Human gnathostomiasis in Sri Lanka: An underreported disease?

2021 ◽  
Author(s):  
Stefano Musumeci ◽  
Juliette Besson ◽  
Andrea Allgöwer ◽  
François Chappuis
Keyword(s):  
Sri Lanka ◽  
Western Blot ◽  
Laboratory Tests ◽  
University Hospital ◽  
Left Forearm ◽  
History Of ◽  
The University

Highlight A healthy young man from Sri Lanka, currently living in Switzerland, consulted at the University Hospital of Geneva with a history of painful erythema and swelling of the left forearm. Laboratory tests showed a slight eosinophilia. Western blot serology for Gnathostoma spp, inconclusive at presentation, became positive two weeks later.

scholarly journals Discovery and Further Studies on Giant Viruses at the IHU Mediterranee Infection That Modified the Perception of the Virosphere

Viruses ◽  
2019 ◽  
Vol 11 (4) ◽  
pp. 312 ◽  
Author(s):  
Clara Rolland ◽  
Julien Andreani ◽  
Amina Louazani ◽  
Sarah Aherfi ◽  
Rania Francis ◽  
...  
Keyword(s):  
University Hospital ◽  
Defense System ◽  
Genomic Complexity ◽  
Number Of Genes ◽  
History Of ◽  
Giant Viruses ◽  
The University ◽  
Acanthamoeba Polyphaga Mimivirus ◽  
Active Contribution

The history of giant viruses began in 2003 with the identification of Acanthamoeba polyphaga mimivirus. Since then, giant viruses of amoeba enlightened an unknown part of the viral world, and every discovery and characterization of a new giant virus modifies our perception of the virosphere. This notably includes their exceptional virion sizes from 200 nm to 2 µm and their genomic complexity with length, number of genes, and functions such as translational components never seen before. Even more surprising, Mimivirus possesses a unique mobilome composed of virophages, transpovirons, and a defense system against virophages named Mimivirus virophage resistance element (MIMIVIRE). From the discovery and isolation of new giant viruses to their possible roles in humans, this review shows the active contribution of the University Hospital Institute (IHU) Mediterranee Infection to the growing knowledge of the giant viruses’ field.

Single Centre Experience in Patients with Primary Hyperparathyroidism: Sporadic, Lithium-associated and in Multiple Endocrine Neoplasia

2019 ◽  
Vol 128 (10) ◽  
pp. 693-698
Author(s):  
Sabine Dillenberger ◽  
Detlef K. Bartsch ◽  
Elisabeth Maurer ◽  
Peter Herbert Kann
Keyword(s):  
Primary Hyperparathyroidism ◽  
Multiple Endocrine Neoplasia ◽  
University Hospital ◽  
Primary Surgery ◽  
Endocrine Neoplasia ◽  
Single Centre Experience ◽  
Significant Difference ◽  
History Of ◽  
The University

Abstract Purpose It is assumed that primary hyperparathyroidism (pHPT) in Multiple Endocrine Neoplasia (MEN) and lithium-associated pHPT (LIHPT) are associated with multiple gland disease (MGD), persistence and recurrence. The studies purpose was to determine frequencies, clinical presentation and outcome of sporadic pHPT (spHPT), LIHPT and pHPT in MEN. Additional main outcome measures were the rates of MGD and persistence/recurrence. Methods Retrospective analysis of medical records of 682 patients with pHPT who had attended the University Hospital of Marburg between 01–01–2004 and 30–06–2013. All patients were sent a questionnaire asking about their history of lithium medication. Results Out of 682 patients, 557 underwent primary surgery (532 spHPT, 5 LIHPT, 20 MEN), 38 redo-surgery (31 spHPT, 7 MEN), 55 were in follow-up due to previous surgery (16 spHPT, 1 LIHPT, 38 MEN) and 37 were not operated (33 spHPT, 1 LIHPT, 3 MEN). Primary surgeries were successful in 97.4%, revealed singular adenomas in 92.4%, double adenomas in 2.9% and MGD in 3.4% of the cases. Rates of MGD in MEN1 (82.35%) were significantly higher than in spHPT (3.8%), while there was no significant difference between LIHPT (20%) and spHPT. Rates of persistence/recurrence did not significantly differ due to type of surgery (bilateral/unilateral) or type of HPT (spHPT/LIHPT/MEN). Conclusions History of lithium medication is rare among pHPT patients. While MGD is common in MEN1, rates of MGD, persistence or recurrence in LIHPT were not significantly higher than in spHPT.

scholarly journals Epidemiological and diagnostic aspects of spontaneous miscarriage in the department of gynecology-obstetric of the university hospital of Treichville in Abidjan

2020 ◽  
Vol 10 (1) ◽  
pp. 1
Author(s):  
Ignace N. Yao ◽  
Jean Marc L. Dia ◽  
Michelle M. Menin ◽  
Mouhedeen A. Oyelade ◽  
Corneille T. Saki ◽  
...  
Keyword(s):  
Chromosomal Abnormalities ◽  
Cross Sectional Study ◽  
University Teaching ◽  
University Hospital ◽  
Pathological Examination ◽  
Hiv Positive ◽  
Cross Sectional ◽  
History Of ◽  
Early Miscarriage ◽  
The University

Background: Describe the epidemiological and diagnostic of spontaneous aspects of early miscarriage in the department of the Gynecology Obsteric of Treichville University Teaching Hospital of   Treichville in Abidjan.Methods: A cross-sectional study was performed from January 2016 to March 2017 on patients received for an early miscarriage (gestational age less than 14 weeks of amenorrhea).Results: We recorded 337 cases of miscarriage and it shows that miscarriage was frequently estimated at 58 percent. Our patients had a average age of 32.9 years, 60.4 percent of them with primary education and 48 percent are housewives. The patients were paucigestes in 46 percent and the majority of them were nulliparous (62 percent). 6 percent with history of high blood pressure; diabetes (3 percent) and 31 percent of patients were HIV positive. Patients had pelvic pain at the admission in (55 percent). A miscarriage appears before 10 weeks of amenorrhea (76.1 percent) of cases. Ultrasound showed ovular debris (47 percent) of patients and (55.4 percent) were chromosomal abnormalities on anatomy-pathological examination.Conclusions: Spontaneous abortions are common and pathological examination is essential for diagnosis.

Neurosurgery at the University Hospital of North Norway: The History of the Northernmost Neurosurgical Department in the World

Neurosurgery ◽  
2003 ◽  
Vol 53 (3) ◽  
pp. 731-742 ◽  
Author(s):  
Tor Ingebrigtsen ◽  
Bertil Romner ◽  
Tore Solberg ◽  
Øystein P. Nygaard
Keyword(s):  
University Hospital ◽  
Neurosurgical Department ◽  
The World ◽  
History Of ◽  
The University ◽  
North Norway

Beneficial Effect of Acupuncture on Adult Patients with Asthma Bronchiale

1993 ◽  
Vol 21 (02) ◽  
pp. 113-117 ◽  
Author(s):  
W. Zwölfer ◽  
W. Keznickl-Hillebrand ◽  
A. Spacek ◽  
M. Cartellieri ◽  
G. Grubhofer
Keyword(s):  
Intensive Care ◽  
Retrospective Study ◽  
Beneficial Effect ◽  
Asthma Bronchiale ◽  
Acupuncture Treatment ◽  
Adult Patients ◽  
University Hospital ◽  
Outpatient Unit ◽  
History Of ◽  
The University

In a retrospective study 17 patients with long-standing history of asthma bronchiale were treated with acupuncture at the outpatient unit of the Department of Anaesthesia and Intensive Care in the University Hospital of Vienna. The subjective effectiveness of the treatment was determined using a standard questionnaire, which was sent to the patients' homes half a year after starting acupuncture treatment. Over 70% of our patients reported a significant improvement of their ailments after ten weeks of treatment as well as half a year after starting acupuncture.

Ventilator-Associated Pneumonia: Incidence and risk factors six intensive care units in Tunisia

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
A Ben Cheikh ◽  
S Bhiri ◽  
N ketaka ◽  
A Gara ◽  
S Khefacha ◽  
...  
Keyword(s):  
Risk Factors ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
University Hospital ◽  
Ventilator Associated Pneumonia ◽  
Factors Associated ◽  
History Of ◽  
Independent Risk Factors ◽  
The University ◽  
Very High

Abstract Background Ventilator-Associated Pneumonia (VAP) continues to cause significant morbidity, mortality, and hospital costs, especially in the intensive care unit (ICU). This study aimed to determine incidence and factors associated with VAP in six ICUs of the University Hospital-Sahloul (Sousse, Tunisia) in 2018. Methods We conducted a prospective observational cohort study over a three months period in six ICUs of the University Hospital-Sahloul (Sousse, Tunisia) in 2018. All patients hospitalized with mechanical ventilation (MV) for more than 48 hours in the ICUs were included. Logistic regression with the stepwise method of Hosmer and Lemeshow was used to identify factors associated with VAP. Results Overall, 110 patients were enrolled. The mean age of patients was 44 ± 25 years. Of them, 66.4% were male. The median duration of MV was 5 days [2-16]. The incidence of VAP was 32% and the density incidence was 33/1000 ventilator days. The most common organism were Pseudomonas aeruginosa (n = 14). Of them, 12 were ceftazidime-resistant and thee were resistant to imipenem. Independent risk factors associated with VAP in ICU were history of antibiotic therapy during last 6 months (p = 0.007), tracheotomy (p < 0.001) and reintubation (p < 0.001). Conclusions VAP rates in our ICUs were very high. Antimicrobial stewardship programs involving pharmacists and physicians must be elaborated to optimize the antibiotic prescribing. Mechanical ventilation require more-effective interventions control in our hospital. Key messages Ventilator-Associated Pneumonia rates were very high. Independent risk factors associated with Ventilator-Associated Pneumonia were history of antibiotic therapy during last 6 months, tracheotomy and reintubation.

scholarly journals Associated factors with otitis externa in the city of Antsiranana, Madagascar

2020 ◽  
Vol 6 (5) ◽  
pp. 810
Author(s):  
Patrick M. Randrianandraina ◽  
Mamy J. J. Razafimahatratra ◽  
Corinne E. Solo ◽  
Angelo H. Valisoa ◽  
Nathalie C. Razay ◽  
...  
Keyword(s):  
Medical Practice ◽  
Otitis Externa ◽  
Protective Factor ◽  
University Hospital ◽  
Contributing Factors ◽  
Cotton Swab ◽  
History Of ◽  
Exposure Ratio ◽  
The University ◽  
The City

<p class="abstract"><strong>Background:</strong> Otitis externa is common in medical practice. This study aims to identify the contributing factors of otitis externa in the city of Antsiranana, Madagascar.</p><p class="abstract"><strong>Methods:</strong> This is an analytical case-control type study, concerning patients with otitis externa, seen from January to July 2019, at the university hospital of place Kabary and at the grand Pavois medical practice, all in Antsiranana. The epidemiological, behavioural and clinical parameters were evaluated.  </p><p class="abstract"><strong>Results:</strong> We included 153 patients, among which 51were cases and 102 controls. The average age was 32.9 years (±19.41). The occurrence of otitis externa was significantly associated with the existence of a history of otitis externa, as well as ear cleaning 4 to 6 times per week (p=0.00; OR=46.17; CI=5.90-361.02). The diabetes exposure ratio was 18.79 in the ‘cases’ (p=0.00; CI=2.27-154.88), this ratio was 10.71 in the event of repeated swimming in pool (p=0.00; CI=2.22-51.70), 3.94 in case of ear cleaning with the cotton swab (p=00; CI=1.34-11, 60), and 2.23 when using headphones (p=0.02; CI=1.05-4.75).  The treatment of a previous otological pathology was a protective factor against otitis externa (OR=0.1500, p=0.0159, CI=0.0259-0.8689).</p><p class="abstract"><strong>Conclusions:</strong> The occurrence of otitis externa is related to well define daily behaviours and to other associated clinical factors. Managing these risk factors is the first step in treatment of otitis externa.</p>

Hygiene hypothesis and occupational asthma to vegetable textile dusts: A pilot study

2021 ◽  
Vol 17 ◽  
Author(s):  
Chayma Sridi ◽  
Maher Maoua ◽  
Imene Kacem ◽  
Imene Jammeli ◽  
Asma Chouchane ◽  
...  
Keyword(s):  
Occupational Asthma ◽  
Viral Infections ◽  
Allergic Diseases ◽  
Hygiene Hypothesis ◽  
University Hospital ◽  
Case Group ◽  
Low Socioeconomic ◽  
History Of ◽  
And Gender ◽  
The University

Background: Over the last decades, the prevalence of allergic manifestations has increased significantly. To explain the increase in the prevalence of asthma, Strachan advanced the Hygiene Hypothesis, which states that decreased exposure to infectious microorganisms in infancy may have contributed to changes in the maturation of the immune system during childhood. To the best of our knowledge, no analytical studies detailing the links between the Hygiene Hypothesis and occupational allergy have been carried out to date. Objective: To study the relations between the factors involved in the Hygiene Hypothesis and the occurrence of occupational asthma (OA) to vegetable textile dusts. Methods: A case-control study was conducted from September 2017 to September 2018. The cases and controls were enrolled from the occupational medicine department of the University Hospital “Farhat Hached” of Sousse (Tunisia) among patients attending from 2009 to 2016. The case group was composed of patients diagnosed with OA to vegetable textile dusts. Controls were age and gender matched, working in the textile sector and not suffering from any allergic diseases. Results: A total of 57 OA cases and 112 controls were enrolled. Four factors involved in the Hygiene Hypothesis were independently associated with OA to vegetable textile dusts: the lowest rank in siblings (p=0.037; ORa=0.14; 95% CI= [0.02-0.90]); contact with animals (p=0.006; ORa=0.22; 95% CI= [0.08-0.65]) especially cats; history of parasitic and/or mycotic infections in childhood (p=0.004; ORa=0.035; 95% CI= [0.004-0.35]) and history of viral infections in childhood (p<10-3; ORa=0.028; 95% CI= [0.01-0.14]). Other factors had a protective effect, such as the parents' low socioeconomic level and the father's occupation as a farmer. Conclusion: The microorganism-rich environment during childhood is an important model for understanding the mechanisms involved in the development of allergic asthma. Our data suggest that prevention of OA in adults might require early intervention in childhood.

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