scholarly journals Global DNA methylation, as estimated in blood samples, does not correlate with variations of body condition, anatomical features and hematological parameters in American bullfrogs (Lithobates catesbeianus) kept captive under distinct environmental conditions

2017 ◽  
Author(s):  
Braulio Ayala García ◽  
Alma L. Fuentes-Farías ◽  
Gabriel Gutiérrez Ospina
Keyword(s):  
Dna Methylation ◽  
Environmental Conditions ◽  
Hematological Parameters ◽  
Gene Mutations ◽  
Global Dna Methylation ◽  
Lithobates Catesbeianus ◽  
American Bullfrog ◽  
Males And Females ◽  
Scaled Mass Index ◽  
The Relationship

AbstractDifferent levels of Global DNA Methylation (GDM) could have facilitated the emergence of new species, without relying on gene mutations, through promoting ontogenetic phenotypic plasticity. If this assertion was correct, one could expect individuals of the same species living under distinct environmental conditions to be genetically similar, but having different GDM levels and being phenotypically divergent. We tested this presumption by studying the relationship between variability of functional morphological traits and GDM levels in American bullfrog (Lithobates catesbeianus), in green houses located in two geographical sites. Our analyses revealed that body linear morphometry, skull geometry, scaled mass index, packed cell volume and neutrophil counts differed significantly among males and females within and between localities. GDM, nonetheless, was rather similar among sex and locality groups. These results show that levels of GDM, at least under our experimental contexts, does not correlate with functional morphological trait variability.

scholarly journals DNA methylation and cognitive functioning in healthy older adults

2011 ◽  
Vol 107 (5) ◽  
pp. 744-748 ◽  
Author(s):  
Olga J. G. Schiepers ◽  
Martin P. J. van Boxtel ◽  
Renate H. M. de Groot ◽  
Jelle Jolles ◽  
Frans J. Kok ◽  
...  
Keyword(s):  
Older Adults ◽  
Dna Methylation ◽  
Folic Acid ◽  
Cognitive Functioning ◽  
Cognitive Performance ◽  
Global Dna Methylation ◽  
Older Individuals ◽  
Healthy Older Adults ◽  
Study Results ◽  
The Relationship

Long-term supplementation with folic acid may improve cognitive performance in older individuals. The relationship between folate status and cognitive performance might be mediated by changes in methylation capacity, as methylation reactions are important for normal functioning of the brain. Although aberrant DNA methylation has been implicated in neurodevelopmental disorders, the relationship between DNA methylation status and non-pathological cognitive functioning in human subjects has not yet been investigated. The present study investigated the associations between global DNA methylation and key domains of cognitive functioning in healthy older adults. Global DNA methylation, defined as the percentage of methylated cytosine to total cytosine, was measured in leucocytes by liquid chromatography–MS/MS, in 215 men and women, aged 50–70 years, who participated in the Folic Acid and Carotid Intima-Media Thickness (FACIT) study (clinical trial registration number NCT00110604). Cognitive performance was assessed by means of the Visual Verbal Word Learning Task, the Stroop Colour-Word Interference Test, the Concept Shifting Test, the Letter–Digit Substitution Test and the Verbal Fluency Test. Using hierarchical linear regression analyses adjusted for age, sex, level of education, alcohol consumption, smoking status, physical activity, erythrocyte folate concentration and 5,10-methylenetetrahydrofolate reductase 677 C → T genotype, we found that global DNA methylation was not related to cognitive performance on any of the domains measured. The present study results do not support the hypothesis that global DNA methylation, as measured in leucocytes, might be associated with cognitive functioning in healthy older individuals.

Fine-grained investigation of the relationship between human nutrition and global DNA methylation patterns

2021 ◽  
Author(s):  
Fabrizia Noro ◽  
Annalisa Marotta ◽  
Marialaura Bonaccio ◽  
Simona Costanzo ◽  
Federica Santonastaso ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Human Nutrition ◽  
Global Dna Methylation ◽  
Fine Grained ◽  
Methylation Patterns ◽  
The Relationship

The Relationship Between Cognitive Impairment and Global DNA Methylation Decrease Among Aluminum Potroom Workers

2015 ◽  
Vol 57 (7) ◽  
pp. 713-717 ◽  
Author(s):  
Xiaojuan Yang ◽  
Yuzhou Yuan ◽  
Xiaoting Lu ◽  
Jin Yang ◽  
Linping Wang ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Cognitive Impairment ◽  
Global Dna Methylation ◽  
The Relationship

scholarly journals The relationship among sperm global DNA methylation, telomere length, and DNA fragmentation in varicocele: a cross-sectional study of 20 cases

2019 ◽  
Vol 65 (2) ◽  
pp. 95-104 ◽  
Author(s):  
Viviane Paiva Santana ◽  
Cristiana Libardi Miranda-Furtado ◽  
Daiana Cristina Chielli Pedroso ◽  
Matheus Credendio Eiras ◽  
Maria Aparecida Carneiro Vasconcelos ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Telomere Length ◽  
Dna Fragmentation ◽  
Cross Sectional Study ◽  
Global Dna Methylation ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Relationship

scholarly journals The relationship between transgenerational acquired resistance and global DNA methylation in Arabidopsis

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Joost H. M. Stassen ◽  
Ana López ◽  
Ritushree Jain ◽  
David Pascual-Pardo ◽  
Estrella Luna ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Acquired Resistance ◽  
Global Dna Methylation ◽  
The Relationship

Attachment and Field Dependence: Individual Differences in Information Processing

2004 ◽  
Vol 9 (1) ◽  
pp. 43-55 ◽  
Author(s):  
Patrizia Vermigli ◽  
Alessandro Toni
Keyword(s):  
Information Processing ◽  
Individual Differences ◽  
Field Dependence ◽  
Attachment Styles ◽  
Close Relationships ◽  
Adult Age ◽  
Males And Females ◽  
Figure Test ◽  
The Relationship ◽  
Measure Field

The present research analyzes the relationship between attachment styles at an adult age and field dependence in order to identify possible individual differences in information processing. The “Experience in Close Relationships” test of Brennan et al. was administered to a sample of 380 individuals (160 males, 220 females), while a subsample of 122 subjects was given the Embedded Figure Test to measure field dependence. Confirming the starting hypothesis, the results have shown that individuals with different attachment styles have a different way of perceiving the figure against the background. Ambivalent and avoidant individuals lie at the two extremes of the same dimension while secure individuals occupy the central part. Significant differences also emerged between males and females.

Global DNA Methylation is influenced by smoking behavior

2007 ◽  
Vol 40 (05) ◽  
Author(s):  
MAN Muschler ◽  
T Hillemacher ◽  
H Frieling ◽  
S Moskau ◽  
A Semmler ◽  
...  
Keyword(s):  
Dna Methylation ◽  
Smoking Behavior ◽  
Global Dna Methylation

scholarly journals Individual quality of life and the environment – towards a concept of livable areas for persons with disabilities in Poland

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Izabela Grabowska ◽  
Radosław Antczak ◽  
Jan Zwierzchowski ◽  
Tomasz Panek
Keyword(s):  
Quality Of Life ◽  
Environmental Conditions ◽  
Basic Research ◽  
Research Problem ◽  
Individual Characteristics ◽  
Living Conditions ◽  
Special Focus ◽  
Persons With Disabilities ◽  
The Relationship

Abstract Background The United Nations Convention on the Rights of Persons with Disabilities [1] highlights the need to create proper socioeconomic and political conditions for persons with disabilities, with a special focus on their immediate living conditions. According to the Convention, these conditions should be built to ensure that persons with disabilities have the potential to enjoy a high quality of life (QoL), and this principle is reflected in the notion of livable areas. The crucial aspect of this framework is the relationship between the individual QoL and the environment, broadly understood as the socioeconomic as well as the technical conditions in which persons with disabilities function. Methods The basic research problem was to assess the relationship between individual QoL for the population with disabilities as a dependent variable and livability indicators as independent variables, controlling for individual characteristics. The study used a dataset from the EU-SILC (European Union Statistics on Income and Living Conditions) survey carried out in 2015 in Poland. The research concept involved several steps. First, we created a variable measuring the QoL for the entire population with disabilities. To measure the multidimensional QoL, we used Sen’s capability approach as a general concept, which was operationalized by the MIMIC (multiple indicators multiple causes) model. In the second step, we identified the livability indicators available in the official statistics, and merged them with survey data. Finally, in the last step, we ran the regression analysis. We also checked the data for the nested structure. Results We confirmed that the general environmental conditions, focused on creating livable areas, played a significant role in shaping the QoL of persons with disabilities; i.e., we found that the higher the level of the local Human Development Index, the higher the quality of life of the individuals living in this area. This relationship held even after controlling for the demographic characteristics of the respondents. Moreover, we found that in addition to the general environmental conditions, the conditions created especially for persons with disabilities (i.e., services for this group and support for their living conditions) affected the QoL of these individuals. Conclusions The results illustrate the need to strengthen policies aimed at promoting the QoL of persons with disabilities by creating access to community assets and services that can contribute to improving the life chances of this population.

Metabolic, immunologic, and histopathologic responses on premetamorphic American bullfrog (Lithobates catesbeianus) following exposure to lithium and selenium

2020 ◽  
pp. 116086
Author(s):  
Felipe Augusto Pinto-Vidal ◽  
Cleoni dos Santos Carvalho ◽  
Fábio Camargo Abdalla ◽  
Letícia Ceschi-Bertoli ◽  
Heidi Samantha Moraes Utsunomiya ◽  
...  
Keyword(s):  
Lithobates Catesbeianus ◽  
American Bullfrog
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