Experimental studies in insect parasitism XIV. The haemocytic reaction of a caterpillar to larvae of its habitual parasite

1966 ◽  
Vol 165 (999) ◽  
pp. 155-178 ◽  
Keyword(s):  
Foreign Body ◽  
Embryonic Development ◽  
Chemical Treatment ◽  
Blood Cells ◽  
Protective Property ◽  
Foreign Bodies ◽  
Experimental Studies ◽  
Ephestia Kuehniella ◽  
Main Theme ◽  
Ionic Exchange

Although caterpillars of Ephestia kuehniella promptly encapsulate alien parasites and other foreign bodies in their haemocoele, they do not normally encapsulate larvae of their habitual parasite Nemeritis canescens , which develop unhindered and eventually destroy their host. The larva of Nemeritis does not achieve this immunity by repelling the blood cells, or by physically dislodging them. It is immune because it is able to live in the haemocoele of Ephestia without evoking a haemocytic reaction; presumably, that is, because it is not recognized as a foreign body. That ability is due to a property of its surface. So long as its surface remains unaltered, the larva, alive or dead, evokes no haemocytic reaction. When its surface is altered whether by perforation, abrasion, or chemical treatment, the living larva evokes a haemocytic reaction in Ephestia and becomes encapsulated. The protective property of its surface is acquired by the larva very late in its embryonic development, between 62 and 66 hours of age at 25 °C. This is about the same time as, or a little later than, the cuticle of the embryonic larva becomes impermeable to water. Four fat solvents were found to deprive the living larva of its immunity, but they may have affected the protective surface by disrupting the underlying wax layer of the epicuticle. Treatments and substances that did not affect the protective surface give some crude indications of its properties, but its ultimate characterization must be in terms of insect immunology. Observations incidental to the main theme of the paper show that the cuticle of the larva is impermeable to water; that ionic exchange takes place through the anus and wall of the rectum, where some food substances may also be absorbed from the blood of the host; and that the order of formation of the cuticulin and wax layers of the embryonic larva is the same as that in ecdysis from instar to instar in other insects. They also provide information on the longevity of bitten supernumerary larvae.

Experimental studies in insect parasitism XIII. The haemocytic reaction of a caterpillar to eggs of its habitual parasite

1965 ◽  
Vol 162 (988) ◽  
pp. 303-318 ◽  
Keyword(s):  
Outer Surface ◽  
Blood Cells ◽  
Genital Tract ◽  
Distal Part ◽  
Experimental Studies ◽  
Ephestia Kuehniella ◽  
Adult Parasite ◽  
Living Tissues ◽  
By Products

Caterpillars of Ephestia kuehniella promptly encapsulate alien parasites, living tissues from other species of insects, and filaments of such inert substances as Polythene and Polyfluorocarbon implanted in their haemocoele. They do not encapsulate eggs of their habitual parasite Nemeritis canescens , and the paper records an investigation of that failure. Eggs of Nemeritis do not repel the haemocytes or prevent them from forming capsule tissue; they escape encapsulation because they do not stimulate the blood cells to react. The property that enables them to avoid evoking a reaction is located on their surface: dead eggs that retained an unaltered surface were not encapsulated, living or dead eggs of which the surface was experimentally altered were encapsulated. Since eggs of Nemeritis possess this protective surface immediately after oviposition, its origin was sought in the adult parasite . The surface of eggs removed from the distal part of the ovarioles is formed by the chorion; eggs removed from the genital tract below the calyx were found to have a visible layer outside the chorion. When eggs bearing this visible layer were removed from several parts of the genital tract and injected into caterpillars of Ephestia , they were not encapsulated. When eggs not bearing the visible layer outside the chorion were removed from ovarioles, and were injected into caterpillars, they always evoked a haemocytic reaction and were usually completely encapsulated. The property of its surface that enables the egg of Nemeritis to avoid evoking a haemocytic reaction in Ephestia is therefore acquired in the region of the calyx, where also the visible layer appears on the outer surface of the chorion. A few by-products of the investigation are mentioned in the discussion.

Experimental studies in insect parasitism. XVI. The mechanism of the resistance of Nemeritis to defence reactions

1973 ◽  
Vol 183 (1073) ◽  
pp. 337-350 ◽  
Keyword(s):  
Cell Adhesion ◽  
Blood Cells ◽  
Mode Of Action ◽  
Direct Action ◽  
Experimental Studies ◽  
Tenebrio Molitor ◽  
Ephestia Kuehniella ◽  
Achroia Grisella ◽  
Internal Lining ◽  
Defence Reactions

The egg of the ichneumon wasp Nemeritis canescens is known to be resistant to the defence reactions of its usual host, Ephestia kuehniella , by virtue of a coating on its surface. The coating is here shown also to endow Nemeritis with resistance to the defence reactions of Achroia grisella and, by implication, several other species of hosts. Three ways in which the coating might act are: (1) passively, by mimicking the lining of the haemocoele; (2) indirectly, by preventing the modification of substances in the haemolymph; (3) directly, by inhibiting the adhesion of blood cells. Mimicry of the host’s internal lining is ruled out by experiments showing that the blood cells of Ephestia react to the internal lining of Achroia , and vice versa, although neither host reacts to Nemeritis . The idea that the coating might prevent modification of substances in the plasma, and so indirectly inhibit encapsulation, is not completely eliminated; but several experiments provide no evidence for it, and several observations favour a hypothesis of direct action by the particles on the blood cells. The nature of that direct action is inconclusively examined. Preliminary experiments suggest that the particles dissociate the cells of young capsules of Ephestia and may, therefore, act to inhibit the adhesion of cells to form capsules. Cells of capsules formed in Tenebrio molitor , which always encapsulates Nemeritis , were not dissociated; which indicates that this mode of action has the required element of specificity. The possibility that substances chemically similar to the particles of Nemeritis might inhibit cell adhesion and aggregation in vertebrates is briefly discussed.

A Large Bullet in the Bladder

Swiss Surgery ◽  
2001 ◽  
Vol 7 (3) ◽  
pp. 139-140 ◽  
Author(s):  
Halkic ◽  
Wisard ◽  
Abdelmoumene ◽  
Vuilleumier
Keyword(s):  
Foreign Body ◽  
Foreign Bodies ◽  
Gross Hematuria ◽  
Suprapubic Cystostomy ◽  
Laparoscopic Port ◽  
Urethral Trauma ◽  
Bullet Injury

All manner of foreign bodies have been extracted from the bladder. Introduction into the bladder may be through self-insertion, iatrogenic means or migration from adjacent organs. Extraction should be tailored according to the nature of the foreign body and should minimise bladder and urethral trauma. We report a case of a bullet injury to the bladder, which finally presented as a gross hematuria after remaining asymptomatic for four years. We present here an alternative to suprapubic cystostomy with a large bladder foreign body treated via a combined transurethral unroofing followed by removal using a grasper passed through a suprapubic laparoscopic port.

CLINICAL AND PARACLINICAL CHARACTERISTICS AND RESULTS FROM TREATMENT OF FOREIGN BODIES INGESTION

2016 ◽  
pp. 63-69
Author(s):  
Hoang Cuong Vo ◽  
Thanh Dang ◽  
Phuong Nam Tran ◽  
Thanh Thai Le
Keyword(s):  
Foreign Body ◽  
Clinical Characteristics ◽  
Foreign Bodies ◽  
University Hospital ◽  
Age Group ◽  
Central Hospital ◽  
Results Of Treatment ◽  
Rigid Esophagoscopy ◽  
Flexible Esophagoscopy ◽  
Esophageal Foreign Bodies

Background: Foreign bodies ingestion is a emergency in otology, knowledge of people about foreign bodies ingestion is not enough. Objective: To study the clinical characteristics, paraclinical characteristics and results of treatment from foreign bodies ingestion in Hue Central Hospital and Hue University Hospital. Methods and patiens: A cross descriptive and prospective study over the period from 6/2014 to 5/2016, total are 137 patients come to be diagnosised and treatmented. Results: the average age is 35 years old. Gender: male (51.8%) and women (48.2%). Adults (84.7%) having more than children (15.3%). Age group from 16-30 years is highest (32.8%). There are 95.7% of organic foreign bodies, 4.3% are inorganic foreign bodies. There are 90.5% of patients on diagnosis and treatment in stages less inflammation, arthritis 8.0% in the period and 1.5% in the period complications. Foreign body in the throat problems (73.7%), esophageal foreign bodies (26.3%). Pick up directly foreign bodies 54%, indirectly by the mirror 11.7% and endoscopy 8%, rigid esophagoscopy is 17.5%, flexible esophagoscopy is 7.3%, cervicotomy is 1.5%. Conclusion: Practing direction with in the oropharynx foreign body, using the larynx mirror or endoscopy with in the laryngopharynx for the esophagus foreign bodies, rigid esophagoscopy is better. Key words: Foreign bodies ingestion

scholarly journals Emerging cellular and molecular mechanisms underlying anticancer indications of chrysin

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Marjan Talebi ◽  
Mohsen Talebi ◽  
Tahereh Farkhondeh ◽  
Jesus Simal-Gandara ◽  
Dalia M. Kopustinskiene ◽  
...  
Keyword(s):  
Blood Cells ◽  
Molecular Mechanisms ◽  
Web Of Science ◽  
Experimental Studies ◽  
Protective Effects ◽  
Pharmacological Activities ◽  
Current Review ◽  
Mesh Terms ◽  
Online Databases ◽  
Anti Cancer

AbstractChrysin has been shown to exert several beneficial pharmacological activities. Chrysin has anti-cancer, anti-viral, anti-diabetic, neuroprotective, cardioprotective, hepatoprotective, and renoprotective as well as gastrointestinal, respiratory, reproductive, ocular, and skin protective effects through modulating signaling pathway involved in apoptosis, oxidative stress, and inflammation. In the current review, we discussed the emerging cellular and molecular mechanisms underlying therapeutic indications of chrysin in various cancers. Online databases comprising Scopus, PubMed, Embase, ProQuest, Science Direct, Web of Science, and the search engine Google Scholar were searched for available and eligible research articles. The search was conducted by using MeSH terms and keywords in title, abstract, and keywords. In conclusion, experimental studies indicated that chrysin could ameliorate cancers of the breast, gastrointestinal tract, liver and hepatocytes, bladder, male and female reproductive systems, choroid, respiratory tract, thyroid, skin, eye, brain, blood cells, leukemia, osteoblast, and lymph. However, more studies are needed to enhance the bioavailability of chrysin and evaluate this agent in clinical trial studies. Graphic abstract

How we do it: impacted oesophageal foreign body removal using a dilatation balloon

2021 ◽  
pp. 1-3
Author(s):  
P D Chakravarty ◽  
T Kunanandam ◽  
G Walker
Keyword(s):  
Foreign Body ◽  
Granulation Tissue ◽  
Foreign Bodies ◽  
Fluoroscopic Guidance ◽  
Tertiary Referral ◽  
Foreign Body Removal ◽  
Novel Technique ◽  
Common Presentation ◽  
Reproducible Technique ◽  
Rigid Oesophagoscopy

Abstract Background Ingested foreign bodies are a common presentation to paediatric ENT services. Depending on the site, these are usually managed with flexible or rigid oesophagoscopy and retrieval. This paper presents a novel technique for removing a hollow foreign body that could not be removed using conventional means. Method and results After rigid and flexible approaches failed, a guidewire was passed through the foreign body under fluoroscopic guidance and a dilatation balloon passed through the lumen of the object. Inflating the balloon allowed dilatation of the inflamed mucosa above and below the object, facilitating straightforward removal under traction. Conclusion This is a novel and reproducible technique that uses equipment readily available in tertiary referral centres. Employed in this context, the technique enabled removal of an impacted object surrounded by granulation tissue, and would be appropriate for other objects with a lumen.

Use of Ophthalmic Sonography to Evaluate for Intraocular Foreign Body in Both Outpatient and Emergency Department/Urgent Care Patients

2021 ◽  
pp. 875647932110332
Author(s):  
Patrick J. Fish
Keyword(s):  
Emergency Department ◽  
Foreign Body ◽  
Foreign Bodies ◽  
Outpatient Setting ◽  
Intraocular Foreign Body ◽  
Urgent Care ◽  
Posterior Chamber ◽  
Emergency Department Setting ◽  
Before And After ◽  
Glass Metal

Intraocular foreign bodies (IOFB) present differently depending on the type of material (wood, glass, metal) for the IOFB, extent of the injury, and location of the injury. IOFB and the injury can cause a perforation or penetration of the globe which can require more extensive treatment including surgery. Proper evaluation of the IOFB and injury can help to determine extent of the injury, the prognosis of the vision, and health of the eye before and after treatment but may be difficult for the physician depending on the view of the posterior chamber being compromised by media or simply by patient sensitivity. The extent of the injury may also prevent proper evaluation due to swelling, lacerations on the lids, or pain. Proper ophthalmic sonography can provide a quick evaluation of the globe for any IOFB in both the outpatient setting as well as emergency department setting. Evaluation via sonography may allow the physician to accurately diagnose and properly treat the patient to help restore and prevent further loss of vision.

scholarly journals Challenges in Management of Tracheobronchial Foreign Bodies with Delayed Presentation: An Institutional Experience

2021 ◽  
Author(s):  
Darwin Kaushal ◽  
Amit Goyal ◽  
Kapil Soni ◽  
Bikram Choudhury ◽  
Nithin Prakasan Nair ◽  
...  
Keyword(s):  
Foreign Body ◽  
Foreign Bodies ◽  
Preoperative Planning ◽  
Rigid Bronchoscopy ◽  
Delayed Presentation ◽  
Betel Nut ◽  
Key Factors ◽  
Tracheobronchial Foreign Body ◽  
Institutional Experience ◽  
Definitive Management

Abstract Introduction Airway foreign bodies are emergencies involving multidisciplinary departments like Pediatrics, Aneasthesiology and Otorhinolaryngology. It is always a challenge to diagnose and manage patients who present late to our emergencies. Objective In the present study, we aim to analyze the various challenges faced during the management of tracheobronchial foreign bodies with delayed presentation. Methods A retrospective hospital record-based analysis of patients who presented to us with tracheobronchial foreign bodies from January 2017 to February 2020 was performed. All patients until the age of 16 years old were included in the present study. We assessed the demographics, preoperative, intraoperative and postoperative data of the patients. Results Seventeen patients were analyzed in the study. Among these, 44.4% of the patients had delayed presentation (> 1 month). The majority of the patients had an organic foreign body (Supari or betel nut). All patients underwent rigid bronchoscopy, followed by optical forceps-assisted removal of the foreign body. A total of 82% of the patients had granulations around the foreign body. Conclusion Management of delayed presentation tracheobronchial foreign body is a big challenge for Otorhinolaryngologists. The key factors for preventing complications in the definitive management of tracheobronchial foreign bodies are preoperative planning, multi-discipline teamwork, surgeon expertise and technique.

scholarly journals Intruding implements: a pictorial review of retained surgical foreign objects in neuroradiology

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Alessandra D’Amico ◽  
Teresa Perillo ◽  
Lorenzo Ugga ◽  
Renato Cuocolo ◽  
Arturo Brunetti
Keyword(s):  
Differential Diagnosis ◽  
Foreign Body ◽  
Foreign Bodies ◽  
Correct Identification ◽  
Pathophysiological Mechanism ◽  
Local Inflammatory Response ◽  
Inflammatory Reactions ◽  
Foreign Objects ◽  
Pictorial Review ◽  
Review Reports

AbstractIntra-cranial and spinal foreign body reactions represent potential complications of medical procedures. Their diagnosis may be challenging as they frequently show an insidious clinical presentation and can mimic other life-threatening conditions. Their pathophysiological mechanism is represented by a local inflammatory response due to retained or migrated surgical elements. Cranial interventions may be responsible for the presence of retained foreign objects represented by surgical materials (such as sponges, bone wax, and Teflon). Spinal diagnostic and therapeutic procedures, including myelography, chordotomy, vertebroplasty, and device implantation, are another potential source of foreign bodies. These reactions can also follow material migration or embolization, for example in the case of Lipiodol, Teflon, and cement vertebroplasty. Imaging exams, especially CT and MRI, have a central role in the differential diagnosis of these conditions together with patient history. Neuroradiological findings are dependent on the type of material that has been left in or migrated from the surgical area. Knowledge of these entities is relevant for clinical practice as the correct identification of foreign bodies and related inflammatory reactions, material embolisms, or migrations can be difficult. This pictorial review reports neuroradiological semeiotics and differential diagnosis of foreign body-related imaging abnormalities in the brain and spine.

scholarly journals Unique Pattern of True Foreign-Body Ingestion in the Valley of Kashmir; Sharp Foreign Bodies Outnumbering the Blunt Ones

2019 ◽  
Vol 10 (01) ◽  
pp. 028-032
Author(s):  
Nisar Ahmad Shah ◽  
Showkat Ahmad Kadla ◽  
Asif Iqbal Shah ◽  
Bilal Ahmad Khan ◽  
Inaam Ul Haq ◽  
...  
Keyword(s):  
Foreign Body ◽  
Success Rate ◽  
Foreign Bodies ◽  
Foreign Body Ingestion ◽  
Young Females ◽  
The People ◽  
Early Endoscopy ◽  
Normal Individuals ◽  
Structural Abnormalities ◽  
The Impact

ABSTRACT Background and Aims: Foreign-body ingestion is a common phenomenon, especially in children. In normal adults, foreign-body ingestion is usually accidental and mostly ingestion occurs with food and impaction is a result of structural abnormalities of the upper gastrointestinal tract (UGIT). However, accidental ingestion of nonfood products is unusual; especially ingestion of pins (scarf or safety pins) and needles is unknown. We come across ingestion of these unusual/sharp foreign bodies routinely from the past few years. The aim of this study was to observe, over a period of 1 year, the spectrum of nonfood or true foreign-body ingestion in our community and to see the impact of an early endoscopy on outcome or retrieval of the ingested objects. Materials and Methods: In a prospective observational study, we studied the profile of foreign-body ingestion in normal individuals of all ages and both sexes, excluding the individuals with any structural abnormalities of the gut and the people with psychiatric ailment. Results: Of total 51 patients with foreign-body ingestion, 42 (82%) were 20 or <20 years of age with females constituting 86.3% of the total and males constituting only 13.7%. Foreign bodies ingested included 38 pins (74.5%), seven coins (13.7%), four needles (7.8%), and one denture and a nail (2%) each. Overall 26 (51%) foreign bodies were seen in UGIT (within reach of retrieval) at the time of endoscopy and all of them were retrieved. Nineteen (37.3%) patients reported within 6 h of ingestion, and majority of them (16 = 84.2%) had foreign bodies within UGIT and all of them were removed. Those patients (n = 32; 62.7%) who reported beyond 6 h, only 10 (31.25%) had foreign bodies in UGIT as a result of which the success rate of removal in these patients was only 32%. Conclusion: Most of our patients were young females and the common foreign bodies ingested were sharp including scarf pins followed by coins and needles. The success rate of retrieval was high in those who reported within 6 h of ingestion of foreign body. The rate of retrieval was 100% if foreign body was found on esophagogastroduodenoscopy. Hence, we recommend an early endoscopy in these patients and some alternative to use of scarf pins.

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