scholarly journals A Statistical Analysis Of CoV-19 Positive Test Frequency Data Indicates A Need For Greater Attention To CoV-19 Test Quality And Pre-Wuhan Cov-19 Prevalence

2020 ◽  
Author(s):  
James L. Sherley
Keyword(s):  
Statistical Analysis ◽  
Epidemiological Data ◽  
Positive Test ◽  
Human Populations ◽  
Frequency Data ◽  
Test Frequency ◽  
Test Quality ◽  
Public Response ◽  
History Of ◽  
Improved Accuracy

AbstractIncreased attention to analysis of SARS-CoV-2 (CoV-19) positive test frequency data is essential for achievement of better knowledge of the natural history of the virus in human populations, improved accuracy of CoV-19 epidemiological data, and development of public response policies that are better crafted to address the current CoV-19-induced global crisis. A statistical analysis of currently available positive test frequency data reveals a surprisingly uniform relationship between the number of CoV-19 test performed and the number of positive tests obtained. The uniformity is particularly striking for United States CoV-19 test data. Such observations warrant closer evaluation of other factors, besides virus spread, that may also contribute to the nature of the coronavirus pandemic. These include indigenous CoV-19 and the quality of CoV-19 testing.

scholarly journals Prevalence of Antimicrobial Resistant Bacteria from Conjunctival Flora in an Eye Infection Prone Breed (Saint Bernard)

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2219
Author(s):  
George Cosmin Nadăș ◽  
Cristiana Ștefania Novac ◽  
Ioana Adriana Matei ◽  
Cosmina Maria Bouari ◽  
Zoltan Miklos Gal ◽  
...  
Keyword(s):  
Multidrug Resistant ◽  
Ocular Disease ◽  
Resistant Bacteria ◽  
Human Populations ◽  
Disease Treatment ◽  
Pseudomonas Spp ◽  
History Of ◽  
External Sources ◽  
Staphylococcus Spp ◽  
Saint Bernard

The conjunctival bacterial resident and opportunistic flora of dogs may represent a major source of dissemination of pathogens throughout the environment or to other animals and humans. Nevertheless, contamination with bacteria from external sources is common. In this context, the study of the antimicrobial resistance (AMR) pattern may represent an indicator of multidrug resistant (MDR) strains exchange. The present study was focused on a single predisposed breed—Saint Bernard. The evaluated animals were healthy, but about half had a history of ocular disease/treatment. The swabs collected from conjunctival sacs were evaluated by conventional microbiological cultivation and antimicrobial susceptibility testing (AST). The most prevalent Gram-positive was Staphylococcus spp.; regardless of the history, while Gram-negative was Pseudomonas spp.; exclusively from dogs with a history of ocular disease/treatment. Other identified genera were represented by Bacillus, Streptococcus, Trueperella, Aeromonas and Neisseria. The obtained results suggest a possible association between the presence of mixed flora and a history of ocular disease/treatment. A high AMR was generally observed (90%) in all isolates, especially for kanamycin, doxycycline, chloramphenicol and penicillin. MDR was recorded in Staphylococcus spp. and Pseudomonas spp. This result together with a well-known zoonotic potential may suggest an exchange of these strains within animal human populations and the environment.

scholarly journals Analysis of the relationship between periodontitis and osteoporosis/fractures: a cross-sectional study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Seok-Jin Hong ◽  
Byoung-Eun Yang ◽  
Dae-Myoung Yoo ◽  
Sung-Jae Kim ◽  
Hyo-Geun Choi ◽  
...  
Keyword(s):  
Odds Ratio ◽  
Bone Destruction ◽  
Epidemiological Data ◽  
Income Group ◽  
Cross Sectional Study ◽  
Inflammatory Factors ◽  
Sectional Study ◽  
Mineral Density ◽  
Cross Sectional ◽  
History Of

Abstract Background Chronic periodontitis is a multifactorial inflammatory disease resulting in patients exhibiting high levels of inflammatory factors causing systemic inflammatory bone destruction that may lead to osteoporosis development. The association between periodontitis and osteoporosis has been documented; however, the findings remain unclear. This study aimed to identify the association between periodontitis and osteoporosis using a cross-sectional study design and Korean Genome and Epidemiology Study (KoGES) health examinee data. Methods This cross-sectional study used epidemiological data from the KoGES during 2004–2016. Of 125,324 participants (age, 40–79 years), 9969 with periodontitis and 115,332 controls (without periodontitis) were selected. We analyzed the history of osteoporosis and fractures of all participants. All participants were examined according to age, sex, income group, obesity, smoking habits, alcohol consumption, and food intake. To analyze the odds ratio (OR) of periodontitis for those with osteoporosis and fractures, a logistic regression model was used. Results The adjusted odds ratio (aOR) of periodontitis for osteoporosis was 2.16 (95% confidence interval [CI], 2.01–2.31; P < 0.001). The aOR of periodontitis for any fracture was 1.54 (95% CI 1.46–1.62; P < 0.001). Conclusion Osteoporosis and fractures are associated with periodontitis. Performing regular oral hygiene and examinations of bone mineral density are recommended to prevent aggravation of osteoporosis and periodontitis.

scholarly journals Assessment of the Sexual Violence Situation in a Regional Hospital in Guatemala: The Need for a Multidisciplinary Clinic

2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S105-S105
Author(s):  
Blanca Soto ◽  
Miriam Canet ◽  
Diego Erdmenger
Keyword(s):  
Sexual Violence ◽  
Physical Violence ◽  
Negative Impact ◽  
Epidemiological Data ◽  
Depth Analysis ◽  
Significant Negative Impact ◽  
Comprehensive Health ◽  
History Of ◽  
Hepatitis B Testing

Abstract Background Sexual violence is a global health problem, in terms of age and sex, showing a significant negative impact on health. Incidence in Guatemala is among the highest of the region reaching an average of 23 cases reported daily nationally per statistics from the Ministry of Health in 2015. Methods Retrospective analysis of the database of all sexual violence cases reported from a secondary -level national hospital in Guatemala from January 2005 to September 2015 (period A) and in-depth analysis on demographic and epidemiological data along with information of the follow-up of cases between January 2012 and September 2015 (period B) was performed. Results Period A: 500 cases; female (96%; 481/500). Assault occurred between 16–20 years (34%; 163/481) 11–15 years (22.25%; 107/481), and 21–30 years (22.04%; 106/481). From all reported male cases, 73.68% (14/19) occurred under 15 years. Period B: 154/217 (70.96%) cases included; female (95.45%; 147/154), mean age: 17.87 years. Assault occurred in public spaces (57.14%; 88/154) and victim’s home (29.87%; 46/154). Almost 13% of victims reported history of previous assault, 5.84% by the same aggressor. More than one aggressor participated in 36.37% of assaults. Physical violence was associated in 57.79% of cases. Most victims (92.76%; 141/152) consulted within 72 hours of the assault. HIV, VDRL, and Hepatitis B testing performed in 100, 52, and 33.77%, respectively, were negative. Follow-up visits at 3, 6, and 12 months after the aggression were attended by 20.78% (30/154), 1.95% (3/154), and 1.95% (3/154) of victims, respectively. Psychology support was completed only in 18.18% (28/154). Emergency contraception was provided when indicated; pregnancy as result of the aggression was reported in nine cases (5.84%). Conclusion The study shows that young women were the most vulnerable group for sexual violence. There is a lack of multidisciplinary approach and follow-up. Interventions on infectious diseases screening have to be optimized to reduce the risk of ETS transmission. This evidence supports the need for a specialized clinic to ensure access to comprehensive health services for victims. Disclosures All authors: No reported disclosures.

scholarly journals Irish consequences of the Great War

2015 ◽  
Vol 39 (156) ◽  
pp. 643-658 ◽  
Author(s):  
David Fitzpatrick
Keyword(s):  
Social History ◽  
Final Section ◽  
Civil Conflict ◽  
Great War ◽  
Irish History ◽  
Public Response ◽  
Recent Scholarship ◽  
History Of ◽  
The Great War ◽  
The Postponement

AbstractIt is now widely admitted that the Great War was also Ireland’s war, with profound consequences for every element of Irish life after 1914. Its impact may be discerned in aberrant aspects of Ireland’s demographic, economic and social history, as well as in the more familiar political and military convulsions of the war years. This article surveys recent scholarship, assesses statistical evidence of the war’s social and economic impact (both positive and negative), and explores its far-reaching political repercussions. These include the postponement of expected civil conflict, the unexpected occurrence of an unpopular rebellion in 1916, and public response to the consequent coercion. The speculative final section outlines a number of plausible outcomes for Irish history in the absence of war, concluding that no single counterfactual history of a warless Ireland is defensible.

Was This in Your Statistics Textbook? IV. Frequency Data

1989 ◽  
Vol 25 (1) ◽  
pp. 11-25
Author(s):  
D. J. Finney
Keyword(s):  
Statistical Analysis ◽  
Contingency Tables ◽  
The Other ◽  
Frequency Data ◽  
Significance Tests ◽  
Test Statistic ◽  
Jumping To Conclusions ◽  
Proper Role ◽  
Measure Of Association

SUMMARYObservations that are frequencies rather than measurements often call for special types of statistical analysis. This paper comments on circumstances in which methods for one type of data can sensibly be used for the other. A section on two-way contingency tables emphasizes the proper role of χ2 a test statistic but not a measure of association; it mentions the distinction between one-tail and two-tail significance tests and reminds the reader of dangers. Multiway tables bring new complications, and the problems of interactions when additional classificatory factors are explicit or hidden are discussed at some length. A brief outline attempts to show how probit, logit, and similar techniques are related to the analysis of contingency tables. Finally, three unusual examples are described as illustrations of the care that is needed to avoid jumping to conclusions on how frequency data should be analysed.

Sequence variation and evolution of nuclear DNA in man and the primates

1981 ◽  
Vol 292 (1057) ◽  
pp. 133-142 ◽  
Keyword(s):  
Dna Sequence ◽  
Sequence Variation ◽  
Nuclear Dna ◽  
Sequence Divergence ◽  
Gene Arrangement ◽  
Human Populations ◽  
Genetic Changes ◽  
Detailed Structural Analysis ◽  
Dna Sequence Variation ◽  
History Of

Recent advances in nucleic acid technology have facilitated the detection and detailed structural analysis of a wide variety of genes in higher organisms, including those in man. This in turn has opened the way to an examination of the evolution of structural genes and their surrounding and intervening sequences. In a study of the evolution of haemoglobin genes and neighbouring sequences in man and the primates, we have investigated gene arrangement and DNA sequence divergence both within and between species ranging from Old World monkeys to man. This analysis is beginning to reveal the evolutionary constraints that have acted on this region of the genome during primate evolution. Furthermore, DNA sequence variation, both within and between species, provides, in principle, a novel and powerful method for determining inter-specific phylogenetic distances and also for analysing the structure of present-day human populations. Application of this new branch of molecular biology to other areas of the human genome should prove important in unravelling the history of genetic changes that have occurred during the evolution of man.

Uno studio sulle presidenziali americane: l'economia conta?

2012 ◽  
pp. 41-55
Author(s):  
Marco Morini
Keyword(s):  
Statistical Analysis ◽  
Presidential Elections ◽  
Economic Indicators ◽  
Economic Data ◽  
The Real ◽  
Approval Rating ◽  
History Of ◽  
Electoral Behaviour

The economy matters. This is one of the dogmas taught us by those who have studied the history of the American presidential elections. But is this collective perception of the influence of economic data on individual electoral behaviour confirmed by statistical analysis of the history of presidential elections? This study shows that the most commonly used economic indicators are poor predictors of election outcomes, and also that variation in the approval rating of the incumbent president is a variable independent from the real economic data.

Features hormonal status in pregnant women with benign cervical pathology in anamnesis

2017 ◽  
pp. 71-73
Author(s):  
N.Yu. Bysaha ◽  
Keyword(s):  
Statistical Analysis ◽  
Pregnant Women ◽  
Placental Lactogen ◽  
Control Group ◽  
Hormonal Status ◽  
Hormonal Changes ◽  
Fetoplacental Complex ◽  
History Of ◽  
Objective Study ◽  
Stimulation Of

The objective: study of hormonal status in pregnant women with benign cervical pathology (CP) in anamnesis. Patients and methods. Clinical and statistical analysis of the hormonal status of 100 women with a history of benign CP pathology has been performed. According to the revealed symptoms of CP during colposcopic examination, women were divided into two groups: 100 pregnant women, in whom colposcopic and cytologically signs of CP pathology were not detected, were included in the control group; and 100 women who had a pathology of CP, entered the main group. Results. The study examined hormonal relationships in the system mother–placenta–fetus, namely the level of hormones such as estriol, progesterone, human chorionic gonadotropin, placental lactogen. Hormonal changes in pregnant women and contribute to reducing the immunoreactivity unwanted stimulation of existing benign hyperplastic background processes in the cervix. Conclusion. Determining functional state placenta is an important factor in the timely diagnosis of disorders in the functioning of the system mother–placenta–fetus. Key words: hormonal status, placenta, uterine cervix, fetoplacental complex.

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