Trajectory Curves for Purposes of Benchmarking and Predicting Clinical Outcomes: A Scoping Review

Abstract Trajectory curves are valuable tools to benchmark patient health status and predict future outcomes. A longitudinal study is underway to examine social participation after burn injury using the Life Impact Burn Recovery Evaluation (LIBRE) Profile with the goal of developing trajectory curves for specific domains that focus on social re-integration. We conducted a scoping review to inform and understand trajectory curves applied in clinical settings to compare outcomes for an individual to a matched cohort of comparable patients or predicted expected outcomes over time. This scoping review utilized a PubMed search from January 2014 to August 2019 for the following terms: “trajectory curves” or “trajectory models” and “clinic” or “clinical.” Only articles that specifically referenced longitudinal and clinical research designs were included in the scoping review. Articles were assessed using standard scoping review methods and categorized based on clinical application of trajectory curves for either benchmarking or prediction. The initial literature review identified 141 manuscripts and 34 met initial inclusion criteria. The reviewed articles support the clinical use of trajectory curves. Findings provide insight into several key determinants involved with the successful development and implementation of trajectory curves in clinical settings. These findings will inform efforts to use the LIBRE Profile to model social participation recovery and assist in developing effective strategies using trajectory curves to promote social reintegration after burn injury.

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Social Participation of Burn Survivors and the General Population in Work and Employment: A Life Impact Burn Recovery Evaluation (LIBRE) Profile Study

Journal of Burn Care & Research ◽

10.1093/jbcr/irz076 ◽

2019 ◽

Vol 40 (5) ◽

pp. 669-677 ◽

Cited By ~ 1

Author(s):

Cayla J Saret ◽

Pengsheng Ni ◽

Molly Marino ◽

Emily Dore ◽

Colleen M Ryan ◽

...

Keyword(s):

General Population ◽

Posttraumatic Growth ◽

Social Participation ◽

Burn Injury ◽

Response Shift ◽

Sample Mean ◽

Burn Survivors ◽

Life Impact ◽

Work Integration ◽

Work And Employment

AbstractIntroductionWork integration and retention after burn injury is a key outcome. Little is known about how burn survivors reintegrate into the workplace. This article compares scores on the Life Impact Burn Recovery Evaluation (LIBRE) Profile, a burn-specific measure of social participation, between burn survivors and general population samples, focusing on the Work and Employment domain.MethodsConvenience samples of burn survivors and the U.S. population were obtained. Differences in demographic and clinical characteristics and LIBRE Profile scores were assessed. To examine work and employment, we compared family and friends, social activities, and social interactions scores among working vs nonworking burn survivors.ResultsSix hundred and one burn survivors (320 employed) and 2000 U.S. residents (1101 employed) were surveyed. The mean age (P = .06), distributions of sex (P = .35), and Hispanic ethnicity (P = .07) did not differ significantly. Distributions of race (P < .01) and education (P = .01) differed significantly. The burn survivor sample had higher scores, demonstrating higher participation, for work and employment (mean = 49.5, SD = 9.42) than the general sample (mean = 46.94, SD = 8.94; P < .0001), which persisted after adjusting for demographic characteristics. Scores on the three domains administered to all respondents were higher (P < .001) for working than nonworking burn survivors.ConclusionDistributions indicated higher social participation in the burn survivor sample than the general sample. Possible explanations include sample bias; resilience, posttraumatic growth, or response-shift of survivors; and limitations of using items in the general sample. Working burn survivors scored higher than those not working. Future work can explore factors that mediate higher scores and develop interventions.

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833 The Importance of Trajectory Curves for the Implementation of Outcome Benchmarks in a Clinical Setting

Journal of Burn Care & Research ◽

10.1093/jbcr/iraa024.406 ◽

2020 ◽

Vol 41 (Supplement_1) ◽

pp. S254-S255

Author(s):

Brian M Kelter ◽

Audrey E Wolfe ◽

Mary D Slavin ◽

Lewis Kazis ◽

Colleen M Ryan ◽

...

Keyword(s):

Risk Assessment ◽

Literature Review ◽

Social Participation ◽

Burn Injury ◽

Patient Specific ◽

Clinical Settings ◽

Patient Reported ◽

Burn Survivors ◽

Analytical Approaches ◽

Over Time

Abstract Introduction The creation of individualized treatment plans that address social participation in burn survivors requires an understanding of the expected changes over time from the original burn injury. The Life Impact Burn Recovery Evaluation (LIBRE) Profile is a patient-reported outcome measure for social participation after burn injury. Visual representation of expected change over time of a population is achieved through the development of trajectory curves (TCs), serving as benchmarks for recovery. In order to optimize the implementation of LIBRE Profile TCs, a literature review was conducted to examine utilization of TCs in other clinical settings. Methods A review of studies published from 2014–2019, demonstrating TCs as growth or treatment models in clinical settings, was performed. Literature was identified by searching “trajectory curves,” “trajectory models,” and “clinic” or “clinical” in PubMed. Articles focusing on three areas of inquiry were included: 1) measuring individual patient growth; 2) comparing progress for similar patient cohorts to provide contextualized reference for personal growth; 3) predictive medicine/risk assessment for interventional care in various conditions. Results The initial literature review identified 141 manuscripts. A total of 107 were excluded and 34 manuscripts were reviewed and categorized based on the three areas of inquiry (Figure 1; Table 1). Positive results from TCs in all areas of inquiry were noted in 22 of the 34 the chosen studies. General trends for each area of inquiry include: an increased ability for parents and clinicians to track individual patient progress in what was primarily anthropometric studies; articles relating to comparative cohort tracking show that trajectory-driven analytical approaches offer displays of progress across similar clinical groups of recovery for given conditions. Use of TCs in predictive care or risk assessment typically relate to acute conditions such as asthma, traumatic brain injury, or degenerative conditions (neurocognitive or musculoskeletal). For the most part, these diagnoses depict a positive trend for clinicians to identify future outcomes using fitted trajectories. Conclusions These findings support the clinical use of trajectory curves to present patient-specific, cohort-relative, and predictive treatment for outcome-based results post-burn for burn survivors. Applicability of Research to Practice Future research will assess the use of LIBRE Profile recovery trajectories as benchmarks for optimization of social participation outcomes.

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Patient Health Status Following the Recovery from Burn Injury

Journal of Burn Care & Rehabilitation ◽

10.1097/00004630-200001001-00224 ◽

2000 ◽

Vol 21 ◽

pp. S246

Author(s):

J. Pulito ◽

L. Staul ◽

S. Christie

Keyword(s):

Health Status ◽

Burn Injury ◽

Patient Health Status ◽

Patient Health

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Interpreting Life Impact Burn Recovery Evaluation Profile Scores for Use by Clinicians, Burn Survivors, and Researchers

Journal of Burn Care & Research ◽

10.1093/jbcr/iraa100 ◽

2020 ◽

Author(s):

Mary D Slavin ◽

Colleen M Ryan ◽

Jeffrey C Schneider ◽

Amy Acton ◽

Flor Amaya ◽

...

Keyword(s):

Social Participation ◽

Burn Injury ◽

Sexual Relationships ◽

Cut Points ◽

Delphi Approach ◽

Patient Reported ◽

Burn Survivors ◽

Life Impact ◽

Four Levels ◽

Different Levels

Abstract The Life Impact Burn Recovery Evaluation (LIBRE) Profile is a patient-reported outcome measure developed to assess social participation in adult burn survivors. This study identified numeric score cut-points that define different levels of social participation ability and described each level. An expert panel identified numeric score cut-points that distinguish different levels of social participation for the six LIBRE Profile domains. Methods employed an iterative, modified-Delphi approach, and bookmarking to review calibrated item banks. Analyses (using calibration sample data and repeated in a validation sample) examined means, SDs, and sample distributions for each level. Analyses of variance examined score differences between levels. The panel developed descriptions for each established level. Initial cut-points resulted in four levels for five domains (Social Activities, Social Interactions, Romantic Relationships, Sexual Relationships, and Work & Employment) and five levels for the sixth domain (Relationships with Family & Friends). Comparisons demonstrated significant differences between level mean scores for all domains (P < .05) except Relationships with Family & Friends. Based on follow-up surveys, Relationships with Family & Friends score cut-points were adjusted to identify four levels with significant score differences between all levels. Panelists reached consensus for level descriptions. Score cut-points and descriptions identify different levels of social participation, providing a relevant context for interpreting LIBRE Profile numeric scores. LIBRE Profile Social Participation levels will help clinicians and persons with burn injury interpret LIBRE Profile numeric scores and promote use of this important new assessment.

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PATIENT HEALTH STATUS TRAJECTORIES IN HEART FAILURE WITH RECOVERED EJECTION FRACTION

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(19)31577-3 ◽

2019 ◽

Vol 73 (9) ◽

pp. 970

Author(s):

Peter Wohlfahrt ◽

Jose Nativi-Nicolau ◽

Mingyuan Zhang ◽

Craig Selzman ◽

Tom Greene ◽

...

Keyword(s):

Heart Failure ◽

Health Status ◽

Ejection Fraction ◽

Patient Health Status ◽

Patient Health

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Peritoneal Dialysis: A Scoping Review of Strategies to Maximize pd Utilization

Peritoneal Dialysis International ◽

10.3747/pdi.2016.00057 ◽

2017 ◽

Vol 37 (2) ◽

pp. 159-164 ◽

Cited By ~ 9

Author(s):

Bikaramjit S. Mann ◽

Braden J. Manns ◽

Lianne Barnieh ◽

Matthew J. Oliver ◽

Daniel Devoe ◽

...

Keyword(s):

Peritoneal Dialysis ◽

Scoping Review ◽

Controlled Trials ◽

Effective Strategies ◽

Online Databases ◽

Unpublished Studies ◽

Cochrane Database ◽

Stage Renal Disease ◽

End Stage ◽

Effective Use

The percentage of end-stage renal disease (ESRD) patients treated with peritoneal dialysis (PD) has declined in many countries since the mid-1990s. Barriers to PD have been reviewed extensively in the literature, but evidence about strategies to address these barriers and maximize the safe and effective use of PD is lacking. We therefore decided to conduct a scoping review identifying strategies to maximize PD use in adults with ESRD. Our search strategy included the following online databases: MEDLINE (OVID), EMBASE, PubMed, Cochrane Controlled Trials Register, Current Controlled Trials, and Cochrane Database of Systematic Reviews for articles published from 1974 to November 2013. Experts in the field were contacted for information about other ongoing or unpublished studies. A complementary search was conducted in the gray literature. Websites of national, provincial or regional agencies were searched for documents regarding policies surrounding the use of PD. Individual dialysis centers need to identify barriers to increasing PD in their program and direct targeted strategies to maximize PD utilization. Our review highlights some effective strategies that may be used. Our review also highlights the need for further research into strategies to maximize PD utilization.

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Information and communication technology-based interventions for suicide prevention implemented in clinical settings: A scoping review protocol

10.31219/osf.io/7csgp ◽

2021 ◽

Author(s):

Hwayeon Danielle Shin ◽

Juveria Zaheer ◽

Terri Rodak ◽

John Torous ◽

Gillian Strudwick

Keyword(s):

Information And Communication Technology ◽

Suicide Prevention ◽

Communication Technology ◽

Scoping Review ◽

Implementation Strategies ◽

Mobile App ◽

Barriers And Facilitators ◽

Clinical Settings ◽

Scoping Reviews ◽

Information And Communication

IntroductionThere is a surplus of Information and Communication Technology (ICT)-based interventions for suicide prevention. However, it is unclear which of these ICT-based interventions for suicide prevention have been implemented in clinical settings. Furthermore, evidence shows that implementation strategies have often been mismatched to existing barriers. In response, the authors recognize the critical need for prospectively assessing the barriers and facilitators and then strategically developing implementation strategies. This review is part of a multi-phase project to develop and test tailored implementation strategies for mobile app-based suicide prevention in clinical settings. The overall objective of this scoping review is to identify and characterize ICT-based interventions for all levels of suicide prevention in clinical settings. Additionally, this review will identify and characterize the barriers and facilitators to implementing these ICT-based interventions as well as reported measures and outcomes. The findings will directly inform the subsequent phase to maximize implementation and inform future efforts for implementing other types of ICT-based interventions related to suicide prevention in clinical settings.Methods and analysis This review will adhere to the methods described by the Joanna Briggs Institute for conducting scoping reviews. The reporting will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for scoping reviews checklist. The following databases will be searched: Medline, PsycInfo, Embase, CINAHL, Web of Science, and LISTA. Two reviewers will independently screen the articles and extract data using a standardised data collection tool. Then, authors will characterize extracted data using frameworks, typology, and taxonomies to address the proposed review questions. Ethics and disseminationEthics approval is not required for this scoping review. Authors will share the results in a peer-reviewed, open access publication, and conference presentations. Furthermore, the findings will be shared with relevant health organizations through lay language summaries and informal presentations.

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Biological-Signal-Based User-Interface System for Virtual-Reality Applications for Healthcare

Journal of Sensors ◽

10.1155/2018/9054758 ◽

2018 ◽

Vol 2018 ◽

pp. 1-10

Author(s):

Sang Hun Nam ◽

Ji Yong Lee ◽

Jung Yoon Kim

Keyword(s):

Virtual Reality ◽

User Interface ◽

Virtual Reality Technology ◽

Biological Signal ◽

Patient Health Status ◽

Interface System ◽

Biological Signals ◽

Patient Health ◽

System Module ◽

Tracking Device

Biosignal interfaces provide important data that reveal the physical status of a user, and they are used in the medical field for patient health status monitoring, medical automation, or rehabilitation services. Biosignals can be used in developing new contents, in conjunction with virtual reality, and are important factors for extracting user emotion or measuring user experience. A biological-signal-based user-interface system composed of sensor devices, a user-interface system, and an application that can extract biological-signal data from multiple biological-signal devices and be used by content developers was designed. A network-based protocol was used for unconstrained use of the device so that the biological signals can be freely received via USB, Bluetooth, WiFi, and an internal system module. A system that can extract biological-signal data from multiple biological-signal data and simultaneously extract and analyze the data from a virtual-reality-specific eye-tracking device was developed so that users who develop healthcare contents based on virtual-reality technology can easily use the biological signals.

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