Changes of Body Composition in Bulimia Nervosa: Increased Visceral Fat and Adrenal Gland Size

2009 ◽  
Vol 71 (1) ◽  
pp. 93-97 ◽  
Author(s):  
Burkhard Ludescher ◽  
Gabriele Leitlein ◽  
Jacques-Emmanuel Schaefer ◽  
Stefanie Vanhoeffen ◽  
Sophia Baar ◽  
...  
2014 ◽  
Vol 25 (3) ◽  
pp. 443-451 ◽  
Author(s):  
Alberto Bazzocchi ◽  
Federico Ponti ◽  
Stefano Cariani ◽  
Danila Diano ◽  
Luca Leuratti ◽  
...  

Author(s):  
Lauren C. Chasland ◽  
Bu B Yeap ◽  
Andrew J. Maiorana ◽  
Yi X Chan ◽  
Barbara A Maslen ◽  
...  

As men age, serum testosterone (T) concentrations decrease, as do fitness, strength and lean mass. Whether testosterone treatment confers additive benefit to reverse these changes when combined with exercise training in middle-to-older aged men remains unclear. We assessed the effects of T treatment and exercise, alone and in combination, on aerobic capacity (VO2peak), body composition and muscular strength in men 50-70yrs, waist circumference ≥95cm and low-normal serum T (6-14nmol·L−1). Participants (n=80) were randomised to AndroForte5® (Testosterone 5.0%w/v, 100mg/2mL) cream (T), or matching placebo (P), applied transdermally daily, and supervised centre-based exercise (Ex) or no additional exercise (NEx), for 12-weeks. Exercise increased VO2peak and strength vs non-exercise (VO2peak: T+Ex:+2.5, P+Ex:+3.2mL·kg−1·min−1, P<0.001; leg press: T+Ex:+31, P+Ex:+24kg, P=0.006). T treatment did not affect VO2peak or strength. Exercise decreased total (T+Ex:-1.7, P+Ex-2.3kg, P<0.001) and visceral fat (T+Ex:-0.1, P+Ex:-0.3kg, P=0.003), and increased total (T+Ex:+1.4, P+Ex:+0.7kg, P=0.008) and arm lean mass (T+Ex:+0.5, P+Ex:+0.3kg, P=0.024). T treatment did not affect total or visceral fat, but increased total (T+Ex:+1.4, T+NEx:+0.7kg, P=0.015), leg (T+Ex:+0.3, T+NEx:+0.2kg, P=0.024) and arm lean mass (T+Ex:+0.5, T+NEx:+0.2kg, P=0.046). T+Ex increased arm lean mass (T+Ex:+0.5kg vs P+NEx:-0.0kg, P=0.001) and leg strength (T+Ex:+31 vs P+NEx:+12kg, P=0.032) compared to P+NEx, with no other additive effects. Exercise training was more effective than T treatment in increasing aerobic capacity and decreasing total and visceral fat mass. T treatment at therapeutic doses increased lean mass but conferred limited additional benefit when combined with exercise. Exercise should be evaluated as an anti-ageing intervention in preference to testosterone treatment in men.


2014 ◽  
Vol 43 (1) ◽  
pp. 139-148 ◽  
Author(s):  
Helena Moreira ◽  
Betânia Passos ◽  
Josiane Rocha ◽  
Vivianne Reis ◽  
André Carneiro ◽  
...  

Abstract The object of the study was to analyze the relationship between aerobic fitness and body composition in postmenopausal women. We hypothesized that postmenopausal women that had higher adiposity had lower cardiorespiratory capacity, regardless of the characteristics of menopause. The sample included 208 women (57.57 ± 6.62 years), whose body composition and the basal metabolic rate were evaluated by octopolar bioimpedance (InBody 720) and the oxygen uptake by the modified Bruce protocol. Most of the sample showed obesity and a high visceral fat area. The visceral fat area and the basal metabolic rate explained 30% of the variation of oxygen uptake, regardless of age, time, nature or hormone therapy. The values of the latter variables were reduced in the presence of high central adiposity (-6.16 ml/kg/min) and the basal metabolic rate of less than 1238 kcal/day (-0.18 ml/kg/min). The women with oxygen uptake above 30.94 ml/kg/min showed lower values of total and central adiposity when compared with other groups. With an increase of aerobic fitness, there was a growing tendency of the average values of the soft lean mass index, with differences between the groups low-high and moderate-high. These results suggest worsening of the cardiorespiratory condition with an increase of central adiposity and a decrease of the BMR, regardless of age and menopause characteristics.


Endocrine ◽  
2021 ◽  
Author(s):  
Mariangela Rondanelli ◽  
Simone Perna ◽  
Zahra Ilyas ◽  
Gabriella Peroni ◽  
Philip Bazire ◽  
...  

Abstract Purpose This study aims to evaluate the effects of a VLCKD combined with omega-3 supplementation (VLCKD diet only lasted for some weeks, and it was followed by a non-ketogenic LCD for the rest of the study period) on body composition, visceral fat, satiety hormones, inflammatory and metabolic markers. Methods It has been performed a pilot open label study lasted 90 days, in a cohort of 12 women with class I obesity aged 18 to 65 years. Data on body composition (evaluated by Dual X-Ray Absorptiometry—DXA), visceral fat, satiety hormones, inflammatory and metabolic markers were recorded. Results This study showed a body weight reduction mean difference over time of −13.7 kg and the waist circumference mean difference decrease of −13.3 cm. Also, the fat mass (FM) decreased—9.1 kg and visceral adipose tissue (VAT)—0.41 kg. No effects on fat-free mass (FFM) have been reported. Improvements were observed in the satiety hormones, with increased ghrelin and decreased leptin, and also in the metabolic profiles. Conclusions A VLCKD combined with omega-3 supplementation appears to be an effective strategy for promoting an high loss of FM with preservation of FFM in patients with class I obesity.


2021 ◽  
Author(s):  
Danae Delivanis ◽  
Maria Daniela Hurtado Andrade ◽  
Tiffany Cortes ◽  
Shobana Athimulam ◽  
Aakanksha Khanna ◽  
...  

Objective: Increased visceral fat and sarcopenia are cardiovascular risk factors that may explain increased cardiovascular morbidity and frailty in patients with adrenal adenomas. Our objective was to compare body composition measurement of patients with adrenal adenomas to referent subjects without adrenal disease Design: Cross-sectional study, 2014-2018 Methods: Participants were adults with nonfunctioning adrenal tumor (NFAT), mild autonomous cortisol secretion (MACS) and Cushing syndrome (CS), and age, sex and body mass index 1:1 matched referent subjects without adrenal disorders. Main outcome measures were body composition measurements calculated from abdominal computed tomography imaging. Intraabdominal adipose tissue and muscle mass measurements were performed at the 3rd lumbar spine level. Results: Of 227 patients with adrenal adenomas, 20 were diagnosed with CS, 76 with MACS and 131 with NFAT. Median age was 56 years (range, 18-89), and 67% were women. When compared to referent subjects, patients with CS, MACS, and NFAT demonstrated a higher visceral fat (odds ratio (OR) of 2.2 [95% CI 0.9-6.5], 2.0 [1.3-3.2], and 1.8 [1.2-2.7] and a lower skeletal muscle area (OR of 0.01 [95% CI 0-0.09], 0.31 [0.18-0.49], and 0.3 [1.2-2.7]), respectively. For every 1 mcg/dL cortisol increase after overnight dexamethasone, visceral fat/muscle area ratio increased by 2.3 (P=0.02) and mean total skeletal muscle area decreased by 2.2cm2 (P=0.03). Conclusion: Patients with adrenal adenomas demonstrate a lower muscle mass and a higher proportion of visceral fat when compared to referent subjects, including patients with NFAT. Even a subtle abnormality in cortisol secretion may impact health of patients with adenomas.


2021 ◽  
Vol 6 (3) ◽  
pp. 413-421
Author(s):  
Sapna Yadav ◽  
Gaurav Kadyan

Background: This study aimed to compare and correlate the resting heart rate, body composition and heart rate variability among judo and wushu players. Method: 40 athletes (20 judo and 20 wushu players) were included in the study. Body composition (BMI, subcutaneous body mass, skeletal body mass, body fat %, body density, Visceral fat, Lean body mass) was evaluated with the help of 7 skinfold thickness and body circumferences with the help of Harpenden calliper and measuring tape respectively. HRV (RMSSD, SDNN, LF/HF, LFnu and HFnu) was recorded in resting state (~5min) with the help of Heart wear shimmer ECG device. Result: No significant difference of body composition and HRV variables (p> 0.05) was found between the two groups except Body fat % and body density (p<0.05) which differ significantly among the two groups. In Judo, LF/HF and LFnu showed significant positive correlation with BMI (p<0.05, r=-0.488), subcutaneous whole-body mass (p<0.05, r=-0.464), visceral fat (p<0.05, r =-0.508), and body fat % (p<0.05, r =-0.626. Whereas HFnu showed significant negative correlation with BMI (p<0.05, r=-0.488), subcutaneous whole-body mass (p<0.05, r=-0.464), visceral fat (p<0.05, r=-0.505) and body fat % (p<0.05, r=-0.626). Whereas no correlation was found between HRV and Body composition in wushu players. Conclusion: Reduction in body fat % and visceral fat in judo players indicate improved sympathovagal balance which can be due to the adaptation induced by training loads. Similar results were not seen in wushu players because of high amount of body fat% and visceral fat. Keywords: Body composition, combat sports, heart rate variability, Body fat %, resting heart rate.


Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Alexis Jones ◽  
Jacob L Barber ◽  
James S Skinner ◽  
Claude Bouchard ◽  
Mark A Sarzynski

Background: Body composition is known to differ across metabolic health and weight phenotypes. Regular exercise improves body composition, yet little is known about differences in exercise response across metabolic health and weight phenotypes. Methods: Normal weight (n=376) and overweight/obese (OWOB) adults (n=456) from the HERITAGE Family Study (56% female, 38% Black) completed a 20-week endurance training program. Four groups based on baseline BMI and metabolic risk were created: metabolically healthy normal weight, MHNW; metabolically unhealthy normal weight, MUNW; metabolically healthy OWOB, MHO; and metabolically unhealthy OWOB, MUO. Unhealthy was defined as having ≥2 metabolic syndrome components. General linear models tested for differences in baseline and change in measures of body composition (fat mass [FM], fat-free mass [FFM], % body fat [%BF], visceral fat) after adjusting for age, sex, and ethnicity (and baseline value in change models). Results: Table 1 shows adjusted mean baseline and change in body composition values by group. Baseline body composition tended to track with weight status, with NW adults having lower FM, %BF, and visceral fat compared to obese adults (p<0.05), regardless of metabolic health. However, the MHO group had lower baseline values of these traits compared to MUO (p<0.05). Body composition measures significantly improved with exercise training in all groups, however, the magnitude of change differed between groups. For example, both NW groups had larger decreases in %BF compared to the obese groups, with MUNW showing the largest decrease. Conversely, MHNW showed the largest decrease in visceral fat, which was greater than both obese groups, but change in visceral fat was similar between MHO and MUNW. Conclusions: Normal weight adults tended to have better body composition profiles at baseline and larger improvements with exercise compared to obese adults, regardless of metabolic health. Within weight groups, body composition improved regardless of metabolic health status.


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