The international and national challenges faced in ensuring prudent use of antibiotics

2016 ◽  
Author(s):  
Susan Hopkins
Keyword(s):  
World Health ◽  
Public Health Issue ◽  
Resistant Bacteria ◽  
Healthcare Organizations ◽  
Antibiotic Resistant ◽  
The Public ◽  
The World ◽  
New Antibiotics ◽  
Minor Injuries ◽  
Health Organization

In April 2014, the World Health Organization reinforced that without urgent coordinated action by most stakeholders the world is headed for a post-antibiotic era in which common infections and minor injuries, which have been treatable for decades, could kill once again. With the rise in the number of infections due to antibiotic-resistant bacteria and the lack of development of new antibiotics, antimicrobial resistance is a major clinical and public health issue that society needs to tackle. This chapter focuses on the challenges of drug resistance and antimicrobial development together with how healthcare organizations can address this threat. A number of initiatives are discussed, including how prescribers and the public need to ensure that antimicrobials are used widely to prevent any collateral damage.

scholarly journals Antibiotic Pipeline Coordinators

2018 ◽  
Vol 46 (S1) ◽  
pp. 25-31 ◽  
Author(s):  
Enrico Baraldi ◽  
Olof Lindahl ◽  
Miloje Savic ◽  
David Findlay ◽  
Christine Årdal
Keyword(s):  
Research And Development ◽  
World Health ◽  
Resistant Bacteria ◽  
Antibiotic Resistant ◽  
Priority List ◽  
Non Profit ◽  
Global Priority ◽  
The World ◽  
New Antibiotics ◽  
Health Organization

The World Health Organization (WHO) has published a global priority list of antibiotic-resistant bacteria to guide research and development (R&D) of new antibiotics. Every pathogen on this list requires R&D activity, but some are more attractive for private sector investments, as evidenced by the current antibacterial pipeline. A “pipeline coordinator” is a governmental/non-profit organization that closely tracks the antibacterial pipeline and actively supports R&D across all priority pathogens employing new financing tools.

scholarly journals Multidrug-Resistant Bacteria Isolated from Different Aquatic Environments in the North of Spain and South of France

2020 ◽  
Vol 8 (9) ◽  
pp. 1425
Author(s):  
Lara Pérez-Etayo ◽  
David González ◽  
José Leiva ◽  
Ana Isabel Vitas
Keyword(s):  
Wastewater Treatment Plants ◽  
Multidrug Resistant ◽  
World Health ◽  
Resistant Bacteria ◽  
Aquatic Environments ◽  
Multidrug Resistant Bacteria ◽  
Antibiotic Resistant ◽  
The North ◽  
New Antibiotics ◽  
Health Organization

Due to the global progress of antimicrobial resistance, the World Health Organization (WHO) published the list of the antibiotic-resistant “priority pathogens” in order to promote research and development of new antibiotics to the families of bacteria that cause severe and often deadly infections. In the framework of the One Health approach, the surveillance of these pathogens in different environments should be implemented in order to analyze their spread and the potential risk of transmission of antibiotic resistances by food and water. Therefore, the objective of this work was to determine the presence of high and critical priority pathogens included in the aforementioned list in different aquatic environments in the POCTEFA area (North Spain–South France). In addition to these pathogens, detection of colistin-resistant Enterobacteriaceae was included due its relevance as being the antibiotic of choice to treat infections caused by multidrug resistant bacteria (MDR). From the total of 80 analyzed samples, 100% of the wastewater treatment plants (WWTPs) and collectors (from hospitals and slaughterhouses) and 96.4% of the rivers, carried antibiotic resistant bacteria (ARB) against the tested antibiotics. Fifty-five (17.7%) of the isolates were identified as target microorganisms (high and critical priority pathogens of WHO list) and 58.2% (n = 32) of them came from WWTPs and collectors. Phenotypic and genotypic characterization showed that 96.4% were MDR and resistance to penicillins/cephalosporins was the most widespread. The presence of bla genes, KPC-type carbapenemases, mcr-1 and vanB genes has been confirmed. In summary, the presence of clinically relevant MDR bacteria in the studied aquatic environments demonstrates the need to improve surveillance and treatments of wastewaters from slaughterhouses, hospitals and WWTPs, in order to minimize the dispersion of resistance through the effluents of these areas.

scholarly journals Building evidence on what works (and what does not): practical guidance from the World Health Organization on post-project evaluation of adolescent sexual and reproductive health projects

2021 ◽  
Author(s):  
Susan Igras ◽  
Marina Plesons ◽  
Venkatraman Chandra-Mouli
Keyword(s):  
Reproductive Health ◽  
World Health Organization ◽  
Sexual And Reproductive Health ◽  
Project Evaluation ◽  
World Health ◽  
The Public ◽  
What Works ◽  
The World ◽  
Practical Guidance ◽  
Health Organization

Abstract Over the past 25 years, there has been significant progress in increasing the recognition of, resources for, and action on adolescent health, and adolescent sexual and reproductive health (ASRH) in particular. As with numerous other health areas, however, many of the projects that aim to improve ASRH are implemented without well-thought-out plans for evaluation. As a result, the lessons that projects learn as they encounter and address policy and programmatic challenges are often not extracted and placed in the public arena. In such cases, post-project evaluation (PPE) offers the possibility to generate learnings about what works (and does not work), to complement prospective studies of new or follow-on projects. To fill the gap in the literature and guidance on PPE, the World Health Organization developed The project has ended, but we can still learn from it! Practical guidance for conducting post-project evaluations of adolescent sexual and reproductive health projects. This article provides an overview of the guidance by outlining key methodological and contextual challenges in conducting PPE, as well as illustrative solutions for responding to them.

scholarly journals Deafening silence on a vital issue: The World Health Organization has ignored the sexuality of persons with disabilities

2018 ◽  
Vol 7 ◽  
Author(s):  
Christine Peta
Keyword(s):  
World Health Organization ◽  
Well Being ◽  
World Health ◽  
Human Beings ◽  
Persons With Disabilities ◽  
The Public ◽  
National Priority ◽  
Social Welfare System ◽  
The World ◽  
Health Organization

In 2016, the World Health Organization, through the Global Cooperation on Assistive Technology Initiative, issued the Priority Assistive Products List which is meant to be a guide to member states of the 50 assistive products needed for a basic health care and/or social welfare system; it is also a model from which nations can develop their national priority assistive products lists. The aim of this opinion paper is to share my views about the Priority Assistive Products List on the grounds that it makes no distinct mention of sexual assistive devices, yet research has indicated that sexuality is an area of great concern for persons with disabilities. In any case, sexuality forms a core part of being human, and it impacts on both the physical and mental well-being of all human beings. I conclude in part that, in its present format, the list perpetuates the myth that persons with disabilities are asexual beings who are innocent of sexual thoughts, feelings and experiences. The list also propagates the stereotype that sexuality is a sacred, private, bedroom matter that should be kept out of the public domain, to the detriment of the health and well-being of persons with disabilities.

scholarly journals Peter Chew Formular for calculate Covid-19 Vaccine efficiency

2021 ◽  
Author(s):  
Peter chew
Keyword(s):  
Relative Risk ◽  
New England ◽  
Target Population ◽  
World Health ◽  
Medical Worker ◽  
The Public ◽  
1 Peter ◽  
The World ◽  
Before And After ◽  
Health Organization

Abstract Background: The World Health Organization (WHO) said the situation in India was a "devastating reminder" of what the coronavirus could do. India shifts from mass vaccine exporter to importer, worrying the world. Every country needs to vaccinate its citizens faster, vaccination can reduce viral load. This results in vaccination that can reduce transmission, preventing serious illness and death'. Therefore, Countries with higher levels of vaccination can prevent them from becoming "Second India".Preprint study, Vaccination Education App (1). [Peter Chew, 2021] shows that most people do not take the covid-19 vaccine because they question the safety and effectiveness of the vaccine. Therefore, it is important to create a simple formula for calculate the efficiency of the covid-19 vaccine. The purpose of creating this calculation formula is to allow the public to calculate the efficiency of the covid-19 vaccine by themselves, so that they can understand the effectiveness of the vaccine and decide to take the vaccine. This helps to get a high response to COVID vaccinationMethods: Use the Data publish at The New England JOURNAL of MEDICINE, Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine [Fernando P. Polack et all , 2020]. Calculate of Pfizer BioNTech’s COVID-19 vaccine efficiency by using normal formular and Peter Chew Formular , show that the same result are obtain, which is 95.0599 %. In addition, By using public news information, the public can use the Peter Chew formula to easily calculate Covid-19 vaccine efficacy. This is to ensure public can do the calculation themselves. A calculation of relative risk is also provided to provide more information to persuade the public to take the vaccine.Results: The efficiency of Pfizer BioNTech's COVID-19 vaccine for Malaysian medical worker calculated by using the Peter Chew formula is 95.0599 %. In addition, the calculation of Peter Chew's formula also shows that before the vaccination, about 12 medical staff were infected every day, but after the full vaccination, only about one medical worker was infected every two days. The calculation of relative risk can also make it easier for the public to know that people who are not vaccinated with Pfizer BioNTech's COVID-19 vaccine are 22 times more likely to be infected than people who are fully vaccinated. The above results can convince those who easily question the effectiveness of vaccination.Conclusions: Peter Chew Formular easy to calculate, and the data required for the Peter Chew Formular calculation easy to obtain from public news. This is to ensure that the public can calculate the efficacy of the vaccine by themselves. The information on the calculation can let public compare the average target group get infected every day before and after fully vaccination is also an advantage to let public know the effectiveness of vaccination. One of the advantage of Peter Chew formulator is that we can assume a high target population of vaccination with k = 100, such as the medical worker group When k = 100, the Peter Chew formular calculation becomes very simple. The Proof of Peter Chew Formular must also be shown.

scholarly journals European Immunization Week 2008: Progress towards regional goals

2008 ◽  
Vol 13 (16) ◽  
Author(s):  
Collective WHO
Keyword(s):  
World Health Organization ◽  
Public Awareness ◽  
Political Support ◽  
World Health ◽  
Childhood Immunisation ◽  
Regional Office ◽  
The Public ◽  
National Immunisation ◽  
The World ◽  
Health Organization

The World Health Organization (WHO) Regional Office for Europe established the European Immunization Week (EIW, http://www.euro.who.int/vaccine) in 2005 for three reasons: 1) to raise public awareness of the benefits of immunisation, 2) to support national immunisation systems, and 3) to provide a framework for mobilising public and political support for governmental efforts to protect the public through universal childhood immunisation.

Effectiveness of a Lockdown Policy During a Global Pandemic

2021 ◽  
Vol 01 ◽  
Author(s):  
Yung Chin Shih
Keyword(s):  
Mathematical Modeling ◽  
Input Data ◽  
World Health ◽  
The Public ◽  
Public Managers ◽  
Global Pandemic ◽  
The World ◽  
Expected Benefits ◽  
Simultaneous Loss ◽  
Health Organization

Background: In 2019, when the World Health Organization (WHO) declared COVID-19 (Coronavirus 2019) a pandemic, many of the public managers faced tough situations in their cities due to the simultaneous loss of lives and jobs. In this regard, this study aims to propose a concise model that considers variables like the number of deaths, lethality of the virus, number of jobs and taxes collected by city halls, among others. Our study considers these issues in providing a relevant response and consistent answer to deliberations on the way forward. Method: Mathematical modeling was used to analyze the interaction between the agents involved and computer simulation was chosen to collect results. Results: - Changing the lockdown level (fixed and variable), the results of number of death per week, total number of unemployed, cost of companies and so on are shown. - The results show that for the input data considered, the 0% lockdown (LD) policy is more effective for the economy and tax collection and also succeeds in repressing the effects on the number of deaths. Because of it, the comparison between with pandemic and without pandemic is provided (in percentage). Conclusion: This study shows that implementing the lockdown did not bring expected benefits, because instead of reducing the number of deaths due to the COVID-19, individuals tend to die more from other causes.

Traditional Medicine

2021 ◽  
pp. 118-129
Author(s):  
Pavitra Solanki ◽  
Yasmin Sultana ◽  
Satyavir Singh
Keyword(s):  
At Risk ◽  
Antimicrobial Resistance ◽  
Traditional Medicine ◽  
Volatile Oil ◽  
World Health ◽  
Antibiotic Resistant ◽  
Life Saving ◽  
The World ◽  
History Of ◽  
Health Organization

Everybody is at risk of being infected by drug-resistant microscopic organisms. Managing with sickness has never been less demanding within the history of our species. At the current rate of antimicrobial resistance (AMR) in microbes, specialists foresee that battling infections tuberculosis, HIV, and intestinal sickness will become more complicated. Antimicrobial resistance is rendering numerous life-saving drugs useless. Antibiotic-resistant microbes, known as “superbugs,” are getting to be more various and more harmful, thanks to the proceeding abuse of anti-microbials. Natural medication offers an alternative to these progressively ineffectual drugs. According to the World Health Organization (WHO), traditional medicine is a holistic term enclosing diverse health practices. Concurring to a report by the College of Maryland Therapeutic Center, turmeric's volatile oil serves as a common anti-microbial.

scholarly journals The “Obiettivo Antibiotico” Campaign on Prudent Use of Antibiotics in Sicily, Italy: The Pilot Phase

2020 ◽  
Vol 17 (9) ◽  
pp. 3077 ◽  
Author(s):  
Martina Barchitta ◽  
Annalisa Quattrocchi ◽  
Andrea Maugeri ◽  
Maria Clara La Rosa ◽  
Claudia La Mastra ◽  
...  
Keyword(s):  
Social Media ◽  
Antimicrobial Resistance ◽  
General Public ◽  
Healthcare Professionals ◽  
Educational Interventions ◽  
World Health ◽  
Pilot Phase ◽  
The Public ◽  
The World ◽  
Health Organization

The issue of antimicrobial resistance (AMR) is a focus of the World Health Organization, which proposes educational interventions targeting the public and healthcare professionals. Here, we present the first attempt at a regionwide multicomponent campaign in Sicily (Italy), called “Obiettivo Antibiotico”, which aims to raise the awareness of prudent use of antibiotics in the public and in healthcare professionals. The campaign was designed by an interdisciplinary academic team, and an interactive website was populated with different materials, including key messages, letters, slogans, posters, factsheets, leaflets, and videos. The campaign was launched in November 2018 and, as of 21 December 2018, the website had a total of 1159 unique visitors, of which 190 became champions by pledging to take simple actions to support the fight against AMR. Data from social media showed that the audience was between 18 and 54 years of age, with a high proportion of female participants (64%). Interestingly, the LinkedIn page received more than 1200 followers, and Facebook 685 followers. The number of actions taken (pledges) by the audience was 458, evenly divided between experts (53%) and the general public (47%). Additional efforts are needed to reach more people, thus future efforts should focus on further promotion within the Sicilian region to sustain the engagement with the campaign.

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