scholarly journals Low-field thoracic magnetic stimulation increases peripheral oxygen saturation levels in coronavirus disease (COVID-19) patients

Medicine ◽  
2021 ◽  
Vol 100 (40) ◽  
pp. e27444
Author(s):  
Saul M. Dominguez-Nicolas ◽  
Elias Manjarrez
2021 ◽  
Author(s):  
Saul M Dominguez-Nicolas ◽  
Elias Manjarrez

The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) may cause low oxygen saturation (SpO2) and respiratory failure in coronavirus disease (COVID-19) patients. Hence the increase of SpO2 levels could be crucial for the quality of life and recovery of these patients. Here we introduce an electromagnetic device termed low-field thoracic magnetic stimulation (LF-ThMS) system. This device was designed to non-invasively deliver a pulsed magnetic field from 100 to 118 Hz and 10.5 to 13.1 mT (i.e., 105 to 131 Gauss) to the dorsal thorax. We show that these frequencies and magnetic flux densities are safe for the patients. We also present a proof-of-concept that a single session of LF-ThMS applied for 30 minutes to the dorsal thorax of 17 COVID-19 patients significantly increases their SpO2 levels. We designed a single-blind, sham-controlled, crossover study on 5 COVID-19 patients who underwent two sessions of the study (real and sham LF-ThMS) and 12 COVID-19 patients who underwent only the real LF-ThMS. We found a statistically significant correlation between magnetic flux density, frequency, or temperature associated with the real LF-ThMS and SpO2 levels in all COVID-19 patients. However, the five patients of the sham-controlled study did not exhibit a significant change in their SpO2 levels during sham stimulation. All the patients did not present adverse events after the LF-ThMS intervention.


Respirology ◽  
2009 ◽  
Vol 14 (4) ◽  
pp. 537-544 ◽  
Author(s):  
Audrey BORGHI-SILVA ◽  
Luciana DI THOMMAZO ◽  
Camila B.F. PANTONI ◽  
Renata G. MENDES ◽  
Tania DE FÁTIMA SALVINI ◽  
...  

2021 ◽  
Author(s):  
Hoi Lam Ng ◽  
Johannes Trefz ◽  
Martin Schönfelder ◽  
Henning Wackerhage

Abstract Background: Face masks are an effective, non-pharmacological strategy to reduce the transmission of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) and other pathogens. However, it is a challenge to keep masks sealed during exercise, as ventilation can increase from 5-10 L/min at rest to up to 200 L/min so that masks may be blown away from the face. To reduce leakage e.g. during exercise, a face mask was developed that is taped onto the face. The aim of this study was to investigate during a graded cycle ergometry test the effect of a taped mask on the perception of breathlessness, heart rate, lactate, and oxygen saturation when compared to a surgical mask and no mask.Methods: Four trained and healthy males and females each (n=8 in total) performed incremental cycle ergometer tests until voluntary exhaustion under three conditions: (1) No mask/control, (2) surgical mask or (3) taped mask. During these tests, we measured perception of breathlessness, heart rate, the concentration of blood lactate and peripheral oxygen saturation and analysed the resultant data with one or two-way repeated measures ANOVAs. We also used a questionnaire to evaluate mask comfort and analysed the data with paired t-tests. Results: When compared to wearing no mask, a taped face mask significantly reduces the maximal workload in a graded exercise test by 12±6% (p=0.001). Moreover, with a taped face mask, subjects perceive severe breathlessness at 12±9% lower workload (p=0.012) and oxygen saturation at 65% of the maximal workload is 1.5% lower (p=0.018) when compared to wearing no mask. Heart rate and the concentration of lactate were not significantly different at any workload. When compared to wearing a surgical mask, wearing a taped face mask has a significantly better wearing comfort (p=0.038), feels better on the skin (p=0.004), there is a lower sensation of moisture (p=0.026) and wearers perceive that less heat is generated (p=0.021). We found no sex/gender differences for any parameters. Conclusions: A taped mask is well tolerated during light and moderate exercise intensity but reduces maximal exercise capacity.


2018 ◽  
Vol 59 (3) ◽  
pp. 1-8
Author(s):  
Elly Morros González ◽  
Diana Estrada Cano ◽  
Marcela Murillo Galvis ◽  
Jos Carlos Montes Correa ◽  
Nelcy Rodríguez Malagón ◽  
...  

Introduction: Supplemental oxygen is considered a pharmaceutical drug; therefore, it can produce adverse effects. Lack of consensus regarding the reading of oxygen flowmeters and the peripheral oxygen saturation (SpO2) goals can influence clinical and paraclinical decisions and hospital stay length. Objective: To assess knowledge on oxygen therapy, adverse effects, SpO2 goals and reading of oxygen flowmeters among personnel in the Pediatric Unit at Hospital Universitario San Ignacio, Bogotá, Colombia. Methodology: Cross-sectional study derived from convenience sampling through a self-applied survey between December 2016 and January 2017. The poll evaluated topics on supplemental oxygen therapy fundamentals and adverse effects, SpO2 goals and flowmeter readings through flowmeters photographs indicating a specific fraction of inspired oxygen (FiO2). Results: The response rate was 77% from 259 subjects. 22% considered that the oxygen saturation either increases or remains the same during sleep periods in children. 78% of participants knew at least one complication associated to prolonged oxygen therapy and 67% due to supplemental oxygen concentration greater than required. In neonatal population, 10% considered oxygen saturation goals equal to or greater than 96%. In the flowmeter’s reading evaluation, incorrect answers ranged from 9 to 19%. Conclusion: It is imperative to reinforce updated concepts on oxygen therapy, with emphasis in SpO2 goals, adverse effects and appropriate flowmeter’s readings through periodic educational campaigns.


2017 ◽  
Vol 10 (2) ◽  
pp. 425
Author(s):  
M.J. Dubin ◽  
A.A. Cochran ◽  
C.G. Gross ◽  
J.P. Dyke ◽  
H.U. Voss ◽  
...  

2019 ◽  
Vol 249 ◽  
pp. 286-293 ◽  
Author(s):  
Marc J. Dubin ◽  
Irena P. Ilieva ◽  
Zhi-De Deng ◽  
Jeena Thomas ◽  
Ashly Cochran ◽  
...  

2012 ◽  
Vol 20 (6) ◽  
pp. 1169-1175
Author(s):  
Walkiria Shimoya-Bittencourt ◽  
Carlos Alberto de Castro Pereira ◽  
Solange Diccini ◽  
Ana Rita de Cássia Bettencourt

AIM: To assess the interference of nail polish on the reading of peripheral oxygen saturation in patients with chronic obstructive pulmonary disease on the step exercise. METHODS: In this study, there was the inclusion of patients with chronic obstructive pulmonary disease, current non-smokers, of both sexes. Four different colours of nail polish were used in the present study (base, light pink, red and brown), randomly distributed among the fingers of the right hand, with the corresponding fingers on the opposite hand being controls. Saturation was measured at rest, with and without the polish, and also during the 4th, 5th and 6th minutes of the exercise programme. RESULTS: The experimental universe included 42 patients with ages of 62.9±8.7 years. In the exercise considered, the red colour reduced it in the fourth minute of the exercise (p=0.047). In contrast, the brown colour reduced saturation at rest and also during the course of exercise (p=0.01). CONCLUSION: In patients with chronic obstructive pulmonary disease, the red and brown colours interfered with the reading of the peripheral oxygen saturation during exercise. This study is registered at the Brazilian Register of Clinical Trials (Registro Brasileiro de Ensaios Clínicos) under No. RBR-9vc722.


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