scholarly journals High degree of genetic diversity of non-polio enteroviruses identified in Georgia by environmental and clinical surveillance, 2002–2005

2010 ◽  
Vol 59 (11) ◽  
pp. 1340-1347 ◽  
Author(s):  
N. Khetsuriani ◽  
T. Kutateladze ◽  
E. Zangaladze ◽  
T. Shutkova ◽  
S. Peñaranda ◽  
...  
Keyword(s):  
Large Scale ◽  
Added Value ◽  
Genetic Lineage ◽  
Genetic Lineages ◽  
Geographical Patterns ◽  
Clinical Surveillance ◽  
The Usa ◽  
Stool Samples ◽  
High Degree

Enterovirus surveillance data are useful for establishing temporal and geographical patterns of circulation and for virus characterization to determine phylogenetic relationships between strains. Almost no information is available on circulating enteroviruses in Georgia and the surrounding region. To describe enterovirus circulation in Georgia, determine relationships with previously characterized strains and assess the role of environmental and clinical enterovirus surveillance, this study analysed a total of 112 non-polio enterovirus isolates identified during 2002–2005 from sewage and human stool samples. Viruses were isolated in cell culture using standard methods and typed by partial sequencing of the VP1 gene. A total of 20 different non-polio enterovirus serotypes were identified over the 4-year period. The most commonly detected enteroviruses included echovirus (E) 6 (21 isolates; 18.8 %), E20, E3 and E7 (11 isolates each; 9.8 %), E11, coxsackievirus (CV) B4 and CVB5 (seven isolates each; 6.3 %), and E13, E19 and E30 (six isolates each; 5.4 %). Phylogenetic analysis showed that many serotypes were represented by more than one genetic lineage. The present study showed a very high degree of enterovirus diversity in Georgia and demonstrated the added value of environmental enterovirus surveillance, particularly in settings with limited clinical surveillance. Several serotypes would not have been detected without having both clinical and environmental surveillance in place. Several serotypes detected in Georgia were among those rarely reported in the USA and Europe (e.g. E3, E20 and E19). As the emergence of new genetic lineages of enterovirus in a particular area is often associated with large-scale outbreaks, continued monitoring of enterovirus strains by both environmental and clinical surveillance and genetic characterization should be encouraged.

The academic profession in Russia’s two capitals: The impact of 20 years of transition

2017 ◽  
Vol 16 (5) ◽  
pp. 626-644 ◽  
Author(s):  
Elizaveta Sivak ◽  
Maria Yudkevich
Keyword(s):  
Large Scale ◽  
Academic Career ◽  
Academic Profession ◽  
University Faculty ◽  
Key Characteristics ◽  
Personal Strain ◽  
High Degree ◽  
The Impact ◽  
Russian Universities

This paper studies the dynamics of key characteristics of the academic profession in Russia based on the analysis of university faculty in the two largest cities in Russia – Moscow and St Petersburg. We use data on Russian university faculty from two large-scale comparative studies of the academic profession (‘The Carnegie Study’ carried out in 1992 in 14 countries, including Russia, and ‘The Changing Academic Profession Study’, 2007–2012, with 19 participating countries and which Russia joined in 2012) to look at how faculty’s characteristics and attitudes toward different aspects of their academic life changed over 20 years (1992–2011) such as faculty’s views on reasons to leave or to stay at a university, on university’s management and the role of faculty in decision making. Using the example of universities in the two largest Russian cities, we demonstrate that the high degree of overall centralization of governance in Russian universities barely changed in 20 years. Our paper provides comparisons of teaching/research preferences and views on statements concerning personal strain associated with work, academic career perspectives, etc., not only in Russian universities between the years 1992 and 2012, but also in Russia and other ‘Changing Academic Profession’ countries.

Events in Northern Africa and Middle East: Causes and Consequences

2011 ◽  
pp. 11-25
Author(s):  
I. Labinskaya
Keyword(s):  
Middle East ◽  
North Africa ◽  
Large Scale ◽  
Arab Countries ◽  
Northern Africa ◽  
External Factors ◽  
Wide Range ◽  
The Usa ◽  
Oriental Studies

Political developments in North Africa and the Middle East that have begun in January 2011 are gaining strength and involve an increasing number of Arab countries. The participants of the Roundtable – experts from IMEMO, Institute of Oriental Studies (RAS), Institute of the USA and Canada (RAS) and Mrs. E. Suponina from “Moscow News” newspaper analyzed a wide range of issues associated with these events. Among them are: 1) the reasons for such a large-scale explosion, 2) the nature of the discussed developments (revolutions, riots?) and who are the subjects of the current “Arab drama”, 3) the role of Islam and political Islamism, 4) the role of external factors.

scholarly journals Psychological conditions for the prevention of recidivism

2020 ◽  
Vol 9 (1) ◽  
pp. 85-93
Author(s):  
A.V. Sechko
Keyword(s):  
Driving Forces ◽  
Delinquent Behavior ◽  
Stress Factors ◽  
Criminal Prosecution ◽  
Economic Problems ◽  
Psychological Conditions ◽  
The Usa ◽  
Time Parameters ◽  
High Degree

The article analyzes the results of a study of recidivism conducted in England, Denmark, Canada, Nigeria, Portugal, New Zealand, the USA, and Scotland. Objective and subjective determinants have been identified that make it possible to predict with a high degree of probability the subsequent criminal prosecution violation, its time parameters. The psychological portrait of the recidivist is described, stress factors of delinquent behavior are revealed. The driving forces of decriminalization of former criminals are revealed. This is an intensive probationary period under the auspices of mentors who are able to build trusting relationships with parole through consistent, non-judgmental actions with the simultaneous possibility of playing the role of guardians of young people in difficult social and criminal settings in solving their economic problems.

A Past to Present Journey

2015 ◽  
pp. 180-206
Author(s):  
Moyassar Al-Taie ◽  
Michael Lane ◽  
Aileen Cater-Steel
Keyword(s):  
Large Scale ◽  
Chief Information Officer ◽  
Supply Side ◽  
Demand Side ◽  
It Infrastructure ◽  
The Usa ◽  
Large Scale Survey ◽  
Infrastructure Services ◽  
Skilled Staff

This chapter explores the role of the Chief Information Officer (CIO). A detailed review of the existing literature traces the evolution of this role and highlights its characteristics and configurations. CIO role effectiveness can be described in terms of three demand-side roles: strategist, relationship architect, integrator, and three supply-side roles: educator, information steward, and utility provider. To explore the configuration of roles of CIOs in Australia, a large-scale survey of CIOs was conducted. The Australian results, based on 174 responses, are compared with those from similar studies in USA. The top priority for the Australian CIO was information steward, ensuring organizational data quality and security and recruiting and retaining IT skilled staff. In comparison, the first priority for the USA CIOs was utility provider - building and sustaining solid, dependable, and responsive IT infrastructure services. This study's findings have implications for CIO career development and recruitment.

Modeling large dust deposition events to alpine snow and their impacts: the role of model resolution

2021 ◽  
Author(s):  
Foteini Baladima ◽  
Jennie Thomas ◽  
Marie Dumont ◽  
Didier Voisin ◽  
Clementine Junquas ◽  
...  
Keyword(s):  
High Resolution ◽  
Large Scale ◽  
Horizontal Resolution ◽  
Added Value ◽  
Model Resolution ◽  
Dust Deposition ◽  
Mountain Regions ◽  
Mountain Meteorology ◽  
The Alps

<div>Mineral dust and black carbon (BC) constitute the most important aerosols present in the atmosphere and cryosphere and have well known potential effects on regional and global climate. Upon their deposition they can impact snow albedo, snowpack evolution and timing of snow-melt. However, capturing BC and dust deposition events in mountain regions is currently a challenge due to the complexity of aerosol-cloud interactions and the specifics of mountain meteorological systems, which are difficult to represent in large scale models. Here, we use a case study of dust deposition, between 30 March and 5 April 2018, when a significant dust deposition event was observed within the seasonal snowpack at the Col du Lautaret in the French Alps. This comes in addition to the background BC deposition that occurred during the same period. Specifically, we investigate the role of model resolution in capturing both mountain meteorology, precipitation, and the resulting model predicted dust and BC deposition. For this, the meteorological-chemical model WRF-Chem is used with three nested domains including the primary dust emissions region in Africa (low resolution domain), a second domain that includes Europe, and a third high resolution domain over the Alps. We compare WRF-Chem predicted aerosol and meteorological properties (at different model resolution) with in-situ, remote sensing, and reanalysis products to validate the model and quantify the added value of high resolution modelling within the Alps. We conclude that predicted mountain meteorology including precipitation is significantly better when using the high resolution configuration (3 x 3 km horizontal resolution domain). Additionally, this improved meteorology predicted by the model has significant impacts on predicted dust deposition and BC. The better representation of the mountain meteorology when the resolution becomes finer leads to improved model predicted dust and BC deposition to alpine snow. Implications for this, including improved resolution within models that consider the full aerosol lifecycle in the atmosphere and in snow covered mountain regions is discussed.</div>

scholarly journals A Strategic Vision to Reduce Cybercrime to Enhance Cyber Security

Webology ◽  
2020 ◽  
Vol 17 (2) ◽  
pp. 289-295
Author(s):  
Mohammed I. Alghamdi
Keyword(s):  
Saudi Arabia ◽  
Cyber Security ◽  
Human Security ◽  
Community Members ◽  
Cyber Terrorism ◽  
Strategic Vision ◽  
The Usa ◽  
Cyber Crimes ◽  
High Degree

The cyber-security development for future generations is at stake as a global concern. The existing strategic and policy structures on cyber security and awareness-raising at many levels needs more investigation in order to formulate workable and efficient strategic vision that addresses actual needs and challenges. The justification for this work is therefore to test the robustness, in contrast with some of the most technologically advanced countries on the Asian Continent and others like the USA, Japan, of Saudi Arabia's current cyber security strategy in order to keep the NCSS up-to-date. This research aimed to develop a strategic vision to combat cybercrime to enhance cyber security. The research results confirmed the approval of the members of the study community to a medium degree on the reality of digital extremism and cyber terrorism as seen by the researcher. Moreover, the approval of the members of the study community was to a high degree on the role of combating cybercrime in promoting human security as seen by the researcher. The members of the study community agreed with a high degree on the obstacles identified by the researcher to combat cyber-crimes to enhance human security in Saudi Arabia. There was a high approval of the study community members on the strategic vision developed by the researcher to combat cyber-crimes to enhance human security in Saudi Arabia.

scholarly journals The role of ethnicity in psychopharmacology

2007 ◽  
Vol 4 (3) ◽  
pp. 55-56 ◽  
Author(s):  
Pedro Ruiz
Keyword(s):  
Large Scale ◽  
Minority Groups ◽  
Second World War ◽  
World War ◽  
The Usa ◽  
The Relationship ◽  
Second World ◽  
Psychopharmacological Agents ◽  
Migrant Groups

The association between ethnicity and pharmacology has been reported in the medical literature for several decades. However, the relationship between ethnicity and psychopharmacology has become widely recognised only in the last two or three decades. The large-scale migration which started after the Second World War, at first to the USA and more recently to other higher-income countries, as a result of globalisation, has greatly contributed to the attention and focus given to these migrant groups. In this context, these migrant groups primarily comprise ethnic and racial minority groups. This article briefly reviews the relationship between ethnicity and psychopharmacological agents.

scholarly journals War in Afghanistan: Europe and America, between Films and Documentaries. 1979-2014

2017 ◽  
Vol 9 (1) ◽  
pp. 26
Author(s):  
Jose Mauricio Saldanha-Alvarez
Keyword(s):  
North Atlantic ◽  
Large Scale ◽  
Afghanistan War ◽  
American Cinema ◽  
Media System ◽  
Informative Role ◽  
The Usa ◽  
Soviet Invasion ◽  
Real Action

This research looks at the Afghanistan War from the Soviet invasion of 1979 until the withdrawal of North Atlantic Treaty Organization in 2014 through films chosen. This research demonstrates how the Soviets, supported by the USA and the Muslim world, operated on misconceptions during an insurrectional conflict against the Mujahedin. After September 11, the Bush-Cheney administration invaded Afghanistan, restricting the informative role of the corporate media system. According to Kellner, this action triggered a creative revolution in American cinema. Turning to the production of documentaries, directors abandoned large-scale productions, preferring highly dramatically charged narratives of real soldiers and real action. The Afghan war, a fragmented, relentless, and unremitting struggle, is portrayed in 9th Company (Rus), Restrepo (USA). And Armadillo (Denmark); and Kajaki (UK), films that narrates the conflict from the NATO perspective, can not be won.

scholarly journals The Evolving Role of Next-Generation Sequencing in Screening and Diagnosis of Hemoglobinopathies

2021 ◽  
Vol 12 ◽  
Author(s):  
Ahlem Achour ◽  
Tamara T. Koopmann ◽  
Frank Baas ◽  
Cornelis L. Harteveld
Keyword(s):  
Next Generation Sequencing ◽  
Large Scale ◽  
Genetic Diseases ◽  
Molecular Techniques ◽  
Added Value ◽  
Monogenic Disease ◽  
Clinical Genetics ◽  
Next Generation ◽  
Generation Sequencing

During the last few years, next-generation sequencing (NGS) has undergone a rapid transition from a research setting to a clinical application, becoming the method of choice in many clinical genetics laboratories for the detection of disease-causing variants in a variety of genetic diseases involving multiple genes. The hemoglobinopathies are the most frequently found Mendelian inherited monogenic disease worldwide and are composed of a complex group of disorders frequently involving the inheritance of more than one abnormal gene. This review aims to present the role of NGS in both screening and pre- and post-natal diagnostics of the hemoglobinopathies, and the added value of NGS is discussed based on the results described in the literature. Overall, NGS has an added value in large-scale high throughput carrier screening and in the complex cases for which common molecular techniques have some inadequacies. It is proven that the majority of thalassemia cases and Hb variants can be diagnosed using routine analysis involving a combined approach of hematology, hemoglobin separation, and classical DNA methods; however, we conclude that NGS can be a useful addition to the existing methods in the diagnosis of these disorders.

scholarly journals Large-scale distribution of hybridogenetic lineages in a Spanish desert ant

2014 ◽  
Vol 281 (1774) ◽  
pp. 20132396 ◽  
Author(s):  
Hugo Darras ◽  
Laurianne Leniaud ◽  
Serge Aron
Keyword(s):  
Large Scale ◽  
Genetic Lineage ◽  
Unique Case ◽  
Genetic Lineages ◽  
Long Period ◽  
Desert Ant ◽  
Evolutionarily Conserved ◽  
Geographical Scale ◽  
Males And Females ◽  
Social Level

Recently, a unique case of hybridogenesis at a social level was reported in local populations of the desert ants Cataglyphis . Queens mate with males originating from a different genetic lineage than their own to produce hybrid workers, but they use parthenogenesis for the production of reproductive offspring (males and females). As a result, non-reproductive workers are all inter-lineage hybrids, whereas the sexual line is purely maternal. Here, we show that this unorthodox reproductive system occurs in all populations of the ant Cataglyphis hispanica . Remarkably, workers are hybrids of the same two genetic lineages along a 400 km transect crossing the whole distribution range of the species. These results indicate that social hybridogenesis in C. hispanica allows their maintenance over time and across a large geographical scale of two highly divergent genetic lineages, despite their constant hybridization. The widespread distribution of social hybridogenesis in C. hispanica supports that this reproductive strategy has been evolutionarily conserved over a long period.

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