FP867VITAMIN D DEFICIENCY IS AN INDEPENDENT RISK FACTOR FOR URINARY TRACT INFECTIONS AFTER RENAL TRANSPLANTS

2015 ◽  
Vol 30 (suppl_3) ◽  
pp. iii367-iii367
Author(s):  
In Mee Han ◽  
Geun Woo Ryu ◽  
Jong Hyun Jhee ◽  
Hyung Woo Kim ◽  
Sul A Lee ◽  
...  
Keyword(s):  
Risk Factor ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Independent Risk Factor ◽  
Renal Transplants ◽  
Tract Infections

scholarly journals Vitamin D Deficiency Is an Independent Risk Factor for Urinary Tract Infections After Renal Transplants

Medicine ◽  
2015 ◽  
Vol 94 (9) ◽  
pp. e594 ◽  
Author(s):  
Young Eun Kwon ◽  
Hyunwook Kim ◽  
Hyung Jung Oh ◽  
Jung Tak Park ◽  
Seung Hyeok Han ◽  
...  
Keyword(s):  
Vitamin D ◽  
Risk Factor ◽  
Urinary Tract ◽  
Vitamin D Deficiency ◽  
Urinary Tract Infections ◽  
Independent Risk Factor ◽  
Renal Transplants ◽  
Tract Infections

scholarly journals Presepsin as a predictor of severe sepsis in urinary tract infection

2021 ◽  
Author(s):  
Yoshitaka Sekine ◽  
Kazuhiko Kotani ◽  
Daisuke Oka ◽  
Hiroshi Nakayama ◽  
Yoshiyuki Miyazawa ◽  
...  
Keyword(s):  
Septic Shock ◽  
Risk Factor ◽  
Severe Sepsis ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Roc Curve ◽  
Independent Risk Factor ◽  
Good Marker ◽  
Significant Difference ◽  
Tract Infections

Abstract Background Recently, presepsin is reported to be a biomarker for early diagnosis of sepsis and evaluation of prognosis in septic patients, but there are few reports about urinary-tract infections. The objective of this study is to evaluate whether presepsin is a recent marker for detecting severe sepsis, and whether it can predict the therapeutic course in UTI when compared with procalcitonin (PCT) and C-reactive protein (CRP), already used markers.Methods From April 2014 to December 2016, a total of 50 patients, who were admitted into Gunma university hospital with urinary-tract infections, were enrolled in this study. Vital signs, presepsin, PCT, CRP, white blood cell (WBC), causative diseases of urinary-tract infections and other data were evaluated at the enrollment, third and fifth days. The patients were divided into two groups; with (n=11) or without (n=39) septic shock at the enrollment day, and with (n=7) or without (n=43) sepsis at the fifth day, respectively. Presepsin was evaluated for systemic inflammatory response syndrome (SIRS) or septic shock. Results Concerning the enrollment day, there was no significant difference of presepsin between SIRS and non-SIRS groups (p=0.276). The median presepsin (pg/mL) was significantly higher in the septic shock group (p<0.001). Multivariate logistic regression analysis showed presepsin (≧ 500 pg/ml) was an independent risk factor associated with septic shock (p=0.007). ROC curve for diagnosing septic shock indicated an area under the curve (AUC) at 0.881 for presepsin (vs. 0.690, 0.583 and 0.527 for PCT, CRP and WBC, respectively). Concerning the 5th day after admission, the median presepsin of the enrollment day was significantly higher in SIRS groups than non-SIRS groups (p=0.006). On the other hand, PCT (≥ 2 ng/ml) of the enrollment day was an independent risk factor associated with SIRS. ROC curve for diagnosing sepsis at the fifth day indicated an AUC at 0.837 for PCT (vs. 0.817, 0.811 and 0.802 for presepsin, CRP and WBC, respectively).Conclusions This study shows that presepsin may be a good marker for diagnosis of severe patients who need vasopressor therapy at the data of admission, and PCT may be a good marker for predicting hard-to-treat cases in UTI.

scholarly journals Presepsin as a predictor of septic shock in patients with urinary tract infection

BMC Urology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yoshitaka Sekine ◽  
Kazuhiko Kotani ◽  
Daisuke Oka ◽  
Hiroshi Nakayama ◽  
Yoshiyuki Miyazawa ◽  
...  
Keyword(s):  
Septic Shock ◽  
Risk Factor ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Roc Curve ◽  
Independent Risk Factor ◽  
Multivariate Logistic Regression Analysis ◽  
University Hospital ◽  
Significant Difference ◽  
Tract Infections

Abstract Background Recently, presepsin has been reported to be a useful biomarker for early diagnosis of sepsis and evaluation of prognosis in septic patients. However, few reports have evaluated its usefulness in patients with urinary tract infections (UTI). This study aimed to evaluate whether presepsin could be a valuable marker for detecting severe sepsis, and whether it could predict the therapeutic course in patients with UTI compared with markers already used: procalcitonin (PCT) and C-reactive protein (CRP). Methods From April 2014 to December 2016, a total of 50 patients with urinary tract infections admitted to Gunma university hospital were enrolled in this study. Vital signs, presepsin, PCT, CRP, white blood cell (WBC) count, causative agents of urinary-tract infections, and other data were evaluated on the enrollment, third, and fifth days. The patients were divided into two groups: with (n = 11) or without (n = 39) septic shock on the enrollment day, and with (n = 7) or without (n = 43) sepsis on the fifth day, respectively. Presepsin was evaluated as a biomarker for systemic inflammatory response syndrome (SIRS) or septic shock. Results Regarding the enrollment day, there was no significant difference of presepsin between the SIRS and non-SIRS groups (p = 0.276). The median value of presepsin (pg/mL) was significantly higher in the septic shock group (p < 0.001). Multivariate logistic regression analysis showed that presepsin (≥ 500 pg/ml) was an independent risk factor for septic shock (p = 0.007). ROC curve for diagnosing septic shock indicated an area under the curve (AUC) of 0.881 for presepsin (vs. 0.690, 0.583, and 0.527 for PCT, CRP and WBC, respectively). Regarding the 5th day after admission, the median presepsin value on the enrollment day was significantly higher in the SIRS groups than in the non-SIRS groups (p = 0.006). On the other hand, PCT (≥ 2 ng/ml) on the enrollment day was an independent risk factor for SIRS. ROC curve for diagnosing sepsis on the fifth day indicated an AUC of 0.837 for PCT (vs. 0.817, 0.811, and 0.802 for presepsin, CRP, and WBC, respectively). Conclusions This study showed that presepsin may be a good marker for diagnosing septic shock based on admission data in patients with UTI.

Intestinal microbiome as a risk factor for urinary tract infections in children

2018 ◽  
Vol 37 (10) ◽  
pp. 1881-1891 ◽  
Author(s):  
Niko Paalanne ◽  
Aleksi Husso ◽  
Jarmo Salo ◽  
Oskari Pieviläinen ◽  
Mysore V. Tejesvi ◽  
...  
Keyword(s):  
Risk Factor ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Intestinal Microbiome ◽  
Tract Infections

High incidence of urinary tract infections after photoselective laser vaporisation of the prostate: a risk factor analysis of 665 patients

2019 ◽  
Vol 38 (7) ◽  
pp. 1787-1794
Author(s):  
Kathrin Bausch ◽  
Jürg Motzer ◽  
Jan A. Roth ◽  
Marc Dangel ◽  
Hans-Helge Seifert ◽  
...  
Keyword(s):  
Factor Analysis ◽  
Risk Factor ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Risk Factor Analysis ◽  
High Incidence ◽  
Tract Infections ◽  
Laser Vaporisation

scholarly journals Antibiotic resistance in isolates recovered from women with community-acquired urinary tract infections presenting to a tertiary care emergency department

CJEM ◽  
2012 ◽  
Vol 14 (05) ◽  
pp. 295-305 ◽  
Author(s):  
Lyne Filiatrault ◽  
Rachel M. McKay ◽  
David M. Patrick ◽  
Diane L. Roscoe ◽  
Grahame Quan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Emergency Department ◽  
Antibiotic Resistance ◽  
Risk Factor ◽  
Urinary Tract ◽  
Urinary Tract Infections ◽  
Tertiary Care ◽  
Antibiotic Use ◽  
Adult Females ◽  
Tract Infections

ABSTRACTIntroduction:We sought to determine the antibiotic susceptibility of organisms causing community-acquired urinary tract infections (UTIs) in adult females attending an urban emergency department (ED) and to identify risk factors for antibiotic resistance.Methods:We reviewed the ED charts of all nonpregnant, nonlactating adult females with positive urine cultures for 2008 and recorded demographics, diagnosis, complicating factors, organism susceptibility, and risk factors for antibiotic resistance. Odds ratios (ORs) and 95% confidence intervals (CIs) for potential risk factors were calculated.Results:Our final sample comprised 327 UTIs: 218 were cystitis, of which 22 were complicated cases and 109 were pyelonephritis, including 22 complicated cases.Escherichia coliaccounted for 82.3% of all UTIs, whereasStaphylococcus saprophyticusaccounted for 5.2%. In uncomplicated cystitis, 9.5% of all isolates were resistant to ciprofloxacin and 24.0% to trimethoprim-sulfamethoxazole (TMP-SMX). In uncomplicated pyelonephritis, 19.5% of isolates were resistant to ciprofloxacin and 36.8% to TMP-SMX. In UTI (all types combined), any antibiotic use within the previous 3 months was a significant risk factor for resistance to both ciprofloxacin (OR 3.34, 95% CI 1.16–9.62) and TMP-SMX (OR 4.02, 95% CI 1.48–10.92). Being 65 years of age or older and having had a history of UTI in the previous year were risk factors only for ciprofloxacin resistance.Conclusions:E. coliwas the predominant urinary pathogen in this series. Resistance to ciprofloxacin and TMP-SMX was high, highlighting the importance of relevant, local antibiograms. Any recent antibiotic use was a risk factor for both ciprofloxacin and TMP-SMX resistance in UTI. Our findings should be confirmed with a larger prospective study.

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