P5236An observational, international, cohort study to evaluate the satisfaction and preferences of patients in preventive treatment of secondary cardiovascular events with a cardiovascular polypill

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
J Cosin Sales ◽  
J M Murcia Zaragoza ◽  
H O Pereyra Rico ◽  
F De La Guia Galipienso
Keyword(s):  
Secondary Prevention ◽  
Ad Hoc ◽  
Disease Patient ◽  
Economic Cost ◽  
Preventive Treatment ◽  
Coronary Event ◽  
Current Treatment ◽  
Cross Sectional ◽  
Patient’S Satisfaction ◽  
Single Pill

Abstract Background/Introduction The term polypill was first described, as a combination of several drugs at fixed doses in a single pill with the aim of facilitating the taking of medication to patients, increasing adherence to treatment, as well as reducing the economic cost associated with this disease. Patient satisfaction may be associated with improved clinical outcomes. To date there are no data about the satisfaction and preferences of patients with this cardiovascular polypill as a treatment for the secondary prevention of cardiovascular disease (CVD) in Spain and Belgium. Purpose To evaluate the satisfaction of patients treated with the cardiovascular polypill containing acetylsalicylic acid (ASA), atorvastatin and ramipril compared with patients treated with ASA, a statin and an ACE inhibitor separately for the secondary prevention of CVD. Adherence and preference of patients treated with the cardiovascular polypill and with the monocomponents separately were also evaluated and compared. Methods An observational, cross-sectional, cohort, multicentre study in Spain and Belgium, was carried out. All patients included were stable regarding CVD (>1 year from acute coronary event). Patients were divided into two cohorts: those treated with the cardiovascular polypill and patients treated with the monocomponents separately for a minimum of 3 months. Patients from both cohorts were paired based on gender and age (± 5 years). Data on satisfaction was collected by the TSQM-9, adherence by the Morisky-Green test and ad hoc questions were asked to determine patient preferences. Results In total 314 patients were included in Spain and 21 in Belgium who were in current treatment for the secondary prevention of CVD with a combination that included ASA, a statin and an ACEI, or who were treated with the cardiovascular polypill at least in the last 3 months. Patients with the polypill had a higher level of satisfaction with the treatment received than patients treated with the monocomponents separately (p<0.0001). In total 72.8% of patients treated with the monocomponents separately declared that they would change to the polypill. And 65.2% of patients in Spain also stated that, they would pay additional cost for the polypill to change to a single capsule. Patients treated with the polypill (57.7%) had a significantly higher adherence than patients treated with the monocomponents separately (41.1%) (p=0.0027). Conclusions The validation of patient's satisfaction and preferences is crucial for the evaluation of the cardiovascular polypill versus its monocomponents separately. Patients treated with the polypill showed a significant higher degree of satisfaction and better adherence, whereas most patients receiving the monocomponents declared that they would prefer the polypill. Acknowledgement/Funding The study was conducted with a full grant from Ferrer Internacional S.A.

scholarly journals Evaluating patients' satisfaction and preferences with a secondary prevention cardiovascular polypill: the Aurora Study

2021 ◽  
Author(s):  
Juan Cosin-Sales ◽  
José M Murcia-Zaragoza ◽  
Hector O Pereyra-Rico ◽  
Fernando de la Guía-Galipienso ◽  
Kurt Hermans ◽  
...  
Keyword(s):  
Secondary Prevention ◽  
Multicenter Study ◽  
Patient Preferences ◽  
Treatment Satisfaction ◽  
Ad Hoc ◽  
Cardiovascular Prevention ◽  
Cross Sectional ◽  
Satisfaction Questionnaire ◽  
Patients Satisfaction ◽  
Secondary Cardiovascular Prevention

Aim: To evaluate the satisfaction, preferences and adherence of patients in secondary cardiovascular prevention treated with the CNIC cardiovascular polypill compared with patients treated with the separate monocomponents. Methods: Observational, cross-sectional and multicenter study. Satisfaction was evaluated by the Treatment Satisfaction Questionnaire for Medication 9 items, adherence by the Morisky-Green questionnaire and ad-hoc questions were asked regarding patient preferences. Results: Polypill patients reported higher satisfaction than patients treated with the monocomponents (77.3 vs 71.2%, p < 0.0001). 72.8% of patients treated with the monocomponents would prefer to change to the polypill. Patients treated with the polypill had significantly higher adherence than patients treated with the monocomponents (57.7 vs 41.1%) (p = 0.0027). Conclusion: Polypill patients show higher satisfaction and better adherence. Most patients receiving the monocomponents would prefer a polypill regime.

scholarly journals The Economic Cost of Diet and Its Association with Adherence to the Mediterranean Diet in a Cohort of Spanish Primary Schoolchildren

2021 ◽  
Vol 18 (3) ◽  
pp. 1282
Author(s):  
Rosario Pastor ◽  
Noemi Pinilla ◽  
Josep A. Tur
Keyword(s):  
Mediterranean Diet ◽  
Fast Food ◽  
Area Under The Curve ◽  
Economic Cost ◽  
Food Prices ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Old Spanish ◽  
Total Economic Cost ◽  
Data Frequency

Background: Adoption of a certain dietary pattern is determined by different factors such as taste, cost, convenience, and nutritional value of food. Objective: To assess the association between the daily cost of a diet and its overall quality in a cohort of 6–12-year-old Spanish schoolchildren. Methods: A cross-sectional survey was conducted on a cohort (n = 130; 47% female) of 6–12-year-old children schooled in primary education in the central region of Spain. Three-day 24 h records were administered, and the nutritional quality of the diet was also determined by means of Mediterranean Adequacy Index (MAI). A questionnaire on sociodemographic data, frequency of eating in fast-food restaurants, and supplement intake were also recorded. The person responsible for the child’s diet and the schooler himself completed the questionnaires, and homemade measures were used to estimate the size of the portions. Food prices were obtained from the Household Consumption Database of the Spanish Ministry of Agriculture, Fisheries and Food. The economic cost of the diet was calculated by multiplying the amount in grams of the food consumed by each child by the corresponding price in grams and adding up the total amount for each participant. The total economic cost of the diet was calculated in €/day and in €/1000 kcal/day. Results: The area under the curve (AUC) for €/day and €/1000 kcal/day represent 62.6% and 65.6%, respectively. According to AUC values, adherence to Mediterranean diet (MD) is a moderate predictor of the monetary cost of the diet. A direct relationship between the cost of the diet and the adherence to MD was observed [OR (€/1000 kcal/day) = 3.012; CI (95%): 1.291; 7.026; p = 0.011]. Conclusions: In a cohort of Spanish schoolchildren with low adherence to the MD, a higher cost of the diet standardized to 1000 kcal was associated with above-average MAI values.

scholarly journals Prevalence of SARS-CoV-2 Infection at the University of Barcelona during the Third COVID-19 Pandemic Wave in Spain

2021 ◽  
Vol 18 (12) ◽  
pp. 6526
Author(s):  
Sebastián Videla ◽  
Aurema Otero ◽  
Sara Martí ◽  
M. Ángeles Domínguez ◽  
Nuria Fabrellas ◽  
...  
Keyword(s):  
Ad Hoc ◽  
Venous Blood ◽  
Herd Immunity ◽  
Cross Sectional Study ◽  
Rt Pcr ◽  
Igg Antibody ◽  
Cross Sectional ◽  
Total Prevalence ◽  
The University ◽  
The Impact

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic started in December 2019 and still is a major global health challenge. Lockdown measures and social distancing sparked a global shift towards online learning, which deeply impacted universities’ daily life, and the University of Barcelona (UB) was not an exception. Accordingly, we aimed to determine the impact of the SARS-CoV-2 pandemic at the UB. To that end, we performed a cross-sectional study on a sample of 2784 UB members (n = 52,529). Participants answered a brief, ad hoc, online epidemiological questionnaire and provided a nasal swab for reverse transcription polymerase chain reaction (RT-PCR) SARS-CoV-2 analysis and a venous blood sample for SARS-CoV-2 IgG antibody assay. Total prevalence of SARS-CoV-2 infection (positive RT-PCR or positive IgG) was 14.9% (95%CI 13.3 to 17.0%). Forty-four participants (1.6%, 95%CI: 1.2–2.1%) were positive for SARS-CoV-2 RT-PCR. IgG against SARS-CoV-2 was observed in 12.8% (95%CI: 11.6–14.1%) of participants. Overall, while waiting for population vaccination and/or increased herd immunity, we should concentrate on identifying and isolating new cases and their contacts.

scholarly journals How Does the Cause of Infantile Hemiparesis Influence Other Conditioning Factors? A Preliminary Study in a Spanish Population

Children ◽  
2021 ◽  
Vol 8 (5) ◽  
pp. 323
Author(s):  
Rocío Palomo-Carrión ◽  
Rita Pilar Romero-Galisteo ◽  
Helena Romay-Barrero ◽  
Inés Martínez-Galán ◽  
Cristina Lirio-Romero ◽  
...  
Keyword(s):  
Ad Hoc ◽  
Cross Sectional Study ◽  
Motor Dysfunction ◽  
Sensory Loss ◽  
Speech Impairments ◽  
Cross Sectional ◽  
Conditioning Factors ◽  
Age Of Diagnosis ◽  
The Mean ◽  
Preliminary Study

Infantile hemiparesis may be associated with significant morbidity and may have a profound impact on a child’s physical and social development. Infantile hemiparesis is associated with motor dysfunction as well as additional neurologic impairments, including sensory loss, mental retardation, epilepsy, and vision, hearing, or speech impairments. The objective of this study was to analyze the association between the cause of infantile hemiparesis and birth (gestational age), age of diagnosis, and associated disorders present in children with infantile hemiparesis aged 0 to 3 years. An observational and cross-sectional study was performed. A simple and anonymous questionnaire was created ad hoc for parents of children diagnosed with infantile hemiparesis aged between 0 and 3 years about the situation regarding the diagnosis of hemiparesis, birth, cause of hemiparesis, and presence of other associated disorders. Perinatal stroke (60.1%) was the most common cause of hemiparesis, and the most typical associated disorder was epilepsy (34.2%), with the second largest percentage in this dimension corresponding to an absence of associated disorders (20.7%). The most frequent birth was “no premature” (74.1%). The mean age of diagnosis of infantile hemiparesis was registered at 8 months (IQR: 0–36). Knowing the possible association between different conditioning factors and the cause of infantile hemiparesis facilitates the prevention of severe sequelae in children and family, implementing an early comprehensive therapeutic approach in children with infantile hemiparesis.

scholarly journals Coverage of intermittent preventive treatment of malaria in pregnancy in four sub-Saharan countries: findings from household surveys

2020 ◽  
Author(s):  
Clara Pons-Duran ◽  
Mireia Llach ◽  
Charfudin Sacoor ◽  
Sergi Sanz ◽  
Eusebio Macete ◽  
...  
Keyword(s):  
Antenatal Care ◽  
Intermittent Preventive Treatment ◽  
Preventive Treatment ◽  
Malaria Prevention ◽  
Reproductive Age ◽  
Cluster Sampling ◽  
Household Surveys ◽  
Cross Sectional ◽  
Sub Saharan ◽  
In Pregnancy

Abstract Background Intermittent preventive treatment in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) is a key malaria prevention strategy in areas with moderate to high transmission. As part of the TIPTOP (Transforming IPT for Optimal Pregnancy) project, baseline information about IPTp coverage was collected in eight districts from four sub-Saharan countries: Democratic Republic of Congo (DRC), Madagascar, Mozambique and Nigeria. Methods Cross-sectional household surveys were conducted using a multistage cluster sampling design to estimate the coverage of IPTp and antenatal care attendance. Eligible participants were women of reproductive age who had ended a pregnancy in the 12 months preceding the interview and who had resided in the selected household during at least the past 4 months of pregnancy. Coverage was calculated using percentages and 95% confidence intervals. Results A total of 3911 women were interviewed from March to October 2018. Coverage of at least three doses of IPTp (IPTp3+) was 22% and 24% in DRC project districts; 23% and 12% in Madagascar districts; 11% and 16% in Nigeria local government areas; and 63% and 34% in Mozambique districts. In DRC, Madagascar and Nigeria, more than two-thirds of women attending at least four antenatal care visits during pregnancy received less than three doses of IPTp. Conclusions The IPTp3+ uptake in the survey districts was far from the universal coverage. However, one of the study districts in Mozambique showed a much higher coverage of IPTp3+ than the other areas, which was also higher than the 2018 average national coverage of 41%. The reasons for the high IPTp3+ coverage in this Mozambican district are unclear and require further study.

scholarly journals Appropriateness of aspirin prescribing for primary and secondary prevention of cardiovascular disease in type 2 diabetes in different care settings

2021 ◽  
Author(s):  
Shi Ying Tan ◽  
Heather Cronin ◽  
Stephen Byrne ◽  
Adrian O’Donovan ◽  
Antoinette Tuthill
Keyword(s):  
Type 2 Diabetes ◽  
Cardiovascular Disease ◽  
Primary Care ◽  
Primary Prevention ◽  
Secondary Prevention ◽  
Shared Care ◽  
University Hospital ◽  
Cross Sectional ◽  
Prevention Of Cardiovascular Disease

Abstract Background Type 2 diabetes is associated with an increased cardiovascular risk. Use of aspirin has been shown to be of benefit for secondary prevention of cardiovascular disease in patients with type 2 diabetes; benefits in primary prevention have not been clearly proven. Aims This study aims to (a) determine if aspirin is prescribed appropriately in type 2 diabetes for primary or secondary prevention of cardiovascular disease (CVD) and (b) evaluate whether there are differences in aspirin prescribing according to where people receive their care. Design Cross-sectional study Methods The medical records of individuals with type 2 diabetes aged over 18 years and attending Elmwood Primary Care Centre and Cork University Hospital Diabetes outpatient clinics (n = 400) between February and August 2017 were reviewed. Results There were 90 individuals exclusively attending primary care and 310 persons attending shared care. Overall, 49.0% (n = 196) of those were prescribed aspirin, of whom 42.3% were using it for secondary prevention. Aspirin was used significantly more in people attending shared care (p < 0.001). About 10.8% of individuals with diabetes and CVD attending shared care met guidelines for, but were not prescribed aspirin. Conclusion A significant number of people with type 2 diabetes who should have been prescribed aspirin for secondary prevention were not receiving it at the time of study assessment. In contrast, a substantial proportion who did not meet criteria for aspirin use was prescribed it for primary prevention.

scholarly journals Could Emotional Intelligence Ability Predict Salary? A Cross-Sectional Study in a Multioccupational Sample

2021 ◽  
Vol 18 (3) ◽  
pp. 1322
Author(s):  
Martin Sanchez-Gomez ◽  
Edgar Breso ◽  
Gabriele Giorgi
Keyword(s):  
Emotional Intelligence ◽  
Interpersonal Relationships ◽  
Work Experience ◽  
Ad Hoc ◽  
Preliminary Evidence ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Repair Capacity ◽  
Relevant Variable ◽  
Correlation And Regression Analysis

The study of emotional intelligence (EI) in work environments is a trending topic. However, few studies have examined the relationship between EI and salary. Therefore, the presented research aims to analyze the influence of EI on salary using a multioccupational sample. The participants were 785 subjects aged between 18 and 58 years (M = 39.41; SD = 10.95). EI ability was measured using the Mobile Emotional Intelligence Test (MEIT), while the salary was collected together with other sociodemographic variables in a questionnaire created ad hoc. After controlling for the age, gender, social class, educational level, and work experience variables, the results of correlation and regression analysis showed that participants with higher EI and emotional-repair capacity generally have higher salary. These findings provide preliminary evidence that EI is a relevant variable in achieving career success. The ability to channel and manage emotions could help employees develop stronger interpersonal relationships, leading to higher positions and greater financial compensation.

scholarly journals The Association between Dating Apps and Alcohol Consumption in an Italian Sample of Active Users, Former Users, and Non-Users

2021 ◽  
Vol 10 (7) ◽  
pp. 249
Author(s):  
Luca Flesia ◽  
Valentina Fietta ◽  
Carlo Foresta ◽  
Merylin Monaro
Keyword(s):  
Alcohol Consumption ◽  
Alcohol Use ◽  
Ad Hoc ◽  
Multiple Logistic Regression Analysis ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Dating Apps ◽  
Regular Consumption ◽  
And Gender ◽  
The Relationship

To date, the relationship between alcohol use and dating app use has been investigated mostly in conjunction with sexual activities and in homosexual men. For this reason, the aim of this study was to explore the association between dating app use and alcohol consumption among the general population. A cross-sectional study was conducted including app users, non-users, and former users: 1278 respondents completed an online ad hoc questionnaire assessing dating app use, motivations for installing dating apps, alcohol use, and demographics. Multiple logistic regression analysis was run to investigate the association between dating app use, demographic features, and alcohol consumption. Whereas educational level, age, and gender significantly contributed to the regular consumption of alcohol, dating app use did not account for a significant amount of variance between regular and not regular drinkers. However, people who installed and used dating apps with the motivation of searching for sexual partners were more likely to be regular drinkers. Among the active users, heavy app users were less likely to drink regularly. The study indicates that underlying factors (sexual aspects, motives for using the apps) and the intensity of using the apps may mediate the relationship between dating app use and alcohol use.

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