P85 QUANTIFICATION OF INTRAOPERATIVE FLUORESCENCE ANGIOGRAPHY TO ASSESS ANASTOMOTIC PERFUSION DURING GASTROINTESTINAL SURGERY: A SYSTEMATIC REVIEW

2019 ◽  
Vol 32 (Supplement_2) ◽  
Author(s):  
M D Slooter¹ ◽  
M Mansvelders¹ ◽  
P R Bloemen ◽  
S S Gisbertz¹ ◽  
W A Bemelman¹ ◽  
...  
Keyword(s):  
Systematic Review ◽  
Large Scale ◽  
Gastrointestinal Surgery ◽  
Fluorescent Imaging ◽  
Fluorescence Angiography ◽  
Future Research ◽  
Fluorescence Signal ◽  
Pixel Intensity ◽  
Meta Analyses ◽  
Intraoperative Fluorescence

Abstract Aim In this systematic review we aimed to identify all quantitative fluorescent parameters of intraoperative fluorescence angiography (IFA) during gastrointestinal surgery to pave way for a threshold that could predict anastomotic leakage (AL). Background &Methods In the last decade quantification of IFA using indocyanine green is attempted to objectively evaluate anastomotic perfusion during gastrointestinal surgery. In this systematic review, we adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A literature search of PubMed and Embase was performed. Articles were included when IFA was performed to assess gastrointestinal perfusion in both animal and human and analysed the fluorescence signal using quantitative fluorescent parameters. A fluorescent parameter was defined as ‘quantitative’ when a diagnostic numeral threshold for AL could potentially be produced. Results Some 1317 articles were identified, of which 23 were included in this review. Eight applied IFA during upper and fifteen during lower gastrointestinal surgery. The quantitative fluorescent parameters were divided into four categories: (1) time to fluorescence (n=19), (2) contrast-to-background ratio (n=3), (3) pixel intensity (n=3), and (4) numeral classification score (n=2). The first category was subdivided into (a) time to fluorescent enhancement (n=7) and (b) fluorescent-time curves (n=12). Thirteen studies correlated the fluorescent parameters to the occurrence of AL. Cut-off values for AL were derived for time to fluorescent enhancement (speed in gastric conduit wall) and derivatives of the fluorescent-time curves (Fmax, T1/2, TR, and slope). Conclusion Of the four categories, time to fluorescent enhancement seems the most promising quantitative parameter for clinical usage, as development of a cut-off value is possible on a large scale in the near future and no software is required. Future research might want to focus on fluorescent-time curves, as many different parameters can be derived and the fluorescence intensity can be bypassed. However, consensus on study set-up, and calibration of the different fluorescent imaging systems and software programs is mandatory to allow future data aggregation.

scholarly journals Defining indocyanine green fluorescence to assess anastomotic perfusion during gastrointestinal surgery: systematic review

BJS Open ◽  
2021 ◽  
Vol 5 (2) ◽  
Author(s):  
M D Slooter ◽  
M S E Mansvelders ◽  
P R Bloemen ◽  
S S Gisbertz ◽  
W A Bemelman ◽  
...  
Keyword(s):  
Systematic Review ◽  
Indocyanine Green ◽  
Patient Outcomes ◽  
Gastrointestinal Surgery ◽  
Fluorescence Angiography ◽  
Future Research ◽  
Fluorescence Signal ◽  
Pixel Intensity ◽  
Indocyanine Green Fluorescence ◽  
Quantitative Parameters

Abstract Background The aim of this systematic review was to identify all methods to quantify intraoperative fluorescence angiography (FA) of the gastrointestinal anastomosis, and to find potential thresholds to predict patient outcomes, including anastomotic leakage and necrosis. Methods This systematic review adhered to the PRISMA guidelines. A PubMed and Embase literature search was performed. Articles were included when FA with indocyanine green was performed to assess gastrointestinal perfusion in human or animals, and the fluorescence signal was analysed using quantitative parameters. A parameter was defined as quantitative when a diagnostic numeral threshold for patient outcomes could potentially be produced. Results Some 1317 articles were identified, of which 23 were included. Fourteen studies were done in patients and nine in animals. Eight studies applied FA during upper and 15 during lower gastrointestinal surgery. The quantitative parameters were divided into four categories: time to fluorescence (20 studies); contrast-to-background ratio (3); pixel intensity (2); and numeric classification score (2). The first category was subdivided into manually assessed time (7 studies) and software-derived fluorescence–time curves (13). Cut-off values were derived for manually assessed time (speed in gastric conduit wall) and derivatives of the fluorescence–time curves (Fmax, T1/2, TR and slope) to predict patient outcomes. Conclusion Time to fluorescence seems the most promising category for quantitation of FA. Future research might focus on fluorescence–time curves, as many different parameters can be derived and the fluorescence intensity can be bypassed. However, consensus on study set-up, calibration of fluorescence imaging systems, and validation of software programs is mandatory to allow future data comparison.

A Systematic Review of Meta-Analyses in Special Education: Exploring the Evidence Base for High-Leverage Practices

2021 ◽  
pp. 074193252110634
Author(s):  
Gena Nelson ◽  
Sara Cothren Cook ◽  
Kary Zarate ◽  
Sarah R. Powell ◽  
Daniel M. Maggin ◽  
...  
Keyword(s):  
Systematic Review ◽  
Special Education ◽  
Students With Disabilities ◽  
Special Education Teachers ◽  
Evidence Base ◽  
Future Research ◽  
Evidence Based Practices ◽  
Intensive Instruction ◽  
Disability Categories ◽  
Meta Analyses

It is crucial that special education teachers are equipped with the knowledge and skills necessary to improve outcomes for students with disabilities. Despite federal legislation and efforts of the field to identify and disseminate evidence-based practices for students with disabilities, it is uncertain whether all special education teachers provide instruction based on the best available research. To better prepare special education teachers, McLeskey et al. proposed 22 high-leverage practices (HLPs). We conducted this systematic review of meta-analyses to provide an initial investigation of the experimental evidence reporting on the effectiveness of the HLPs for students with, or at risk for, a disability. Results indicated the largest amount of evidence from meta-analyses related to intensive instruction, explicit instruction, and social skills, with few meta-analyses reporting on collaboration and assessment. The results highlighted disproportional evidence according to disability categories. Implications for future research, practice, and teacher education are discussed.

scholarly journals Obsessive healthy eating and orthorexic eating tendencies in sport and exercise contexts: A systematic review and meta-analysis

2021 ◽  
Author(s):  
Jana Strahler ◽  
Hanna Wachten ◽  
Anett Mueller-Alcazar
Keyword(s):  
Systematic Review ◽  
Gender Differences ◽  
Healthy Eating ◽  
Meta Analysis ◽  
Group Analysis ◽  
Future Research ◽  
Exercise Behaviors ◽  
Sport And Exercise ◽  
Underlying Mechanisms ◽  
Meta Analyses

AbstractBackgroundOrthorexia Nervosa (ON) and exercise addiction (ExAdd) are two phenomena believed to overlap. We conducted a meta-analysis exploring the link between ON and (addictive) exercise behaviors.MethodsA systematic review of major databases and gray literature was carried out for studies reporting on ON and (addictive) exercise behaviors. Random effects meta-analyses were undertaken calculating correlations between ON and (addictive) exercise behaviors. A sub-group analysis investigated gender differences.ResultsTwenty-five studies with 10,134 participants (mean age = 25.21; 56.4% female) were included. Analyses showed a small overall correlation between ON and exercise (21 studies, r = 0.12, 95% CI |0.06–0.18|) and a medium overall correlation between ON and ExAdd (7 studies, r = 0.29, 95% CI |0.13–0.45|). Gender differences were negligible.ConclusionsOrthorexic eating correlated slightly and moderately with exercise and ExAdd, respectively, expressing some unique and shared variance of these behaviors. While this does not suggest ON and addictive exercising to be independent, it does not indicate substantial comorbidity. Future research should focus on clinical relevance, underlying mechanisms, vulnerability, and risk factors.

Factors associated with dementia-related stigma and associated domains in adolescents: A Systematic Review Protocol v1

2021 ◽  
Author(s):  
Mrs Esra Hassan ◽  
Prof Naji Tabet ◽  
n.farina not provided
Keyword(s):  
Systematic Review ◽  
Data Extraction ◽  
Future Research ◽  
Factors Associated ◽  
Related Stigma ◽  
Review Protocol ◽  
Learning Software ◽  
Meta Analyses ◽  
Theses And Dissertations ◽  
Appraisal Tool

Background: To develop evidence-based anti-stigma programmes for adolescents, underlying factors that drive dementia-related stigma in adolescents need to be captured. However, it is unclear which factors play a role in dementia attitude formation in adolescents. This is a protocol for a systematic review that will seek to identify factors associated with dementia attitudes in adolescents (10-18 years old). Methods: A systematic search strategy will be used to identify observational data in which factors are associated with dementia-related stigma and associated domains (e.g. attitudes, beliefs, perceptions). Systematic searches for articles will be conducted in the following databases: PubMed, PsycInfo, Web of Science, SCOPUS and Open Access Theses and Dissertations. Titles and abstracts will be screened with the assistance of machine learning software (ASReview), prior to reviewing full texts. Following data extraction, quality assessment of study and risk of bias will be assessed using the mixed methods appraisal tool (MMAT). The protocol is written in line with the Preferred Reporting Items for Systematic Reviews and Meta-analyses Protocol (PRISMA-P) guidelines. Results: Descriptive data of the studies will be reported in tables and summarised narratively and split into thematic headings guided by the results of the systematic review. Identifying which factors are implicated in attitudes towards people living with dementia will allow researchers to be better informed in which factors may be a useful target for more tailored and effective dementia related anti-stigma-initiatives. Discussion: The findings from this systematic review will help guide future research to identify groups that may be at the greatest risk of developing stigmatising attitudes and potential targets for future intervention.

scholarly journals Pedestrian–Vehicle Interaction at Unsignalized Crosswalks: A Systematic Review

2020 ◽  
Vol 12 (7) ◽  
pp. 2805 ◽  
Author(s):  
Harley Amado ◽  
Sara Ferreira ◽  
José Pedro Tavares ◽  
Paulo Ribeiro ◽  
Elisabete Freitas
Keyword(s):  
Systematic Review ◽  
Data Collection ◽  
Cellular Automata ◽  
Systematic Reviews ◽  
Video Camera ◽  
Future Research ◽  
Cellular Automata Model ◽  
Micro Simulation ◽  
Field Information ◽  
Meta Analyses

A systematic review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), to generate a document that supports the development of future research, compiling the various studies focused on the analysis of the pedestrian-vehicle interaction at unsignalized crosswalks. Firstly, 381 studies were identified by applying the search protocol in the database sources; however, only nine studies were included in this review because most of the studies are not focused on this type of crosswalks or have not considered the micro-simulation perspective. For each study, an analysis of the used methodology for data collection was carried out, in addition to what type of model it was applied, including the variables that represent the PVI (Pedestrian-Vehicle Interaction). The outcomes obtained by this systematic review show that although the video camera observation technique is the most used, it is possible to complement them with other tools to add specific field information. Additionally, variables such as the adjacent yields, speed variables vehicles, pedestrian attitude, and the number of pedestrians waiting at the crossing were those most used in the cellular automata model or micro-simulation, which are the commonly developed models to simulate this interaction.

scholarly journals Network meta-analyses for EGFR mutation-positive non-small-cell lung cancer: systematic review and overview of methods and shortcomings

2020 ◽  
Vol 9 (17) ◽  
pp. 1179-1194
Author(s):  
Carl Samuelsen ◽  
Ingolf Griebsch
Keyword(s):  
Lung Cancer ◽  
Systematic Review ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Kinase Inhibitors ◽  
Egfr Mutation ◽  
Small Cell ◽  
Future Research ◽  
Small Cell Lung ◽  
Meta Analyses

Aim: To perform a review of network meta-analyses (NMAs) for the first-line treatment of EGFR mutation-positive non-small-cell lung cancer, and to provide an overview of methodological approaches and potential shortcomings. Materials & methods: We conducted a systematic review of NMAs and evaluated their methodologies, including inclusion/exclusion criteria, information sources, results and outcomes, and statistical methodologies. Results: We identified ten published NMAs using five archetypical network structures. Despite similar objectives, there was substantial variability in the number of trials included in each NMA and in the relative treatment efficacy of the tyrosine kinase inhibitors. Conclusion: We identified methodological issues to explain differences in the findings, criteria for inclusion in NMAs and the degree of lumping of treatments. These factors should be given particular consideration in future research.

scholarly journals A systematic review of the association between emotions and eating behaviour in normal and overweight adult populations

2017 ◽  
Vol 24 (1) ◽  
pp. 3-24 ◽  
Author(s):  
Tracey J Devonport ◽  
Wendy Nicholls ◽  
Christopher Fullerton
Keyword(s):  
Systematic Review ◽  
Standard Deviation ◽  
Emotional Eating ◽  
Eating Behaviour ◽  
Quality Analysis ◽  
Future Research ◽  
Eating Behaviours ◽  
Overweight Adult ◽  
Methodological Considerations ◽  
Meta Analyses

A systematic review was completed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. A comprehensive search of four electronic databases (2004–2015) yielded 60,017 articles, of which 29 met inclusion criteria. Included studies performed poorly on data quality analysis in terms of randomisation and controlling for confounding factors. Participant’s body mass index scores range from 19.73 (standard deviation = 1.54) to 28.4 (standard deviation = 1.4) kg/m2. Where positive and negative affects were compared, food was more likely to be consumed in response to positive affect. With regard to discrete emotions; stress, depression and sadness consistently elicited eating behaviours that fall outside of nutritional recommendations (e.g. increased food intake or poor nutritional food choices). The role of moderators including individual differences in dietary restraint and emotional eating, as well as methodological considerations, such as means of eliciting and measuring emotions, may account for equivocality with regard to some emotion and eating associations. This article concludes with recommendations for future research and implications for practice.

scholarly journals A SYSTEMATIC REVIEW AND META-ANALYSIS OF AGE-RELATED DIFFERENCES IN TRUST

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S477-S477
Author(s):  
Phoebe E Bailey ◽  
Tarren Leon
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Young Adults ◽  
Meta Analysis ◽  
Self Report ◽  
Future Research ◽  
Age Group ◽  
Age Related ◽  
Meta Analyses ◽  
Effect Of Age

Abstract This systematic review and meta-analysis quantifies the magnitude and breadth of age-related differences in trust. Thirty-eight independent data sets met criteria for inclusion. Overall, there was a moderate effect of age group on trust (g = 0.22), whereby older adults were more trusting than young adults. Three additional meta-analyses assessed age-related differences in trust in response to varying degrees of trustworthiness. This revealed that older adults were more trusting than young adults in response to neutral (g = 0.31) and negative (g = 0.33), but not positive (g = 0.15), indicators of trustworthiness. The effect of age group on trust in response to positive and neutral cues was moderated by type of trust (financial vs. non-financial) and type of responding (self-report vs. behavioral). Older adults were more trusting than young adults in response to positive and neutral indicators of trustworthiness when trust was expressed non-financially, but not financially. There was also an age-related increase in self-reported, but not behavioral, trust in response to neutral cues. Older adults were more trusting than young adults in response to negative indicators of trustworthiness regardless of the type of trust or type of responding. The reliability of information about trustworthiness (superficial vs. genuine cues) did not moderate any effects of age on trust. Implications of these findings and directions for future research are discussed.

scholarly journals A Critical-Systematic Review of the Interactions of Biochar with Soils and the Observable Outcomes

2021 ◽  
Vol 13 (24) ◽  
pp. 13726
Author(s):  
Jackson Nkoh Nkoh ◽  
M. Abdulaha-Al Baquy ◽  
Shamim Mia ◽  
Renyong Shi ◽  
Muhammad Aqeel Kamran ◽  
...  
Keyword(s):  
Soil Properties ◽  
Large Scale ◽  
Chemical Properties ◽  
Nutrient Content ◽  
Biological Properties ◽  
Plant Performance ◽  
Future Research ◽  
Soil Microbial Community Structure ◽  
Soil Microbial ◽  
Meta Analyses

Biochar research has experienced a significant increase in the recent two decades. It is growing quickly, with hundreds of reviews, including meta-analyses, that have been published reporting diverse effects of biochar on soil properties and plant performance. However, an in-depth synthesis of biochar–soil interactions at the molecular level is not available. For instance, in many meta-analyses, the effects of biochar on soil properties and functions were summarized without focusing on the specificity of the biochar and soil properties. When applied to soils, biochar interacts with different soil components including minerals, organic matter, gases, liquids, and nutrients, while it also changes soil microbial community structure and their occurrence. These different interactions modify soil physicochemical properties with consequences for dynamic changes in nutrient availability and, thus, plant performance. This review systematically analyzed biochar effects on soil properties and functions: (a) soil physical properties; (b) chemical properties; (c) biological properties; and (d) functions (plant performance, nutrient cycling, etc.). Our synthesis revealed that the surface properties of biochar (specific surface area and charge) and its associated nutrient content determine its role in the soil. At the same time, the extent of changes depends on soil properties, suggesting that both biochar and soil properties need to be considered for harvesting benefits of biochar application. Altogether, we believe our synthesis will provide a guide for researchers and practitioners for future research as well as large-scale field applications.

scholarly journals Blockchain Technology Meets Traceability in Fruit Supply Chain Management: A Systematic Review

2021 ◽  
Vol 12 (3) ◽  
pp. 232-238
Author(s):  
Resista Vikaliana ◽  
Raja Zuraidah Raja Mohd Ras ◽  
I Nyoman Pujawan ◽  
Irwansyah
Keyword(s):  
Systematic Review ◽  
Supply Chain ◽  
Supply Chain Management ◽  
Future Research ◽  
Supply Chain System ◽  
Chain Management ◽  
Traceability System ◽  
Future Research Agenda ◽  
Blockchain Technology ◽  
Meta Analyses

Fruits are easily damaged, therefore, a tracing system is needed to ensure the commodity is well received by consumers.  This study is a systematic review aims to  identify areas where the fruits traceability provides the most value for supply chain management and  to develop elements of a future research agenda for the fruits traceability in supply chain management.  PRISMA or Preferred Reporting Items for Systematic Reviews and Meta-Analyses is used to help the systematic literature review.  The result showed thad there are several values ​​in applying traceability to the fruit supply chain, such as traceability guarantees the quality of fruit in the supply chain, traceability protects from fraud.  Traceability will help increase consumer confidence in food safety, particularly on fruit.  Blockchain technology  is a promosing technology for a   traceability system in industry and can be used successfully, by modifying the supply chain system and meeting the limitations first.

Sign in / Sign up

Export Citation Format

Share Document