Effect of long-term feeding of graded levels of deoxynivalenol on performance, nutrient utilization, and organ health of grower-finisher pigs (35-120 kg)

Author(s):  
Michael O Wellington ◽  
Michael A Bosompem ◽  
Lucas A Rodrigues ◽  
Daniel A Columbus

Abstract The objective of this study was to evaluate the effect of long-term feeding of graded levels of DON on performance, nutrient utilization, and organ health of grower-finishing pigs. A total of 240 mixed-sex grower-finisher pigs (35.9 ± 1.1 kg initial body weight) were randomly assigned to 1 of 4 dietary treatments (6 pigs/pen; 10 pens/treatment) for 77 d. Diets consisted of a control diet without DON (CONT) and diets containing 1, 3, or 5 ppm DON (DON1, DON3, or DON5). Nitrogen-balance was determined in 1 pig/pen during week 6 and 12 of the study. Growth performance measures were taken weekly for average daily feed intake (ADFI), average daily gain (ADG), and gain:feed (GF) until d 77. Blood samples were collected on d 0, 14, 42, 56, and 84 from 1 pig/pen for analysis of indicators of liver and kidney function. On d 7, ADG and ADFI for pigs fed DON3 and DON5 diets were lower (P < 0.05) compared to DON1- and CONT-fed pigs. Overall ADG and ADFI (d 0-77) were lower in DON3- and DON5-fed pigs compared to CONT and DON1 pigs (P < 0.05), with no difference in GF (P > 0.05). Final body weight was reduced in DON3- and DON5-fed pigs (P < 0.05) compared to CONT and DON1, which were not different (P > 0.05). No significant (P > 0.05) treatment effects were observed on carcass characteristics. In the grower-phase, protein deposition (PD) was reduced in DON3 and DON5 pigs compared to CONT and DON1 pigs (P < 0.05). In the finisher phase, PD was not affected by dietary treatment (P > 0.05). There was no effect of dietary treatment on the majority of selected serum chemistry (P > 0.05). In summary, pigs exposed to diets containing > 1 ppm DON had reduced growth performance with little or no effect on nitrogen utilization, organ health, or carcass characteristics, suggesting that the negative effects of DON may be largely due to depressed feed intake.

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 67-68
Author(s):  
Michael A Bosompem ◽  
Michael O Wellington ◽  
Daniel A Columbus

Abstract Previous studies examining the effects of deoxynivalenol (DON) intake in pigs have largely focused on young animals or have been over a short period of time. The objective of the present study was to determine the effects of long-term feeding of DON contaminated diets on growth performance of grower-finisher pigs. A total of 240 mixed-sex pigs (35.9 ± 1.1 kg) were group housed in 6 pigs/pen (n = 10/treatment) and were randomly assigned to 1 of 4 dietary treatments for 77 d. Diets consisted of a control diet (CON) containing no DON or a diet containing 1, 3, or 5 ppm DON (DON1, DON3, or DON5) achieved by adding DON-contaminated wheat and wheat screenings at the expense of clean wheat. In the grower period, DON5-fed pigs had reduced average daily gain (ADG) compared to CON, with DON1 and DON3-fed pigs being intermediate P < 0.05). There was no effect of dietary treatment on ADG in the finisher period (P > 0.05). Overall the entire study, DON3 and DON5-fed pigs had similar and reduced ADG (P < 0.05) compared to CON and DON1, which did not differ (P > 0.05). Feed intake was reduced in DON-fed pigs in the finisher period (3.12, 2.97, 2.96, and 2.88 ± 0.05; P< 0.05) and in DON3 and DON5-fed pigs overall (2.62, 2.55, 2.47, 2.47 ± 0.03; P < 0.05) compared to CON, with no overall effect observed in the grower period. There was no effect on feed efficiency in any period (P > 0.05). The decrease in performance resulted in reduced final body weight in DON3 and DON5-fed pigs, compared to CON, with DON1-fed pigs being intermediate (P > 0.05). Overall, the effects of DON-intake on performance were variable and generally occurred rapidly after initial exposure and appear to be largely due to the reduction in feed intake.


2020 ◽  
Vol 45 (1) ◽  
pp. 131-140
Author(s):  
U. E. Ewa

The performance of broiler chickens fed boiled, boiled with potash (akanwu) (BWA) or boiled and mix with enzyme (BME) mucuna seed meal( MSM) were investigated. 120 a week old broiler chicken were randomly assigned to 4 treatment diets in a completely randomized experiment that lasted for 49 days. The diets were made of control (soya bean based), D2 (5% boiled MS), D3 (5% BWA MSM) and D4 (5% BME). The proximate composition of mucuna was determined. Other parameters measured were: feed intake, weight gain, and carcass characteristics of broilers. The crude protein content ranged from 22.10-22.16%, while the energy level ranged from 2996.10-3003.60kcal/kg. For growth performance, significance differences (P<0.05)exist for final body weight, ,total weight gain, daily weight gain and feed to gain ratio except for initial body weight, total feed intake, daily feed intake and mortality. BME gave the best growth performance in terms of significant (P<0.05) higher final body weight (2566.50g), total weight gain (2489.20g), and better feed to gain ratio (2.25) than the control which had: 2198.30g, 2095.10g and 2.56 for FBW, TWG and FGR respectively. For the carcass characteristics, chickens fed diet 4(BME) was not significantly (P>0.05) different from the control for dressed weight and dressed weight percentage. Control diet had the highest breast cut (31.87%) and diet 4 had the lowest (28.57%) while D4 had the highest thigh cut (18.34%) but the control had the lowest (16.41%). For cost per kg weight gain and gross margin, D4 gave 235.03 and 708.64 respectively, which compared (P>0.05) with the control ( 231.71, 746.68). The revenue and gross margin valuesobserved were direct indices of the biological effects observed in the growth performance (Table 4). From the above, Diet 4 which is boiled mucuna seed meal mixed with enzyme is therefore chosen as the best in terms of cost/Kg weight gain, revenue and gross margin in that it compared favorably with the control diet (D1).  


Author(s):  
Amr M.A. Elmasry ◽  
Luis A. Miranda ◽  
Germán Mendoza ◽  
Fernando X. Plata

Background: The effects of the probiotics vary with the doses and strains used for this reason, a study was conducted over 35 days to determine the effect of live yeast supplementation in the diet of growing rabbits on growth performance and apparent nutrient digestibility.Methods: A total of 60 New Zealand and California rabbits (5 weeks old, average body weight 0.881±0.015 kg) were housed in 30 cages. They were fed with a control diet based on alfalfa and maize or barley grains and supplemented with Procreatin®7 (Saccharomyces cerevisiae CNCM I 1077) or Biosaf® SC47 (Saccharomyces cerevisiae NCYC Sc47) at three doses, namely 0, 6.4, or 12.8 ×109 CFU per kg basal diet.Result: The higher yeast concentration had a positive effect (P less than 0.01) on final body weight (BW), average daily gain (ADG) and carcass weight (CW). However, there were no significant differences in dry matter intake. As a result of this, the feed conversion ratio (FCR) decreased (P less than 0.01). Significant increases (P less than 0.05) in nutrient digestibility (DM, OM, NDF and ADF) were observed with both grains. The use of yeast in maize and barley-based diets of rabbits has positive effects on growth performance and nutrient digestibility.


2021 ◽  
Vol 43 (1) ◽  
pp. 254-262
Author(s):  
A. O. Aniebo

The effect of dietary treatments on growth performance, haematological and biochemical indices of finisher broilers as well as economics of broiler production were determined in this fermented cassava flour/blood mixture code-named "cassablood". The control diet (T1) contained 0% cassablood, while diets 2, 3 and 4 contained 20%, 25% and 30% cassablood respectively. 120 four weeks old Anak broiler chicken were randomly allocated the 4 diets with 30 birds per treatment replicated 3 times with ten 10 broilers per replicate in a completely randomized design (CRD). Treatment effects on final body weight, final weight gain, feed intake and seed conversion ratio were significant (P<0.05). Birds fed cassablood based diets compared favourably with the control diet. 20% cassablood inclusion performed equally with the control diet in feed intake, body weight gain and feed conversion ratio.All dietary groups also showed no significant differences (P>0.05) in most haematological and serum biochemical indices of broilers except in cholesterol, glucose and triglyceride contentswhichdiffered (P<0.05) significantly. Similarly, chicken on 20% and 25% inclusion levels produced significantly (P < 0.05) higher economic gains in terms of feed cost per kilogram of broiler among all the treatments. Therefore, 20 - 25% cassablood dietary inclusion level was recommended in broiler diet for production and profit maximization.  


2021 ◽  
Vol 34 (1) ◽  
pp. 102-108
Author(s):  
Hyunjun Choi ◽  
Sang Yun Ji ◽  
Hyunwoong Jo ◽  
Minho Song ◽  
Beob Gyun Kim

Objective: The objective of this study was to investigate the influence of dietary lead (Pb) supplementation and feeding period on growth performance, organ weight, and Pb accumulation in pigs.Methods: In a 56-day feeding experiment, a total of 48 barrows with initial body weight 10.4±0.6 kg were allotted to 2 dietary treatments (0 and 200 mg/kg of supplemental Pb) in a completely randomized design with 6 replicates. Body weight and feed intake were recorded to calculate growth performance. At the end of each 14 day-period (on days 14, 28, 42, and 56), an animal was randomly selected from each pen and slaughtered to collect blood samples, hair samples, left 5th rib, heart, liver, kidneys, lungs, and longissimus dorsi muscle samples.Results: Average daily gain and average daily feed intake were reduced (p<0.05) by supplemental Pb during the day 42 to 56. Relative kidney weight to body weight was linearly increased with increasing feeding period in pigs fed the Pb-supplemented diet, but not in pigs fed the control diet (p<0.05). The Pb concentrations in hair, left 5th rib, kidneys, and lungs were linearly increased with longer feeding period in pigs fed the Pb-supplemented diet, but not in pigs fed the control diet (p<0.01).Conclusion: Dietary Pb supplementation caused growth retardation and Pb accumulation in most organs, particularly in hair, bone, and kidneys in a time-dependent manner.


Animals ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 362 ◽  
Author(s):  
Seyed Ghoreyshi ◽  
Besma Omri ◽  
Raja Chalghoumi ◽  
Mehrdad Bouyeh ◽  
Alireza Seidavi ◽  
...  

L-carnitine as well as lysine and methionine are amino acids of important nutritional and nutraceutical interest and are used in nutritional strategies as dietary supplements to improve feed quality characteristics in animals and broiler chicken in particular. This study investigated the effect of different levels of L-carnitine and extra levels of lysine-methionine on growth performance, carcass characteristics, and some immune system markers. Two hundred seventy male Ross 308 broilers were a fed control diet (C) and eight different diets supplemented with an excess of amino acids. In the experimental diets, identified as D1, D2, D3, D4, D5, D6, D7, and D8, extra L-carnitine, lysine, and methionine were added in excess with respect to the American National Research Council (NRC) recommendations: L-carnitine equal to NRC (D1), control diet supplemented with lysine at 30% in excess of NRC, methionine at 30% in excess of NRC, and L-carnitine equal to NRC (D2), control diet supplemented with lysine equal to NRC, methionine equal to NRC, and L-carnitine at 15% in excess of NRC (D3), control diet supplemented control diet supplemented with lysine at 15% in excess of NRC, methionine at 15% in excess of NRC, and L-carnitine at 15% in excess of NRC (D4), control diet supplemented lysine at 30% in excess of NRC, methionine at 30% in excess of NRC, and L-carnitine at 15% in excess of NRC (D5), control diet supplemented with lysine equal to NRC recommendations, methionine equal to NRC recommendations, and L-carnitine at 75% in excess of NRC (D6), control diet supplemented with lysine at 15% in excess of NRC, methionine at 15% in excess of NRC, and L-carnitine at 75% in excess of NRC (D7), and control diet supplemented with lysine at 30% in excess of NRC, methionine at 30% in excess of NRC, and L-carnitine at 75% in excess of NRC (D8). During the starter and growth phases, feed intake was not affected by dietary treatment (p > 0.05). By contrast, body weight and FCR were both affected (p < 0.001) during the starter period. During the finisher phase, feed consumption was affected (p < 0.05) by dietary treatment. Feed intake of broilers fed on C, D3, D6, and D7 were statistically similar (p > 0.05) (1851.90, 1862.00, 1945.10, and 1872.80 g/pen/day, respectively) and were higher (p < 0.05) than 1564.40 g/pen/day (D5). With the exception of drumsticks, neck, back thoracic vertebrae, and proventriculus weights, the economical carcass segments were not affected (p > 0.05) by the dietary supplementation of amino acids. Duodenum and ileum weights and lengths decreased with amino acid supplementation (p < 0.05). IgT and IgG titers against Sheep Red Blood Cells (SRBC) for both primary and secondary responses were not affected by dietary treatments (p > 0.05). Dietary amino acids supplementation did not affect IgM titer after the secondary challenge (p > 0.05) and had a significant effect (p < 0.05) on serum antibody titers in broilers vaccinated against Newcastle disease (NCD) and Gumboro ‘s disease at the 27th and 30th days, respectively.


Animals ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 3588
Author(s):  
Hao Yang ◽  
Yingjie Wang ◽  
Mengru Liu ◽  
Xiao Liu ◽  
Yihan Jiao ◽  
...  

The aim of this study was to explore the effect of dietary resveratrol on the growth performance and anti-inflammatory mechanism in ducks. A total of 280 one-day-old specific pathogen-free male ducklings (Anas platyrhynchos) with an average body weight of 35 ± 1 g were randomly divided into two dietary treatment groups with different supplementation levels of resveratrol for growth performance experiments: R0 and R400 (0 and, 400 mg kg−1 resveratrol, respectively). At the age of 28 days, 16 ducks were selected from each treatment group and divided into four subgroups for a 2 × 2 factorial pathological experiment: R0; R400; R0 + LPS; R400 + LPS, (0 mg kg−1 resveratrol, 400 mg kg−1 resveratrol, 0 mg kg−1 resveratrol, 400 mg kg−1 resveratrol + 5 mg lipopolysaccharide/kg body weight). The results showed that resveratrol significantly improved final body weight and average daily gain (p < 0.01) and alleviated the lipopolysaccharide-induced inflammatory response with a reduction in IL-1β and IL-6 in the plasma and the liver (p < 0.05). Resveratrol improved mRNA levels of Nrf2 and HO-1 and decreased the mRNA levels of TLR4 and NF-κB in duck liver (p < 0.05). Dietary resveratrol can improve growth performance and reduce inflammation through the Nrf2/HO-1 and TLR4/NF-κB signaling pathways in duck.


2013 ◽  
Vol 42 (2) ◽  
pp. 81-88
Author(s):  
S Islam ◽  
MA Hoque ◽  
MAMY Khandoker ◽  
NG Saha ◽  
A Akhtar

The present study was conducted using records on four breeding bulls maintained at the Artificial Insemination (AI) Center of Bangladesh Agricultural University (BAU), Mymensingh and on 154 of their progeny maintained at BAU Dairy Farm (112) and some villages (42 progeny) adjacent to BAU for estimating the effect of breeding bulls and genetic parameters on early growth performance of the progeny at farm and field levels. Genetic correlations between traits of bulls and their progeny were also estimated. Bull traits were metabolic body weight (MWT), feed intake (FI) and residual feed intake (RFI) where progeny traits were birth weight (BWT), final body weight (FWT) at 90 days of age and average daily gain (ADG). Mean BWT of progeny at farm and field level was 16.34±1.85 to 17.62±1.97 kg and 13.89±2.78 to 16.11±2.98 kg, respectively. The FWT at farm progeny was 48.9±2.87 to 55.67±2.14 kg whereas 43.43±2.50 to 52.22±3.34 kg for field progeny. The ADG at farm and field progeny was 0.36±0.03 to 0.43±0.01 and 0.32±0.03 to 0.42±0.03 kg, respectively. The BWT and FWT of farm progeny were significantly (p>0.05) higher than the progeny of field level. Breeding bulls had significant (p<0.05) effect on FWT and ADG for both of the farm and field progeny. Estimated heritability was found to be moderate in case of BWT (0.32±0.19), but low for FWT (0.26±0.18) and ADG (0.29±0.20) for pooled average. The genetic correlation between bulls’ MWT and BWT was high (rg=0.54±0.17), but low with FWT(rg=0.26±0.18) and ADG (rg=0.28±0.23). Moderate in daily FI of bulls was genetically correlated with BWT (0.45±0.22), FWT (0.38±0.24) and ADG (0.35±0.25) for their progeny, while low but favorable negative genetic correlation (rg=-0.13±0.17) was observed between ADG of progeny and RFI of bulls. The negative correlation for RFI with ADG suggested that selection might result in better success in improving herd production efficiency without compromising progeny growth performance. DOI: http://dx.doi.org/10.3329/bjas.v42i2.18484 Bang. J. Anim. Sci. 2013. 42 (2): 81-88 


2020 ◽  
Vol 47 (3) ◽  
pp. 149-154
Author(s):  
A. A. Malik ◽  
Y. S. Kudu ◽  
M. Abdullahi ◽  
M. J. Ibrahim

Conventional feed resources for livestock are increasingly becoming more expensive, due to competition with man; hence nutritionists are searching for cheaper, locally-available alternatives. A total of forty-five (45) mixed sex weaner rabbits, aged 5 – 6 weeks, with average initial weights of between 694.42 and 761.10 g were used to investigate the effect of varying levels of cowpea milling waste (CMW) diets on their growth performance and nutrient digestibility. They were randomly allotted to five dietary treatments with nine rabbits per treatment. The control treatment (T1) contained 0 % CMW while treatments T2, T3, T4 and T5 had 10, 20, 30 and 40 % CMW dietary inclusion levels, respectively. Clean water and feed were offered ad libitum daily to the rabbits, and record of their feed intake and growth performance were taken for 12 weeks. At the end of the 11th week, a nutrient digestibility trial was carried out. Results show that there were no significant (P>0.05) differences in final body weight, body weight gain, total feed intake and mortality among the dietary treatments. Feed conversion ratio (FCR) for diets T4 (6.65) and T5 (6.66) containing 30 and 40 % CMW respectively, were as good as that of the control diet (6.11). Dry matter and crude protein digestibility showed no significant (P>0.05) difference across the treatments. Digestibility of crude fibre (72.64, 80.16, 84.04 and 80.90 % for T2, T3, T4 and T5 respectively), ether extract (95.98, 94.90, 96.04 and 94.38 % for T2, T3, T4 and T5 respectively), nitrogen free extract (94.30, 95.18, 93.58 and 94.90 % for T2, T3, T4 and T5 respectively), as well as total digestible nutrient (83.69, 76.11, 81.67 and 80.02 % for T2, T3, T4 and T5 respectively) of the test diets compared favourably with that of the control diet (72.94, 95.23, 96.04 and 80.47 % for CF, EE, NFE and TDN respectively). Hence, it can be concluded that CMW can be used safely as a protein source and included up to 40 % in weaner rabbit diets with no detrimental effect on their growth performance and nutrient digestibility.


2020 ◽  
Vol 45 (1) ◽  
pp. 106-114
Author(s):  
U. E. Ewa ◽  
K. U. Amaefula ◽  
A. H. Akinmutimi

Growth performance, carcass characteristics and economics of broiler chicken fed graded levels of raw Mucuna sloanei seed meal were investigated. A total of 150, 1- day old broiler chickens were used. There were five treatments each replicated into three with 10 birds per replicate in a completely randomized design. Five treatment diets were formulated. Diet 1served as control, while diets 2, 3, 4, and 5 had 5, 10, 15, and 20 %, respectively of raw mucuna seed meals (RMSM) added to them. The experiment lasted 49 days. The parameters considered were growth performance, carcass characteristics and economics of production. For growth performance, the result revealed that RMSM significantly (P<0.05) depressed growth as the levels of inclusion of RMSM increased from 0 to 20%. There were significant differences (p<0.05) in all the parameters considered under growth except for initial body weight and mortality. There was progressive loss in final body weight as the level of mucuna inclusion increased from 0% to 20%. Control recorded the highest live body weight of 3023.30g while, birds fed diet with 20% mucuna had the least body weight of 504.43g. Among the birds placed on the test diets, birds fed diet with 5% mucuna seed meal performed significantly (P<0.05) better (1840.00g) than other test diets. Birds fed diets with 10 and 15% mucuna had final body weight of 1180.00 and 726.67g, respectively. The progressive l oss in weight was obvious early in the experiment and at 8 weeks of age the broiler fed 20% raw mucuna. Mucuna sloanei based diet weighed only 504.43g (16.68% of the control) as against 1840.00, (60.86% of the control) for that fed 5%.mucuna. Percentage dressed weight and percentage breast and thigh were significantly (P<0.05) higher for chicken fed control diet. 10% level of raw MSSM gave highest value for drumstick (14.91%) while control gave the least (13.00%). 5% raw MSSM (27. 71%) compared favourably with control (30.60%) for breast cut. Gross margin significantly decreased from N1459.80 for control diet to N 14.20 for D5 as the percentage inclusion of MSSM increases from 0 to 20%. In conclusion, birds fed raw Mucuna sloanei seed meal diet could not compare favourably with those fed soya bean based diets even at 5% level of inclusion. Processing is therefore recommended to enhance performance.


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