 8 (1) ◽  
pp. 415-423 ◽  
Author(s):  
Duoxia Xu ◽  
Yameng Qi ◽  
Xu Wang ◽  
Xin Li ◽  
Shaojia Wang ◽  
...  
Keyword(s):  
Whey Protein ◽  
Whey Protein Isolate ◽  
Protein Isolate ◽  
Physicochemical Stability ◽  
The Impact ◽  
Β Carotene ◽  
Flaxseed Gum

The impact of flaxseed gum (FG) on the microrheological properties and physicochemical stability of whey protein isolate (WPI) stabilized β-carotene emulsions at pH 3.0 was studied.

Co-encapsulation and characterisation of omega-3 fatty acids and probiotic bacteria in whey protein isolate–gum Arabic complex coacervates

2015 ◽  
Vol 19 ◽  
pp. 882-892 ◽  
Author(s):  
Divya Eratte ◽  
Stafford McKnight ◽  
Thomas R. Gengenbach ◽  
Kim Dowling ◽  
Colin J. Barrow ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Whey Protein ◽  
Gum Arabic ◽  
Whey Protein Isolate ◽  
Protein Isolate ◽  
Probiotic Bacteria ◽  
Omega 3 Fatty Acids ◽  
Omega 3
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