scholarly journals Hydration status, BMI and troponin as factors of an impaired exercise tolerance in women over 40 with arterial hypertension

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
A.M Bielecka-Dabrowa ◽  
K Gryglewska ◽  
A Sakowicz ◽  
K Janikowski ◽  
M Maciejewski ◽  
...  
Keyword(s):  
Heart Failure ◽  
At Risk ◽  
Water Content ◽  
Body Mass ◽  
Early Identification ◽  
Cardiac Troponin ◽  
Peak Velocity ◽  
Body Water ◽  
Hydration Status ◽  
Mitral Annulus Velocity

Abstract Purpose The aim was to identify factors influencing maximal oxygen uptake (VO2max) and early identification of hypertensive women at risk of heart failure (HF). Methods The 185 consecutive females with controlled hypertension were divided according VO2max quartiles. The patients underwent echocardiography, non-invasive body mass analysis, spiroergometry and hemodynamic parameters. Regression analyses determined predictors of the lowest VO2max (quartile 1: VO2max <17 ml/kg/min). Results Females with the worst oxygen consumption had significantly higher level of high sensitive cardiac Troponin T (hs-cTnT) [p=0.001], higher values of the left atrial (LA) volume, late diastolic mitral annulus velocity (A'), ratio of peak velocity of early diastolic transmitral flow to peak velocity of early diastolic mitral annular motion (E/E') [p=0.0003, p=0.02, p=0.04; respectively] and lower E' [p=0.001] compared to controls. Women with the worst exercise capacity had higher body mass index (BMI) and fat content (kg and %) [p<0.0001], higher fat free mass (FFM) (kg) [p<0.0001], higher total body water content (TBW) [p=0.0002] as well as extracellular body water content (ECW) [p<0.0001] and intracellular body water content (ICW) [p=0.005], ECW/TBW x 100% [p<0.0001] and metabolic age [p<0.0001] compared to counterparts. In a multiple logistic regression model independently associated with VO2max were: ECW/TBW x 100% (OR 4.45, 95% CI: 1.77–11.21; p=0.002) Figure 1, BMI (OR 7.11, 95% CI: 2.01–25.11; p=0.002) Figure 2 and hs-cTnT level (OR 2.69, 95% CI: 1.23–5.91; p=0.013). Conclusions High-sensitivity cardiac troponin may serve as early biomarker of heart failure in hypertensive women. Hydration status should be considered in overall hypertensive women care. There is an importance of body mass compartments analysis in early identification of hypertensive females at risk of heart failure. FUNDunding Acknowledgement Type of funding sources: Public grant(s) – National budget only. Main funding source(s): The Project is financed by the Polish National Agency for Academic Exchange under the Foreign Promotion Programme. Figure 1 Figure 2

scholarly journals Factors and Prognostic Significance of Impaired Exercise Tolerance in Women over 40 with Arterial Hypertension

2021 ◽  
Vol 11 (8) ◽  
pp. 759
Author(s):  
Agata Bielecka-Dabrowa ◽  
Katarzyna Gryglewska ◽  
Agata Sakowicz ◽  
Stephan von Haehling ◽  
Kamil Janikowski ◽  
...  
Keyword(s):  
Heart Failure ◽  
At Risk ◽  
Water Content ◽  
Early Identification ◽  
Cardiac Troponin ◽  
Troponin T ◽  
Prognostic Significance ◽  
Body Water ◽  
Hydration Status ◽  
Mitral Annulus Velocity

The aim of this study was to identify factors influencing maximal oxygen uptake (VO2max) and early identification of the profile of hypertensive women in the perimenopausal period at risk of heart failure. This study included 185 female patients. Regression analyses determined predictors of the lowest VO2max (quartile 1: VO2max < 17 mL/kg/min). Females with the lowest oxygen consumption had a significantly higher level of high sensitive cardiac Troponin T (hs-cTnT) (p = 0.001), higher values of the left atrial (LA) volume, late diastolic mitral annulus velocity (A′), E/E′ (p = 0.0003, p = 0.02, p = 0.04; respectively), higher BMI and fat content (kg and %) (p < 0.0001), higher fat free mass (FFM) (kg) (p < 0.0001), total body water content (TBW) (p = 0.0002) as well as extracellular body water content (ECW) (p < 0.0001) and intracellular body water content (ICW) (p = 0.005), ECW/TBW × 100% (p < 0.0001) and metabolic age (p < 0.0001) and lower E′ (p = 0.001) compared to controls. In a multiple logistic regression model independently associated with VO2max were: ECW/TBW × 100% (OR 4.45, 95% CI: 1.77–11.21; p = 0.002), BMI (OR 7.11, 95% CI: 2.01–25.11; p = 0.002) and hs-cTnT level (OR 2.69, 95% CI: 1.23–5.91; p = 0.013). High-sensitivity cardiac troponin may serve as an early biomarker of heart failure in hypertensive women. Hydration status should be considered in overall hypertensive women care. There is an importance of body mass compartments analysis in the early identification of hypertensive females at risk of heart failure. Optimization and personalization of body structure may be a preventive method for this disease. ClinicalTrials.gov Identifier: NCT04802369.

P2607Quick nutritional assessment and prognosis in outpatients with heart failure with mid-range ejection fraction

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
E Zamora ◽  
B Gonzalez ◽  
C Rivas ◽  
V Diaz ◽  
P Velayos ◽  
...  
Keyword(s):  
Heart Failure ◽  
Body Mass Index ◽  
At Risk ◽  
Ejection Fraction ◽  
Nutritional Status ◽  
Body Mass ◽  
Screening Tool ◽  
Nutritional Assessment ◽  
Functional Class ◽  
Nyha Functional Class

Abstract Background Nutritional status is an important prognostic factor in patients with heart failure (HF) beyond body mass index, although its prognostic value in patients with mid-range left ventricular ejection fraction (HFmrEF) is not completely elucidated. In a pilot study we observed that the Mini Nutritional Assessment Short Form (MNA-SF) was the best approach for the screening of nutritional status in HF outpatients over others screening tools. Purpose To assess the prognostic role of malnutrition or risk of malnutrition in HFmrEF outpatients after the implementation of the MNA-SF screening tool in a routine way in a multidisciplinary HF. Methods The MNA-SF screening tool was administered during the global nurse evaluation of patients. The scoring ranges from 0 to 14, being 0 to7 as malnutrition status, 8 to 11 as at risk of malnutrition and 12 to 14 as normal nutritional status. For the present study those patients with malnutrition and at risk of malnutrition were merged and considered abnormal nutritional status. All-cause death was the primary end-point. Univariate and multivariate (backward conditional stepwise) Cox regression analyses were performed. Results Since October 2016 to November 2017, 153 HFmrEF patients were studied (mean age 68.8±11.7 years, 72.5% men, body mass index 28.4±4.4, LVEF 44% ± 3, NYHA class I 5.9%, II 86.3%, and III 7.8%). According to the MNA-SF 25 patients were (16.3%) fulfilled criteria of malnutrition (4) or where at risk of malnutrition (21). During a mean follow-up of 17.4±6.1 months, 23 patients died (15%). In the univariate analysis, nutritional abnormal status was significantly associated with all-cause death (HR 2.93 [1.23–7], p=0.02). In the multivariate analysis which included age, sex, NYHA functional class, body mass index, ischemic aetiology of HF and years of duration of HF, abnormal nutritional status remained significantly associated with all-cause mortality (HR 3.64 [1.39–9.54], p=0.009), together with NYHA functional class (HR 7.93 [2.69–23.4], p<0.001) and years of HF duration (HR 1.10 [1.04–1.16], p=0.001). Conclusions Nutritional status assessed with the screening MNA-SF was an independent predictor of all-cause death in ambulatory patients with HFmrEF – beyond BMI – together with NYHA functional class and HF duration.

Water homeostasis in desert-dwelling horses

1991 ◽  
Vol 71 (1) ◽  
pp. 112-117 ◽  
Author(s):  
J. C. Sneddon ◽  
J. G. van der Walt ◽  
G. Mitchell
Keyword(s):  
Water Content ◽  
Water Deprivation ◽  
Body Water ◽  
The Body ◽  
Hydration Status ◽  
Plasma Sodium ◽  
Namib Desert ◽  
Water Turnover ◽  
Feral Horses ◽  
Total Plasma Protein

This study set out to investigate tolerance of the body water pool to short-term water deprivation in horses and, in particular, to assess whether feral horses from the Namib Desert showed tolerance to dehydration superior to Transvaal. Hydration status was compared in six feral horses from the Namib Desert and in six Boerperd farm horses under conditions of normal hydration and after 72 h of dehydration. Under normal hydration, the two groups did not differ significantly in water intake, plasma sodium and potassium concentrations, plasma osmolality, hematocrit, total plasma protein, body water content, or water turnover (ml.kg-0.82.day-1). The Namib horses were significantly smaller (P less than 0.0001) and turned over 5 liters less water per day than the Boerperd during normal hydration and 4 liters less during dehydration. Increases in plasma sodium concentration after 72 h of dehydration were greater (P less than 0.05) in the Namib horses. It was concluded that horses can easily tolerate water deprivation that results in a 12% reductions in body mass. The feral horses of the Namib desert were not significantly different per unit mass from domestic horses with regard to indexes of total body water content under conditions of normal hydration and after 72 h of dehydration. Their smaller size and, hence, lower water turnover might be mechanisms they use for survival in the Namib Desert.

Metabolic Reference Standards for the Neonate

PEDIATRICS ◽  
1968 ◽  
Vol 41 (6) ◽  
pp. 1146-1147
Author(s):  
W. Burmeister
Keyword(s):  
Water Content ◽  
Body Mass ◽  
Total Body Water ◽  
Extracellular Fluid ◽  
Reference Standards ◽  
Body Water ◽  
Intracellular Water ◽  
Human Organism ◽  
The Difference ◽  
Total Body

I would like to comment on the article by J. C. Sinclair, et al. (Pediatrics, 39:724, 1967), "Metabolic Reference Standards for the Neonate." In the course of my work on the composition of the human organism, I also found the difference weight-extracellular fluid (= W-ECF). The fact that the composition of W-ECF is a rather constant one may be seen from the following calculation: if total body water content is assumed to be 71% of body mass with newborn and 61% with male adults, it follows that the proportion of intracellular water in W-ECF remains almost unchanged during growth.

scholarly journals Influence of Water Intake and Balance on Body Composition in Healthy Young Adults from Spain.

Nutrients ◽  
2019 ◽  
Vol 11 (8) ◽  
pp. 1923 ◽  
Author(s):  
García ◽  
Moráis-Moreno ◽  
Samaniego-Vaesken ◽  
Partearroyo ◽  
Varela-Moreiras
Keyword(s):  
Body Composition ◽  
Water Balance ◽  
Water Content ◽  
Water Intake ◽  
Fluid Intake ◽  
Public Health Problem ◽  
Overweight And Obesity ◽  
Body Water ◽  
International Standards ◽  
Hydration Status

The increasing prevalence of overweight and obesity has become an epidemic public health problem worldwide. In the last years, several investigations have suggested that water intake and retention could have important implications for both weight management and body composition. However, there is a lack of information about this issue globally, and mainly specifically in Spain. Thus, the aim of this study was to analyze the association between hydration status and body composition in a sample of healthy Spanish adults. The study involved 358 subjects, aged 18–39 years. The recently validated “hydration status questionnaire” was used to assess their water intake, elimination, and balance. Anthropometric measurements were performed according to the recommendations of the International Standards for Anthropometric Assessment (ISAK). Body composition variables were acquired by bioelectrical impedance analysis. Differences in anthropometric and body composition variables were assessed through the ANOVA test and considered significant at p < 0.05. Fluid intake was correlated with body water content. Inverse associations between water consumption, normalized by weight, with body weight, body fat mass, and waist circumference were found. Moreover, according to water balance, significant differences in body water content in females were observed. In conclusion, higher fluid intake seems to be related with a healthier body composition. Therefore, the improvement of water intake and water balance could be useful for overweight and obesity prevention, although further studies are needed to confirm the present findings.

Urinary Indices during Dehydration, Exercise, and Rehydration

1998 ◽  
Vol 8 (4) ◽  
pp. 345-355 ◽  
Author(s):  
Lawrence E. Armstrong ◽  
Jorge A. Herrera Soto ◽  
Frank T. Hacker ◽  
Douglas J. Casa ◽  
Stavros A. Kavouras ◽  
...  
Keyword(s):  
Specific Gravity ◽  
Body Mass ◽  
Urine Volume ◽  
Plasma Osmolality ◽  
Body Water ◽  
Hydration Status ◽  
Plasma Sodium ◽  
Oral Rehydration ◽  
Urine Color ◽  
Better Than

This investigation evaluated the validity and sensitivity of urine color (Ucol), specific gravity (Usg), and osmolality (Uosm) as indices of hydration status, by comparing them to changes in body water. Nine highly trained males underwent a 42-hr protocol involving dehydration to 3.7% of body mass (Day 1, −2.64 kg), cycling to exhaustion (Day 2, −5.2% of body mass, −3.68 kg), and oral rehydration for 21 hr. The ranges of mean (across time) blood and urine values were Ucol, 1-7; Usg, 1.004-1.029; U08m, 117-1,081 mOsm • kg−1; and plasma osmolality (Posm), 280-298 mOsm ⋅ kg−1. Urine color tracked changes in body water as effectively as (or better than) Uosm, Usg, urine volume, Posm, plasma sodium, and plasma total protein. We concluded that (a) Ucol, Uosm, and Usg are valid indices of hydration status, and (b) marked dehydration, exercise, and rehydration had little effect on the validity and sensitivity of these indices.

Early Identification of Youth at Risk for Suicidal Behavior

Crisis ◽  
2019 ◽  
Vol 40 (5) ◽  
pp. 326-332
Author(s):  
Ivonne Andrea Florez ◽  
Devon LoParo ◽  
Nakia Valentine ◽  
Dorian A. Lamis
Keyword(s):  
At Risk ◽  
Early Identification ◽  
Suicide Risk ◽  
Psychiatric Symptoms ◽  
Demographic Factors ◽  
Health Centers ◽  
Lack Of Information ◽  
Youth At Risk ◽  
Logistic Regressions ◽  
Lethal Means

Abstract. Background: Early identification and appropriate referral services are priorities to prevent suicide. Aims: The aim of this study was to describe patterns of identification and referrals among three behavioral health centers and determine whether youth demographic factors and type of training received by providers were associated with identification and referral patterns. Method: The Early Identification Referral Forms were used to gather the data of interest among 820 youth aged 10–24 years who were screened for suicide risk (females = 53.8%). Descriptive statistics and binary logistic regressions were conducted to examine significant associations. Results: Significant associations between gender, race, and age and screening positive for suicide were found. Age and race were significantly associated with different patterns of referrals and/or services received by youths. For providers, being trained in Counseling on Access to Lethal Means was positively associated with number of referrals to inpatient services. Limitations: The correlational nature of the study and lack of information about suicide risk and comorbidity of psychiatric symptoms limit the implications of the findings. Conclusion: The results highlight the importance of considering demographic factors when identifying and referring youth at risk to ensure standard yet culturally appropriate procedures to prevent suicide.

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