scholarly journals Characterization of Volatile Organic Compound Metabolites in Cigarette Smokers, Electronic Nicotine Device Users, Dual Users, and Nonusers of Tobacco

2019 ◽  
Vol 22 (2) ◽  
pp. 264-272 ◽  
Author(s):  
Rachel J Keith ◽  
Jessica L Fetterman ◽  
Olusola A Orimoloye ◽  
Zeina Dardari ◽  
Pawel K Lorkiewicz ◽  
...  
Keyword(s):  
Cardiovascular Effects ◽  
Cross Sectional Study ◽  
Tobacco Product ◽  
Linear Regression Models ◽  
Cross Sectional ◽  
Potential Health ◽  
Cigarette Smokers ◽  
Use Patterns ◽  
Product Use ◽  
Volatile Organic

Abstract Introduction Limited research exists about the possible cardiovascular effects of electronic nicotine delivery systems (ENDS). We therefore sought to compare exposure to known or potentially cardiotoxic volatile organic compounds (VOCs) in ENDS users, smokers, and dual users. Methods A total of 371 individuals from the Cardiovascular Injury due to Tobacco Use study, a cross-sectional study of healthy participants aged 21–45 years, were categorized as nonusers of tobacco (n = 87), sole ENDS users (n = 17), cigarette smokers (n = 237), and dual users (n = 30) based on 30-day self-reported tobacco product use patterns. Participants provided urine samples for VOC and nicotine metabolite measurement. We assessed associations between tobacco product use and VOC metabolite measures using multivariable-adjusted linear regression models. Results Mean (SD) age of the population was 32 (±6.8) years, 55% men. Mean urinary cotinine level in nonusers of tobacco was 2.6 ng/mg creatinine, whereas cotinine levels were similar across all tobacco product use categories (851.6–910.9 ng/mg creatinine). In multivariable-adjusted models, sole ENDS users had higher levels of metabolites of acrolein, acrylamide, acrylonitrile, and xylene compared with nonusers of tobacco, but lower levels of most VOC metabolites compared with cigarette smokers or dual users. In direct comparison of cigarettes smokers and dual users, we found lower levels of metabolites of styrene and xylene in dual users. Conclusion Although sole ENDS use may be associated with lower VOC exposure compared to cigarette smoking, further study is required to determine the potential health effects of the higher levels of certain reactive aldehydes, including acrolein, in ENDS users compared with nonusers of tobacco. Implications ENDS use in conjunction with other tobacco products may not significantly reduce exposure to VOC, but sole use does generally reduce some VOC exposure and warrants more in-depth studies.

scholarly journals Protocol for a Japanese nationwide repeated cross-sectional study to assess tobacco and nicotine product use behaviour after market introduction of tobacco heating products (THPs)

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 739 ◽  
Author(s):  
Jason Adamson ◽  
Claudia Kanitscheider ◽  
Krishna Prasad ◽  
Oscar M. Camacho ◽  
Elisabeth Beyerlein ◽  
...  
Keyword(s):  
Risk Perceptions ◽  
Population Level ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Potential Health ◽  
Product Use ◽  
Consumer Demographics ◽  
One Year ◽  
Behavioural Aspects

Background - In recent years there has been a proliferation of alternative tobacco and nicotine products that reduce consumers’ exposure to harmful substances and therefore have the potential to reduce risk to health. Post-market surveillance enables the evaluation of newly introduced tobacco and nicotine products (aka potentially reduced risk products (PRRPs)) at a population level. This study aims to investigate tobacco and nicotine consumer demographics and discover how people are using these products, and characterise behavioral trends as transitions between tobacco heated products (THPs) and other nicotine products. These behavioural aspects, in conjunction with the intrinsic risk of the product, are essential for assessing the potential health effects and establishing a population risk assessment. Design and methods - This epidemiological cross-sectional study will collect data using a self-administered study instrument from the general Japanese population aged 20 years and older. The targeted sampling size is up to 5,000 participants per study wave. The study addresses the following objectives: estimation of tobacco and nicotine use prevalence; characterisation of  product usage by product type; changes in use behaviour in general, with particular emphasis on the introduction of THPs in the time period of one year; risk perceptions of different tobacco products and no tobacco usage; and participant perceived health status and quality of life. Discussion - The description of tobacco and nicotine product use behaviour, the estimation of prevalence data, the measuring of product-specific risk perception and the change of tobacco use behaviour within one year will allow for a comprehensive assessment of the effect of introducing THPs into a market. These data could also be used to inform a system dynamics population model in order to estimate the public health impact of introducing a THP into the Japanese market.

scholarly journals Are Heated Tobacco Product Users Less Likely to Quit than Cigarette Smokers? Findings from THINK (Tobacco and Health IN Korea) Study

2020 ◽  
Vol 17 (22) ◽  
pp. 8622
Author(s):  
Cheol Min Lee ◽  
Choon-Young Kim ◽  
Kiheon Lee ◽  
Sungroul Kim
Keyword(s):  
South Korea ◽  
Cross Sectional Study ◽  
Tobacco Product ◽  
Cross Sectional ◽  
Cigarette Smokers ◽  
Tobacco Products ◽  
Tobacco Sales ◽  
Quit Attempts ◽  
Stop Smoking Services ◽  
The Difference

Since the advent of heated tobacco products in June 2017 in South Korea, the sale of heated tobacco products accounted for 10.5% of total tobacco sales in 2019. However, the decreasing trend in total tobacco sales is gradually weakening and the number of visitors using stop smoking services has also dropped. This study examines the association between the use of new tobacco products and related products and cessation behaviors. A cross-sectional study using a self-administered questionnaire was conducted from March 2019 to July 2019 for 2831 adult tobacco users. The difference in rates of quit attempts using the type of tobacco products and related products in the past year were noted (55.6% (any cigarette smoker), 46.7% (any e-cigarette user), and 39.6% (any heated tobacco product user)). About a 30% increase in quit attempts was observed for the triple users of either conventional cigarette or heated tobacco product than exclusive users. Exclusive heated tobacco product and e-cigarette users were approximately 40% and 20% less likely to quit the product they used than exclusive cigarette smokers, respectively. These findings can explain recent occurrences in South Korea, such as the reduction of visitors at smoking cessation clinics and the attenuation of the decline in tobacco sales.

scholarly journals Combustible cigarettes, heated tobacco products, combined product use, and periodontal disease: A cross-sectional JASTIS study

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0248989
Author(s):  
Takashi Yoshioka ◽  
Takahiro Tabuchi
Keyword(s):  
Periodontal Disease ◽  
Primary Outcome ◽  
Periodontal Diseases ◽  
Cross Sectional Study ◽  
Tobacco Product ◽  
Internet Survey ◽  
Cross Sectional ◽  
Product Use ◽  
Using Data ◽  
Prevalence Ratios

Background Combustible cigarettes have detrimental effects on periodontal disease. However, little evidence is available regarding new heated tobacco product (HTP) use and combined product use (both combustible cigarettes and HTPs). This study aimed to examine the association of combustible cigarettes, HTPs, and combined product use with periodontal disease simultaneously. Materials and methods This cross-sectional study was conducted using data from the 2019 arm of the longitudinal Japan “Society and New Tobacco” Internet Survey. Combustible cigarette users, HTP users, combined product users, never-users, and former users’ data were separately obtained. In the present study, the primary outcome was self-reported periodontal disease. We estimated adjusted prevalence ratios (PRs) and confidence intervals (CIs) using multivariable modified Poisson regression analysis after adjusting for 12 confounders. Results Of the 10,439 JASTIS respondents, the numbers of users of combustible cigarettes only, HTPs only, and both products were 1,304, 437, and 1,049, respectively. Compared with never-users, HTP use was significantly associated with the prevalence of self-reported periodontal diseases (PR 1.43, 95% CI 1.03–1.62). Moreover, former users, combustible cigarette users, and combined product users also showed significant associations (PR 1.56, 95% CI 1.35–1.80; PR 1.29, 95% CI 1.03–1.62; and PR 1.55, 95% CI 1.20–1.99, respectively). Conclusions Users of HTPs, combustible cigarettes, and combined products as well as former users were all significantly associated with a higher prevalence of periodontal diseases compared to never-users.

scholarly journals Use of electronic cigarettes and heated tobacco products during the Covid-19 pandemic

2022 ◽  
Vol 12 (1) ◽  
Author(s):  
Silvano Gallus ◽  
Chiara Stival ◽  
Giulia Carreras ◽  
Giuseppe Gorini ◽  
Andrea Amerio ◽  
...  
Keyword(s):  
Odds Ratio ◽  
Electronic Cigarettes ◽  
Cross Sectional Study ◽  
Tobacco Product ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cigarette Smokers ◽  
Web Based ◽  
Never Smokers ◽  
Hardcore Smokers

AbstractOnly a few studies investigated changes in electronic cigarette (e-cigarette) and heated tobacco product (HTP) use during pandemic restrictions. We conducted a web-based cross-sectional study of a representative sample of 6,003 Italian adults during the strictest phase of the Covid-19 lockdown (April–May 2020). Participants were asked to report changes in e-cigarette and HTP use compared to before the pandemic. E-cigarette users increased from 8.1% to 9.1% and HTP users from 4.0% to 4.5%. Among e-cigarette non-users before lockdown, 1.8% started using e-cigarettes during lockdown. New users were more frequently younger (p for trend 0.001), men (odds ratio, OR 1.56; 95% confidence interval, CI: 1.03–2.34), cannabis users (OR 2.35; 95% CI: 1.33–4.13), gamblers (OR 3.34; 95% CI: 2.18–5.11) and individuals with anxiety symptoms (OR 1.58; 95% CI: 1.00–2.52). 1.0% of HTP non-users started using it during lockdown. New users were less frequently current than never cigarette smokers (OR 0.19; 95% CI: 0.06–0.61) and more frequently gamblers (OR 2.23; 95% CI: 1.22–4.07). E-cigarettes and HTPs played little role as smoking cessation tools for hardcore smokers but rather provided opportunities for young never smokers to engage in socially acceptable activities, perhaps reflecting the obstacles they faced in obtaining other addictive substances during confinement.

scholarly journals Mortality Risks Associated With Dual– and Poly–Tobacco-Product Use in the United States

2019 ◽  
Author(s):  
Kelvin Choi ◽  
Maki Inoue-Choi ◽  
Timothy S McNeel ◽  
Neal D Freedman
Keyword(s):  
United States ◽  
The United States ◽  
Tobacco Product ◽  
Cigarette Smokers ◽  
Tobacco Products ◽  
Mortality Risks ◽  
Use Patterns ◽  
Product Use ◽  
Nationally Representative ◽  
The Impact

Abstract Increasing numbers of adults in the United States use more than 1 tobacco product. Most use cigarettes in combination with other tobacco products. However, little is known about the all-cause and cancer-specific mortality risks of dual– and poly–tobacco-product use. We examined these associations by pooling nationally representative data from the 1991, 1992, 1998, 2000, 2005, and 2010 National Health Interview Surveys (n = 118,144). Mortality information was obtained through linkage to the National Death Index. Cigarette smokers who additionally used other tobacco products smoked as many if not more cigarettes per day than exclusive cigarette smokers. Furthermore, cigarette smokers who additionally used other tobacco products had mortality risks that were as high as and sometimes higher than those of exclusive cigarette smokers. As tobacco use patterns continue to change and diversify, investigators in future studies need to carefully assess the impact of noncigarette tobacco products on cigarette use and determine associated disease risks.

scholarly journals Protocol for a Japanese nationwide repeated cross-sectional study to assess tobacco and nicotine product use behaviour after market introduction of Tobacco Heating Products (THPs) (Preprint)

2019 ◽  
Author(s):  
◽  
Claudia Kanitscheider ◽  
Krishna Prasad ◽  
Oscar M Camacho ◽  
Elisabeth Beyerlein ◽  
...  
Keyword(s):  
Risk Perceptions ◽  
Population Level ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Potential Health ◽  
Product Use ◽  
Consumer Demographics ◽  
One Year ◽  
Behavioural Aspects

UNSTRUCTURED Background - In recent years there has been a proliferation of alternative tobacco and nicotine products that reduce consumers’ exposure to harmful substances and therefore have the potential to reduce risk to health. Post-market surveillance enables the evaluation of newly introduced tobacco and nicotine products (aka Potentially Reduced Risk Products (PRRPs)) at a population level. This study aims to investigate tobacco and nicotine consumer demographics and discover how people are using these products, and characterise behavioral trends as transitions between tobacco heated products (THPs) and other nicotine products. These behavioural aspects, in conjunction with the intrinsic risk of the product, are essential for assessing the potential health effects and establishing a population risk assessment. Design and Methods - This epidemiological cross-sectional study will collect data using a self-administered study instrument from the general Japanese population aged 20 years and older. The targeted sampling size is up to 5,000 participants per study wave. The study addresses the following objectives: estimation of tobacco and nicotine use prevalence; characterisation of product usage by product type; changes in use behaviour in general, with particular emphasis on the introduction of THPs in the time period of one year; risk perceptions of different tobacco products and no tobacco usage; and participant perceived health status and Quality of Life. Discussion - The description of tobacco and nicotine product use behaviour, the estimation of prevalence data, the measuring of product-specific risk perception and the change of tobacco use behaviour within one year will allow for a comprehensive assessment of the effect of introducing THPs into a market. These data could also be used to inform a System Dynamics Population Model in order to estimate the public health impact of introducing a THP into the Japanese market.

scholarly journals Cross-sectional Survey to Assess Tobacco and Nicotine Product Use since the Introduction of Tobacco Heating Products in Japan: Wave 1

2021 ◽  
Vol 7 (3) ◽  
pp. 210-220
Author(s):  
Joshua D. Jones ◽  
Jason Adamson ◽  
Claudia Kanitscheider ◽  
Krishna Prasad ◽  
Oscar M. Camacho ◽  
...  
Keyword(s):  
Population Level ◽  
Tobacco Product ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Use Patterns ◽  
Product Use ◽  
Key Population ◽  
Level Data ◽  
Japanese Residents ◽  
And Behavior

Objective: In this study, we obtained key population-level data on use patterns and behavior relating to tobacco and nicotine products in Japan. Methods: We performed a nationwide cross-sectional survey of the general population in Japan in 2019 to assess use patterns after the introduction of tobacco heating products (THPs). Eligible participants were Japanese residents, aged 20 years or older who consented to complete the survey. Individuals living in institutions were excluded. A 3-stage probability sampling method was applied that was geographically stratified by street blocks proportionate to population density. Respondents self-reported patterns of product use and reasons for THP use. Results: Complete responses were available from 5306 individuals, of whom 933.5 (17.6%) were current users, 984.2 (18.5%) were former users, and 3388.4 (63.9%) were never users of tobacco products (weighted respondent totals). Cigarettes were used by 14.6% of current tobacco product users and THPs by 5.3%. Cigarettes and THPs were used exclusively by 64.5% and 12.2%, respectively, and both were used by 12.7%. The most common reasons reported for THP use were perceived reduction in harm to self and others compared to cigarettes. Conclusions: Whereas the prevalence of cigarette use in Japan is decreasing, THPs seem to be increasingly used as long-term alternatives to cigarette smoking.

scholarly journals Smoking and Vaping Among a National Sample of U.S. Adults During the COVID-19 Pandemic

2021 ◽  
Author(s):  
Sara Kalkhoran ◽  
Douglas E Levy ◽  
Nancy A Rigotti
Keyword(s):  
Cigarette Smoking ◽  
Perceived Risk ◽  
Severe Disease ◽  
National Sample ◽  
Cigarette Use ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Cigarette Smokers ◽  
Use Patterns ◽  
Product Use

Introduction: With concerns about cigarette smoking as a risk factor for severe disease from COVID-19, understanding nicotine and tobacco use patterns is important for preventive efforts. We aimed to understand changes in product use behaviors among U.S. adult combustible cigarette smokers and electronic cigarette (e-cigarette) users. Methods: In August 2020, we conducted a cross-sectional survey of a nationally-representative sample of adults age >18 in the NORC AmeriSpeak Panel who reported past 6-month use of combustible cigarettes or e-cigarettes. Multivariable logistic regression assessed factors associated with increased product use and quit attempts since hearing about COVID-19. Results: 1024 past 6-month cigarette smokers and/or e-cigarette users were surveyed. Among cigarette smokers, 45% reported no change in cigarette smoking and 33% increased cigarette smoking since hearing about COVID-19. Higher stress was associated with increased cigarette smoking. Among e-cigarette users, 41% reported no change in and 23% reported increasing e-cigarette use. 26% of cigarette smokers and 41% of e-cigarette users tried to quit because of COVID-19. Higher perceived risk of COVID-19 was associated with attempts to quit combustible cigarettes (AOR 2.37, 95% CI 1.59-3.55) and e-cigarettes (AOR 3.14, 1.73-5.70). Conclusions: Cigarette and e-cigarette use patterns varied in response to the COVID-19 pandemic. Most cigarette smokers and e-cigarette users perceived product use as increasing COVID-19-related health risks, and this was associated with attempts to quit. Others, especially those reporting higher stress, increased product use. Proactive provision of cessation support to smokers and e-cigarette users may help mitigate stress-related increases in product use during the COVID-19 pandemic.

scholarly journals Perceptions of Harmfulness of Heated Tobacco Products Compared to Combustible Cigarettes among Adult Smokers in Japan: Findings from the 2018 ITC Japan Survey

2020 ◽  
Vol 17 (7) ◽  
pp. 2394 ◽  
Author(s):  
Shannon Gravely ◽  
Geoffrey T. Fong ◽  
Edward Sutanto ◽  
Ruth Loewen ◽  
Janine Ouimet ◽  
...  
Keyword(s):  
Social Media ◽  
Tobacco Industry ◽  
Cross Sectional Study ◽  
Tobacco Product ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cigarette Smokers ◽  
Tobacco Products ◽  
Reduced Risk ◽  
Marketing Messages

In Japan, the tobacco industry promotes heated tobacco products (HTPs) as a reduced-risk tobacco product. This study examines: (1) smokers’ harm perceptions of HTPs relative to combustible cigarettes; (2) differences in relative harm perceptions between exclusive smokers and smokers who use HTPs (concurrent users) and between concurrent users based on frequency of product use; and (3) if smokers who were exposed to HTP advertising hold beliefs that are consistent with marketing messages of lower harmfulness. This cross-sectional study included 2614 adult exclusive cigarette smokers and 986 concurrent users who reported their perceptions of harmfulness of HTPs compared to cigarettes, as well as their exposure to HTP advertising in the last six months. Among all smokers, 47.5% perceive that HTPs are less harmful than cigarettes, 24.6% perceive HTPs to be equally as harmful, 1.8% perceive HTPs as more harmful, and 26.1% did not know. Concurrent users are more likely than exclusive smokers to believe that HTPs are less harmful (62.1% versus 43.8%, p < 0.0001) and less likely to report that they did not know (14.3% versus 29.4%, p < 0.0001). Frequent HTP users are more likely than infrequent users to believe that HTPs are less harmful (71.7% versus 57.1%, p ≤ 0.001). Believing that HTPs are less harmful than cigarettes was associated with noticing HTP advertising on TV (p = 0.0005), in newspapers/magazines (p = 0.0001), on posters/billboards (p < 0.0001), in stores where tobacco (p < 0.0001) or where HTPs (p < 0.0001) are sold, on social media (p < 0.0001), or in bars/pubs (p = 0.04). HTP users were significantly more likely than non-HTP users to believe that HTPs are less harmful than cigarettes, with this belief being more prominent among frequent users. Smokers who have been exposed to HTP advertising were more likely to perceive HTPs as less harmful than cigarettes.

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