scholarly journals 179 Efficacy and safety of amino acids with biomass for growth and health of newly-weaned pigs

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 77-77
Author(s):  
Yi-Chi Cheng ◽  
Marcos E Duarte ◽  
Sung Woo Kim
Keyword(s):  
Amino Acids ◽  
Growth Performance ◽  
Function Analysis ◽  
Basal Diet ◽  
Jejunal Mucosa ◽  
Phase 2 ◽  
Efficacy And Safety ◽  
Gut Health ◽  
Weaned Pigs ◽  
Dietary Treatments

Abstract The objective was to test the efficacy of L-Thr or L-Val with biomass (ThrPro or ValPro; CJ BIO, Fort Dodge, IA) on growth performance and health compared with L-Thr or L-Val (purified) in newly-weaned pigs. There were 9 dietary treatments based on NRC (2012) requirements: NC (basal diet meeting 70% of requirements for SID Thr and Val); 4 treatments based on basal diet meeting 95% of requirements: LT (with L-Thr), LV (with L-Val), PT (with ThrPro), and PV (with ValPro); HLT (fivefold L-Thr in LT), HLV (fivefold L-Val in LV), HPT (fivefold ThrPro in PT), and HPV (fivefold ValPro in PV). Pigs were fed for 26 d in 2 phases. Feed intake and BW were measured at d 0, 5, 10, 17, and 26. Blood was collected on d 21 for liver function analysis. Pigs were euthanized on d 26 to collect jejunal mucosa for gut health parameters. Data were analyzed by SAS using MIXED procedure. Pigs fed LT and LV or PT and PV had higher (P < 0.05) ADG than pigs fed NC during phase 2. Pigs fed LT, LV, PT, and PV had higher ADFI and G:F than pigs fed NC during d 17 to 26. Pigs fed PT and PV had lower (P < 0.05) G:F than pigs fed HPT and HPV during phase 2. Pigs fed LT and LV or PT and PV had lower (P < 0.05) BUN than pigs fed NC. Overall, pigs fed PT and PV had no differences in any analyzed measurements from pigs fed LT and LV and pigs fed HPT and HPV. In conclusion, PT and PV were equally efficient to LT and LV for growth performance and health. HPT and HPV did not impair liver and gut health compared with PT and PV.

scholarly journals 173 Lysed Corynebacterium glutamicum cell mass from lysine production as a novel feed additive to enhance gut health and growth of newly-weaned pigs

2020 ◽  
Vol 98 (Supplement_3) ◽  
pp. 77-78
Author(s):  
Yi-Chi Cheng ◽  
Marcos E Duarte ◽  
Sung Woo Kim
Keyword(s):  
Growth Performance ◽  
Corynebacterium Glutamicum ◽  
Block Design ◽  
Cell Mass ◽  
Nutrient Digestibility ◽  
Feed Additive ◽  
Jejunal Mucosa ◽  
Gut Health ◽  
Weaned Pigs ◽  
Dietary Treatments

Abstract The objective was to determine the functional and nutritional values of Corynebacterium glutamicum Cell Mass (CGCM) on growth performance and gut health of newly-weaned pigs. Forty newly-weaned pigs (21 d of age; initial BW 7.1 ± 0.4 kg) were allotted to 5 dietary treatments based on randomized complete block design with sex and BW as blocks. The lysine broth of CGCM (CJ Bio, Fort Dodge, IA) was homogenized by using French press and dried to obtain lysed CGCM. Dietary treatments were: basal diet with lysed CGCM at 0, 0.7, 1.4, 2.1%, and with 1.4% intact CGCM. Experimental diets were formulated based on nutrient requirements (NRC, 2012) and pigs were fed based on 2 phases (10 and 11 d for each phase). Titanium dioxide (0.4%) was added to phase 2 diets as an indigestible external marker to calculate nutrient digestibility. Feed intake and BW were measured at d 0, 10, and 21. Pigs were euthanized on d 21 to collect proximal and distal jejunal mucosa to measure TNF-α, IL-8, MDA, IgA, and IgG concentrations. Diets and ileal digesta were collected to measure AID. Data were analyzed by SAS using MIXED, REG, and GLM procedures. Overall, increasing daily lysed CGCM intake increased (P < 0.05) ADG (211 to 296 g) and ADFI (432 to 501 g). Increasing levels of lysed CGCM decreased (P < 0.05) MDA and changed (quadratic, P < 0.05) IgA (max: 4.90 ng/mg at 1.13%) and IgG (max: 3.37 ng/mg at 1.04%) in the proximal jejunal mucosa. Increasing daily lysed CGCM intake had quadratic effect (P< 0.05) of protein carbonyl (max: 6.3 μmol/mg at 4.9 g/d). Lysed CGCM potentially benefits growth performance and gut health of newly-weaned pigs by reducing oxidative stress and increasing immune response.

scholarly journals Probiotics and Achyranthes bidentata Polysaccharides Improve Growth Performance via Promoting Intestinal Nutrient Utilization and Enhancing Immune Function of Weaned Pigs

Animals ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 2617
Author(s):  
Gaifeng Hou ◽  
Wei Peng ◽  
Liangkai Wei ◽  
Rui Li ◽  
Xingguo Huang ◽  
...  
Keyword(s):  
Immune Function ◽  
Growth Performance ◽  
Basal Diet ◽  
Nutrient Utilization ◽  
Jejunal Mucosa ◽  
Weaned Pigs ◽  
Achyranthes Bidentata ◽  
Dietary Treatments ◽  
Positive Effect ◽  
Nutrients Digestibility

The experiment aimed to investigate the effects of probiotics and Achyranthes bidentata polysaccharides on the growth performance, nutrients digestibility, and immune function of weaned pigs. One hundred and twenty weaned pigs (about 7 kg BW, 23 ± 2 d) were allotted to five dietary treatments (CON: antibiotics-free basal diet; ANT: CON + antibiotics; PRO: CON + probiotics; ABPS: CON + Achyranthes bidentata polysaccharides; P-ABPS: PRO + ABPS) for a 28-day trial. Compared with CON, pigs in ANT, PRO, ABPS, and P-ABPS had greater (p < 0.05) ADG, ATTD of CP and GE, serum ALB, IgA and IL-2, duodenal intraepithelial lymphocyte, ileal VH and jejunal mucosa sIgA, but lower (p < 0.05) fecal scores, serum BUN, and IL-1β. Meanwhile, ANT, PRO, ABPS, and P-ABPS exhibited similar beneficial roles on growth performance, nutrients digestibility, serum parameters, and immune function. Interestingly, P-ABPS effects were similar to those obtained with ANT rather than with PRO or ABPS. In conclusion, Dietary PRO or ABPS used alone or in combination (P-ABPS), the combination augmenting the positive effect more than the independent supplement, could improve piglets’ growth performance via promoting intestinal nutrient digestion and absorption and enhancing immune function, indicating it had the potential to act as an alternative to in-feed antibiotics used in piglet diets.

187 Effects of Oligosaccharide-based Polymer on Growth Performance, Diarrhea, and Fecal β-hemolytic Coliforms in Weanling Pigs Experimentally Infected with a Pathogenic E. coli

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 90-90
Author(s):  
Kwangwook Kim ◽  
Yijie He ◽  
Cynthia Jinno ◽  
Seijoo Yang ◽  
Xunde Li ◽  
...  
Keyword(s):  
Growth Performance ◽  
Feed Efficiency ◽  
Basal Diet ◽  
Watery Diarrhea ◽  
Experimental Unit ◽  
Post Inoculation ◽  
Weaned Pigs ◽  
E Coli ◽  
Diet Control ◽  
Dietary Treatments

Abstract The objective of this experiment was to investigate dietary supplementation of oligosaccharide-based polymer on growth performance, diarrhea, and fecal β-hemolytic coliforms of weaned pigs experimentally infected with a pathogenic F18 Escherichia coli (E. coli). Forty-eight pigs (7.23 ± 1.11 kg BW) were individually housed in disease containment rooms and randomly allotted to one of four treatments with 12 replicate pigs per treatment. The four dietary treatments were a nursery basal diet (control), and 3 additional diets supplemented with 50 mg/kg Mecadox (AGP), 10 or 20 mg/kg of oligosaccharide-based polymer. The experiment lasted 18 d [7 d before and 11 d after the first inoculation (d 0)]. The doses of F18 E. coli inoculum were 1010 cfu/3 mL oral dose daily for 3 days. Growth performance was measured on d -7 to 0 before inoculation, and d 0 to 5 and 5 to 11 post-inoculation (PI). Diarrhea score (DS; 1, normal, to 5, watery diarrhea) was daily recorded for each pig. Fecal samples were collected on d 2, 5, 8, and 11 PI to test the percentage of β-hemolytic coliforms in total coliforms. All data were analyzed by ANOVA using the PROC MIXED of SAS with pig as the experimental unit. Inclusion of oligosaccharide-based polymer linearly increased (P &lt; 0.05) ADFI on d 0 to 5 PI, and feed efficiency on d 0 to 5 PI and d 5 to 11 PI (P = 0.07), compared with the control. Supplementation of AGP or oligosaccharide-based polymer reduced (P &lt; 0.01) frequency of diarrhea of pigs from d 0 to 11 PI. No differences were observed in overall growth performance and percentage of fecal β-hemolytic coliforms on d 8 PI among pigs in AGP and oligosaccharide-based polymer treatments. In conclusion, supplementation of oligosaccharide-based polymer enhanced feed efficiency and reduced diarrhea of weaned pigs infected with a pathogenic E. coli.

scholarly journals Growth performance and gut health of Escherichia coli-challenged weaned pigs fed diets supplemented with a Bacillus subtilis direct-fed microbial

2020 ◽  
Vol 4 (3) ◽  
Author(s):  
Sangwoo Park ◽  
Jung Wook Lee ◽  
Kevin Jerez Bogota ◽  
David Francis ◽  
Jolie Caroline González-Vega ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Bacillus Subtilis ◽  
Growth Performance ◽  
Feed Efficiency ◽  
Basal Diet ◽  
Feed Additives ◽  
Growth Promoter ◽  
Gut Health ◽  
Weaned Pigs ◽  
E Coli

Abstract This study was conducted to investigate the effects of a direct-fed microbial (DFM) product (Bacillus subtilis strain DSM 32540) in weaned pigs challenged with K88 strain of Escherichia coli on growth performance and indicators of gut health. A total of 21 weaned pigs [initial body weight (BW) = 8.19 kg] were housed individually in pens and fed three diets (seven replicates per diet) for 21 d in a completely randomized design. The three diets were a corn-soybean meal-based basal diet without feed additives, a basal diet with 0.25% antibiotics (neo-Oxy 10-10; neomycin + oxytetracycline), or a basal diet with 0.05% DFM. All pigs were orally challenged with a subclinical dose (6.7 × 108 CFU/mL) of K88 strain of E. coli on day 3 of the study (3 d after weaning). Feed intake and BW data were collected on days 0, 3, 7, 14, and 21. Fecal scores were recorded daily. On day 21, pigs were sacrificed to determine various indicators of gut health. Supplementation of the basal diet with antibiotics or DFM did not affect the overall (days 0–21) growth performance of pigs. However, antibiotics or DFM supplementation increased (P = 0.010) gain:feed (G:F) of pigs during the post-E. coli challenge period (days 3–21) by 23% and 24%, respectively. The G:F for the DFM-supplemented diet did not differ from that for the antibiotics-supplemented diet. The frequency of diarrhea for pigs fed a diet with antibiotics or DFM tended to be lower (P = 0.071) than that of pigs fed the basal diet. The jejunal villous height (VH) and the VH to crypt depth ratio (VH:CD) were increased (P &lt; 0.001) by 33% and 35%, respectively, due to the inclusion of antibiotics in the basal diet and by 43% and 41%, respectively due to the inclusion of DFM in the basal diet. The VH and VH:CD for the DFM-supplemented diet were greater (P &lt; 0.05) than those for the antibiotics-supplemented diet. Ileal VH was increased (P &lt; 0.05) by 46% due to the inclusion of DFM in the basal diet. The empty weight of small intestine, cecum, or colon relative to live BW was unaffected by dietary antibiotics or DFM supplementation. In conclusion, the addition of DFM to the basal diet improved the feed efficiency of E. coli-challenged weaned pigs to a value similar to that of the antibiotics-supplemented diet and increased jejunal VH and VH:CD ratio to values greater than those for the antibiotics-supplemented diet. Thus, under E. coli challenge, the test DFM product may replace the use of antibiotics as a growth promoter in diets for weaned pigs to improve feed efficiency and gut integrity.

scholarly journals 15 Dietary supplementation with lactic acid and glutamine improve intestinal digestive and regulate intestinal microflora in weaning piglets

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 16-16
Author(s):  
Ping Zheng ◽  
Junjie Jiang ◽  
Bing Yu ◽  
Jun He ◽  
Jie Yu ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Growth Performance ◽  
Basal Diet ◽  
Jejunal Mucosa ◽  
Mrna Levels ◽  
Intestinal Development ◽  
Serum Growth Hormone ◽  
Weaning Piglets ◽  
Dietary Treatments

Abstract This study aimed to evaluate the effects of dietary addition of lactic acid and glutamine on growth performance and intestinal health in weaning pigs. Ninety six 24-d-old piglets (Duroc × Landrace × Yorkshire) with BW of 7.24± 0.09 kg were randomly assigned to 1 of 4 dietary treatments: 1) basal diet (CON), 2) CON supplemented with 2% lactic acid (LS), 3) CON supplemented with 1% glutamine (GS), and 4) CON supplemented with 2% lactic acid and 1% glutamine (LGS). After 28-d trial, 6 piglets from each treatment were randomly selected to collect serum and intestinal samples. The results showed that piglets fed the LGS had a greater (P &lt; 0.05) ADG than piglets fed the CON diet. Compared with CON, apparent total tract digestibility of CP in LS, GS and LGS was greater (P &lt; 0.05), index of diarrhea in LS and LGS was lower (P &lt; 0.05), serum IGF-1 in LS, GS and LGS and serum growth hormone in LS and GS were improved (P &lt; 0.05). Furthermore, jejunal villus height in LS and LGS were increased (P &lt; 0.05), the activities of amylase and lipase of the jejunal mucosa in LS and LGS were increased (P &lt; 0.05). In addition, compared with CON, pigs fed the LS, GS and LGS up-regulated (P &lt; 0.05) the mRNA levels of glucose transport type 2, IGF-1, occludin. Moreover, LGS had higher (P &lt; 0.05) abundances of total bacteria, Lactobacillus and Bifidobacterium in cecal and colonic digesta, and higher concentrations of total volatile fatty acid in cecal digesta. Collectively, the current results indicate that dietary addition of lactic acid and glutamine combination could improve growth performance through the promotion of the small intestinal development, increasing digestive, and regulating balances of microflora in piglets.

scholarly journals Impact of feeding fermentable proteins and carbohydrates on growth performance, gut health and gastrointestinal function of newly weaned pigs

2008 ◽  
Vol 88 (2) ◽  
pp. 271-281 ◽  
Author(s):  
E. A. Jeaurond ◽  
M. Rademacher ◽  
J. R. Pluske ◽  
C. H. Zhu ◽  
C. F. M. de Lange
Keyword(s):  
Growth Performance ◽  
Negative Impact ◽  
Average Daily Gain ◽  
Basal Diet ◽  
Ammonia Concentration ◽  
Interactive Effects ◽  
Gastrointestinal Function ◽  
Gut Health ◽  
Weaned Pigs ◽  
Enteric Fermentation

Feeding fermentable carbohydrates (FC) to weanling pigs may reduce the negative impact of proteolytic fermentation on gastrointestinal health and function. A total of 144 newly weaned pigs [6.23 kg body weight (BW); six pens per treatment; six pigs per pen) were used to determine the interactive effects of feeding additional fermentable protein (FP) and FC on growth performance, gastrointestinal function and intestinal health. Dietary treatments, based on a 2 × 2 factorial arrangement, were: (1) basal diet (control); (2) control + 10% poultry meal (PM) as FP source; (3) control + 5% beet pulp (BP) as FC source; and (4) control + 10% PM and 5% BP. Diets were formulated to be similar in digestible energy (DE) and digestible amino acid contents. In general, no interactive effects of FC and FP were observed (P > 0.10). During the 3-wk post-weaning period, feeding FP reduced average daily gain (ADG) (242 vs. 269 g d-1; P < 0.05), while FC increased ADG (269 vs. 243 g d-1; P < 0.05). Overall, feed intake did not differ between treatments (P > 0.10). On days 14 and 28 post-weaning, Clostridia spp. counts in colon contents, counts of white cells and segmented neutrophils in blood were lowered (P < 0.05) by feeding FC. Blood urea nitrogen was increased by feeding FP (9.5 vs. 6.5 mg dL-1; P < 0.05), while ammonia concentration in colon contents was lowered by FC (154 vs. 193 µg mL-1) (P = 0.06). Among biogenic amines, levels of tyramine (140 vs. 304 nmol g-1 DM) and spermidine (174 vs. 219 nmol g-1 DM) in colon contents were lowered (P < 0.05) by FC. Acetic, proprionic and butyric acid contents in colon contents were increased by feeding FC, while valeric and caproic acid content decreased by feeding FP (P < 0.05). Feeding FC and FP had no effect (P > 0.10) on colon histology, pH, fecal consistency score and organ weights. Results suggest that FP and FC have independent effects on newly weaned pigs, while effects appear partly related to changes in gut microbiota. Key words: Enteric fermentation, fiber, gastrointestinal function, protein, pigs

scholarly journals Dietary Bacillus spp. enhanced growth and disease resistance of weaned pigs by modulating intestinal microbiota and systemic immunity

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Yijie He ◽  
Cynthia Jinno ◽  
Kwangwook Kim ◽  
Zhaohai Wu ◽  
Bie Tan ◽  
...  
Keyword(s):  
Gene Expression ◽  
Bacillus Subtilis ◽  
Growth Performance ◽  
Systemic Inflammation ◽  
Bacillus Pumilus ◽  
Jejunal Mucosa ◽  
Gut Health ◽  
Weaned Pigs ◽  
Ileal Mucosa ◽  
Systemic Immunity

Abstract Background Previous research has shown that dietary supplementation of Bacillus spp. probiotics exerts beneficial effects on animals’ growth. However, limited studies have evaluated the efficacy of Bacillus spp. on weaned pigs and their effects on host gut health and microbiome, and systemic immunity using a disease challenge model. The objective of this experiment was to investigate the effects of two Bacillus spp. strains (Bacillus subtilis DSM 32540 and Bacillus pumilus DSM 32539) on growth performance, diarrhea, intestinal health, microbiome, and systemic immunity of weaned pigs experimentally infected with an enterotoxigenic Escherichia coli (ETEC). Results Pigs in PRO1 (Bacillus subtilis DSM 32540) had greater (P < 0.05) body weight on d 7 and 14 PI, greater (P < 0.05) ADG from d 0 to 7 and d 7 to 14 PI, compared with pigs in CON (Control). Pigs in PRO1 had milder (P < 0.05) diarrhea on d 2 and 3 PI compared with pigs in CON. However, no differences were observed in growth performance and diarrhea score between PRO2 (Bacillus pumilus DSM 32539) and CON groups. Supplementation of PRO1 decreased (P < 0.05) lymphocyte counts on d 7 and 14 PI, compared with CON. Supplementation of PRO1 and PRO2 both reduced (P < 0.05) total coliforms in mesenteric lymph nodes on d 21 PI. Pigs in PRO2 had greater (P < 0.05) goblet cell number and sulfomucin percentage in duodenal villi and greater (P < 0.05) sialomucin percentage in jejunal villi than pigs in CON. Supplementation of PRO1 up-regulated (P < 0.05) MUC2 gene expression in jejunal mucosa and reduced (P < 0.05) PTGS-2 and IL1B gene expression in ileal mucosa on d 21 PI, compared with CON. Pigs in PRO1 had reduced (P < 0.05) relative abundance of families Lachnospiraceae, Peptostreptococcaceae and Pasteurellaceae in the ileum. Conclusions Supplementation of Bacillus subtilis DSM 32540 improved growth performance, alleviated diarrhea severity, enhanced gut health, and reduced systemic inflammation of weaned pigs infected with ETEC F18. Although Bacillus pumilus DSM 32539 was able to alleviate systemic inflammation, it had limited impacts on growth performance and severity of diarrhea of ETEC F18 challenged weaned pigs.

scholarly journals 137 Effects of dietary supplementation with xylanase and probiotics on growth performance and gut health of newly weaned pigs

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 115-115
Author(s):  
M E Duarte ◽  
J Tyus ◽  
S W Kim
Keyword(s):  
Oxidative Stress ◽  
Growth Performance ◽  
Relative Abundance ◽  
Fixed Effects ◽  
Bacterial Abundance ◽  
Jejunal Mucosa ◽  
Gut Health ◽  
Weaned Pigs ◽  
Oxidative Stress Status ◽  
And Oxidative Stress

Abstract This study was to evaluate the supplemental effects of xylanase and probiotics on growth performance and gut health of newly weaned pigs. One hundred and forty-four pigs at 3 weeks of age with an initial body weight (BW) at 6.47 ± 0.03 kg were allotted (4 pigs per pen) to 3 dietary treatments based on a randomized complete block design with sex (gilts and barrow) and initial BW as blocks. The treatments were CON (no supplement), XYL (xylanase at 10,000 XU/kg, Xylamax, BRI, Durham, NC), and PRO (Bacillus spp. 6 x 109 CFU/kg plus xylanase 10,000 XU/kg, EnzaPro, BRI). All diets met the NRC (2012) requirements in 3 phases (P1 for 7 d, P2 for 14 d, and P3 for 14 d). The ADG, ADFI, and G/F were measured weekly. On d 21, 1 pig representing a median BW of each pen was euthanized to collect jejunal samples to measure the immune and oxidative stress status, microbiome, and histology. Data were analyzed using the MIXED procedure of SAS. Treatment was a fixed effect and blocks were random effects. There were no fixed effects among treatments on growth performance, immune and oxidative stress status, and histology. Use of xylanase increased (P &lt; 0.05) the Chao1 index in jejunal mucosa of pigs (24.6 to 29.5). Relative abundance of the Enterobacteriaceae in jejunal mucosa tended to decrease (P = 0.083) with the use of xylanase (16.2 to 1.6%). The PRO increased (P &lt; 0.05) the relative abundance of Mitsuokella compared with others treatments (0.9 vs. 4.8%). In conclusion, supplementation of xylanase or Mitsuokella can enhance the microbiome in jejunal mucosa by increasing the diversity and beneficial bacterial abundance, whereas by reducing pathogenic bacterial abundance without affecting the growth performance, histology, immune, and oxidative stress status.

scholarly journals PSVII-42 Growth performance, gut health, and immune responses of Escherichia coli-challenged weaned pigs fed probiotic-supplemented diets

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 359-360
Author(s):  
Sangwoo Park ◽  
Jinsu Hong ◽  
David Francis ◽  
Caroline J González -Vega ◽  
John K Htoo ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Growth Performance ◽  
Immunoglobulin A ◽  
Dietary Treatment ◽  
Basal Diet ◽  
Gut Health ◽  
Weaned Pigs ◽  
E Coli ◽  
Randomized Design ◽  
Villous Height

Abstract To evaluate the effects of probiotics on performance and gut health of Escherichia coli-challenged weaned pigs, a total of 28 weaned pigs (initial BW = 8.25 kg) were housed individually in pens and fed 4 experimental diets for 21 d in a completely randomized design. The 4 diets were corn-soybean meal-based basal diet without or with 0.25% antibiotics (neomycin + oxytetracycline), 0.05% Bacillus subtilis DSM 32540, or 0.05% Bacillus pumilus DSM 32539. All pigs were orally challenged with K88 strain of E. coli on d 3. Feed intake and BW data, and blood samples were collected on d 3, 7, 14, and 21. Fecal scores were recorded daily. On d 21, pigs were sacrificed to determine gastrointestinal histomorphology, pH and organ weights. Supplementation of the basal diet with antibiotics or B. pumilus did not affect the overall (d 0 to 21) ADG and G:F. The B. subtilis supplementation did not affect the overall ADG, but tended to increase (P &lt; 0.1) the overall G:F by 15%. Fecal score was unaffected by dietary treatment. Supplementation of the basal diet with either probiotic, but not antibiotics increased (P &lt; 0.05) jejunal villous height and reduced (P &lt; 0.05) cecal digesta pH. Supplementation with B. pumilus tended to increase (P &lt; 0.1) colon weight relative to BW; however, antibiotics or B. subtilis supplementation did not affect colon weight. The addition of B. subtilis to basal diet tended to increase (P &lt; 0.1) serum immunoglobulin A concentration on d 21 of the study; however, such effect was not observed with the addition of antibiotics or B. pumilus. In conclusion, dietary B. subtilis improved G:F and jejunal villous height and reduced cecal digesta pH, indicating that dietary supplementation with B. subtilis at 0.05% could improve growth performance and gut health of weaned pigs.

scholarly journals Effect of seaweed-derived laminarin and fucoidan and zinc oxide on gut morphology, nutrient transporters, nutrient digestibility, growth performance and selected microbial populations in weaned pigs

2014 ◽  
Vol 111 (9) ◽  
pp. 1577-1585 ◽  
Author(s):  
G. Heim ◽  
A. M. Walsh ◽  
T. Sweeney ◽  
D. N. Doyle ◽  
C. J. O'Shea ◽  
...  
Keyword(s):  
Growth Performance ◽  
Average Daily Gain ◽  
Live Weight ◽  
Basal Diet ◽  
Nutrient Digestibility ◽  
Gut Health ◽  
Gross Energy ◽  
Weaning Age ◽  
Nutrient Transporter ◽  
Dietary Treatments

In the present study, two experiments were conducted to (1) evaluate the effect of laminarin and/or fucoidan on ileal morphology, nutrient transporter gene expression and coefficient of total tract apparent digestibility (CTTAD) of nutrients and (2) determine whether laminarin inclusion could be used as an alternative to ZnO supplementation in weaned pig diets. Expt 1 was designed as a 2 × 2 factorial arrangement, comprising four dietary treatments (n 7 replicates, weaning age 24 d, live weight 6·9 kg). The dietary treatments were as follows: (1) basal diet; (2) basal diet+300 ppm laminarin; (3) basal diet+240 ppm fucoidan; (4) basal diet+300 ppm laminarin and 240 ppm fucoidan. There was an interaction between laminarin and fucoidan on the CTTAD of gross energy (GE) (P< 0·05) and the expression of sodium–glucose-linked transporter 1 (SGLT1/SLC5A1) and GLUT1/SLC2A1 and GLUT2/SLC2A2 (P< 0·05) in the ileum. The laminarin diet increased the CTTAD of GE and increased the expression of SGLT1, GLUT1 and GLUT2 compared with the basal diet. However, there was no effect of laminarin supplementation on these variables when combined with fucoidan. Expt 2 was designed as a complete randomised design (n 8 replicates/treatment, weaning age 24 d, live weight 7·0 kg), and the treatments were (1) basal diet, (2) basal diet and laminarin (300 ppm), and (3) basal diet and ZnO (3100 ppm, 0–14 d, and 2600 ppm, 15–32 d post-weaning). The laminarin diet increased average daily gain and gain:feed ratio compared with the basal diet during days 0–32 post-weaning (P< 0·01) and had an effect similar to the ZnO diet. These results demonstrate that laminarin provides a dietary means to improve gut health and growth performance post-weaning.

Sign in / Sign up

Export Citation Format

Share Document