scholarly journals A Pilot Study on the Impact of Accelerometer Data Reduction Algorithm Selection and the Potential Implications on Behavior Change Recommendations (OR08-03-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Annie Lin ◽  
Dana Larsen ◽  
Ashley Hsu ◽  
Sarah Luna ◽  
Steven Chin ◽  
...  
Keyword(s):  
Behavior Change ◽  
Data Reduction ◽  
Reproductive Age ◽  
Moderate Intensity ◽  
Accelerometer Data ◽  
Women Of Reproductive Age ◽  
Algorithm Selection ◽  
Bivariate Correlation ◽  
Se 33 ◽  
The Impact

Abstract Objectives Physical activity (PA) estimates obtained from recent accelerometer data reduction algorithms have not been compared in women of reproductive-age, a population more likely to engage in unstructured and intermittent PA (such as household cleaning, walking) than men. We investigated whether the accelerometer data from the Crouter, Sasaki and Santos-Lozano algorithms: 1) reported significantly different PA estimates; 2) interacted with weight and age to modify PA estimates; and 3) provided different prevalence of adults meeting PA guidelines. Methods At least four days of accelerometer data were collected from 29 women, ages 18 to 38 years, and processed through three algorithms using an Excel model that automatically removed non-wear data and simultaneously calculated PA estimates [i.e., wear minutes, metabolic equivalent minutes (MET-min)]. A combination of mixed-effects linear regression models and bivariate correlation analyses were used to examine associations between accelerometer data with weight, age, and clinical markers of metabolic status across algorithms. Results The Crouter algorithm estimated significantly more wear minutes in Moderate intensity compared to the Sasaki and Santos-Lozano algorithms [+384 (SE 33) and+356 (SE 33) minutes, respectively]. There were significant interactions between Crouter estimates of Sedentary/Light and Moderate wear minutes with weight and age (all Pinteraction ≤ 0.001, Santos-Lozano algorithm as the reference). Algorithm selection also provided inconsistent findings in the prevalence of adults meeting PA guidelines. Conclusions Recently proposed data reduction algorithms varied in their PA estimates in women of reproductive age. Algorithm selection interacted with weight and age to influence PA estimates and provided inconsistent classification of those who met PA guidelines. Thus, depending on the algorithm selected, behavior change recommendations might differ for each individual due to varying PA estimations. Larger sample sizes are needed to confirm these findings. Funding Sources This research is partially supported by the Cornell University Human Ecology Alumni Association. The first author is currently being supported by the National Institutes of Health.

scholarly journals Sexual Function in Women With and Without Female Genital Mutilation in Reproductive Age in South of Iran

2021 ◽  
Author(s):  
Mahshid Bokaie ◽  
Samaneh Hatefi ◽  
Shahnaz Mojahed ◽  
Nasibeh Roozbeh
Keyword(s):  
Sexual Function ◽  
Female Genital Mutilation ◽  
Reproductive Age ◽  
Public Health Issue ◽  
P Value ◽  
Women Of Reproductive Age ◽  
Genital Mutilation ◽  
Significant Difference ◽  
The Impact ◽  
Female Genital

Abstract Objectives: Female genital mutilation (FGM) is an important public health issue, especially in developing countries and it is still done in some parts of Iran. This study aimed to investigate the effect of FGM on the sexual function of women of reproductive age in Hormozgan province/IRAN.Study design: This study is a descriptive-analytical case-control study that was conducted in 2020 on 209 married women of reproductive age (15-49) in rural areas of Minab and Sirik counties in Hormozgan province/IRAN. Main outcome measures: The reliable and valid questionnaire FSFI for assessing female sexual function in the two groups was used after to obtain informed and voluntary consent from all participants and data with SPSS v: 16 software and with using descriptive/ Analytical statistics tests with a significant level of 0.05 were examined. Results: There is a significant difference between mutilated and non-mutilated women in the total score of sexual function(22.18±3.23 versus 23.41±2.52 respectively, p=0.023) and the domains of lubrication(3.04±0.62 versus 3.3±0.53 respectively, P=0.000), orgasm(3.81±0.63 versus 4.08±0.47 respectively, P=0.003), and sexual satisfaction(5.09±0.1 versus 5.37±0.87 respectively, P=0.017) But in the domains of desire, arousal, and pain in the two groups was no significant difference(P-value>0.05). Conclusion: FGM maybe leads to sexual dysfunction. Although most women were reluctant to perform mutilation on their daughters, more educational Actions are suggested to educate women about the impact of female mutilation on their sexual function. Counseling programs are also recommended to improve the sexual function of mutilated women.

The impact of probiotic supplementation on metabolic health in healthy women of reproductive age: a systematic review

2020 ◽  
Vol 11 (12) ◽  
pp. 10279-10289
Author(s):  
David F. Byrne ◽  
Aisling A. Geraghty ◽  
Cara A. Yelverton ◽  
Eileen F. Murphy ◽  
Douwe Van Sinderen ◽  
...  
Keyword(s):  
Systematic Review ◽  
At Risk ◽  
Disease Risk ◽  
Metabolic Health ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Preventative Measure ◽  
Probiotic Supplementation ◽  
Healthy Women ◽  
The Impact

Products containing probiotics are targeted at healthy or at-risk individuals as a preventative measure to minimise disease risk.

scholarly journals Double Burden of Malnutrition among Chinese Women of Reproductive Age and Their Social Determinants

Nutrients ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 3102
Author(s):  
Jingqi Song ◽  
Ji Zhang ◽  
Wafaie Fawzi ◽  
Yangmu Huang
Keyword(s):  
Normal Weight ◽  
Overweight And Obesity ◽  
Living Environment ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Double Burden ◽  
Community Factors ◽  
Wide Range ◽  
Double Burden Of Malnutrition ◽  
The Impact

This study aimed to examine the impact of a wide range of demographic, socioeconomic, and community factors on the double burden of malnutrition among women of reproductive age using longitudinal data. We used data about 11,348 women of reproductive age who participated in the China Health and Nutrition Survey (CHNS), a longitudinal survey, between 1989 and 2015. Nutritional outcomes were categorized into four groups, namely underweight, normal weight, overweight, and obesity, with normal weight as reference. A multinomial logit model was fitted due to geographic clustering and repeated observations of individuals. The prevalence of underweight decreased over time from 1991 but has tended to rise again since 2004, while the prevalence of overweight/obesity continued to rise between 1991 and 2015. Improved individual factors, socioeconomic status, and community urbanization reduced the risk of underweight but elevated the risk of overweight and obesity. The medium levels, rather than the highest levels, of household income and community urbanization are associated with a higher risk of overweight and obesity. The notable increase in underweight prevalence is a cause for concern to be addressed along with efforts to curb the rising tide of overweight. In order to enhance the nutritional status of women of reproductive age, it is essential to improving the community environment, levels of education, and living environment from a wider context. Long-term and targeted plans are urgently needed for nutrition improvements among the different populations.

scholarly journals Understanding the Impact of Uterine Fibroids on Human Endometrium Function

2021 ◽  
Vol 9 ◽  
Author(s):  
Antonia Navarro ◽  
Maria Victoria Bariani ◽  
Qiwei Yang ◽  
Ayman Al-Hendy
Keyword(s):  
Transforming Growth Factor ◽  
Vascular System ◽  
Uterine Fibroids ◽  
Transforming Growth Factor Β ◽  
Uterine Wall ◽  
Reproductive Age ◽  
Menstrual Bleeding ◽  
Women Of Reproductive Age ◽  
Myometrial Cells ◽  
The Impact

Uterine fibroids (leiomyomas) are the most common benign gynecological tumors in women of reproductive age worldwide. They cause heavy menstrual bleeding, usually leading to severe anemia, pelvic pain/pressure, infertility, and other debilitating morbidities. Fibroids are believed to be monoclonal tumors arising from the myometrium, and recent studies have demonstrated that fibroids actively influence the endometrium globally. Studies suggest a direct relationship between the number of fibroids removed and fertility problems. In this review, our objective was to provide a complete overview of the origin of uterine fibroids and the molecular pathways and processes implicated in their development and growth, which can directly affect the function of a healthy endometrium. One of the most common characteristics of fibroids is the excessive production of extracellular matrix (ECM) components, which contributes to the stiffness and expansion of fibroids. ECM may serve as a reservoir of profibrotic growth factors such as the transforming growth factor β (TGF-β) and a modulator of their availability and actions. Fibroids also elicit mechanotransduction changes that result in decreased uterine wall contractility and increased myometrium rigidity, which affect normal biological uterine functions such as menstrual bleeding, receptivity, and implantation. Changes in the microRNA (miRNA) expression in fibroids and myometrial cells appear to modulate the TGF-β pathways and the expression of regulators of ECM production. Taken together, these findings demonstrate an interaction among the ECM components, TGF-β family signaling, miRNAs, and the endometrial vascular system. Targeting these components will be fundamental to developing novel pharmacotherapies that not only treat uterine fibroids but also restore normal endometrial function.

scholarly journals Gut Microbiota Composition Changes in Constipated Women of Reproductive Age

2021 ◽  
Vol 10 ◽  
Author(s):  
Hongxia Li ◽  
Jianwei Chen ◽  
Xiaojing Ren ◽  
Chuanli Yang ◽  
Shuai Liu ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Chronic Constipation ◽  
Reproductive Age ◽  
Rrna Gene ◽  
Pathophysiological Mechanism ◽  
Healthy Controls ◽  
Women Of Reproductive Age ◽  
Microbial Composition ◽  
Hormone Levels ◽  
The Impact

BackgroundChronic constipation is one of the most prevalent functional gastrointestinal disorders, yet its etiology is multifactorial, and the pathophysiological mechanism is still unclear. Previous studies have shown that the gut microbiota of constipated patients differs from healthy controls; however, many discrepancies exist in the findings, and no clear link has been confirmed between chronic constipation and changes in the gut microbiota. Growing evidence indicates that age, gender, and hormone levels can affect the composition of gut microbiota. The aim of this study is to examine the overall changes in gut microbiota within a specific sub-population of patients, namely, constipated women of reproductive age.MethodsWe carried out a cross-sectional study comparing the fecal microbial composition of 30 healthy women and 29 constipated women using 16S rRNA gene sequencing. Only women of reproductive age were recruited to reduce the effects of age, gender, and hormone levels on the microbiome, and to prevent conflating the impact of these factors with the effects of constipation.ResultsThere were obvious differences in the gut microbiota in constipated women of reproductive age compared with the healthy controls, manifesting mainly as a significant increase in the abundance of Bacteroides (p < 0.05) and a significant decrease in the abundance of Proteobacteria (p < 0.01). The overall composition of the gut microbiota in each group was different, which was reflected in the ratios of Firmicutes to Bacteroidetes (F/B), which was 1.52 in the constipated group vs. 2.21 in the healthy group. Additionally, there was a significant decrease in butyrate-producing bacteria, like Roseburia and Fusicatenibacter (p < 0.01).ConclusionThe overall composition of the gut microbiota changed in constipated women of reproductive age, characterized by a loss in Proteobacteria and an increase in Bacteroidetes. Furthermore, the abundance of some butyrate-producing bacteria also reduced. These changes may reflect the unique interactions between host and some bacteria, or some bacterial metabolic products, which may be important targets for future studies to explore the pathogenesis of constipation.

Endometriosis and Infertility: The Impact on Quality of Life and Mental Health

2017 ◽  
Vol 9 (2) ◽  
pp. 112-115 ◽  
Author(s):  
Salvatore Giovanni Vitale ◽  
Valentina Lucia La Rosa ◽  
Agnese Maria Chiara Rapisarda ◽  
Antonio Simone Laganà
Keyword(s):  
Quality Of Life ◽  
Mental Health ◽  
Multidisciplinary Approach ◽  
Well Being ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Fertility Problems ◽  
The Impact

Endometriosis is one of the most common gynaecological diseases and has an incidence of about 6%-10% in women of reproductive age. It has been estimated that 50% of women with fertility problems have endometriosis. The management of infertility associated with endometriosis is difficult and controversial and it is important to provide a multidisciplinary approach in order to reduce the impact of these diseases on psychological and emotive well-being of affected women, as much as possible.

scholarly journals Deworming women of reproductive age during adolescence and pregnancy: what is the impact on morbidity from soil-transmitted helminths infection?

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Carolin Vegvari ◽  
Federica Giardina ◽  
Sumali Bajaj ◽  
Veronica Malizia ◽  
Robert J. Hardwick ◽  
...  
Keyword(s):  
Adolescent Girls ◽  
Egg Production ◽  
Reproductive Age ◽  
World Health ◽  
Age Group ◽  
Women Of Reproductive Age ◽  
Soil Transmitted Helminths ◽  
Force Of Infection ◽  
Pregnancy And Lactation ◽  
The Impact

Abstract Background Soil-transmitted helminths (STHs) are a major cause of poor health in low- and middle-income countries. In particular, hookworm is known to cause anaemia in children and women of reproductive age (WRA). One goal of the World Health Organization’s (WHO) 2030 roadmap for neglected tropical diseases is to reduce STH-related morbidity in WRA. As a minimal intervention, the WHO recommends deworming adolescent girls annually during human papilloma virus vaccination programmes and WRA during pregnancy and lactation. These routine interventions are low cost and can be implemented even by the most basic health services in endemic countries. In this study we use a cohort model to investigate the potential impact on STH-related morbidity in WRA. Results Annual deworming treatment of adolescent girls reduces the prevalence of moderate- and heavy-intensity infections in this age group by up to 60% in moderate transmission settings and by 12–27% in high transmission settings. Treatment of WRA during pregnancy and lactation on its own has a small (< 20%) but significant effect on morbidity although it does not lead to the achievement of the morbidity target (< 2% moderate- to high-intensity infections) in this age group. However, depending on the age-intensity profile of infection, which may vary geographically, and assumptions on the density-dependence of egg production by fertilised female worms, continued school-based treatment may be able to reduce the force of infection acting on WRA, both through an indirect effect on the overall population-based force of infection and via reducing the burden of infection as children age and move into the WRA age classes. As a result, morbidity in WRA may be eliminated. Conclusion While deworming during pregnancy and lactation does not lead to the achievement of the morbidity target in WRA and its efficacy may vary by setting, it is still expected to be beneficial for maternity and child health. Monitoring of any WRA-based intervention is recommended to evaluate its effectiveness.

scholarly journals Recommendations of the AGG (Section Maternal Disease) for Myasthenia Gravis in Pregnancy

2021 ◽  
Vol 81 (12) ◽  
pp. 1301-1306
Author(s):  
Maritta Kühnert ◽  
Markus Schmidt ◽  
Bettina Kuschel ◽  
Ute Margaretha Schäfer-Graf
Keyword(s):  
Myasthenia Gravis ◽  
Young Women ◽  
Fetal Monitoring ◽  
Reproductive Age ◽  
Women Of Reproductive Age ◽  
Clinical Presentations ◽  
Muscle Groups ◽  
Maternal Disease ◽  
The Impact ◽  
In Pregnancy

AbstractMyasthenia gravis is an autoimmune disease with a range of clinical presentations which manifest as combinations of weakness of the ocular, bulbar, and respiratory muscle groups and muscles of the extremities. Young women of reproductive age are most commonly affected. Preconception planning, the impact of pregnancy, prepartum management, drug therapy in pregnancy, myasthenic and cholinergic crises, fetal monitoring, peripartum management including analgesia and anesthesia during labor and cesarean section as well as neonatal management and neonatal myasthenia gravis are described here and the appropriate recommendations are given.

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