scholarly journals Determination of Histamine in Tomatoes by Capillary Electrophoresis

2000 ◽  
Vol 83 (1) ◽  
pp. 89-94 ◽  
Author(s):  
Elek Bolygo ◽  
Paul A Cooper ◽  
K Michael Jessop ◽  
Frank Moffatt
Keyword(s):  
Capillary Electrophoresis ◽  
Signal To Noise Ratio ◽  
High Sensitivity ◽  
Flow Cell ◽  
Voltage Gradient ◽  
Signal To Noise ◽  
Tomato Fruits ◽  
Endogenous Level ◽  
Selection Of

Abstract An improved capillary electrophoresis assay for histamine in crude extracts was developed and used to determine histamine levels in a selection of tomato fruits and pastes. Performance in terms of reproducibility and sensitivity was optimized by use of a high sensitivity detector flow cell, sodium hydroxide rinses, and a voltage gradient. The method was linear down to 0.2 μg/mL (signal-to-noise ratio = 4:1), which was below the endogenous level in all samples.

Determination of the Best Emulsion for the Microscopy of Crystals

1981 ◽  
Vol 39 ◽  
pp. 32-33
Author(s):  
David A. Grano ◽  
Kenneth H. Downing
Keyword(s):  
Spatial Frequency ◽  
Information Transfer ◽  
Signal To Noise Ratio ◽  
Experimental Situation ◽  
Photographic Emulsion ◽  
Modulation Transfer ◽  
Signal To Noise ◽  
Frequency Space ◽  
Noise Ratio

The retrieval of high-resolution information from images of biological crystals depends, in part, on the use of the correct photographic emulsion. We have been investigating the information transfer properties of twelve emulsions with a view toward 1) characterizing the emulsions by a few, measurable quantities, and 2) identifying the “best” emulsion of those we have studied for use in any given experimental situation. Because our interests lie in the examination of crystalline specimens, we've chosen to evaluate an emulsion's signal-to-noise ratio (SNR) as a function of spatial frequency and use this as our critereon for determining the best emulsion.The signal-to-noise ratio in frequency space depends on several factors. First, the signal depends on the speed of the emulsion and its modulation transfer function (MTF). By procedures outlined in, MTF's have been found for all the emulsions tested and can be fit by an analytic expression 1/(1+(S/S0)2). Figure 1 shows the experimental data and fitted curve for an emulsion with a better than average MTF. A single parameter, the spatial frequency at which the transfer falls to 50% (S0), characterizes this curve.

scholarly journals The Double Face of Ketamine—The Possibility of Its Identification in Blood and Beverages

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 813
Author(s):  
Magdalena Świądro ◽  
Paweł Stelmaszczyk ◽  
Irena Lenart ◽  
Renata Wietecha-Posłuszny
Keyword(s):  
Date Rape ◽  
Signal To Noise Ratio ◽  
High Sensitivity ◽  
Heroin Addiction ◽  
Assisted Extraction ◽  
Low Concentrations ◽  
High Concentrations ◽  
Rosé Wine ◽  
Tof Ms

The purpose of this study was to develop and validate a high-sensitivity methodology for identifying one of the most used drugs—ketamine. Ketamine is used medicinally to treat depression, alcoholism, and heroin addiction. Moreover, ketamine is the main ingredient used in so-called “date-rape” pills (DRP). This study presents a novel methodology for the simultaneous determination of ketamine based on the Dried Blood Spot (DBS) method, in combination with capillary electrophoresis coupled with a mass spectrometer (CE-TOF-MS). Then, 6-mm circles were punched out from DBS collected on Whatman DMPK-C paper and extracted using microwave-assisted extraction (MAE). The assay was linear in the range of 25–300 ng/mL. Values of limits of detection (LOD = 6.0 ng/mL) and quantification (LOQ = 19.8 ng/mL) were determined based on the signal to noise ratio. Intra-day precision at each determined concentration level was in the range of 6.1–11.1%, and inter-day between 7.9–13.1%. The obtained precision was under 15.0% (for medium and high concentrations) and lower than 20.0% (for low concentrations), which are in accordance with acceptance criteria. Therefore, the DBS/MAE/CE-TOF-MS method was successfully checked for analysis of ketamine in matrices other than blood, i.e., rose wine and orange juice. Moreover, it is possible to identify ketamine in the presence of flunitrazepam, which is the other most popular ingredient used in DRP. Based on this information, the selectivity of the proposed methodology for identifying ketamine in the presence of other components of rape pills was checked.

scholarly journals Collecting Microplastics in Gardens: Case Study (i) of Soil

2021 ◽  
Vol 9 ◽  
Author(s):  
Zahra Sobhani ◽  
Yunlong Luo ◽  
Christopher T. Gibson ◽  
Youhong Tang ◽  
Ravi Naidu ◽  
...  
Keyword(s):  
Signal To Noise Ratio ◽  
Point Of View ◽  
Signal To Noise ◽  
Statistical Point ◽  
Image Mapping ◽  
Noise Ratio ◽  
In The Beginning ◽  
Raman Image ◽  
Selection Of

As an emerging contaminant, microplastic is receiving increasing attention. However, the contamination source is not fully known, and new sources are still being identified. Herewith, we report that microplastics can be found in our gardens, either due to the wrongdoing of leaving plastic bubble wraps to be mixed with mulches or due to the use of plastic landscape fabrics in the mulch bed. In the beginning, they were of large sizes, such as > 5 mm. However, after 7 years in the garden, owing to natural degradation, weathering, or abrasion, microplastics are released. We categorize the plastic fragments into different groups, 5 mm–0.75 mm, 0.75 mm–100 μm, and 100–0.8 μm, using filters such as kitchenware, meaning we can collect microplastics in our gardens by ourselves. We then characterized the plastics using Raman image mapping and a logic-based algorithm to increase the signal-to-noise ratio and the image certainty. This is because the signal-to-noise ratio from a single Raman spectrum, or even from an individual peak, is significantly less than that from a spectrum matrix of Raman mapping (such as 1 vs. 50 × 50) that contains 2,500 spectra, from the statistical point of view. From the 10 g soil we sampled, we could detect the microplastics, including large (5 mm–100 μm) fragments and small (<100 μm) ones, suggesting the degradation fate of plastics in the gardens. Overall, these results warn us that we must be careful when we do gardening, including selection of plastic items for gardens.

scholarly journals Distance scaling method for accurate prediction of slowly varying magnetic fields in satellite missions

2016 ◽  
Vol 5 (2) ◽  
pp. 281-288 ◽  
Author(s):  
Panagiotis P. Zacharias ◽  
Elpida G. Chatzineofytou ◽  
Sotirios T. Spantideas ◽  
Christos N. Capsalis
Keyword(s):  
Signal To Noise Ratio ◽  
Near Field ◽  
Magnetic Behavior ◽  
Field Measurements ◽  
High Signal ◽  
Signal To Noise ◽  
Scaling Method ◽  
Magnetic Signature ◽  
The Magnetic Field

Abstract. In the present work, the determination of the magnetic behavior of localized magnetic sources from near-field measurements is examined. The distance power law of the magnetic field fall-off is used in various cases to accurately predict the magnetic signature of an equipment under test (EUT) consisting of multiple alternating current (AC) magnetic sources. Therefore, parameters concerning the location of the observation points (magnetometers) are studied towards this scope. The results clearly show that these parameters are independent of the EUT's size and layout. Additionally, the techniques developed in the present study enable the placing of the magnetometers close to the EUT, thus achieving high signal-to-noise ratio (SNR). Finally, the proposed method is verified by real measurements, using a mobile phone as an EUT.

scholarly journals High-Sensitivity Large-Area Photodiode Read-Out Using a Divide-and-Conquer Technique

Sensors ◽  
2020 ◽  
Vol 20 (21) ◽  
pp. 6316
Author(s):  
Guillermo Royo ◽  
Carlos Sánchez-Azqueta ◽  
Concepción Aldea ◽  
Santiago Celma
Keyword(s):  
Traditional Approach ◽  
Signal To Noise Ratio ◽  
High Sensitivity ◽  
Divide And Conquer ◽  
Transimpedance Amplifier ◽  
Large Area ◽  
Signal To Noise ◽  
Remarkable Improvement ◽  
The Core ◽  
Novel Technique

In this letter, we present a novel technique to increase the sensitivity of optical read-out with large integrated photodiodes (PD). It consists of manufacturing the PD in several pieces, instead of a single device, and connecting a dedicated transimpedance amplifier (TIA) to each of these pieces. The output signals of the TIAs are combined, achieving a higher signal-to-noise ratio than with the traditional approach. This work shows a remarkable improvement in the sensitivity and transimpedance without the need for additional modifications or compensation techniques. As a result, an increase in sensitivity of 7.9 dBm and transimpedance of 8.7 dBΩ for the same bandwidth is achieved when dividing the photodiode read-out into 16 parallel paths. The proposed divide-and-conquer technique can be applied to any TIA design, and it is also independent of the core amplifier structure and fabrication process, which means it is compatible with every technology allowing the integration of PDs.

A Carbon-Based DNA Framework Nano–Bio Interface for Biosensing with High Sensitivity and a High Signal-to-Noise Ratio

ACS Sensors ◽  
2020 ◽  
Vol 5 (12) ◽  
pp. 3979-3987
Author(s):  
Jing Su ◽  
Wenhan Liu ◽  
Shixing Chen ◽  
Wangping Deng ◽  
Yanzhi Dou ◽  
...  
Keyword(s):  
Signal To Noise Ratio ◽  
High Sensitivity ◽  
High Signal ◽  
Signal To Noise ◽  
Noise Ratio ◽  
Carbon Based

Performance Data of a New 2048 X 2048 Pixel Slow-Scan CCD Camera For TEM

2000 ◽  
Vol 6 (S2) ◽  
pp. 732-733
Author(s):  
S.A. Hiller ◽  
B. Kabius ◽  
W. Probst ◽  
H. Tröster ◽  
M. Trendelenburg ◽  
...  
Keyword(s):  
Low Dose ◽  
Signal To Noise Ratio ◽  
Ccd Camera ◽  
High Sensitivity ◽  
Signal To Noise ◽  
Ideal Image ◽  
Main Disadvantage ◽  
Ccd Arrays ◽  
Holographic Reconstruction ◽  
The Ideal

Excellent linearity and high sensitivity have made SSCs the ideal image detector for almost every TEM application. Their ability to make high quality digital images available within fraction of seconds for further evaluation and processing in a PC, have made them a non-dispensable accessory for any modern TEM. However, despite their excellent characteristics, SSCs provide a restricted number of individual image points in respect to a negative, what is considered to be the main disadvantage of this detector. To compensate for this, CCDs with 2048x2048 pixel are available since some time. SSCs using these 2kx2k CCD arrays not only provide 4 times the pixel number but also offer a lot more options people have waiting for: e. g. highly resolved low-dose or ESI images with significantly improved signal to noise ratio, or higher resolved images for diffraction analysis and holographic reconstruction.

Sign in / Sign up

Export Citation Format

Share Document