Experience in Management of Burn Injury During Pregnancy in a Burn Unit

2020 ◽  
Author(s):  
Inês Correia-Sá ◽  
Marisa Marques ◽  
Ricardo Horta ◽  
António Costa-Ferreira ◽  
Acácio G Rodrigues ◽  
...  
Keyword(s):  
Pregnant Woman ◽  
Medical Treatment ◽  
Pregnant Women ◽  
Burn Injury ◽  
Silver Sulfadiazine ◽  
Cerium Nitrate ◽  
Second Trimester ◽  
Lung Maturation ◽  
Burn Unit ◽  
Second Degree

Abstract Burns injuries during pregnancy are rarely reported in developed countries, but an increasing in mortality and morbidity has been observed. The authors describe their experience in the treatment of pregnant women in a burn unit. A 12-year retrospective study of burns in pregnant women hospitalized was conducted. Since 2008, two pregnant women were admitted in their unit. Patient 1, a 32-year-old pregnant woman on second trimester (27s6d), suffered a second-degree burn injury, 16% total body surface area (TBSA), caused by fire. She was admitted in their burn unit and submitted to medical treatment, wound dressing, and surgical treatment. Cerium nitrate and silver sulfadiazine were used in burn lesions and the patient was submitted to debridement and skin graft surgery. No uneventful events occurred with the fetus. Patient 2 was a 32-year-old pregnant woman on second trimester (26s), HVC positive, admitted with a second-degree flash burn, 8% TBSA. She was submitted to endotracheal intubation before arriving to the hospital due to risk of airway burn. Dexamethasone was administered for fetus lung maturation. No uneventful events were observed. The incidence of thermal injury in pregnancy in Portugal is low. Active medical treatment together with conservative wound care should be the standard in each trimester of pregnancy. Although there is limited safety information on cerium nitrate or silver sulfadiazine during pregnancy, those were used with no adverse effects on one of their patients. Obstetrical management should be individualized.

Does Active Smoking Influence the Second Trimester Biochemical Markers Concentrations?

2017 ◽  
Vol 68 (10) ◽  
pp. 2234-2236
Author(s):  
Dan Navolan ◽  
Florin Birsasteanu ◽  
Adrian Carabineanu ◽  
Octavian Cretu ◽  
Diana Liana Badiu ◽  
...  
Keyword(s):  
Pregnant Woman ◽  
Pregnant Women ◽  
Cigarette Smoke ◽  
Chorionic Gonadotropin ◽  
Reference Values ◽  
Biochemical Markers ◽  
Smoking Status ◽  
Active Smoking ◽  
Second Trimester ◽  
Harmful Effects

Cigarette smoke contains over 7000 different substances some of them exerting harmful effects on embryo and pregnant woman. Nowadays 15 % of adult people and around 10-15% of pregnant women smoke. Previous studies showed that cigarette smoke compounds could exert pharmacodinamic effects and influence some of the second trimester biochemical markers concentration. Therefore there is a need to adjust the reference values of second trimester markers depending of the smoker status. The aim of our study was to analyse which of the markers are influenced by smoking and whether the software used to calculate the risk for aneuploidies is able to counterbalance this influence. Alpha-fetoprotein (AFP), chorionic gonadotropin hormone (hCG) and free estriol (uE3) values were measured in second trimester sera of 1242 pregnant women: 1089 non-smokers and 153 smokers. Only hCG second trimester values were influenced by smoking whereas AFP and uE3 values were not. The correction of medians according to the smoking status was able to counterbalance this effect.

Mucocele of the appendix during pregnancy: What to do?

2017 ◽  
Vol 6 (1) ◽  
Author(s):  
Eva Martínez Franco ◽  
Helena Vallverdú Cartié ◽  
Montserrat Margarit Verano ◽  
José Ramón Méndez Paredes ◽  
Pere Gris Garriga ◽  
...  
Keyword(s):  
Pregnant Woman ◽  
Pregnant Women ◽  
Low Grade ◽  
Second Trimester ◽  
Macroscopic Description ◽  
Surgical Method ◽  
Mucinous Neoplasm ◽  
Mucocele Of The Appendix ◽  
Surgical Treatments ◽  
Selection Of

Abstract The term mucocele is simply defined as the macroscopic description of an appendix that is grossly distended by intraluminal accumulation of mucoid material. Its incidence ranges from 0.2% to 0.7% of all appendectomies and during pregnancy it is even less frequent. After a mucocele diagnosis, the selection of an adequate surgical method is, in general, very important. But during pregnancy it is an even more complicated decision because of the lack of experience and evidence on elective surgical treatments in pregnant women. We present a commentary based on a case of a low-grade appendiceal mucinous neoplasm of the appendix, found on an appendectomy specimen because of a mucocele in a second trimester pregnant woman.

scholarly journals Clinical Case of Arteriovenous Malformation in a Pregnant Woman

2020 ◽  
Vol 5 (6) ◽  
pp. 88-94
Author(s):  
N. A. Abdullaeva ◽  
◽  
V. I Cherepova ◽  
O. L. Tovazhnyanska ◽  
V. V. Lazurenko
Keyword(s):  
Pregnant Woman ◽  
Arteriovenous Malformation ◽  
Pregnant Women ◽  
Clinical Case ◽  
Cerebrovascular Disorders ◽  
Cerebral Vessels ◽  
Second Trimester ◽  
Physiological Time ◽  
Neurosurgical Treatment ◽  
Effective Result

Extragenital pathology during pregnancy and childbirth occupies a leading place in maternal mortality and perinatal pathology. One of the main ways to maintain the health of mother and child is to identify somatic diseases in pregnant women and timely treat them. Nervous system diseases that occur in pregnant women are mainly epilepsy, multiple sclerosis, brain tumors, cerebrovascular disorders, although remain poorly understood, but require immediate decisions to prolong pregnancy, obstetric tactics during childbirth, conservative or conservative surgery. The pathology of cerebral vessels (arterial aneurysms and arteriovenous malformations) also remains an urgent problem, despite many years of experience in their diagnosis and treatment. The sudden development of symptoms, severity of clinical manifestations and high mortality in rupture of an aneurysm or arteriovenous malformation of cerebral vessels determine the urgency of this problem and increased interest in its study, especially in pregnant women. Material and methods. The paper presents a clinical case of arteriovenous malformation in a 25-year-old pregnant woman, her treatment and delivery. Results and discussion. Arteriovenous malformation is considered a congenital cerebrovascular pathology, which is accompanied by a sudden rupture of abnormal vessels with the development of hemorrhagic stroke, without specific clinical symptoms and precursors, which complicates lifelong diagnosis. Endovascular embolization during pregnancy saved the lives of women and children. An effective result was obtained after neurosurgical treatment of arteriovenous malformation in a pregnant woman in the second trimester of pregnancy (17 weeks), which allowed to bring the pregnancy to the physiological time of delivery. Taking into account the complex neurological pathology, neurosurgery, which requires the exclusion of a powerful period of childbirth, a pregnant woman gave birth by cesarean section at 38 weeks of pregnancy. Conclusion. An effective result was obtained after neurosurgical treatment of arteriovenous malformation in a pregnant woman in the second trimester of pregnancy, which allowed to bring the pregnancy to the physiological time of delivery. The obtained results indicated the possibility of full-term pregnancy, reduction of maternal and perinatal morbidity and mortality in pregnant women with arteriovenous malformation with timely preventive and curative measures with timely referral of pregnant women to the perinatal center on the basis of a multidisciplinary clinical institution to prevent complications

scholarly journals Compounded Cerium Nitrate—Silver Sulfadiazine Cream is Safe and Effective for the Treatment of Burn Wounds: A Burn Center’s Four-Year Experience

2021 ◽  
Author(s):  
Adam D Reese ◽  
John W Keyloun ◽  
Gaurav Garg ◽  
Melissa M McLawhorn ◽  
Lauren T Moffatt ◽  
...  
Keyword(s):  
Burn Injury ◽  
Total Body Surface Area ◽  
Blood Gases ◽  
Inhalation Injury ◽  
Silver Sulfadiazine ◽  
Cerium Nitrate ◽  
Burn Wounds ◽  
Blood Gas Monitoring ◽  
Asymptomatic Patients ◽  
Clinically Significant

Abstract Wound infections and sepsis are significant causes of morbidity after burn injury and can be alleviated by early excision and grafting. In situations that preclude early surgery, topical agents allow for a safer delay. Cerium nitrate compounded with silver sulfadiazine (Ce-SSD) is a burn cream that provides broad antibacterial activity, forms a temporary barrier, and promotes re-epithelialization. Methemoglobinemia is a rare, but oft-cited, systemic complication of Ce-SSD. In this retrospective review, 157 patients treated with Ce-SSD between July 2014 - July 2018 were identified and the monitoring protocol for methemoglobinemia during Ce-SSD treatment was evaluated. Median age was 59 years (IQR, 47-70.5 years), with total body surface area burn (TBSA) of 8.5% (IQR, 3-27), adjusted Baux score of 76 (IQR, 59-94), and inhalation injury present in 9.9% of patients. Primary endpoints included incidence of symptomatic and asymptomatic methemoglobinemia. Of the 9.6% (n = 15) of patients with methemoglobinemia, 73.3% (n=11) had maximum methemoglobin levels ≥ 72 hours from time of first application. One patient developed clinically significant methemoglobinemia. Patients with TBSA ≥ 20% were more likely to develop methemoglobinemia (OR 9.318, 95% CI 2.078 to 65.73, p = 0.0078), however neither Ce-SSD doses nor days of exposure were significant predictors. Ce-SSD application to temporize burn wounds until excision and grafting is safe, effective, and, in asymptomatic patients with TBSA < 20%, can be used without serial blood gas monitoring. Vigilant monitoring for symptoms should be performed in patients with TBSA ≥ 20%, but routine blood gases are not necessary.

scholarly journals Status Karies Gigi, Status Kebersihan Gigi dan Mulut dan Status Gingivitis Ibu Hamil Trimester I dan II

2019 ◽  
Vol 1 (1) ◽  
pp. 28-38
Author(s):  
Paulena Fao Lei ◽  
Emma Krisyudhanti ◽  
Christina Ngadilah ◽  
Applonia Leo Obi
Keyword(s):  
Pregnant Woman ◽  
Dental Caries ◽  
Pregnant Women ◽  
Health Center ◽  
Oral Hygiene ◽  
Cold Water ◽  
First Trimester ◽  
Second Trimester ◽  
The Status ◽  
Carious Teeth

Abstract: Dental Caries Status, Status of Dental and Oral Hygiene and Gingivitis Status of Pregnant Women Trimester I and II. Pregnancy is an event that is often encountered in a woman's life because pregnant women are one group that is vulnerable to dental and oral diseases. The purpose of this study: to determine the status of dental caries, the status of dental and oral hygiene, and the status of gingivitis for first and second-trimester pregnant women in Tarus Health Center, Kupang Regency. The research method used is descriptive. sampling with an accidental sampling technique totaling 73 pregnant women who came to the health center Tarus. The results of the study in the first trimester - the average pregnant woman experienced 4 carious teeth included in the medium category, and the second trimester the average pregnant woman had 4 carious teeth including the moderate category. The level of dental and oral hygiene of trimester I and II pregnant women includes moderate criteria with an average of 2.2, the status of gingivitis for first-trimester pregnant women (38.7%) who have moderate gingivitis, and trimester II has mild gingivitis (45, 2%). the frequency of brushing teeth twice a day but the time used is still not right and the average pregnant woman never uses dental floss. While gargling habits use more cold water, and for a balanced diet consume more acidic foods and pregnant women trimester I and II control the health of their teeth and mouth only when sick. It was concluded that the dental caries status of pregnant women trimester I and II included in the moderate category, the status of dental and oral hygiene criteria of moderate and gingivitis status of pregnant women for trimester I including moderate inflammation and trimester II mild inflammation, and maintenance of dental and oral health of pregnant women was not optimal because there are still many pregnant women who ignore oral and dental hygiene. Abstrak: Status Karies Gigi, Status Kebersihan Gigi dan Mulut dan Status Gingivitis Ibu Hamil Trimester I dan II. Kehamilan merupakan suatu peristiwa yang sering di jumpai dalam kehidupan seorang wanita, sebab wanita hamil merupakan salah satu kelompok yang rentan terhadap penyakit gigi dan mulut. Tujuan penelitian : untuk mengetahui status karies gigi, status kebersihan gigi dan mulut  dan status gingivitis ibu hamil trimester I dan II di Puskesmas Tarus Kabupaten Kupang. Metode penelitian yang digunakan adalah deskriptif. pengambilan sampel dengan teknik accidental sampling berjumlah 73 ibu hamil yang datang di Puskesmas Tarus. Hasil penelitian pada trimester I rata – rata ibu hamil mengalami 4 gigi berkaries termasuk kategori sedang, dan trimester II rata – rata ibu hamil mengalami 4 gigi berkaries termasuk kategori sedang. Tingkat kebersihan gigi dan mulut ibu hamil trimester I dan II termasuk kriteria sedang dengan rata – rata 2,2, status gingivitis ibu hamil trimester I sebanyak (38,7%) yang mengalami gingivitis sedang, dan trimester II mengalami gingivitis ringan sebanyak (45,2%). frekuensi menyikat gigi 2 kali sehari tetapi waktu yang digunakan masih belum tepat dan rata – rata ibu hamil tidak pernah menggunakan benang gigi. Sedangkan kebiasaan berkumur lebih banyak menggunakan air dingin, dan untuk diet seimbang lebih banyak mengkonsumsi makanan yang bersifat asam dan ibu hamil trimester I dan II mengontrol kesehatan gigi dan mulutnya hanya ketika sakit. Disimpulkan bahwa status karies gigi ibu hamil trimester I dan II termasuk kategori sedang, status kebersihan gigi dan mulut kriteria sedang dan status gingivitis ibu hamil untuk trimester I termasuk inflamasi sedang dan trimester II inflamasi ringan, serta pemeliharaan kesehatan gigi dan mulut ibu hamil belum maksimal karena masih banyak ibu hamil yang mengabaikan kebersihan gigi dan mulut.

Etiopathogenetic aspects of somatic dysfunction formation during pregnancy

2020 ◽  
pp. 41-53
Author(s):  
E. N. Nenashkina ◽  
Yu. P. Potekhina ◽  
E. S. Tregubova ◽  
V. O. Belash
Keyword(s):  
Pregnant Woman ◽  
Pregnant Women ◽  
Occurrence Frequency ◽  
Second Trimester ◽  
Third Trimester ◽  
Functional Changes ◽  
Pelvic Region ◽  
The Third ◽  
Somatic Dysfunction ◽  
Duration Of Pregnancy

Introduction. Changes occuring in a woman′s organism during pregnancy are genetically programmed and have a physiological adaptive character. The range of these changes affect all organism systems and is caused by the need to sustain the mother and the fetus; and the changes severity is causedby gestational age, number of fetuses and individual reserve possibilities of the motherorganism. The development of pregnancy is accompanied by a number of regular structural and functional changes in the woman′s organism, which in turn can serve as a background or cause for the formation of somatic dysfunctions, the level of manifestation and severity of which depend on the compensatory capabilities of the female organism.The goal of research was to study the occurrence frequency of somatic dysfunction in pregnant women at different stages of pregnancy and to compare it with anatomical and physiological changes in the woman′s organism.Materials and methods. It was examined 162 healthy pregnant women aged 25 to 45 years, with a gestation period of 7 to 37 weeks. The average age was 33±2,1 year, the proportion of the first-time mothers was 62 %. The distribution of women by trimester of pregnancy was as follows: I trimester — 42 people, II trimester — 60 people, III trimester — 60 people. There were no statistically significant differences in the age of the subjects in these three groups (p>0,05). The study lasted from February 2019 to March 2020. Each patient was examined by an osteopath during the initial treatment.Results. A statistically significant increase in the incidence of somatic dysfunctions (SD) of the thoracic region (p<0,05) and the pelvic region (p<0,001) was found from the first to the third trimester of pregnancy. SD of the lumbar region appeared only in the second trimester, and in the third trimester the occurrence frequency of these SD has not changed. It is these three regions that experience the most pronounced structural and functional changes, which are increasing with the pregnancy development. The most significant changes occur in the pelvic region, both in its structural component (bones, joints, muscles, ligaments) and in the visceral component (growing uterus). In addition, the most significant changes in blood and lymph circulation occur in the pelvic region. According to our observations, somatic dysfunctions of the pelvic region occurred in 7,1 % of the examined patients in the first trimester, in 25 % — in the second trimester, and in 63,3 % — in the third trimester. Among local SD, there is a statistically significant increase in the occurrence frequency of SD of the thoracic diaphragm, the pubic joint and impaired mobility of the uterus (p<0,01) with an increase in the duration of pregnancy, which is natural. As the size of the uterus increases, there is a decrease in the mobility of the thoracic diaphragm, which is most pronounced in the 3rd trimester. The pubic joint undergoes increasing stress and structural and functional restructuring as pregnancy progresses. There was a statistically significant difference (p<0,01) in the representation of dominant somatic dysfunctions depending on the duration of pregnancy, the predominance in the 3rd trimester of pregnancy in most women (63,3 %) of the dominant SD of the pelvic region.Conclusion. The functional changes occurring in the body of a pregnant woman have not only specific characteristics associated with the period of pregnancy, but also serve as a background condition that predisposes to the formation of specific somatic dysfunctions. As pregnancy progresses, the somatic dysfunctions of the pelvic and thoracic regions come to the fore; these SD are most likely associated with changes in the postural balance of a pregnant woman, due to changes in anatomically-topographic relationships due to the growth of the pregnant uterus. 

scholarly journals Spontaneous Intra-leiomyoma Hemorrhage during Second Trimester of Pregnancy

2020 ◽  
Vol 2 (6) ◽  
Author(s):  
Khong Jac Mun ◽  
Zalina Nusee ◽  
Riduan Tahar
Keyword(s):  
Abdominal Pain ◽  
Pregnant Woman ◽  
Pregnant Women ◽  
Uterine Fibroid ◽  
Conservative Management ◽  
Postpartum Period ◽  
Hypovolemic Shock ◽  
Second Trimester ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture

Uterine fibroid affects 0.3-2.6% of pregnant women and it is usually asymptomatic during pregnancy [1]. In about 10% of these patients will have complications such as miscarriage, fetal malpresentation, premature rupture of membranes, placenta abruptio, preterm delivery, abdominal pain due to fibroid torsion or degeneration [2]. Bleeding into the uterine fibroid is extremely rare and patient can present with acute abdomen [11]. Up to date, there were only two cases reported and both occur in postpartum period. We present a case of a pregnant woman with huge uterine fibroid with spontaneous intra-leiomyoma bleeding causing hypovolemic shock at 22 weeks of gestation. Because of failure of conservative management, we performed fibroid resection at 22 weeks of gestation with preservation of the pregnancy.

scholarly journals Status Karies Gigi, Status Kebersihan Gigi dan Mulut dan Status Gingivitis Ibu Hamil Trimester I dan II

2019 ◽  
Vol 1 (1) ◽  
pp. 28-38
Author(s):  
Paulena Fao Lei ◽  
Emma Krisyudhanti ◽  
Christina Ngadilah ◽  
Applonia Leo Obi
Keyword(s):  
Pregnant Woman ◽  
Dental Caries ◽  
Pregnant Women ◽  
Health Center ◽  
Oral Hygiene ◽  
Cold Water ◽  
First Trimester ◽  
Second Trimester ◽  
The Status ◽  
Carious Teeth

Abstract: Dental Caries Status, Status of Dental and Oral Hygiene and Gingivitis Status of Pregnant Women Trimester I and II. Pregnancy is an event that is often encountered in a woman's life because pregnant women are one group that is vulnerable to dental and oral diseases. The purpose of this study: to determine the status of dental caries, the status of dental and oral hygiene, and the status of gingivitis for first and second-trimester pregnant women in Tarus Health Center, Kupang Regency. The research method used is descriptive. sampling with an accidental sampling technique totaling 73 pregnant women who came to the health center Tarus. The results of the study in the first trimester - the average pregnant woman experienced 4 carious teeth included in the medium category, and the second trimester the average pregnant woman had 4 carious teeth including the moderate category. The level of dental and oral hygiene of trimester I and II pregnant women includes moderate criteria with an average of 2.2, the status of gingivitis for first-trimester pregnant women (38.7%) who have moderate gingivitis, and trimester II has mild gingivitis (45, 2%). the frequency of brushing teeth twice a day but the time used is still not right and the average pregnant woman never uses dental floss. While gargling habits use more cold water, and for a balanced diet consume more acidic foods and pregnant women trimester I and II control the health of their teeth and mouth only when sick. It was concluded that the dental caries status of pregnant women trimester I and II included in the moderate category, the status of dental and oral hygiene criteria of moderate and gingivitis status of pregnant women for trimester I including moderate inflammation and trimester II mild inflammation, and maintenance of dental and oral health of pregnant women was not optimal because there are still many pregnant women who ignore oral and dental hygiene. Abstrak: Status Karies Gigi, Status Kebersihan Gigi dan Mulut dan Status Gingivitis Ibu Hamil Trimester I dan II. Kehamilan merupakan suatu peristiwa yang sering di jumpai dalam kehidupan seorang wanita, sebab wanita hamil merupakan salah satu kelompok yang rentan terhadap penyakit gigi dan mulut. Tujuan penelitian : untuk mengetahui status karies gigi, status kebersihan gigi dan mulut  dan status gingivitis ibu hamil trimester I dan II di Puskesmas Tarus Kabupaten Kupang. Metode penelitian yang digunakan adalah deskriptif. pengambilan sampel dengan teknik accidental sampling berjumlah 73 ibu hamil yang datang di Puskesmas Tarus. Hasil penelitian pada trimester I rata – rata ibu hamil mengalami 4 gigi berkaries termasuk kategori sedang, dan trimester II rata – rata ibu hamil mengalami 4 gigi berkaries termasuk kategori sedang. Tingkat kebersihan gigi dan mulut ibu hamil trimester I dan II termasuk kriteria sedang dengan rata – rata 2,2, status gingivitis ibu hamil trimester I sebanyak (38,7%) yang mengalami gingivitis sedang, dan trimester II mengalami gingivitis ringan sebanyak (45,2%). frekuensi menyikat gigi 2 kali sehari tetapi waktu yang digunakan masih belum tepat dan rata – rata ibu hamil tidak pernah menggunakan benang gigi. Sedangkan kebiasaan berkumur lebih banyak menggunakan air dingin, dan untuk diet seimbang lebih banyak mengkonsumsi makanan yang bersifat asam dan ibu hamil trimester I dan II mengontrol kesehatan gigi dan mulutnya hanya ketika sakit. Disimpulkan bahwa status karies gigi ibu hamil trimester I dan II termasuk kategori sedang, status kebersihan gigi dan mulut kriteria sedang dan status gingivitis ibu hamil untuk trimester I termasuk inflamasi sedang dan trimester II inflamasi ringan, serta pemeliharaan kesehatan gigi dan mulut ibu hamil belum maksimal karena masih banyak ibu hamil yang mengabaikan kebersihan gigi dan mulut.

Clinical case of periostitis in pregnant women complicated by sepsis

2020 ◽  
pp. 61-63
Author(s):  
S. Sh. Kakvaeva ◽  
M. A. Magomedova ◽  
A. N. Dzhalilova
Keyword(s):  
Pregnant Woman ◽  
Multiple Organ Failure ◽  
Pregnant Women ◽  
Organ Failure ◽  
Clinical Case ◽  
Clinical Observation ◽  
Infectious Agent ◽  
Modern Medicine ◽  
Multiple Organ ◽  
Number Of Patients

One of the most serious problems of modern medicine is sepsis. The number of patients undergoing this complication is 20–30 million (WHO) annually and has no tendency to decrease. Sepsis is characterized by severe multiple organ failure due to a violation of the response of the macroorganism to an infectious agent. Moreover, it is dangerous with high mortality. Sepsis often develops in patients with immunodeficiency conditions, which primarily include pregnant women. The article presents a clinical observation of a case of periostitis in a pregnant woman complicated by a septic state.

Evaluation of the results of planned open surgical interventions in primary chronic vein disease in pregnant women

2020 ◽  
pp. 51-56
Author(s):  
V.М. Аntonyuk-Kysil ◽  
◽  
І.Y. Dziubanovskyi ◽  
V.М. Yenikeeva ◽  
S.І. Lichner ◽  
...  
Keyword(s):  
Pregnant Woman ◽  
Pregnant Women ◽  
Postoperative Period ◽  
Postpartum Period ◽  
Clinical Manifestations ◽  
Lower Extremities ◽  
Vascular Surgeon ◽  
Surgical Interventions ◽  
Perinatal Center ◽  
Vein Disease

The objective: to evaluate the results of planned open surgical interventions (POSI) in pregnant women with primary symptomatic chronic vein disease (PSCVD). Materials and methods. The study included 457 pregnant women operated on a routine basis with PSCVD. The patients underwent ultrasound duplex angioscanning (USDA) of the veins of the lower extremities, inguinal canals, and iliac veins. The severity of the clinical manifestations of PSCVD was evaluated on a VCSS scale. With the help of the circadian visual-analog scale, the dynamics after the operative pain were studied. The effect of POSI on uterine tone and cardiac function of the fetus was investigated using cardiotocography. When forming the results for POSI, data from USDA, the severity of clinical and cosmetic manifestations of PCVD, the need for active prevention of thrombophlebetic, thromboembolic and hemorrhagic complications, minimization of surgical childbirth were taken into account. The results of treatment were studied in 2 groups of patients. Patients of the first group were treated with conservative therapy, the second group – POSI. Parametric indicators, which were presented as mean and standard error M(SD), were used for statistical data processing of the study, and their reliability was estimated using Student’s t-test. The species was determined to be significant at p<0.05. Results. 495 POSI were performed at 28-38 weeks gestation in an obstetric hospital (perinatal center), by a vascular surgeon from the staff of the center, who was familiarized with the peculiarities of working with this contingent of patients. Surgery was performed under local anesthesia in 346 (75.49%) pregnant women at one extremity, in 111 (24.51%) – at two in one session. According to the results of the study, it was noted that in the first group 33.7% of patients had a positive clinical result due to the reduction of pain syndrome, while 67.5% of patients had an increase and spread of varicose transformation in the area of saphenous and/or non-saphenous veins with spread of pathological venous reflux in the distal direction. 78% of patients had the need to administer prophylactic doses of low molecular weight heparins, both during pregnancy and in postpartum period. Out of 126 pregnant women with pronounced varicose veins of the external genital organs and perineum in 36 (28.6%) deliveries were performed by caesarean section. In 9 (3%) patients there was an acute thrombophlebitis of the subcutaneous veins of the lower extremities, which required 5 pregnant women to undergo urgent surgery when the inflammatory process had spread to the middle and above along the femoral vein of the large subcutaneous vein. Pregnant women of the second group with PSCVD on the basis of obstetric hospital (perinatal center) POSI were performed in the organization, which laid the ideology of the FTS program, strictly individual indications for intervention in the optimal terms of pregnancy, multidisciplinary management of patients, due to this in 93% of operated patients regression of clinical manifestations of the disease was noted, whch contributed to the correct and safe delivery of pregnancy with 100% absence of preterm birth, abnormalities in fetal development, pregnancy course, negative impact on obstetric and somatic condition of the pregnant woman. No hemorrhagic, thrombophlebic, thromboembolic complications were noted. Patients in the postoperative period did not require medical support, as during the period of pregnancy, during delivery and in the postpartum period. There were no indications for surgical delivery. 2.4% of patients experienced complications of post-operative wounds in the form of cheese, which had no effect on pregnancy and was eliminated before delivery. In the postoperative period, if necessary, it was recommended to use elastic compression class garments 1–2. Conclusion. POSI made at PSCVD in optimal terms of pregnancy in a specialized obstetric hospital by a vascular surgeon in strictly individual indications is safe, both for the fetus and the pregnant woman. It is promising to further study the results of POSI in pregnant women with PSCVD to introduce it into the arsenal of treatment of this pathology. Key words: FTS ideology, planned open surgical interventions in pregnant women.

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