A Prospective and Retrospective View of Pediatric Hematology/Oncology

2006 ◽  
Author(s):  
Momcilo Jankovic ◽  
Giuseppe Masera
Keyword(s):  
Health Care Professionals ◽  
Pediatric Hematology ◽  
The Past ◽  
Life Threatening Illness ◽  
Retrospective View ◽  
Simple Question ◽  
Life Threatening ◽  
Working Together ◽  
History Of ◽  
The Moment

How does one help a family whose child has been diagnosed with a life-threatening illness? It is a deceptively simple question with complicated answers. This brief chapter is not meant to be a history of biopsychosocial pediatric oncology, and it does not cover every theme. The explosion of studies on children with cancer over these past decades (Pizzo & Poplack, 2001) renders a retrospective look formidable and subjective. The sole purpose of this retrospective examination into the earliest beginnings is to place into context some of the main themes that have appeared over the past years, so that they can serve as a foundation for our recommendations for future intervention and research in the field. That is our assigned task. Much of the review reflects personal respective experiences beginning in the late 1960s. The chapters that form this volume, written by many of the most experienced psychosocial researchers who have brought the field so far forward over these many years, are the state of the art, tell us where we have been most recently, and tell us in greater detail where we are at the moment. Where does our psychosocial history begin? What have we done these past many years to help the children and their families cope with the illness and its treatment? With due awareness of the subjectivity and inevitable unfairness of our venture, we undertake the task with due apologies for any omissions that may occur in this retrospective review. As we begin to look in some detail at the main themes formed over the past four decades, we place our review into the context of four preambles: a multidisciplinary and international effort; an alliance between physicians and parents; research and service; and a sharing of the research wealth with economically struggling countries. From the earliest years, the effort to care for the child with cancer has been multidisciplinary, multi-institutional, and international, involving a highly cooperative and collaborative effort of physicians, nurses, psychologists, social workers, and allied health care professionals working together across national borders.

A short history of Polish formations protecting the governing bodies of the state

2021 ◽  
Vol 1 (38) ◽  
pp. 75-84
Author(s):  
Aneta Drożdż
Keyword(s):  
Twentieth Century ◽  
The State ◽  
Short History ◽  
Control Subsystem ◽  
State Security ◽  
The Past ◽  
Rules And Principles ◽  
History Of ◽  
Important People ◽  
The Moment

This paper presents a short history of Polish formations protecting the governing bodies of the state, starting from the moment Poland regained independence at the end of the twentieth century. The considerations are presented against the rules and principles of the functioning of the state security system, with particular emphasis on the control subsystem. This paper demonstrates the need to research attitudes to safety in the past, in order to develop and apply effective contemporary solutions. The considerations contained in it also concern the existing threats to the management of state organs. They may contribute to further discussions on the purpose and rules of operation of the formation which is supposed to protect the most important people in the state.

Possible GoLytely-Associated Cardiac Arrest: A Case Report and Literature Review

2019 ◽  
Vol 33 (3) ◽  
pp. 364-367 ◽  
Author(s):  
Yoonsun Mo ◽  
Shiv Gandhi ◽  
Jose Orsini
Keyword(s):  
Cardiac Arrest ◽  
Abdominal Pain ◽  
Sudden Cardiac Arrest ◽  
Lower Abdominal Pain ◽  
The Past ◽  
Life Threatening ◽  
History Of ◽  
Artery Disease ◽  
Possible Cause

Purpose: To report a case of sudden cardiac arrest possibly associated with the administration of GoLytely® (polyethylene glycol 3350 and electrolytes). Summary: A 60-year-old male with a history of hypertension, hyperlipidemia, type 2 diabetes, and coronary artery disease presented to the emergency department with complaints of constipation and lower abdominal pain over the past week, and the inability to urinate over the past day. The patient had received GoLytely as treatment to alleviate symptoms of constipation and abdominal pain. However, several hours after administration of the bowel prep solution, the patient suffered an episode of cardiac arrest. After ruling out other possible etiologies, GoLytely was suspected as a possible cause of cardiac arrest. The patient had suffered an anoxic brain injury and remained intubated and unconscious until he eventually expired, 20 days after the event. Conclusion: Although GoLytely appears to be a safe agent with fewer side effects, clinicians need to be mindful of potential life-threatening adverse events following GoLytely administration and monitor patients closely during and after administration.

scholarly journals From Sketches to Publication: The Genesis of the Essai D'une Carte Géologique by Omalius D'halloy and Coquebert de Montbret (1810-1823)

2007 ◽  
Vol 26 (1) ◽  
pp. 31-53
Author(s):  
Isabelle Laboulais
Keyword(s):  
History Of Cartography ◽  
Critical Step ◽  
The Past ◽  
Map Construction ◽  
Geological Maps ◽  
History Of ◽  
Geological Map ◽  
The Moment

While the Essai d'une carte géologique published in 1822 did not achieve the fame that its authors had hoped for, its history nevertheless deserves a closer look. Although its scale (about 1:3,700,000), and the technique used for making it (the map was coloured by hand at a time when the first geological maps printed in colour were appearing) make it a map of the past, it nevertheless testifies to the experiments and even cartographic tinkerings that were conceived in the 1810s by conciliating the expectations of the administration and those of science. Moreover, it offers a good example of the conditions of map production at that time. Without suggesting that the appearance of that Essai constituted a critical step in the history of cartography, this article examines the different steps that led to its publication, by considering first the investigative methods, then the different stages of map construction, and finally the uncertainties surrounding its publication, in order to grasp the stakes of such an enterprise, at the moment when reflections on the making of a geological map of France were developing, in particular at the École des mines.

scholarly journals Table Manners

2020 ◽  
Vol 5 ◽  
pp. 20-29
Author(s):  
Christopher Wesolowski
Keyword(s):  
Western Europe ◽  
Upper Echelons ◽  
Late Medieval ◽  
The Past ◽  
Social Customs ◽  
Simple Question ◽  
History Of ◽  
The Way

Why do we eat the way we do? It is a simple question, but one that is rooted in a deep history of social customs and politics. This paper surveys the past thousand years of table manners through looking at popular courtesy handbooks both translated and written in late medieval Western Europe. It has been argued that table manners are imposed by the royalty and the upper echelons of society in order to have control over the functions of the middle and lower classes, but this paper extends this idea to explore how the population sought to either make fun of or emulate their higher ups. By looking at the history of table manners a great deal can be explored regarding the way in which medieval peoples thought about how they ate, and why it mattered.

The British Committee and International Society: History and Theory

2014 ◽  
Author(s):  
Brunello Vigezzi
Keyword(s):  
Critical Point ◽  
International Society ◽  
Future Development ◽  
Power Relations ◽  
English School ◽  
The Past ◽  
History Of ◽  
The Moment ◽  
British Committee ◽  
Point Of Departure

The British Committee on the Theory of International Politics is generally considered the original core of the “English School.” Equally often, scholars have identified as one of its characteristic elements the importance it attributed to “international society” as a force aimed at enlivening and regulating, as far as possible, power relations between states. The attention it paid to international society is also seen as consistent with the importance the authors of the British Committee attributed to “history” and in particular to the “history of international society” as a means to understand and reconstruct international life in the past and the present. However, the internal history of the British Committee is all too often neglected. Studies concerned with the orientations of the English School have mainly sought to analyze the thinking of this or that author without considering the work of the British Committee as a whole. In other words, scholars have tended to pay little attention to the moment when the British Committee began to examine “international society” and the manner in which it did so. In particular, the achievement of the British Committee discussions during 1961–1962 was important, and it was the beginning of a development of great interest. The various texts, the debates, do not limit themselves to a sort of rich and varied list of the component parts of an “international society.” Instead, they paint an overall picture, and they guarantee an interconnection between the reflections of the individuals and the overall orientation of the Committee. Moreover, they are the critical point of departure for the future development of theory.

scholarly journals A brief history of therapy for traumatic spinal cord injury

2004 ◽  
Vol 16 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Jason Lifshutz ◽  
Austin Colohan
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Social Impact ◽  
Traumatic Spinal Cord Injury ◽  
The Past ◽  
Clinical Innovation ◽  
Retrospective View ◽  
Cord Injury ◽  
History Of ◽  
The Individual

There are few more devastating injuries that afflict man than those associated with spinal cord injury (SCI). The economic, psychological, and social impact are encompassing and enormous to the individual and society. During the last several years, there has been a renewed interest in the study of SCI, with the hope of finding a cure. It is appropriate, then, to examine the efforts accomplished throughout medical history. With this retrospective view, potential avenues for future treatment become more apparent and clear. As in the past, the integration of basic science and clinical innovation will create the path toward progress for treatment of this disease.

scholarly journals QOLP-05. PREDICTING SURVIVAL WITH THE HEIDELBERG PROGNOSTIC MODEL AFTER SALVAGE STEREOTACTIC RADIOSURGERY OF PREVIOUSLY IRRADIATED PROGRESSIVE HIGH-GRADE GLIOMAS

2019 ◽  
Vol 21 (Supplement_6) ◽  
pp. vi198-vi198
Author(s):  
Federico Ampil ◽  
Troy Richards ◽  
Nestor dela Cruz
Keyword(s):  
Stereotactic Radiosurgery ◽  
Prognostic Model ◽  
Survival Rates ◽  
Prognostic Scores ◽  
High Grade ◽  
Life Threatening Illness ◽  
Life Threatening ◽  
History Of ◽  
High Grade Gliomas

Abstract BACKGROUND The concept of repeat radiotherapy for previously irradiated, progressive high-grade gliomas (PHGG) is intuitively rational for a disease that has the potential to be a life-threatening illness and seriously affect the quality of remaining life. Recently, a simplified method of prognosis prediction (the Heidelberg prognostic model/HPM) was developed to evaluate survival after re-irradiation of PHGGs. OBJECTIVE This retrospective study aimed to assess whether salvage stereotactic radiosurgery (SSRS) is worthwhile in patients with PHGGs, and to determine which individuals are likely to benefit from retreatment using the HPM. METHODS Three hundred eighty-three people were diagnosed with intracranial glioma between 2000 and 2010 at our institution. From this population, 25 patients (7%) who had a history of prior irradiation and underwent SSRS for PHGGs formed the subjects of this clinical audit. In the HPM system, scores were assigned for clinicopathological features such as age, histology and interval duration between treatments. There were five and 20 patients with HPM determined low and high prognostic scores, respectively. The mean follow-up period was 9.9 months. RESULTS Overall median survival (MS) was 7 months, and the 6, 12- and 24-months crude survival rates (CSR) were 60%, 28% and 16%, respectively. The MS and CSRs for the low scoring patients were 20 months, 100%, 100% and 20%, respectively; for the 20 high-scoring individuals, the corresponding findings were 8 months, 75%, 35% and 10%, respectively. Among the evaluable 11 people, the quality of life was acceptable in approximately half of the cases. Local recurrence rate after SSRS was 12%. Adverse-related events were not observed. CONCLUSION A trend towards improved survival was observed in the HPM low-scoring patients. More documentation of favorable effects is required to support the useful role of SSRS as second line treatment of PHGGs.

scholarly journals “Our Self-Undoing”: Christina Rossetti’s Literary and Somatic Expressions of Graves’ Disease

Humanities ◽  
2019 ◽  
Vol 8 (1) ◽  
pp. 57 ◽  
Author(s):  
Mary Arseneau ◽  
Emery Terrell
Keyword(s):  
Disease Process ◽  
Physical Symptoms ◽  
Graves Disease ◽  
Christina Rossetti ◽  
Her Family ◽  
New Rhetoric ◽  
Life Threatening Illness ◽  
Life Threatening ◽  
History Of

Victorian poet Christina Rossetti (1830–1894) was frequently troubled by poor health, and her mid-life episode of life-threatening illness (1870–1872) when she suffered from Graves’ disease provides an illuminating case study of the ways that illness can be reflected in poetry and prose. Rossetti, her family, and her doctors understood Graves’ disease as a heart condition; however, Rossetti’s writing reflects a different paradigm, presenting themes of self-attack and a divided self that uncannily parallel the modern understanding of Graves’ disease as autoimmune in nature. Interestingly, these creative representations reflect an understanding of this disease process that Rossetti family documents and the history of Victorian medicine demonstrate Rossetti could not have been aware of. When the crisis had passed, Rossetti’s writing began to include new rhetoric and imagery of self-acceptance and of suffering as a means of spiritual improvement. This essay explores the parallels between literary and somatic metaphors: Rossetti’s body and art are often simultaneously “saying” the same thing, the physical symptoms expressing somatically the same dynamic that is expressed in metaphor and narrative in Rossetti’s creative writing. Such a well-documented case history raises questions about how writing may be shaped by paradigms of illness that are not accessible to the conscious mind.

scholarly journals Philosophy of History of N.A. Berdyaev: The Existential End of History or an Apocalipsis Interiorized

2020 ◽  
pp. 35-42
Author(s):  
Artem Khamidulin ◽  
Keyword(s):  
Human Life ◽  
Opportunity To Learn ◽  
Philosophy Of History ◽  
Philosophy Of Time ◽  
Religious Philosophy ◽  
End Of History ◽  
The Past ◽  
Starting Point ◽  
History Of ◽  
The Moment

The article analyzes the philosophy of history of N. A. Berdyaev. The starting point of the article is the thesis about the relationship between the problematics of time and historical science. It is noted that for Berdyaev, the philosophy of time is one of the main themes of his philosophy of history. Attention is drawn to the feeling of dissatisfaction experienced by Berdyaev with the fluidity and mobility of time. The perception of the philosopher of time as solicitude and, to a large extent, as an evil or a disease that must be overcome is explicated. The reality of the past and future times equal to the present is revealed. The author demonstrates the bliss inspired by actual experience and philosophy of time. Concept of psychological time of Augustine, which justifies the reality of the past, present and future. Teaching about the instantaneity of the present as a point of interaction between time (historical and cosmic) and eternity (celestial time) of Berdyaev is considered. The possibility of experiencing this kind of moment is considered by Berdyaev on the basis of the existential dimension of time that flows in the depths of the human spirit. The author notes the influence of the teaching about the moment by Danish philosopher Sшren Kierkegaard on Berdyaev. A parallel is drawn between teaching on the meaning of the moment by Berdyaev and the concept of "kairos" of German theologian Paul Tillich. The article analyzes eschatology of Berdyaev, which determines his belonging to the traditions of the Russian religious philosophy of history. Two possible ways to overcome time are revealed: in an instant, i.e. repeatedly during human life, and as a result of the total end of history, which, according to Berdyaev, is also to a large extent a phenomenon of the existential sphere of being. According to Berdyaev, this kind of exit from time gives the opportunity to learn the meaning of history, on the one hand, and to free oneself from the enslaving power of time, on the other. It is concluded that Berdyaev understood the end of history existentially as a special spiritual experience that allows us to overcome time and look at history in terms of eternity.

Ostensible Versus Actual Reasons for Seeking Pediatric Attention: Another Look at the Parental Ticket of Admission

PEDIATRICS ◽  
1982 ◽  
Vol 70 (6) ◽  
pp. 870-874
Author(s):  
Lee W. Bass ◽  
Richard L. Cohen
Keyword(s):  
Family History ◽  
Chief Complaint ◽  
Parental Anxiety ◽  
Thought Processes ◽  
Pediatric Practice ◽  
Life Threatening Illness ◽  
Vital Functions ◽  
Sick Patient ◽  
Life Threatening ◽  
History Of

The presentation of parental anxiety that appears excessive in view of the nature of the child's "chief complaint" is a frequent occurrence in pediatric practice. This study reviews 370 sick-patient visits in one pediatric office during a three-month period. Additional questioning in the area of parental anxieties concerning these symptoms revealed that in 125 instances (33.8%), the parent was entertaining unverbalized fears that something much more serious was wrong with the child than could be anticipated from the ostensible reason for seeking assistance. An analysis of the "actual reason for coming" reveals that the child's presenting complaint has become associated for the parent with (1) family history of serious life-threatening illness; (2) fears of loss and separation; (3) death; (4) the fears of another family member who is pressing for "answers" about the problem; (5) fears of loss of vital functions and a variety of other thought processes that have somehow become linked to the child's symptom. Techniques for recognizing and ameliorating this parenting difficulty are discussed.

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