Whole genome sequence of first Candida auris strain, isolated in Russia

2019 ◽  
Vol 58 (3) ◽  
pp. 414-416 ◽  
Author(s):  
Ivan M Pchelin ◽  
Daniil V Azarov ◽  
Maria A Churina ◽  
Igor A Ryabinin ◽  
Irina V Vibornova ◽  
...  
Keyword(s):  
South Asian ◽  
Genome Sequence ◽  
Draft Genome ◽  
Multidrug Resistant ◽  
Whole Genome Sequence ◽  
Candida Auris ◽  
Fluconazole Resistance ◽  
Russian Strain ◽  
Resistant Strains ◽  
Original Species

Abstract Candida auris is an emergent yeast pathogen, easily transmissible between patients and with high percent of multidrug resistant strains. Here we present a draft genome sequence of the first known Russian strain of C. auris, isolated from a case of candidemia. The strain clustered within South Asian C. auris clade and seemingly represented an independent event of dissemination from the original species range. Observed fluconazole resistance was probably due to F105L and K143R mutations in ERG11.

scholarly journals Epidemiology and Whole Genome Sequence Typing of Globally Emerging, Multidrug-Resistant Candida auris

2016 ◽  
Vol 3 (suppl_1) ◽  
Author(s):  
Kizee Etienne ◽  
Snigdha Vallabhaneni ◽  
Joveria Farooqi ◽  
Rana Jawad Asghar ◽  
Anuradha Chowdhary ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Multidrug Resistant ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Candida Auris

scholarly journals Draft Genome Sequence of a Highly ResistantStreptococcus pneumoniaeSerotype 15A Strain Isolated from Blood

2018 ◽  
Vol 6 (16) ◽  
pp. e00167-18 ◽  
Author(s):  
Revathy Arushothy ◽  
Norazah Ahmad ◽  
Fairuz Amran ◽  
Rohaidah Hashim ◽  
Nazirah Samsuddin ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Draft Genome ◽  
Multidrug Resistant ◽  
Sequence Type ◽  
Draft Genome Sequence ◽  
Antibiotic Resistant ◽  
Content Type ◽  
Resistance To Penicillin ◽  
Resistant Strains ◽  
Multidrug Resistant Strain

ABSTRACTAfter the introduction of the pneumococcal conjugate vaccine in Malaysia in recent years, the emergence of nonvaccine serotypes is of concern, particularly the antibiotic-resistant strains, with an increase specifically in serotype 15A. Here, we report the draft genome sequence ofStreptococcus pneumoniaestrain SS40_16, isolated from the blood sample of a 19-month-old female in 2016. SS40_16 is a multidrug-resistant strain with resistance to penicillin (MIC, ≥2 µg/ml), tetracycline, and trimethoprim-sulfamethoxazole. The strain belongs to serotype 15A and sequence type 1591 (ST1591).

scholarly journals Draft Genome Sequence of Invasive Salmonella enterica Serovar Cannstatt Harboring mcr-1.1, Isolated from a Fatal Sepsis Case

2021 ◽  
Vol 10 (8) ◽  
Author(s):  
Wantana Paveenkittiporn ◽  
Watcharaporn Kamjumphol ◽  
Anusak Kerdsin
Keyword(s):  
Genome Sequence ◽  
Salmonella Enterica ◽  
Draft Genome ◽  
Genomic Analysis ◽  
Multidrug Resistant ◽  
Sequence Type ◽  
Whole Genome Sequence ◽  
Content Type ◽  
Fatal Sepsis ◽  
M 14

ABSTRACT Here, we report the whole-genome sequence of multidrug-resistant Salmonella enterica serovar Cannstatt harboring mcr-1.1, isolated from a fatal sepsis case. Genomic analysis revealed that the isolate was sequence type 2390 carrying mcr-1.1, blaCTX-M-14, aac(3)IId, aac(6′)Iaa, floR, qnrS1, sul2, tetA, and tetM. Three Inc plasmids were observed, including the IncX4 plasmid containing mcr-1.1.

scholarly journals Draft Genome Sequence of Multidrug-Resistant Strain Citrobacter portucalensis MBTC-1222, Isolated from Uziza ( Piper guineense ) Leaves in Nigeria

2018 ◽  
Vol 6 (9) ◽  
Author(s):  
Etinosa O. Igbinosa ◽  
Jana Rathje ◽  
Diana Habermann ◽  
Erik Brinks ◽  
Gyu-Sung Cho ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Draft Genome ◽  
Noncoding Rnas ◽  
Multidrug Resistant ◽  
Whole Genome Sequence ◽  
Piper Guineense ◽  
Protein Coding ◽  
Antibiotic Resistant ◽  
Content Type ◽  
Multidrug Resistant Strain

ABSTRACT In this work, we report the draft whole-genome sequence of the multiply antibiotic-resistant Citrobacter portucalensis strain MBTC-1222 isolated from the uziza leafy vegetable in Nigeria. Sequence analysis showed the assembled genome size to be 4,881,935 bp, containing 4,603 protein-coding genes, 131 pseudogenes, 7 rRNAs, 74 tRNAs, and 9 noncoding RNAs (ncRNAs).

scholarly journals Whole-Genome Sequence of Acinetobacter baumannii Strain NUBRI-A, Isolated from a Hospitalized Patient in Khartoum, Sudan

2019 ◽  
Vol 8 (32) ◽  
Author(s):  
Sofia B. Mohamed ◽  
Mohamed Hassan ◽  
Abdalla Munir ◽  
Sumaya Kambal ◽  
Nusiba I. Abdalla ◽  
...  
Keyword(s):  
Acinetobacter Baumannii ◽  
Genome Sequence ◽  
Genomic Sequence ◽  
Draft Genome ◽  
Multidrug Resistant ◽  
Sequence Type ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Hospital Patient ◽  
Content Type

Acinetobacter baumannii has emerged as an important pathogen leading to multiple nosocomial outbreaks. Here, we describe the genomic sequence of a multidrug-resistant Acinetobacter baumannii sequence type 164 (ST164) isolate from a hospital patient in Sudan. To our knowledge, this is the first reported draft genome of an A. baumannii strain isolated from Sudan.

scholarly journals Whole-Genome Sequence Analysis of Multidrug-Resistant Enterobacter hormaechei Isolated from Imported Retail Shrimp

2020 ◽  
Vol 9 (50) ◽  
Author(s):  
Nagaraju Indugu ◽  
Laxmi Sharma ◽  
Charlene R. Jackson ◽  
Prashant Singh
Keyword(s):  
Genome Sequence ◽  
Draft Genome ◽  
Antibiotic Resistance Genes ◽  
Multidrug Resistant ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Genome Sequence Analysis ◽  
Content Type ◽  
Shrimp Sample ◽  
Enterobacter Hormaechei

ABSTRACT Here, we announce the draft genome sequence of Enterobacter hormaechei 2B-MC1, isolated from a shrimp sample collected from a farmer’s market in Atlanta, Georgia. The assembled genome sequence observed was 4,661,561 bp long with a G+C content of 55.3%. The isolate harbored sul1, sul2, qnrA1, oqxB, dfrA23, blaACT, floR, fosA, tet(A), aph(6)-Id, and aph(3″)-Ib antibiotic resistance genes.

scholarly journals Human Infections Caused by Clonally Related African Clade (Clade III) Strains of Candida auris in the Greater Houston Region

2020 ◽  
Vol 58 (7) ◽  
Author(s):  
S. Wesley Long ◽  
Matthew Ojeda Saavedra ◽  
Paul A. Christensen ◽  
James M. Musser ◽  
Randall J. Olsen
Keyword(s):  
United States ◽  
Genome Sequence ◽  
Clinical Laboratory ◽  
Draft Genome ◽  
The United States ◽  
Metropolitan Region ◽  
Whole Genome Sequence ◽  
Candida Auris ◽  
Content Type ◽  
African Clade

ABSTRACT Candida auris is a pathogen of considerable public health importance. It was first reported in 2009. Five clades, determined by genomic analysis and named by the distinct regions where they were initially identified, have been defined. We previously completed a draft genome sequence of an African clade (clade III) strain cultured from the urine of a patient hospitalized in the greater Houston metropolitan region (strain LOM). Although initially uncommon, reports of the African clade in the United States have grown to include a recent cluster in California. Here, we describe a second human C. auris infection in the Houston area. Whole-genome sequence analysis demonstrated the Houston patient isolates to be clonally related to one another but distantly related to other African clade organisms recovered in the United States or elsewhere. Infections in these patients were present on admission to the hospital and occurred several months apart. Taken together, the data demonstrate the emergence and persistence of a clonal C. auris population and highlights the importance of routine high-resolution genomic surveillance of emerging human pathogens in the clinical laboratory.

scholarly journals Draft Genome Sequence of the First Confirmed Isolate of Multidrug-Resistant Mycobacterium tuberculosis in Tasmania

2017 ◽  
Vol 5 (44) ◽  
Author(s):  
Sanjay S. Gautam ◽  
Micheál Mac Aogáin ◽  
Ronan F. O’Toole
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Genome Sequence ◽  
Draft Genome ◽  
Multidrug Resistant ◽  
Whole Genome Sequence ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Content Type ◽  
Global Challenge ◽  
Mdr Tb

ABSTRACT The spread of multidrug-resistant (MDR) tuberculosis (TB) has become a major global challenge. In 2016, Tasmania recorded its first known incidence of MDR-TB. Here, we report the draft whole-genome sequence of the Mycobacterium tuberculosis isolate from this case, TASMDR1, and describe single-nucleotide polymorphisms associated with its drug resistance.

scholarly journals Two Candida auris Cases in Germany with No Recent Contact to Foreign Healthcare—Epidemiological and Microbiological Investigations

2021 ◽  
Vol 7 (5) ◽  
pp. 380
Author(s):  
Joerg Steinmann ◽  
Thomas Schrauzer ◽  
Lisa Kirchhoff ◽  
Jacques F. Meis ◽  
Peter-Michael Rath
Keyword(s):  
South Asian ◽  
Multidrug Resistant ◽  
Health Care Facilities ◽  
Candida Auris ◽  
Contact Precautions ◽  
Asian Clade ◽  
Care Facilities ◽  
Long Time ◽  
European Health ◽  
Healthcare Associated

Candida auris has become a global fungal public health threat. This multidrug-resistant yeast is associated with nosocomial intra- and interhospital transmissions causing healthcare-associated infections. Here, we report on two C. auris cases from Germany. The two patients stayed in Germany for a long time before C. auris was detected during their hospitalization. The patients were isolated in single rooms with contact precautions. No nosocomial transmissions were detected within the hospital. Both C. auris isolates exhibited high minimum inhibitory concentrations (MICs) of fluconazole and one isolate additionally high MICs against the echinocandins. Microsatellite genotyping showed that both strains belong to the South Asian clade. These two cases are examples for appropriate in-hospital care and infection control without further nosocomial spread. Awareness for this emerging, multidrug-resistant pathogen is justified and systematic surveillance in European health care facilities should be performed.

scholarly journals Draft Genome Sequence of the Nitrogen-Fixing and Hormogonia-Inducing CyanobacteriumNostoc cycadaeStrain WK-1, Isolated from the Coralloid Roots ofCycas revoluta

2018 ◽  
Vol 6 (7) ◽  
Author(s):  
Yu Kanesaki ◽  
Masaki Hirose ◽  
Yuu Hirose ◽  
Takatomo Fujisawa ◽  
Yasukazu Nakamura ◽  
...  
Keyword(s):  
Host Plant ◽  
Genome Sequence ◽  
Draft Genome ◽  
Draft Genome Sequence ◽  
Whole Genome Sequence ◽  
Whole Genome ◽  
Nitrogen Fixing ◽  
Coralloid Roots ◽  
Cycas Revoluta

ABSTRACTWe report here the whole-genome sequence ofNostoc cycadaestrain WK-1, which was isolated from cyanobacterial colonies growing in the coralloid roots of the gymnospermCycas revoluta. It can provide valuable resources to study the mutualistic relationships and the syntrophic metabolisms between the cyanobacterial symbiont and the host plant,C. revoluta.

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