Introduction

Author(s):  
Frances Harris

This introduces the Marlborough-Godolphin partnership as not just a political alliance, but a close friendship founded on ideals of platonic love and heroic virtue. It reviews the various discourses of friendship, noting the cultural influences (the essayists Montaigne, Sir William Temple, Saint-Évremond, as well as heroic drama and opera) which carried the ideal forward, but with the growing sense that it must prove itself in actual human transactions. It suggests that studying the Marlborough-Godolphin friendship as it proved itself in war abroad and party conflict at home is revealing of two historical figures whom historians have often found enigmatic, though in the end their commitment to it contributed to their short-term failure as well as their longer-term success. The distinction between friendship and royal favour is also touched on.

Perfusion ◽  
2020 ◽  
pp. 026765912098222
Author(s):  
Yu Wang ◽  
Tengfei Qiao ◽  
Jun Zhou

Purpose: Type A acute aortic dissection (AAD) is an uncommon catastrophic cardiovascular disease with high pre-hospital mortality rate without timely and effectively treated. The aim of this study was to assess the value of serum platelet to hemoglobin (PHR) in predicting in-hospital mortality in type A AAD patients. Methods: A total of 183 type A AAD patients were included in this retrospective investigation from January 2017 to December 2019. Admission blood routine parameters were gathered and PHR was computed. The outcome was all-cause in-hospital mortality within 30 days. Results The average levels of serum PHR were significant higher in survivor group than those in non-survivor group (1.14 ± 0.57 vs 0.87 ± 0.47, p = 0.006) and serum PHR was an independent factor associated with in-hospital mortality (hazard ratio (HR): 2.831; 95% confidence interval (CI): 1.108–7.231; p = 0.030). ROC noted that 0.8723 was chosen as the ideal cutoff value with a sensitivity of 64.3% and specificity of 72.5%. In addition, the area under the ROC curve (AUC) was 0.693 (95% CI 0.599–0.787, p < 0.001). Conclusion: Admission serum PHR can be used as an independent predictor of in-hospital mortality in patients with type A AAD.


1976 ◽  
Vol 14 (8) ◽  
pp. 31-32

Attacks of asthma in most children are relatively mild, but in a few they are severe and potentially fatal.1 The severity of attacks can be reduced by β-adrenoceptor stimulants, theophylline compounds and sodium cromoglycate, but when these are not effective it may be necessary to give a corticosteroid continuously. For those children who develop a severe exacerbation despite maintenance treatment, or those who get infrequent but often severe attacks that do not respond to bronchodilators, a short high-dose course of a corticosteroid can be given, and many practitioners choose to give this to their patients at home.2 However since no trials of such treatment have been performed the benefit remains unproven.


2013 ◽  
Vol 18 (1) ◽  
pp. 50-60 ◽  
Author(s):  
Ruben Flores

The British socioemotional economy is marked by a tension between cosmopolitan humanitarian sentiments and the denial of sympathy for geographically close, but socially distant, strangers in need. The essence of this tension can be captured by the Dickensian notion of ‘telescopic philanthropy’. A proper understanding of this tension would benefit from examining both short-term and secular trends - proximate and distal causal mechanisms. The paper is not explanatory in nature, but aims to generate sensitizing concepts, while at the same time seeking to steer the altruism, morality, and social solidarity literature towards a more active engagement with history, power, and ideology.


Author(s):  
Anton Agus Setyawan ◽  
Fatchurrohman Fatchurrohman

There are two constraints in the process of economic recovery in Indonesia. First, investment rate is decreasing in the last five years. This matter happens due to the bad investment climate in Indonesia. Second, slow growth of export rate in Indonesia. At the present, investment rate in Indonesia is only 22 percent of GDP, while the ideal rate is 30 percent of GDP. Another problem, which may be interrupting the economic recovery, is de-industrialization. The sign of de-industrialization occur by relocation phenomena of FDIfrom Indonesia. This research analyze the effects of direct investment and export to GDP. The tool of analyses of this research is econometric model known as Error Correc­tion Models. The results shows that in a long term and short term, export and direct investment do not have a significant effect to GDP. It shows that Indonesia do not have a clear policy about export and investment. The policy implications of this research are government should have a deregulation policy in the industry and recover investment climate.


2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Matthew J Molloy ◽  
Wendy Shields ◽  
Molly W Stevens ◽  
Andrea C Gielen

Abstract Background Minor injuries are very common in the pediatric population and often occur in the home environment. Despite its prevalence, little is known about outcomes in children following minor injury at home. Understanding the impact of these injuries on children and their families is important for treatment, prevention, and policy. The objectives of our study were (1) To describe the distribution of short-term outcomes following pediatric minor injuries sustained at home and (2) To explore the relationship of injury type and patient and household demographics with these outcomes. Methods Children (n = 102) aged 0–7 years with a minor injury sustained at home were recruited in an urban pediatric emergency department as part of the Child Housing Assessment for a Safer Environment (CHASE) observational study. Each patient had a home visit following the emergency department visit, where five parent-reported outcomes were assessed. Relationships were explored with logistic regression. Results The most common type of injury was soft tissue (57.8 %). 13.2 % of children experienced ≥ 7 days of pain, 21.6 % experienced ≥ 7 days of abnormal activity, 8.9 % missed ≥ 5 days of school, 17.8 % of families experienced ≥ 7 days of disruption, and 9.1 % of parents missed ≥ 5 days of work. Families reported a total of 120 missed school days and 120 missed work days. Children who sustained a burn had higher odds of experiencing pain (OR 6.97), abnormal activity (OR 8.01), and missing school (OR 8.71). The parents of children who sustained a burn had higher odds of missing work (OR 14.97). Conclusions Families of children suffering a minor injury at home reported prolonged pain and changes in activity as well as significant school and work loss. In this cohort, burns were more likely than other minor injuries to have these negative short-term outcomes reported and represent an important target for interventions. The impact of these injuries on missed school and disruption of parental work warrants further consideration.


Author(s):  
Marko Attila Hoare

The Partisan movement in Bosnia-Hercegovina was the product both of long-term socio-economic developments at home and of the short-term ‘accident’ of foreign invasion and occupation; it involved the merger of a traditional Serb-peasant uprising and a modern urban-revolutionary movement; and it represented both a characteristic chapter and a turning-point in modern Bosnian history. The Axis powers of Germany and Italy, by destroying the Yugoslav kingdom, changed the course of Bosnian history. Their installation in power of the Ustasha regime, and the latter's genocide of the Serb population of Croatia and Bosnia-Hercegovina, unleashed a resistance movement that would take shape as the Partisans. Yet the Partisans were not simply an armed response to the new order, but a revolutionary movement of a specifically Bosnian kind.


Bioanalysis ◽  
2020 ◽  
Vol 12 (13) ◽  
pp. 971-976 ◽  
Author(s):  
Kevin P Bateman

Accessing patient samples using a whenever/wherever paradigm is needed to enable a better understanding of human biology and disease. The technology for convenient self-collection of blood samples by patients at home is quickly becoming available. The potential benefits of patient-centric sampling far outweigh the short-term challenges associated with implementation of this disruptive approach. This is especially true given we are amid a global pandemic and enabling patients to sample at home would help not only clinical trials, but healthcare in general. This perspective article aims to convince the reader that patient-centric sampling is a reality and that we are on the cusp of an information revolution in clinical trials that will be enabled by patient-centric (e.g., at home) sampling.


Jews at Home ◽  
2010 ◽  
pp. 295-300
Author(s):  
David Kraemer

This chapter is a response to the previous chapter's assumption that the development of Jews at home as an emotional concept is new by mining rabbinical sources to find precedent in Jewish tradition. Though it does not dismiss the arguments already made, the chapter asserts that the previous might be built upon too short-term a view of Jewish history. For most of the examples called upon to illustrate or bolster the previous chapter's arguments, here there are analogous historical examples that work to strengthen Judaism and the community of adherents. In fact, the lesson of Jewish history, and particularly of the rabbinic age, is that Jews should not inhibit themselves because of the fear of ultimate failure, because stasis itself could lead to stagnation and even death. It is today recognized by most historians of the period that the rabbis were originally a very small group. This means that, early on, their practices took centuries to become ‘traditional’. The chapter contends that it is arguably the rabbis' combining of the inherited with the boldly innovative that enabled Jews living in an age of challenge and frequent discomfort to survive as Jews into the coming era.


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