scholarly journals Quality assessment and antioxidant activities of the blossoms of Inula nervosa Wall

Author(s):  
Li-xia Hu ◽  
Mei-feng Luo ◽  
Wen-jing Guo ◽  
Xiao He ◽  
Jun Zhou ◽  
...  

Abstract Background Currently, although Inula nervosa Wall is well investigated, little is understood about blossoms of Inula nervosa Wall (BINW). Objective In this work, we systematically investigated the antioxidant activity of the extract from BINW by various standard assays including DPPH free radical ability, ABTS• +, and FRAP. Methods Chemical compounds are tentatively identified through an UHPLC-QTOF-MS system. Furthermore, the contents of nine compounds were detected with UHPLC method coupled with PDA. By carefully analyzing the quantitative data via clusters analysis and PCA. Results 46 compounds are tentatively identified and our results showed that 9 compound samples in 21 batches of BINW collected from different areas could be differentiated and analyzed by a heatmap visualization. In addition, the contents of nine compounds (flavonoids, phenolic acids) exhibited a total of higher amounts and better antioxidant activities from Yunnan than those from other three origins. Conclusions Our study not only developed a powerful platform to explain the difference traditional Chinese medicines (TCMs) species that in closely related through the chemometric and chemical profiling, but also presented a useful method to establish quality criteria of BINW with multiple origins. Highlights To detailly characterize the BINW, we not only performed DPPH, FRAP and ABTS assays to investigate its antioxidant activity, but also established UHPLC-QTOF-MS/MS and UHPLC-PDA based methods to comprehensively identify and qualitatively analyze its components.

RSC Advances ◽  
2018 ◽  
Vol 8 (49) ◽  
pp. 27661-27673 ◽  
Author(s):  
Yujing Zhang ◽  
Chao Wang ◽  
Fangliang Yang ◽  
Zhe Yang ◽  
Fangren Wang ◽  
...  

Traditional Chinese medicines (TCM)/herbal medicines (HM) are too complicated to comprehensively investigate their quality consistency effectively with a single detection technique.


2022 ◽  
Vol 2022 ◽  
pp. 1-13
Author(s):  
Didi Ma ◽  
Jue Wang ◽  
Guo Yin ◽  
Lijun Wang ◽  
Yibao Jin ◽  
...  

Panax notoginseng (PN) is one of the most valuable traditional Chinese medicines and has extensive pharmacological effects. Recent studies demonstrated that PN exhibited pharmacological effect related to Alzheimer’s disease (AD). However, whether steaming process can boost its anti-AD activity is still unexplored. To fill this gap, effects of steaming durations and temperatures on the chemical characterization, neuroprotective and antioxidant activities of PN were systematically investigated in this study. HPLC fingerprint coupled with quantitative analysis demonstrated striking conversion of original saponins to less polar ones with the increase in the steaming time and temperature. In the viewpoint of anti-AD activity on neuroprotective and antioxidant effects, several steamed PN samples (110°C-6/8/10 h, 120°C ‐4/6 h samples) displayed a significant increase both in cell viability and oxygen radical absorption capacity (ORAC) values compared with the no steamed one ( P < 0.01 or P < 0.005 ). Steaming temperature had the greater impact on the change of chemical composition and anti-AD activity of PN. Moreover, the spectrum-effect relationship analysis revealed that the transformed saponins were partially responsible for the increased neuroprotective and antioxidant effects of steamed PN. Therefore, steamed PN could be used as a potential crude drug for prevention and treatment of AD.


RSC Advances ◽  
2016 ◽  
Vol 6 (90) ◽  
pp. 87616-87627 ◽  
Author(s):  
Lanping Yang ◽  
Xiuman Xie ◽  
Liu Yang ◽  
Jing Zhang ◽  
Guoxiang Sun

Traditional Chinese medicines/herbal medicines (TCM/HM) are too complicated mixture systems to investigate their quality consistency effectively using a single detection technique.


2019 ◽  
Vol 1 (02) ◽  
pp. 60-63
Author(s):  
Novi Fajar Utami ◽  
Nhadira Nhestricia

The content of robusta coffee include alkaloids, flavonoids, saponin, tannins, caffeine, and phenol. Differences in the method of extraction of a plant can cause differences in the number of chemical compounds. The purpose of this study was to determine the phytochemical characteristics and antioxidant activity in robusta coffee beans extracted by maceration and sonication method. Antioxidant activity was performed by the method of DPPH (2,2-diphenyl-1-picrylhydrazyl) by spectrophotometry. The results showed that phytochemical characteristics of robusta coffee extract of maceration and sonication contain the same chemical compounds, namely alkaloids, flavonoids, tannins, and saponins. The antioxidant activity of robusta coffee seed extract of sonication result has IC50 of 54,14 ppm which is better than the extract of robusta coffee beans from maceration.


2015 ◽  
Vol 9 (48) ◽  
pp. 1131-1138 ◽  
Author(s):  
Hsieh Ting Fang ◽  
Chang Yaw Nan ◽  
Liu Bing Lan ◽  
Hsieh Ting Fang ◽  
Chang Yaw Nan ◽  
...  

2021 ◽  
Vol 15 (01) ◽  
pp. 34
Author(s):  
Ade Galuh Rakhmadevi ◽  
Maria 'Azizah ◽  
Anna Mardiana Handayani

Kersen trees (Muntingia calabura L.) are included in the Elaeocarpaceae family and are mostly used as a protective tree. The kersen leaves were an environmental waste (trash) and still lacks implementation in food processing. This study was aimed to determine the chemical characteristics and antioxidant activity of kersen leaves at different altitudes and their potential as an herbal tea. The difference in the height of the place to grow will be used as a factor to be studied so that this study uses a completely randomized design with a one factor pattern (height the place of growings). Kersen leaves were taken from three districts, namely Jember (83 amsl/above mean sea level), Situbondo (5 amsl), and Bondowoso (255 amsl). The results showed that the chemical characteristics of kersen leaves consisting of moisture content, ash content, fat content, and carbohydrate content were not significantly different between regions, while protein content and antioxidant activity levels were significantly different between regions. Keywords: antioxidant activities, kersen leaves


2021 ◽  
Vol 12 ◽  
Author(s):  
Li Wu ◽  
Kangxi Zhou ◽  
Feng Chen ◽  
Guimei Chen ◽  
Ying Yu ◽  
...  

Graphical AbstractMonascus yellow pigments (MYPs) in functional Qu (FQ) have a higher antioxidant potential than those in coloring Qu (CQ). The difference in antioxidant activities of MYPs is due to the critical hydroxyl group on C-3′ or C-11.


2018 ◽  
Vol 2018 ◽  
pp. 1-12 ◽  
Author(s):  
Fu Wang ◽  
Lin Chen ◽  
Feng-qing Li ◽  
Su-juan Liu ◽  
Hong-ping Chen ◽  
...  

There are thousands of traditional Chinese medicines in China, and they all have to be stored for a period of time for the reason of market price or other factors. But some traditional Chinese medicines especially need to be stored longer, and the clinical efficacy will be better. The cause and mechanism of this phenomenon have attracted much attention in recent years. In this study, we analyze the reason of “the longer storage period the better” of Pericarpium Citri Reticulatae (PCR); method of microscopic and molecular identification was used to identify the fungi separated and purified from PCR. The HPLC and UV spectrophotometry methods were used to determine the contents of flavonoids in PCR. The isolated fungi were inoculated into sterile samples to screen the fungi closely related to the change of flavonoids. The results indicate that the strain ofAspergillus nigercould obviously promote the contents of flavonoids, and it could also increase the antioxidant effect of PCR. In conclusion, this study explains the reason of “the longer storage period the better” of PCR from the perspective of microbe, proving the beneficial effect of microorganism on the surface of PCR.


Sign in / Sign up

Export Citation Format

Share Document