82 The impact of feeding treats containing cannabidiol (CBD) on the daily activity level of dogs

Abstract Growing public interest in and use of Cannabidiol (CBD) in companion animals has amplified the need to elucidate potential impacts. The purpose of this investigation was to determine the impact of CBD on daily activity of adult dogs. Twenty-four dogs (18.0 ± 3.4 kg) were utilized in a randomized complete block design with treatments consisting of control, 2 mg CBD/kg BW/d, and 4 mg CBD/kg BW/d split between two treats administered after twice-daily exercise (7:00-9:00 and 17:00-19:00). Four hours each day (10:00-12:00, AM and 13:30-15:30, PM), were designated as time when no persons entered the kennels, with 2 h designated as Quiet Time and the other 2 h as Music Time, where calming music played over speakers. Quiet and Music sessions were randomly allotted to daily AM or PM times. Activity monitors were fitted to dogs’ collars for continuous collection of activity parameters. Data were collected over a 2-wk baseline period to block dogs by activity level (high or low) before randomly assigning dogs within each block to treatments. After 1 wk of treatment adaptation, activity parameters were collected for 2 wk. Data were tested for normality using the UNIVARIATE procedure in SAS before examining differences using the MIXED procedure in SAS, including effects of treatment, day, session (Quiet or Music), time of day (AM or PM), and accompanying interactions. CBD did not alter total activity points (P = 0.9971) or activity duration (P = 0.8776). CBD tended (P = 0.0692) to reduce scratching compared to control. Irrespective of treatment, dogs were more active in PM than AM (P < 0.0001). Regardless of session, dogs receiving 4 mg/kg/d tended (P = 0.0914) to be less active in the PM than control. CBD did not affect activity duration during exercise periods (P = 0.1425), but dogs receiving CBD ran more than control (P = 0.0339). These results indicate that when supplemented up to 4 mg/kg/d, CBD does not negatively impact daily activity levels of dogs.

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Feeding Cannabidiol (CBD)-Containing Treats Did Not Affect Canine Daily Voluntary Activity

Frontiers in Veterinary Science ◽

10.3389/fvets.2021.645667 ◽

2021 ◽

Vol 8 ◽

Author(s):

Elizabeth M. Morris ◽

Susanna E. Kitts-Morgan ◽

Dawn M. Spangler ◽

Jessica Gebert ◽

Eric S. Vanzant ◽

...

Keyword(s):

Daily Activity ◽

Block Design ◽

Activity Patterns ◽

Companion Animals ◽

Time Of Day ◽

Activity Level ◽

Quiet Time ◽

Voluntary Activity ◽

Activity Data ◽

Activity Duration

Growing public interest in the use of cannabidiol (CBD) for companion animals has amplified the need to elucidate potential impacts. The purpose of this investigation was to determine the influence of CBD on the daily activity of adult dogs. Twenty-four dogs (18.0 ± 3.4 kg, 9 months−4 years old) of various mixed breeds were utilized in a randomized complete block design with treatments targeted at 0 and 2.5 mg (LOW) and at 5.0 mg (HIGH) CBD/kg body weight (BW) per day split between two treats administered after twice-daily exercise (0700–0900 and 1,700–1,900 h). Four hours each day [1,000–1,200 h (a.m.) and 1,330–1,530 h (p.m.)] were designated as times when no people entered the kennels, with 2 h designated as Quiet time and the other 2 h as Music time, when calming music played over speakers. Quiet and Music sessions were randomly allotted to daily a.m. or p.m. times. Activity monitors were fitted to dogs' collars for continuous collection of activity data. Data were collected over a 14-day baseline period to establish the activity patterns and block dogs by activity level (high or low) before randomly assigning dogs within each block to treatments. After 7 days of treatment acclimation, activity data were collected for 14 days. Data were examined for differences using the MIXED procedure in SAS including effects of treatment, day, session (Quiet or Music), time of day (a.m. or p.m.), and accompanying interactions. CBD (LOW and HIGH) did not alter the total daily activity points (P = 0.985) or activity duration (P = 0.882). CBD tended (P = 0.071) to reduce total daily scratching compared with the control. Dogs were more active in p.m. sessions than in a.m. sessions (P < 0.001). During the p.m. session, dogs receiving HIGH tended (P = 0.091) to be less active than the control (CON). During the a.m. and p.m. sessions, CBD reduced scratching compared with CON (P = 0.030). CBD did not affect the activity duration during exercise periods (P = 0.143). These results indicate that, when supplemented with up to 4.5 mg CBD/kg BW/day, CBD does not impact the daily activity of adult dogs, but may exert an antipruritic effect.

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Is the impact of adiposity on taste perceptions moderated by chronic physical activity? An overview of the data from NHANES 2013-2014.

10.1101/2021.09.30.21264372 ◽

2021 ◽

Author(s):

Alexandre-Charles Gauthier ◽

Marie-Eve Mathieu

Keyword(s):

Physical Activity ◽

Body Fat ◽

Activity Level ◽

Body Fat Percentage ◽

Activity Levels ◽

Fat Percentage ◽

Active Lifestyle ◽

Physical Activity Levels ◽

Tip Test ◽

The Impact

Introduction Taste is a key sensory modulator of eating behaviour and thus energy intake. The effects of acute exercise has recently been confirmed especially regarding sweet and salty tastes. Physical activity is a safe and effective countermeasure to certain types of chemosensory losses, especially in older populations. Knowing that taste can be impaired with increased adiposity, it is unknown if the adoption of an active lifestyle on a regular basis can mitigate such impairments. Methods Data were extracted from NHANES 2013-2014 database. Perception of salt and bitter tastes for Tongue Tip Test and Whole Mouth Test, physical activity levels over an 8-9-day period and adiposity were analyzed. Moderation analyses were used to study the impact of adiposity on taste perceptions, with physical activity level as the moderator. Results The 197 participants (130 males) included in this project had a mean+/-standard deviation age of 49.1+/-5.2 years, a mean body fat percentage of 31.7+/-7.6% and mean daily physical activity levels of 11 084+/-3531 Monitor-Independent Movement Summary unit (MIMS). The positive association between adiposity and both bitter Tongue Tip Test and overall result (salt+bitter) of Tongue Tip Test were moderated by the adoption of an active lifestyle, with better taste scores observed in individuals achieving higher physical activity levels. When moderation analysis were stratified by gender, the effect of physical activity was no longer significant. Perspectives This study is the first to evaluate the influence of an active lifestyle on the preservation of some taste perceptions across a wide range of adiposity levels. While differences in taste can be observed regarding body fat percentage, physical activity moderates that relation only when men and women are analysed together.

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Activity of the Eta-Aquariid and Orionid meteor showers

Astronomy and Astrophysics ◽

10.1051/0004-6361/202038115 ◽

2020 ◽

Vol 640 ◽

pp. A58 ◽

Cited By ~ 1

Author(s):

A. Egal ◽

P. G. Brown ◽

J. Rendtel ◽

M. Campbell-Brown ◽

P. Wiegert

Keyword(s):

Activity Level ◽

Optical Observations ◽

Detection Methods ◽

Activity Levels ◽

Peak Activity ◽

Meteor Showers ◽

Meteoroid Streams ◽

Activity Duration ◽

Annual Activity ◽

Good Agreement

Aims. We present a multi-instrumental, multidecadal analysis of the activity of the Eta-Aquariid and Orionid meteor showers for the purpose of constraining models of 1P/Halley’s meteoroid streams. Methods. The interannual variability of the showers’ peak activity and period of duration is investigated through the compilation of published visual and radar observations prior to 1985 and more recent measurements reported in the International Meteor Organization (IMO) Visual Meteor DataBase, by the IMO Video Meteor Network and by the Canadian Meteor Orbit Radar (CMOR). These techniques probe the range of meteoroid masses from submilligrams to grams. The η-Aquariids and Orionids activity duration, shape, maximum zenithal hourly rates values, and the solar longitude of annual peaks since 1985 are analyzed. When available, annual activity profiles recorded by each detection network were measured and are compared. Results. Observations from the three detection methods show generally good agreement in the showers’ shape, activity levels, and annual intensity variations. Both showers display several activity peaks of variable location and strength with time. The η-Aquariids are usually two to three times stronger than the Orionids, but the two showers display occasional outbursts with peaks two to four times their usual activity level. CMOR observations since 2002 seem to support the existence of an ~12 yr cycle in Orionids activity variations; however, additional and longer term radar and optical observations of the shower are required to confirm such periodicity.

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The Impact of Enrollment in an Instructional Physical Activity Program Course on the Physical Activity Level and Enjoyment of Physical Activity of University Students

American Journal of Health Studies ◽

10.47779/ajhs.2018.64 ◽

2020 ◽

Vol 33 (3) ◽

Author(s):

Grant M. Hill ◽

Bernard D. Goldfine ◽

Kandice J. Porter ◽

Zenong Yin

Keyword(s):

Physical Activity ◽

Treatment Group ◽

Physical Activity Level ◽

Activity Level ◽

Physical Activity Program ◽

Control Group ◽

Activity Levels ◽

Activity Program ◽

Training Control ◽

The Impact

e purposes of this research were to determine whether participation in a university elective instruction-al physical activity program course (IPAP) would increase the weekly physical activity level of students and resultin a signi cantly higher score on the Physical Activity Enjoyment Scale (PACES). Treatment-group participantswere enrolled in an elective IPAP course that was either sport-based (e.g., volleyball, tennis) or physical condi-tioning-based (e.g., aerobic/strength training). Control-group participants (N=180) were students from the sameuniversities who were not enrolled during that term in an IPAP course. Student responses to the Godin-ShephardLeisure-Time Physical Activity Questionnaire indicated within-group changes in pre vs. post physical activity thatwere signi cant for the treatment group, but not the control group. Results indicate participation in an IPAPcourse signi cantly increases the physical activity levels of students and also signi cantly increases the physical activ-ity enjoyment of students with the most sedentary lifestyles.

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Solar rotational cycle in lightning activity in Japan during the 18–19th centuries

Annales Geophysicae ◽

10.5194/angeo-36-633-2018 ◽

2018 ◽

Vol 36 (2) ◽

pp. 633-640 ◽

Cited By ~ 1

Author(s):

Hiroko Miyahara ◽

Ryuho Kataoka ◽

Takehiko Mikami ◽

Masumi Zaiki ◽

Junpei Hirano ◽

...

Keyword(s):

Solar Activity ◽

Solar Rotation ◽

Galactic Cosmic Rays ◽

Activity Level ◽

Lightning Activity ◽

Activity Levels ◽

Rotational Period ◽

Solar Activity Level ◽

The Impact

Abstract. Thunderstorm and cloud activities sometimes show a 27-day period, and this has long been studied to uncover a possible important link to solar rotation. Because the 27-day variations in the solar forcing parameters such as solar ultraviolet and galactic cosmic rays become more prominent when the solar activity is high, it is expected that the signal of the 27-day period in meteorological phenomena may wax and wane according to the changes in the solar activity level. In this study, we examine in detail the intensity variations in the signal of the 27-day solar rotational period in thunder and lightning activity from the 18th to the 19th centuries based on 150-year-long records found in old diaries kept in Japan and discuss their relation with the solar activity levels. Such long records enable us to examine the signals of solar rotation at both high and low solar activity levels. We found that the signal of the solar rotational period in the thunder and lightning activity increases as the solar activity increases. In this study, we also discuss the possibility of the impact of the long-term climatological conditions on the signals of the 27-day period in thunder/lightning activities. Keywords. Meteorology and atmospheric dynamics (lightning)

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Impact of Social Distancing Associated with The COVID-19 Pandemic on Physical Activity Levels and Associations With Mood State: An Internet-Based Survey

10.21203/rs.3.rs-113847/v1 ◽

2020 ◽

Author(s):

Paulo Puccinelli ◽

Taline da Costa ◽

Aldo Seffrin ◽

Claudio de Lira ◽

Rodrigo Vancini ◽

...

Keyword(s):

Physical Activity ◽

Mood Disorders ◽

Family Income ◽

Negative Impact ◽

Mood State ◽

Activity Level ◽

Activity Levels ◽

Social Distancing ◽

Physical Activity Levels ◽

The Impact

Abstract BACKGROUND: The coronavirus disease 2019 (COVID-19) pandemic has resulted in a strong negative impact on economic and social life worldwide. It has also negatively influenced people’s general health and quality of life. The aim of the present study was to study the impact of social distancing on physical activity level, and the association between mood state (depression and anxiety level) or sex with actual physical activity levels, the change in physical activity during social distancing period, the adhesion level to social distancing, the adoption time of social distancing, family income and age. METHODS: A self-administered questionnaire with personal, quarantine, physical activity, and mood state disorders information’s was answered by 2,140 female and male Brazilians who were recruited through online advertising. RESULTS: Thirty percent of the participants presented symptoms of moderate/severe depression and 23.3% displayed moderate/severe anxiety symptoms. A greater presence of symptoms related to anxiety and depression were associated with low physical activity levels, low family monthly income, and younger age. A higher percentage of men who had no mood disorders was observed among those who were very active than among those less active. CONCLUSION: The COVID-19 pandemic has a negative impact on physical activity. Those who reduced their level of physical activity had the highest levels of mood disorders. Therefore, considering all the non-communicable diseases and mental diseases associated with physical inactivity, humans are likely to be much more vulnerable during this period of social distancing, including that of combating a possible COVID-19 disease. Therefore, physical activity programs should be encouraged, while respecting the necessary social distancing to prevent the spread of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).

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Early-life behaviour predicts first-year survival in a long-distance avian migrant

Proceedings of The Royal Society B Biological Sciences ◽

10.1098/rspb.2020.2670 ◽

2021 ◽

Vol 288 (1942) ◽

pp. 20202670

Author(s):

Shay Rotics ◽

Sondra Turjeman ◽

Michael Kaatz ◽

Damaris Zurell ◽

Martin Wikelski ◽

...

Keyword(s):

Early Life ◽

Daily Activity ◽

Survival Rates ◽

Activity Level ◽

First Year ◽

Activity Levels ◽

Long Distance ◽

Body Acceleration ◽

In The Wild ◽

Migratory Experience

Early-life conditions have critical, long-lasting effects on the fate of individuals, yet early-life activity has rarely been linked to subsequent survival of animals in the wild. Using high-resolution GPS and body-acceleration data of 93 juvenile white storks ( Ciconia ciconia ), we examined the links between behaviour during both pre-fledging and post-fledging (fledging-to-migration) periods and subsequent first-year survival. Juvenile daily activity (based on overall dynamic body acceleration) showed repeatable between-individual variation, the juveniles' pre- and post-fledging activity levels were correlated and both were positively associated with subsequent survival. Daily activity increased gradually throughout the post-fledging period, and the relationship between post-fledging activity and survival was stronger in individuals who increased their daily activity level faster (an interaction effect). We suggest that high activity profiles signified individuals with increased pre-migratory experience, higher individual quality and perhaps more proactive personality, which could underlie their superior survival rates. The duration of individuals’ fledging-to-migration periods had a hump-shaped relationship with survival: higher survival was associated with intermediate rather than short or long durations. Short durations reflect lower pre-migratory experience, whereas very long ones were associated with slower increases in daily activity level which possibly reflects slow behavioural development. In accordance with previous studies, heavier nestlings and those that hatched and migrated earlier had increased survival. Using extensive tracking data, our study exposed new links between early-life attributes and survival, suggesting that early activity profiles in migrating birds can explain variation in first-year survival.

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Effect of sex, age, and reproductive status on daily activity levels and activity patterns in jaguars (Panthera onca)

Mammal Research ◽

10.1007/s13364-021-00589-0 ◽

2021 ◽

Author(s):

Włodzimierz Jędrzejewski ◽

Ilad Vivas ◽

Maria Abarca ◽

Margarita Lampo ◽

Luis G. Morales ◽

...

Keyword(s):

Activity Pattern ◽

Daily Activity ◽

Activity Patterns ◽

Activity Level ◽

Reproductive Status ◽

Activity Levels ◽

Adult Males ◽

Movement Activity ◽

Daily Movement ◽

Reproductive Females

AbstractAll animals, including carnivores, adapt their daily activity duration and distribution to satisfy food demands, breed, or avoid mortality risk. We used the kernel density method to estimate daily movement activity levels and movement activity patterns of jaguars in Hato Piñero, in Venezuelan Western Llanos, based on 3,656 jaguar detection time records from two and a half years of camera trapping. Jaguars were active for 11.7 h per day on average and exhibited mostly nocturnal and crepuscular activity pattern, however, with marked differences between sex/age/reproductive groups. Reproductive females had the highest daily activity level (13.2 h/day), followed by adult males (10.9 h/day), non-reproductive females (10.5 h/day), and cubs (8.7 h/day). Activity patterns also differed, with males and reproductive females having activity peaks at the same hours after sunset and before sunrise, cubs in the night and after sunrise, while non-reproductive females were most active during night hours. This study was the first to document the effect of sex, age, and reproductive status on daily level and activity pattern in the jaguar.

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290 ENZYMATIC ACTIVITY LEVEL OF SOME GLYCOSIDASES IN BOVINE OVIDUCTAL FLUID AT DIFFERENT STAGES OF THE ESTROUS CYCLE

Reproduction Fertility and Development ◽

10.1071/rdv19n1ab290 ◽

2007 ◽

Vol 19 (1) ◽

pp. 260 ◽

Cited By ~ 1

Author(s):

C. Carrasco ◽

R. Romar ◽

J. Marcos ◽

M. Aviles ◽

P. Coy

Keyword(s):

Enzymatic Activity ◽

Corpus Luteum ◽

Estrous Cycle ◽

Luteal Phase ◽

Reproductive Tract ◽

Total Activity ◽

Activity Level ◽

Cycle Phase ◽

Activity Levels ◽

Oviductal Fluid

Carbohydrates play a key role in different reproductive events such as the sperm–oviductal cell interaction and sperm–oocyte recognition. In this way, α-d-mannosyl (Amari et al. 2006 Mol. Reprod. Dev. 59, 221–226) and α-2,3-sialic acid (Velasquez et al. 2006 Mol. Reprod. Dev. in press) residues contained in the zona pellucida have been identified as sperm receptors in bovine oocytes. The glycosidases, enzymes that remove carbohydrates, could play an important role in the reproductive tract, modulating decisive physiological events mediated by carbohydrates. However, the enzymatic activity level of these enzymes or its fluctuations throughout the estrous cycle in the bovine oviductal fluid (BOF) has not been studied. The objective of this work was to compare the enzymatic activity level of 7 different glycosidases in the oviductal fluid of cows at different stages of the estrous cycle. Oviducts were collected from the abattoir and classified according to the macroscopic aspect of the genital tract (Grippo et al. 1995 J. Reprod. Fertil. 105, 57–64) as early follicular (presence of growing follicles), late follicular (presence of a dominant follicle), early luteal phase (ovaries showing a corpus hemorrhagicum or a recent corpus luteum), and late luteal phase (old corpus luteum or corpus albicans). Oviductal fluid samples were collected by aspiration with an automatic pipette making simultaneous manual pressure from the isthmus toward the ampulla. Samples (9 per group) were centrifuged (7000g, 10 min) and supernatant was stored at −20°C until assay. Total activity levels were fluorimetrically measured at 450 nm, with the corresponding substrate conjugated to 4-methylumbelliferil for each enzyme (Abascal et al. 1998 Biochem. J. 333, 201–207) using a fluorometer Fluostar Galaxy (BMG LABTECH GmbH, Offenberg, Germany). Enzymatic assays were done in duplicate for 4 h at 37°C, and the reactions were stopped by adding glycine-calcium carbonate buffer. Fluorescences were corrected for tissue and substrate blanks. Fluorescence results of each enzyme and oviduct phase were analyzed using a 1-way ANOVA, with estrous cycle phase being the main factor. Results (mean counts of fluorescence) showed that the level of activity changes during the estrous cycle and the activity of some enzymes increases close to or after ovulation, suggesting a role of some glycosidases in the fertilization process. Preliminary assays for neuraminidase were negative for all samples. Future studies are necessary to identify the biological role played by the glycosidases present in the bovine oviductal fluid. Table 1.Enzymatic activity level of some glycosidases in bovine oviductal fluid at different stages of the estrous cycle This work was supported by Fundación Séneca (03018/PI/05) and MEC (Project code 3495).

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The assessment of pain, flexibility and daily activity level in the patients who had facet tropism

International Journal of Scientific Reports ◽

10.18203/issn.2454-2156.intjscirep20201599 ◽

2020 ◽

Vol 6 (5) ◽

pp. 172

Author(s):

Busra Kizilkan ◽

Cetin Sayaca ◽

Ozlem Turkoglu

Keyword(s):

Daily Activity ◽

Joint Angle ◽

Facet Joint ◽

Nottingham Health Profile ◽

Activity Level ◽

Control Group ◽

Activity Levels ◽

Lateral Flexion ◽

Significant Difference ◽

Facet Tropism

Background: The aim of this study to investigate the relationship between asymmetric angular value in lumbar facet joints and pain, flexibility and daily activity level.Methods: The study included 51 patients with complaint of low back pain (LBP) and underwent lumbar magnetic resonance imaging. Facet joint angle measurements of L4-L5 and L5-S1 were measured. Visual analogue scale (VAS) was used for severity of pain. Joint range of motions (ROM) was measured via goniometry. Body extensibility measurements were performed via body hyperextension test. The Nottingham health profile scale was used to assess daily activity level of individuals. Results: The VAS values of patients with tropism were significantly higher (p=0.016). There wasn’t significance difference in ROM and flexibility (p=0.784). In patient group with facet tropism, there was limit of lateral flexion towards the side where the facet joint angle was larger than the control group (p=0.002). There was no significant difference between daily activity levels of both groups (p=0.755).Conclusions: Pain severity of facet tropism patients is higher. Patients with facet tropism had lateral flexion restriction. In the light of these findings, when the lateral flexion limitation is detected in individuals with complaints of pain without discopathy, it’s necessary to make MR measurements in differential diagnosis by considering facet joint tropism, and to plan physiotherapy and rehabilitation programs. As a result, tropism should be questioned in patients suffering from LBP and limited lateral flexion. There is need for studies in which different evaluation and treatment methods are applied for tropism.

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