THE RELATIONSHIP BETWEEN DIABETES AND OBESITY: A STUDY OF SUSCEPTIBILITY TO DIABETES IN OBESE PEOPLE

QJM ◽  
1965 ◽  
Keyword(s):  
Obese People ◽  
The Relationship ◽  
Diabetes And Obesity

FABP1 gene variant associated with risk of metabolic syndrome

2021 ◽  
Vol 24 ◽  
Author(s):  
Reza Zare-Feyzabadi ◽  
Majid Mozaffari ◽  
Majid Ghayour-Mobarhan ◽  
Mohsen Valizadeh
Keyword(s):  
Metabolic Syndrome ◽  
International Diabetes Federation ◽  
Amplification Refractory Mutation System ◽  
Study Cohort ◽  
Increased Risk ◽  
Mutation System ◽  
Polymerase Chain ◽  
The Relationship ◽  
Diabetes And Obesity

Background: Metabolic Syndrome (MetS) is defined by a clustering of metabolic abnormalities associated with an increased risk of cardiovascular disease and type 2 diabetes mellitus. There has been an increasing interest in the associations of genetic variants involved in diabetes and obesity in the FABP1 pathway. The relationship between the rs2241883 polymorphism of FABP1 and risk of MetS remains unclear. Objective: We aimed to examine the association between this genetic polymorphism and the presence of MetS and its constituent factors. Methods: A total of 942 participants were recruited as part of the Mashhad Stroke and Heart Atherosclerosis Disorders (MASHAD study) Cohort. Patients with MetS were identified using the International Diabetes Federation (IDF) criteria (n=406) and those without MetS (n=536) were also recruited. DNA was extracted from peripheral blood samples and used for genotyping of the FABP1 rs2241883T/C polymorphism using Tetra-Amplification Refractory Mutation System Polymerase Chain Reaction (Tetra-ARMS PCR). Genetic analysis was confirmed by gel electrophoresis and DNA sequencing. Results: Using both univariate and multivariate analyses after adjusting for age, sex and physical activity, carriers of C allele (CT/CC genotypes) in FABP1 variant were related to an increased risk of MetS, compared to non-carriers (OR: 1.38, 95%CI: 1.04,1.82, p=0.026). Conclusion: The present study shows that C allele in the FABP1 variant can be associated with an increased risk of MetS. The evaluation of these factors in a larger population may help further confirm these findings.

THU0504 The Relationship Between Weight Loss and Reduced Cartilage Loss in the Medial Knee Joint is Non-Linear in Obese People

2013 ◽  
Vol 72 (Suppl 3) ◽  
pp. A334.1-A334
Author(s):  
A. Wluka ◽  
A. Teichtahl ◽  
S. Tanamas ◽  
Y. Wang ◽  
B. Strauss ◽  
...  
Keyword(s):  
Weight Loss ◽  
Knee Joint ◽  
Cartilage Loss ◽  
Obese People ◽  
Medial Knee ◽  
Non Linear ◽  
The Relationship

scholarly journals Overweight and obesity in 16–18 years old teenagers in South Jakarta and the relationship with academic performance

2020 ◽  
Vol 4 (1-3) ◽  
pp. 38
Author(s):  
Marie Christabelle ◽  
Bernie Endyarni Medise
Keyword(s):  
Academic Performance ◽  
Cross Sectional Study ◽  
Overweight And Obesity ◽  
Sectional Study ◽  
Obese People ◽  
Chi Square ◽  
Cross Sectional ◽  
Chi Square Test ◽  
The Relationship ◽  
Academic Year

Objective: In different parts of the world, Indonesia included, overweight and obese people are seen to have worse performance compared to their healthy counterparts. Although there were research that had been done to observe the relationship between overweight, obesity, and academic performance, the results obtained were still divided into significantly and non-significantly related.Methods: A cross-sectional study was done to 373 students from two different schools in South Jakarta on December 2017–January 2018. Data was obtained by measuring height and weight of the participant to get his/her nutritional status and the average of participant’s odd semester Continual Assessment and Semestral Assessment of Academic Year 2017/2018 to see if the result was higher or equal to the passing grade.Results: Data analysis with chi square test shows that there was no significant relationship between overweight, obesity, and academic performance (p = 0.452 for Indonesian Language and p = 0.476 for Mathematics) although overweight and obese students tend to have better performance in some exam.Conclusion: The events that lead to overweight, obesity, and one’s academic performance are all multifactorial that the relationship between the two is difficult to be determined.

Hydration and obesity among outpatient-based population: H2Ob study

2018 ◽  
Vol 66 (4) ◽  
pp. 780-783
Author(s):  
Juana Carretero-Gómez ◽  
Jose Carlos Arévalo Lorido ◽  
Ricardo Gómez Huelgas ◽  
Begoña De Escalante Yangüela ◽  
Borja Gracia Tello ◽  
...  
Keyword(s):  
Weight Status ◽  
Cross Sectional Study ◽  
Hydration Status ◽  
Urine Osmolarity ◽  
Plasma Osmolarity ◽  
Obese People ◽  
Cross Sectional ◽  
Treatment Of Obesity ◽  
Few Data ◽  
The Relationship

Recent evidence suggests that obese people are hypohydrated and that water consumption may be a useful indicator for the prevention and treatment of obesity. Nevertheless, there is no agreement regarding the best hydration status indicators and there are few data about the relationship between hydration and body weight. In the present study, we aim to analyze the correlation among hydration status with obesity measured by three different methods (plasma osmolarity, urinary specific gravity (USG) and urinary osmolarity) in a hospital-based outpatient population. We have carried out a cross-sectional study to evaluate the association between obesity and hydration status in 260 patients, average 56.5±15.7 years. Hydration status was estimated by means of plasma osmolarity, urine osmolarity and USG. We did show significant trend of higher urine osmolarity (P=0.03), USG (P=0.000) and plasma osmolarity (P=0.000) with an increase of weight status categories, more accurate in the case of plasma osmolarity. In a multivariate analysis, after controlled by confounders, we found that obesity was associated with plasma osmolarity (OR 1.09; 95% CI 1.02 to 1.17, P=0.009), urine osmolarity (OR 1.00; 95% CI 1.00 to 1.01, P=0.05) and USG (OR 1.02; 95% CI 1.00 to 1.04, P=0.05). Our results have shown a more accurate relationship between plasma osmolarity with all body mass index categories. This finding may have clinical implications that must be confirmed in further studies.

scholarly journals CARACTERÍSTICAS FÍSICO-QUÍMICAS (Passiflora) ELABORADO COM SUBSTITUTOS DE GORDURAS

2000 ◽  
Vol 18 (2) ◽  
Author(s):  
DANIELLE SELL DYMINSKI ◽  
NINA WASZCYNSKYJ ◽  
ROSEMARY H. RIBANI ◽  
MARIA LÚCIA MASSON
Keyword(s):  
Passion Fruit ◽  
Formulation Development ◽  
Obese People ◽  
Caloric Value ◽  
Energy Value ◽  
Medical Area ◽  
Fat Substitutes ◽  
The Relationship

A relação entre a ingestão de gorduras e a saúde tem sido debatida exaustivamente na área médica. A necessidade de redução da quantidade de gordura na alimentação motivou este estudo, que visou o desenvolvimento de formulação para musse de maracujá, com menor teor de gordura e de valor calórico, utilizando substitutos de gordura. No musse de maracujá padrão empregouse creme de leite integral, contendo em média 24,95 % de lipídios e nos musses formulados com substitutos da gordura foram utilizados a polidextrose (Litesse-PFIZER), proteína derivada do leite (Dairy-Lo-PFIZER) e proteína microparticulada (Simplesse Dry 100- NUTRASWEET). Empregou-se a proteína microparticulada e a polidextrose isoladamente e as seguintes combinações: proteína microparticulada/ polidextrose; proteína derivada do leite/polidextrose e proteína derivada do leite/polidextrose/proteína microparticulada. Os musses foram analisados físicoquimicamente de acordo com as normas analíticas do Instituto Adolfo Lutz. Entre os musses formulados com substitutos de gordura constatouse redução de 40,5% no valor energético e 93,6% de gordura em comparação ao mousse de maracujá padrão. Tais produtos podem ser classificados como “light”, tanto em relação ao valor energético como ao teor de gordura, sendo possível sua indicação como alimento adequado para pessoas preocupadas com a saúde e/ou obesas. Abstract The relationship between the ingestion of fats and the health has been extensively debated in the medical area. The reduction need of fat amount in feeding motivated this study, that sought the formulation development for passion fruit mousse with smaller fat text and of caloric value using fat substitutes. In the standard passion fruit mousse it was used integral milk cream, containing 24,95% of lipids on average and in the mousses formulated with fat substitutes the polidextrose was used (LitessePFIZER), milk derived (Dairy-Lo-PFIZER) and protein microparticulated (Simplesse Dry 100- ­NUTRASWEET). It was used the microparticulated protein and the polidextrose separately and in the following combinations: microparticulated protein/polidextrose; milk derived protein/polidextrose and milk derived protein/polidextrose/microparticulated protein. The mousses were analyzed physicalchemically in agreement with the Analytic Norms of the Instituto Adolfo Lutz. Among the mousses formulated with fat substitutes it was verified a reduction of 40,5% in the energy value and 93,6% of fat in comparison to the standard mousse. Such products can be classified as "light", as well to the energy value as to the fat text, being its indication possible as food adapted for obese people and peolpe worried with health.

Well-Being and Prejudice toward Obese People in Women at Risk to Develop Eating Disorders

2012 ◽  
Vol 15 (3) ◽  
pp. 1293-1302 ◽  
Author(s):  
Alejandro Magallares
Keyword(s):  
Eating Disorders ◽  
Well Being ◽  
Eating Attitudes ◽  
Depression And Anxiety ◽  
Obese People ◽  
Oral Control ◽  
Weight Problems ◽  
Eat 26 ◽  
The Relationship ◽  
Antifat Attitudes

The literature has found that eating disorders (ED) patients usually have a depression and anxiety diagnosis. However, not many investigations have studied the relationship between ED and well-being. One of the main problems of patients with ED is their body image. These individuals usually see themselves too big but there are not many investigations that focus on how these patients see people with real weight problems. For this reason in this study it is analyzed how women in risk to develop ED see obese people. 456 female students were selected. It was found that women with high scores in the different subscales of the Eating Attitudes Test 26 (EAT-26; dieting, bulimia and oral control) had lower well-being (both subjective and psychological) and worse attitudes toward obese people (measured with Antifat Attitudes Test, AFA, Beliefs About Obese People Scale, BAOP, and Attitudes Toward Obese People Scale, ATOP) compared with women with low scores in the EAT-26.

The Relationship Between Different Body Mass Index Categories and Chair Rise Performance in Adult Women

2013 ◽  
Vol 29 (6) ◽  
pp. 705-711 ◽  
Author(s):  
Stefan Schmid ◽  
Stéphane Armand ◽  
Zoltan Pataky ◽  
Alain Golay ◽  
Lara Allet
Keyword(s):  
Adult Women ◽  
Life Activity ◽  
Obese People ◽  
Stand Test ◽  
Sit To Stand ◽  
Severely Obese ◽  
Obese Subjects ◽  
Chair Rise ◽  
The Relationship ◽  
Overweight Subjects

An important prerequisite to carry out daily activities is the sit-to-stand movement. However, in obese people, this movement is characterized by altered biomechanics, which might lead to daily life activity impairments. The aim of this study was to investigate whether there are differences in kinetic and kinematic variables between three different BMI categories when performing a specific sit-to-stand test. Thirty-six adult women (BMI = 17–45 kg/m2) performed the sit-to stand test five times consecutively and as quickly as possible. Analyses of variance were used to determine differences between three BMI groups (normal or overweight: BMI < 30 kg/m2; obese: 30 ≤ BMI < 35; severely obese: BMI ≥ 35). Peak and mean vertical sacrum velocity indicated a decrease in severely obese subjects. Obese and severely obese individuals did not show higher fatigue over the five consecutive movements. Peak force and rate of force development decreased in normal or overweight subjects. The ability to successfully complete the test decreased with a higher BMI, probably due to a reduced ability to rapidly generate a high force.

Obesity in young adulthood and later disability pension: A population-based cohort study of 366,929 Swedish men

2007 ◽  
Vol 35 (1) ◽  
pp. 48-54 ◽  
Author(s):  
Nina Karnehed ◽  
Finn Rasmussen ◽  
Malin Kark
Keyword(s):  
Cohort Study ◽  
Marital Status ◽  
Young Adulthood ◽  
Socioeconomic Position ◽  
Disability Pension ◽  
Parental Education ◽  
Cox Regression ◽  
Population Based ◽  
Obese People ◽  
The Relationship

Background: The prevalence of obesity has increased threefold among Swedish men during recent decades. Knowledge from Sweden on how obese men manage in working life and become disability pensioners is sparse. The aim of this nationwide and population-based cohort study was to investigate to what extent body mass index (BMI) in young adulthood predicts later disability pension. Method: All Swedish men born 1952—59, who had their weight and height measured at age 18 years in the compulsory military conscription examinations, were followed up longitudinally from 1990 to 2001 with regard to receiving disability pension. Data on own socioeconomic position (1985), education and marital status (1990), parental socioeconomic position (1960), and education (1970) were obtained from censuses. For 366,929 men (81% of the eligible men) the hazard ratio for receiving disability pension was calculated with Cox regression controlling for own education, parental education, childhood and adult socioeconomic position, marital status, morbidity, and type of municipality. Results: Obesity in young adulthood increased the risk for disability pension later in life (1.35, 95% CI 1.19, 1.52) compared with men of normal weight. The relationship between BMI and disability pension was J-shaped with higher risks for underweight (1.14, 95% CI 1.09, 1.20) and obese men. Conclusions: Obese men in Sweden are at higher risk of receiving disability pension. The relationship between BMI and disability pension is J-shaped. An important future task is to estimate the societal costs due to disability pension of obese people.

scholarly journals INTERLEUKIN LEVELS IN PATIENTS WITH ESSENTIAL HYPERTENSION COMBINED WITH TYPE 2 DIABETES MELLITUS

2019 ◽  
Vol 6 (1) ◽  
pp. 38-42
Author(s):  
B.O. Shelest
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Essential Hypertension ◽  
Interleukin 6 ◽  
Inflammatory Marker ◽  
Cardiovascular Complications ◽  
The Relationship ◽  
Diabetes And Obesity

INTERLEUKIN LEVELS IN PATIENTS WITH ESSENTIAL HYPERTENSION COMBINED WITH TYPE 2 DIABETES MELLITUSShelest B.O.The problem of combined course of hypertension of diabetes mellitus type 2 and obesity is becoming more common. This variant of comorbidity crucially increases the risk of cardiovascular complications. Inflammation is considered as an important link between the progression of hypertension and the development of adverse events. This study is devoted to the question of the relationship between the pro-inflammatory marker interleukin-6 and the increased blood pressure in patients with concomitant diabetes and obesity. The treatment of such patients with combined pathology remains the actual and difficult issue of medical practice. The article analyses the dynamics of interleukin-6 in the process of treatment with a fixed triple antihypertensive combination. Key words: hypertension, interleukin-6, type 2 diabetes mellitus, obesity. РІВНІ ІНТЕРЛЕЙКІНІВ У ХВОРИХ НА ГІПЕРТОНІЧНУ ХВОРОБУ У ПОЄДНАННІ З ЦУКРОВИМ ДІАБЕТОМ 2 ТИПУ Шелест Б.О.Все більшого поширення набуває проблема поєднаного перебігу гіпертензії цукрового діабету 2 типу та ожиріння. Такий варіант коморбидности різко підвищує ризик кардіоваскулярних ускладнень. Важливою ланкою в прогресуванні гіпертензії і розвитку несприятливих подій відводиться запаленню. Дана робота присвячена питанню залежності прозапального маркера інтерлейкіну-6 і підвищених цифр артеріального тиску у хворих з супутнім цукровим діабетом 2 типу і ожирінням. Актуальним і складним питанням медичної практики залишається лікування таких пацієнтів з поєднаною патологією. У статті аналізується динаміка інтерлейкіну-6 в процесі лікування потрійною фіксованою антигіпертензивною комбінацією.Ключові слова: гіпертонічна хвороба, інтерлейкін-6, цукровий діабет 2 типу, ожиріння. УРОВЕНЬ ИНТЕРЛЕЙКИНОВ У ПАЦИЕНТОВ С ГИПЕРТОНИЧЕСКОЙ БОЛЕЗНЬЮ В СОЧЕТАНИИ С САХАРНЫМ ДИАБЕТОМ 2 ТИПА. Шелест Б.А.Все большее распространение приобретает проблема сочетанного течения гипертензии сахарного диабета 2 типа и ожирения. Такой вариант коморбидности резко повышает риск кардиоваскулярных осложнений. Важным звеном в прогрессировании гипертензии и развитии неблагоприятных событий отводится воспалению. Даннаяработапосвящена вопросу зависимости провоспалительного маркера интерлейкина-6 и наличием повышенных цифр артериального давления у больных с сопутствующим сахарным диабетом и ожирением. Актуальным и сложным вопросом медицинской практики остается лечение таких пациентов с сочетанной патологией. В статье анализируется динамика интерлейкина-6 в процессе лечения фиксированной тройной антигипертензивной комбинацией. Ключевые слова: гипертоническая болезнь, интерлейкин-6, сахарный диабет 2 типа, ожирение.

Sign in / Sign up

Export Citation Format

Share Document