scholarly journals Individual differences in functional connectivity during naturalistic viewing conditions

2016 ◽  
Author(s):  
Tamara Vanderwal ◽  
Jeffrey Eilbott ◽  
Emily S. Finn ◽  
R. Cameron Craddock ◽  
Adam Turnbull ◽  
...  

AbstractNaturalistic viewing paradigms such as movies have been shown to reduce participant head motion and improve arousal during fMRI scanning relative to task-free rest, and have been used to study both functional connectivity and task-evoked BOLD-signal changes. These task-evoked changes result in cortical activity that is synchronized across subjects and involves large areas of the cortex, and it is unclear whether individual differences in functional connectivity are enhanced or diminished under such naturalistic conditions. This work first aims to characterize variability in functional connectivity (FC) across two distinct movie conditions and eyes-open rest (n=34 healthy adults, 2 scan sessions each). At the whole-brain level, we found that movies have higher intra- and inter-subject correlations in cluster-wise FC relative to rest. The anatomical distribution of inter-subject variability was similar across conditions, with higher variability occurring at the lateral prefrontal lobes and temporoparietal junctions. Second, we used an unsupervised test-retest matching (or “finger-printin”) algorithm that identifies individual subjects from within a group based on functional connectivity patterns, quantifying the accuracy of the algorithm across the three conditions. We also evaluated the impact of parcellation resolution, scan duration, and number of edges on observed inter-individual differences. The movies and resting state all enabled identification of individual subjects based on FC matrices, with accuracies between 62 and 100%. Overall, pairings involving movies outperformed rest, and the more social and faster-paced movie attained 100% accuracy. When the parcellation resolution, scan duration and number of edges used were increased, accuracies improved across conditions, and the pattern of movies>rest was preserved. These results suggest that using dynamic stimuli such as movies enhances the detection of FC patterns that are distinct at the individual level.HighlightsIntra- and inter-subject FC correlations are compared across rest and movies.Movies outperformed rest in an unsupervised identification algorithm based on FC.Movies outperform rest regardless of parcellation, scan length, or number of edges.Watching movies enhances the detection of individual differences in FC.

2017 ◽  
Author(s):  
Corey Horien ◽  
Xilin Shen ◽  
Dustin Scheinost ◽  
R. Todd Constable

AbstractFunctional connectomes computed from fMRI provide a means to characterize individual differences in the patterns of BOLD synchronization across regions of the entire brain. Using four resting-state fMRI datasets with a wide range of ages, we show that individual differences of the functional connectome are stable across three months to three years. Medial frontal and frontoparietal networks appear to be both unique and stable, resulting in high ID rates, as did a combination of these two networks. We conduct analyses demonstrating that these results are not driven by head motion. We also show that the edges demonstrating the most individualized features tend to connect nodes in the frontal and parietal cortices, while edges contributing the least tend to connect cross-hemispheric homologs. Our results demonstrate that the functional connectome is stable across years and is not an idiosyncratic aspect of a specific dataset, but rather reflects stable individual differences in the functional connectivity of the brain.Research highlightsWhole-brain functional connectivity profiles obtained from four resting-state fMRI datasets are unique and stable across 3 months-3 years in adolescents, young adults, and older adultsMedial frontal and frontoparietal networks tended to be both unique and stableIndividual edges in the frontal and parietal cortices tended to be most discriminative of individual subjects


2010 ◽  
Vol 10 (2) ◽  
pp. 137-151 ◽  
Author(s):  
Paula Caligiuri ◽  
Saba Colakoglu ◽  
Jean-Luc Cerdin ◽  
Mee Sook Kim

This study explores cross-cultural and individual differences in predicting employer reputation as a driver of organizational attraction. Controlling for occupational and generational differences, this study examines the importance of employer reputation when choosing an employer among graduate engineering students in nine countries. At the cultural level, the impact of two cultural syndromes of individualism vs collectivism and verticalness vs horizontalness is examined. At the individual level, the influence of their needs for power and achievement is examined. Results suggest that, at the cultural level, collectivism and, at the individual level, need for power and achievement are related to the importance attached to employer reputation. In practice, companies should consider crafting their recruitment message to fit the cultural norms of the country where they are recruiting and also encourage their recruiting staff members to tailor their messages to fit the candidates they are trying to attract.


2021 ◽  
Vol 10 (6) ◽  
pp. 1161
Author(s):  
Raluca Pais ◽  
Thomas Maurel

The epidemiology and the current burden of chronic liver disease are changing globally, with non-alcoholic fatty liver disease (NAFLD) becoming the most frequent cause of liver disease in close relationship with the global epidemics of obesity, type 2 diabetes and metabolic syndrome. The clinical phenotypes of NAFLD are very heterogeneous in relationship with multiple pathways involved in the disease progression. In the absence of a specific treatment for non-alcoholic steatohepatitis (NASH), it is important to understand the natural history of the disease, to identify and to optimize the control of factors that are involved in disease progression. In this paper we propose a critical analysis of factors that are involved in the progression of the liver damage and the occurrence of extra-hepatic complications (cardiovascular diseases, extra hepatic cancer) in patients with NAFLD. We also briefly discuss the impact of the heterogeneity of the clinical phenotype of NAFLD on the clinical practice globally and at the individual level.


2021 ◽  
pp. 0258042X2199101
Author(s):  
Mukti Clarence ◽  
Viju P. D. ◽  
Lalatendu Kesari Jena ◽  
Tony Sam George

In the recent times, researchers have shown an increased interest in positive psychological capital (PsyCap). However, it is acknowledged that due to the limited number of studies conducted on the antecedents of psychological capital, there is a lack of sufficient data for conclusively proving the antecedents of PsyCap. Consequently, this article aims to explore the potential antecedents of PsyCap as a reliable source of data in the context of rural school teachers. The focus is to investigate both the individual differences and the contextual factors as desirable variables that constitute PsyCap among the school teachers of rural Jharkhand, India. Samples of 1,120 respondents from different rural schools were collected and analysed with Structural Equation Modeling (AMOS 20.0). The findings of the study explained that both the individual differences ( proactive personality and emotional intelligence) and the contextual factors ( perceived organizational support, servant leadership and meaningful work) have a positive relationship with PsyCap. The impact of PsyCap on teacher performance can form the basis for further research on the subject. JEL Codes: M12, M53


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Gerardo Chowell ◽  
Sushma Dahal ◽  
Raquel Bono ◽  
Kenji Mizumoto

AbstractTo ensure the safe operation of schools, workplaces, nursing homes, and other businesses during COVID-19 pandemic there is an urgent need to develop cost-effective public health strategies. Here we focus on the cruise industry which was hit early by the COVID-19 pandemic, with more than 40 cruise ships reporting COVID-19 infections. We apply mathematical modeling to assess the impact of testing strategies together with social distancing protocols on the spread of the novel coronavirus during ocean cruises using an individual-level stochastic model of the transmission dynamics of COVID-19. We model the contact network, the potential importation of cases arising during shore excursions, the temporal course of infectivity at the individual level, the effects of social distancing strategies, different testing scenarios characterized by the test’s sensitivity profile, and testing frequency. Our findings indicate that PCR testing at embarkation and daily testing of all individuals aboard, together with increased social distancing and other public health measures, should allow for rapid detection and isolation of COVID-19 infections and dramatically reducing the probability of onboard COVID-19 community spread. In contrast, relying only on PCR testing at embarkation would not be sufficient to avert outbreaks, even when implementing substantial levels of social distancing measures.


2022 ◽  
pp. 105984052110681
Author(s):  
Ashwini R. Hoskote ◽  
Emily Croce ◽  
Karen E. Johnson

School nurses are crucial to addressing adolescent mental health, yet evidence concerning their evolving role has not been synthesized to understand interventions across levels of practice (i.e., individual, community, systems). We conducted an integrative review of school nurse roles in mental health in the U.S. related to depressive symptoms, anxiety, and stress. Only 18 articles were identified, published from 1970 to 2019, and primarily described school nurses practicing interventions at the individual level, yet it was unclear whether they were always evidence-based. Although mental health concerns have increased over the years, the dearth of rigorous studies made it difficult to determine the impact of school nurse interventions on student mental health outcomes and school nurses continue to feel unprepared and under supported in this area. More research is needed to establish best practices and systems to support school nursing practice in addressing mental health at all levels of practice.


2015 ◽  
Vol 8 (4) ◽  
pp. 567-588 ◽  
Author(s):  
Carolin Rapp ◽  
Kathrin Ackermann

This paper scrutinizes the impact of intolerance toward diverse ethnic, religious, and cultural groups on an individual’s willingness to actively engage in non-violent protest. Following new insights, we examine the individual as well as the ecological effect of social intolerance on protest behavior. Drawing from insights of social psychology and communication science, we expect that the prevalence of intolerance reinforces the positive effect of individual-level intolerance on protest participation. From a rational choice perspective, however, a negative moderating effect is expected, as the expression of opinions becomes redundant for intolerant individuals in an intolerant society. We base our multilevel analyses on data from theWorld Values Surveyscovering 32 established democracies. Our results reveal that intolerance leads to more non-violent protest participation. This relationship, however, is strongly influenced by the prevalence of intolerance in a country.


2017 ◽  
Author(s):  
Yeun Kim ◽  
Jacqueline P. Ngo ◽  
Choi Deblieck ◽  
Dylan J. Edwards ◽  
Bruce Dobkin ◽  
...  

AbstractObjectiveWe assessed the individual level reliability of neural plasticity changes induced by paired associative stimulation (PAS), which combines peripheral nerve stimulation with transcranial magnetic stimulation to induce short-term plastic changes in the brain.MethodsFor 5 consecutive weeks, motor evoked potentials (MEPs) of 8 healthy subjects were acquired every 10 minutes post-PAS intervention for a period of 60 minutes. The post-PAS MEPs were evaluated against base-line MEPs using permutation and Kolmogorov-Smirnov tests to determine whether the MEP magnitudes changed after PAS. Moreover, various sample sizes of the MEP data were used to deduce the minimum number of MEPs needed to reliably detect individual propensity to neural plasticity.ResultsGroup analysis exhibited significant increase in post-PAS MEPs, confirming previous results. While high between-sessions variability was observed at individual level, data show that between 40 to 50 MEPs can reliably assess each subject’s responsiveness to PAS. Subjects exhibited three different plasticity patterns: in the modulated hemisphere only, both hemispheres, or neither hemisphere.ConclusionsPAS can reliably assess individual differences in neural plasticity.SignificanceA marker of individual plasticity may be useful to predict the effects of a motor rehabilitation, drug or other intervention to increase recovery of function after brain injury.HighlightsPaired associative stimulation (PAS) assesses neural plasticity non invasively.The study shows how PAS can reliably determine individual differences in plasticity.PAS may be used to predict intervention outcome or individualize treatment dose.


2018 ◽  
Vol 44 (5) ◽  
pp. 915-952
Author(s):  
Petra Kipfelsberger ◽  
Heike Bruch ◽  
Dennis Herhausen

This article investigates how and when a firm’s level of customer contact influences the collective organizational energy. For this purpose, we bridge the literature on collective human energy at work with the job impact framework and organizational sensemaking processes and argue that a firm’s level of customer contact is positively linked to the collective organizational energy because a high level of customer contact might make the experience of prosocial impact across the firm more likely. However, as prior research at the individual level has indicated that customers could also deplete employees’ energy, we introduce transformational leadership climate as a novel contingency factor for this linkage at the organizational level. We propose that a medium to high transformational leadership climate is necessary to derive positive meaning from customer contact, whereas firms with a low transformational leadership climate do not get energized by customer contact. We tested the proposed moderated mediation model with multilevel modeling and a multisource data set comprising 9,094 employees and 75 key informants in 75 firms. The results support our hypotheses and offer important theoretical contributions for research on collective human energy in organizations and its interplay with customers.


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