The endocrine system

2010 ◽  
Author(s):  
Yvonne Corcoran
Keyword(s):  
Endocrine System ◽  
Healthcare Setting ◽  
Endocrine Disorders ◽  
Local Policy ◽  
Endocrine Disorder ◽  
Anatomy And Physiology ◽  
Nursing Skills ◽  
Accurate Treatment ◽  
Cation System ◽  
The Uk

This chapter aims to explore the nursing skills required to care for the child and family with an underlying endocrine disorder both in a healthcare setting and in the community. This chapter will include an overview of the anatomy and physiology of the endocrine system, related pharmacology and microbiology, and a detailed description of the main skills involved in caring for children with an endocrine disorder and their families. Endocrine disorders in childhood are generally of a chronic nature, therefore prompt, accurate treatment and management are essential to ensure normal development into fully functioning adulthood. Disorders of the endocrine system can manifest their effects immediately or in a more gradual manner over days to months. Endocrine disorders most commonly occur due to three main reasons: a disordered endocrine system, often as a result of a genetic abnormality; overproduction of a particular hormone; or underproduction of a particular hormone (Evans & Tippins, 2008). Type 1 diabetes mellitus accounts for approximately 50% of endocrine disorders in childhood with an incidence in children (0–14 years) of 13.5 per 100,000 in the UK (Raine et al., 2006). Although some general principles apply to the nursing care of children with an endocrine disorder, you will need to refer to local policy and be familiar with local protocols regarding the nursing management of these children and their families in the hospital and the community. It is anticipated that you will be able to do the following once you have read and studied this chapter: ● Understand the anatomy and physiology of the endocrine system and how it affects many of our bodily functions. ● Understand the predominant pathological conditions related to the endocrine system. ● Understand the key nursing skills required to care for a child with an endocrine disorder and their family. The endocrine system is a chemical communi cation system that consists of hormone producing cells, hormones, and receptors (Glasper & Richardson, 2006). This system regulates and controls the body’s metabolic processes including energy production, growth, fluid and electrolyte balance, responses to stress, and sexual reproduction (Baxter et al., 2004).

scholarly journals Endocrine Disorders Accompanying Obesity - Effect or Cause?

2021 ◽  
Author(s):  
Alina Kurylowicz
Keyword(s):  
Weight Loss ◽  
Adipose Tissue ◽  
Endocrine System ◽  
Endocrine Disorders ◽  
Obese Patients ◽  
Endocrine Disorder ◽  
Adipose Tissue Dysfunction ◽  
Appropriate Treatment ◽  
Endocrine Organs ◽  
Simple Obesity

Endocrine disorders including hypothyroidism and hypercortisolism are considered as causes of secondary obesity. However, several hormonal abnormalities can also be found in individuals with primary (simple) obesity. Part of them results from the adipose tissue dysfunction that, via secreted adipokines, modulates the function of endocrine organs and can be reversed with weight loss. However, part of them correspond to the real endocrine disorder and require appropriate treatment. Therefore in the management of obese patients, it is essential to distinguish between obesity-related abnormal results of hormonal tests and underlying endocrine disorder. This chapter presents pathophysiological concepts of obesity-related changes in the endocrine system and briefly reviews diagnostic algorithms helpful in distinguishing them from the co-existing endocrine disorders.

scholarly journals Sepsis as a Pan-Endocrine Illness—Endocrine Disorders in Septic Patients

2021 ◽  
Vol 10 (10) ◽  
pp. 2075
Author(s):  
Weronika Wasyluk ◽  
Martyna Wasyluk ◽  
Agnieszka Zwolak
Keyword(s):  
Host Response ◽  
Peripheral Resistance ◽  
Endocrine System ◽  
Endocrine Disorders ◽  
Hormonal Changes ◽  
Adrenergic Stimulation ◽  
Hypothalamic Amenorrhea ◽  
Somatotropic Axis ◽  
Almost All ◽  
Triiodothyronine Concentration

Sepsis is defined as “life-threatening organ dysfunction caused by a dysregulated host response to infection”. One of the elements of dysregulated host response is an endocrine system disorder. Changes in its functioning in the course of sepsis affect almost all hormonal axes. In sepsis, a function disturbance of the hypothalamic–pituitary–adrenal axis has been described, in the range of which the most important seems to be hypercortisolemia in the acute phase. Imbalance in the hypothalamic–pituitary–thyroid axis is also described. The most typical manifestation is a triiodothyronine concentration decrease and reverse triiodothyronine concentration increase. In the somatotropic axis, a change in the secretion pattern of growth hormone and peripheral resistance to this hormone has been described. In the hypothalamic–pituitary–gonadal axis, the reduction in testosterone concentration in men and the stress-induced “hypothalamic amenorrhea” in women have been described. Catecholamine and β-adrenergic stimulation disorders have also been reported. Disorders in the endocrine system are part of the “dysregulated host response to infection”. They may also affect other components of this dysregulated response, such as metabolism. Hormonal changes occurring in the course of sepsis require further research, not only in order to explore their potential significance in therapy, but also due to their promising prognostic value.

Hydrogen and potassium regulation of (pro)renin processing and secretion

1994 ◽  
Vol 267 (1) ◽  
pp. F1-F12 ◽  
Author(s):  
J. A. King ◽  
J. C. Fray
Keyword(s):  
Diabetes Mellitus ◽  
Heart Disease ◽  
Surface Membrane ◽  
Endocrine System ◽  
Renin Secretion ◽  
Endocrine Disorders ◽  
K Channels ◽  
Human Renin ◽  
Cl Channels ◽  
H Channels

H and K ions play central roles in prorenin processing and secretion, and prorenin is abnormally expressed in H and K disorders. At the surface membrane of juxtaglomerular (JG) cells, K is sensed and regulated by K channels (coupled to Cl channels and activated by excess Ca), Na-K-adenosinetriphosphatase, and a KCl/H exchange transporter (regulated by Ca). In JG cell granular membrane, K flux is regulated by K channels and a KCl/H exchange transporter (activated by Ca). H channels and a H pump reside in the granular membrane, which maintain H concentration in the granular matrix at least two orders of magnitude greater than in cytosol. The H pump may also be responsible for maintaining the acidic matrix required for maximal prorenin processing to renin by prohormone convertase for human renin (PCren), the prorenin convertase. These molecules form the core of a chemiosmotic system, which appears to regulate both prorenin processing and renin secretion. Renin secretion and prorenin processing appear to be of more than causal significance in clinical disorders characterized by chemiosmotic imbalance. A critical review of the literature supports the following general conclusions. First, hyperrenin state defines the initial phase in the pathogenesis of heart disease, diabetes mellitus, and hypertension. Second, low-renin syndrome defines the transition-to-establish phase in the pathogenesis of heart disease, diabetes mellitus, and hypertension in which the key feature is renin secretory hyporesponsivity. Third, renin disorders are usually associated with other endocrine disorders (polyendocrinopathies types I, II, and III), suggesting that renin may be an important molecule in the processing of chemiosmotic forces. The key chemiosmotic molecules (K and H) are also important in the processing and export of most (if not all) hormones. Thus, by regulating K and H homeostasis, renin may regulate the endocrine system.

The Symptoms of Depression in Endocrine Disorders

CNS Spectrums ◽  
1999 ◽  
Vol 4 (4) ◽  
pp. 51-61 ◽  
Author(s):  
Burton Hutto
Keyword(s):  
Differential Diagnosis ◽  
Clinical Picture ◽  
Depressive Disorders ◽  
Depressive Illness ◽  
Endocrine Disorders ◽  
Endocrine Disorder ◽  
Presenting Symptoms ◽  
Symptoms Of Depression

AbstractMany endocrine disorders present with symptoms of depression, thus differentiating primary depressive disorders from such endocrine conditions can be challenging. Awareness of the typical clinical picture of endocrine disorders is of primary importance. This article discusses a variety of common and uncommon endocrine disorders and the symptomatology that might suggest a depressive illness, and reviews literature on how endocrinopathies can mimic depression. Emphasis is also placed on the role that stress can play in the pathogenesis of endocrine disorders. Psychiatrists should be familiar with the range of presenting symptoms for endocrine disorders, and they should not rely on the presence or absence of stressors to guide their differential diagnosis between depression and endocrine disorder.

scholarly journals New Labour and New Surveillance: Theoretical and Political Ramifications of CCTV Implementation in the UK

2002 ◽  
Vol 2 (2/3) ◽  
Author(s):  
Pete Fussey
Keyword(s):  
Fear Of Crime ◽  
Central Government ◽  
Local Level ◽  
Local Policy ◽  
Disciplinary Power ◽  
Structure And Agency ◽  
Surveillance Society ◽  
The Uk ◽  
Criminological Theories ◽  
The Impact

This paper examines the implications of New Labour's approaches to crime and disorder on CCTV implementation. It concentrates on the usage of CCTV as one of the government's many initiatives, which are intended to address crime and disorder, including the fear of crime. In particular, the impact of the 1998 Crime and Disorder Act (CDA) - the cornerstone of this government's approach to crime reduction - on the generation of such strategies is examined. The paper revisits neo-Marxist and Foucauldian analyses of the so-called surveillance society through an appraisal of the complex relationship between structure and agency in the formulation and implementation of anti-crime and disorder strategies. Drawing on fieldwork data the paper considers the activities of practitioners at a local level by focusing on the influence of central government, local communities and 'common sense' thinking based on certain criminological theories. It is argued that a myriad of micro-level operations, obligations, processes, managerial concerns (particularly conflict resolution and resource issues), structures and agency - as well as the indirect influence of central government - shape CCTV policy. Ultimately, the creation of new local policy contexts under the CDA emphasise the need to consider incremental and malleable processes concerning the formulation of CCTV policy. In turn, this allows a re-examination of theoretical accounts of surveillance, and their attendant assumptions of sovereign or disciplinary power.

The Endocrine System: Adrenal Glands

2017 ◽  
Author(s):  
Abbas Al-Kurd ◽  
Haggi Mazeh
Keyword(s):  
Adrenal Gland ◽  
Key Words ◽  
Patient Group ◽  
Clinical Relevance ◽  
Perioperative Management ◽  
Adrenal Glands ◽  
Preoperative Evaluation ◽  
Endocrine System ◽  
Anatomy And Physiology ◽  
Complicated Patient

The adrenal glands represent an essential component of the endocrine system, and their failure can have catastrophic consequences to several aspects of bodily homeostasis. Each adrenal gland can be divided into two different endocrine components, the cortex and the medulla, each with distinct functions. This in-depth review of normal adrenal embryology, anatomy, and physiology also emphasizes the clinical relevance of various irregularities in adrenal functioning. Every surgeon attempting to manage adrenal diseases is expected to be familiar with the detailed pathophysiology of these conditions because such an understanding is essential for sound preoperative evaluation and perioperative management of this potentially complicated patient group.  This review contains 4 figures, 1 table, and 70 references. Key words: adrenal, adrenal glands, adrenal pathophysiology, adrenal physiology, anatomy of adrenal glands, cortex, embryology, endocrine system, medulla

The Endocrine System: Adrenal Glands

2017 ◽  
Author(s):  
Abbas Al-Kurd ◽  
Haggi Mazeh
Keyword(s):  
Adrenal Gland ◽  
Key Words ◽  
Patient Group ◽  
Clinical Relevance ◽  
Perioperative Management ◽  
Adrenal Glands ◽  
Preoperative Evaluation ◽  
Endocrine System ◽  
Anatomy And Physiology ◽  
Complicated Patient

The adrenal glands represent an essential component of the endocrine system, and their failure can have catastrophic consequences to several aspects of bodily homeostasis. Each adrenal gland can be divided into two different endocrine components, the cortex and the medulla, each with distinct functions. This in-depth review of normal adrenal embryology, anatomy, and physiology also emphasizes the clinical relevance of various irregularities in adrenal functioning. Every surgeon attempting to manage adrenal diseases is expected to be familiar with the detailed pathophysiology of these conditions because such an understanding is essential for sound preoperative evaluation and perioperative management of this potentially complicated patient group.  This review contains 4 figures, 1 table, and 70 references. Key words: adrenal, adrenal glands, adrenal pathophysiology, adrenal physiology, anatomy of adrenal glands, cortex, embryology, endocrine system, medulla

The Endocrine System: Thyroid and Parathyroid

2019 ◽  
Author(s):  
Samantha J. Baker ◽  
John R. Porterfield Jr
Keyword(s):  
Venous Blood ◽  
Endocrine System ◽  
Superior Laryngeal Nerve ◽  
Central Compartment ◽  
Lymphatic Drainage ◽  
Laryngeal Nerve ◽  
Thyroid Disorders ◽  
Hormone Synthesis ◽  
Anatomy And Physiology ◽  
And Function

In the adult, the thyroid gland is located in the central compartment of the neck on the anterolateral aspect of the cervical trachea between the carotid sheaths. Patients with thyroid disorders require attentive care, and safe, successful surgery of the thyroid is dependent on an intimate knowledge of the anatomy and physiology of the gland. This review discusses nerve branches and function; arterial and venous blood supply; lymphatic drainage; histology; physiology; and thyroid hormone synthesis, secretion, and regulation. Nerve injuries and postoperative complications are summarized, as are functions of thyroid hormones. A thorough understanding of these relationships is imperative for proper medical recommendations, surgical procedure selection, and meticulous surgical technique to avoid complications. To provide safe care of patients with thyroid disorders, treating physicians must embrace the intricate details of the anatomy and physiology of this unique gland to avoid potentially devastating complications. This review contains 5 figures, 3 tables, and 29 references. Key Words: brachial cleft, lymphatic zones, recurrent laryngeal nerve, superior laryngeal nerve, nerve injury, thyroglossal duct cysts, thyroid, thyroidectomy

The Endocrine System: Adrenal Glands

2017 ◽  
Author(s):  
Abbas Al-Kurd ◽  
Haggi Mazeh
Keyword(s):  
Adrenal Gland ◽  
Key Words ◽  
Patient Group ◽  
Clinical Relevance ◽  
Perioperative Management ◽  
Adrenal Glands ◽  
Preoperative Evaluation ◽  
Endocrine System ◽  
Anatomy And Physiology ◽  
Complicated Patient

The adrenal glands represent an essential component of the endocrine system, and their failure can have catastrophic consequences to several aspects of bodily homeostasis. Each adrenal gland can be divided into two different endocrine components, the cortex and the medulla, each with distinct functions. This in-depth review of normal adrenal embryology, anatomy, and physiology also emphasizes the clinical relevance of various irregularities in adrenal functioning. Every surgeon attempting to manage adrenal diseases is expected to be familiar with the detailed pathophysiology of these conditions because such an understanding is essential for sound preoperative evaluation and perioperative management of this potentially complicated patient group.  This review contains 4 figures, 1 table, and 70 references. Key words: adrenal, adrenal glands, adrenal pathophysiology, adrenal physiology, anatomy of adrenal glands, cortex, embryology, endocrine system, medulla

Regional analgesia for Labour

2020 ◽  
pp. 237-272
Author(s):  
Sarah Harries ◽  
Rachel Collis
Keyword(s):  
Epidural Analgesia ◽  
Epidural Space ◽  
Regional Analgesia ◽  
Safety And Efficacy ◽  
Anatomy And Physiology ◽  
Technological Advances ◽  
The Uk

Epidural analgesia is the most effective way of managing pain associated with labour. Pharmacological and technological advances, as well as a greater understanding of anatomy and physiology, have contributed to its safety and efficacy, with >25% of women receiving epidural analgesia during labour in the UK today. The pharmacokinetics of drugs administered into the epidural space are explained, and the evidence for using different methods of administration to establish optimum analgesia, i.e. intermittent top-ups vs continuous infusions vs patient controlled epidural analgesia, is discussed. How to accurately assess a block is emphasized. Epidurals that do not work are a source of anxiety and frustration to women and anaesthetists alike. Therefore understanding why an epidural may not behave as expected, and suggestions to trouble-shoot problematic epidurals are described based on authors’ experience.

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