scholarly journals Self-powered piezo-bioelectronic device mediates tendon repair through modulation of mechanosensitive ion channels

2020 ◽  
Author(s):  
Marc A. Fernandez-Yague ◽  
Alex Trotier ◽  
Sunny Akogwu Abbah ◽  
Aitor Larrañaga ◽  
Arun Thirumaran ◽  
...  
Keyword(s):  
Piezoelectric Materials ◽  
Tendon Repair ◽  
Ferroelectric Material ◽  
Achilles Tendinopathy ◽  
Body Motion ◽  
Channel Modulation ◽  
Repair Processes ◽  
Bioelectronic Device ◽  
Self Powered ◽  
Specific Tissue

AbstractTendon disease constitutes an unmet clinical need and remains a critical challenge in the field of orthopaedic surgery. Innovative solutions are required to overcome the limitations of current tendon grafting approaches, and bioelectronic therapies are showing promise in the treatment of musculoskeletal disease, accelerating functional recovery through the activation of tissue regeneration signalling pathways (guided regeneration). Self-powered bioelectronic devices, and in particular piezoelectric materials represent a paradigm shift in biomedicine, negating the need for battery or external powering and complementing existing mechanotherapy to accelerate the repair processes. Here, we show the dynamic response of tendon cells to a piezoelectric collagen-analogue scaffold comprised of aligned nanoscale fibres made of the ferroelectric material poly(vinylidenefluoride-co-trifluoroethylene), (PVDF-TrFE). We demonstrate that electromechanical stimulation of tendon tissue results in guided regeneration by ion channel modulation. Finally, we show the potential of the bioelectronic device in regulating the progression of tendinopathy associated processes using a rat Achilles tendinopathy model. This study indicates that body motion-powered electromechanical stimulation can control the expression of TRPA1 and PIEZO2 receptors and stimulate tendon-specific tissue repair processes.

scholarly journals Flexible Multiscale Pore Hybrid Self-Powered Sensor for Heart Sound Detection

Sensors ◽  
2021 ◽  
Vol 21 (13) ◽  
pp. 4508
Author(s):  
Boyan Liu ◽  
Liuyang Han ◽  
Lyuming Pan ◽  
Hongzheng Li ◽  
Jingjing Zhao ◽  
...  
Keyword(s):  
Piezoelectric Coefficient ◽  
Heart Sound ◽  
Piezoelectric Materials ◽  
Ferroelectric Material ◽  
Flexible Sensor ◽  
Β Phase ◽  
Short Processing Time ◽  
Sound Detection ◽  
Corona Poling ◽  
Self Powered

This research introduces an idea of producing both nanoscale and microscale pores in piezoelectric material, and combining the properties of the molecular β-phase dipoles in ferroelectric material and the space charge dipoles in order to increase the sensitivity of the sensor and modulate the response frequency bandwidth of the material. Based on this idea, a bi-nano-micro porous dual ferro-electret hybrid self-powered flexible heart sound detection sensor is proposed. Acid etching and electrospinning were the fabrication processes used to produce a piezoelectric film with nanoscale and microscale pores, and corona poling was used for air ionization to produce an electret effect. In this paper, the manufacturing process of the sensor is introduced, and the effect of the porous structure and corona poling on improving the performance of the sensor is discussed. The proposed flexible sensor has an equivalent piezoelectric coefficient d33 of 3312 pC/N, which is much larger than the piezoelectric coefficient of the common piezoelectric materials. Experiments were carried out to verify the function of the flexible sensor together with the SS17L heart sound sensor (BIOPAC, Goleta, CA, USA) as a reference. The test results demonstrated its practical application for wearable heart sound detection and the potential for heart disease detection. The proposed flexible sensor in this paper could realize batch production, and has the advantages of flexibility, low production cost and a short processing time compared with the existing heart sound detection sensors.

Stretchable-Rubber-Based Triboelectric Nanogenerator and Its Application as Self-Powered Body Motion Sensors

2015 ◽  
Vol 25 (24) ◽  
pp. 3688-3696 ◽  
Author(s):  
Fang Yi ◽  
Long Lin ◽  
Simiao Niu ◽  
Po Kang Yang ◽  
Zhaona Wang ◽  
...  
Keyword(s):  
Body Motion ◽  
Triboelectric Nanogenerator ◽  
Motion Sensors ◽  
Self Powered

scholarly journals All 3D Printed Stretchable Piezoelectric Nanogenerator for Self-Powered Sensor Application

Sensors ◽  
2020 ◽  
Vol 20 (23) ◽  
pp. 6748
Author(s):  
Xinran Zhou ◽  
Kaushik Parida ◽  
Oded Halevi ◽  
Shlomo Magdassi ◽  
Pooi See Lee
Keyword(s):  
Piezoelectric Materials ◽  
Mechanical Energy ◽  
Rapid Development ◽  
The Internet ◽  
Electronic Systems ◽  
3D Printed ◽  
Wearable Electronic ◽  
Self Powered ◽  
The Internet Of Things ◽  
Piezoelectric Nanogenerators

With the rapid development of wearable electronic systems, the need for stretchable nanogenerators becomes increasingly important for autonomous applications such as the Internet-of-Things. Piezoelectric nanogenerators are of interest for their ability to harvest mechanical energy from the environment with its inherent polarization arising from crystal structures or molecular arrangements of the piezoelectric materials. In this work, 3D printing is used to fabricate a stretchable piezoelectric nanogenerator which can serve as a self-powered sensor based on synthesized oxide–polymer composites.

A Novel Multi-Directional Nonlinear Piezoelectric Energy Harvester Coupled With Nonlinear Conditioning Circuits

2015 ◽  
Author(s):  
Zhengbao Yang ◽  
Jean Zu
Keyword(s):  
Energy Harvester ◽  
Piezoelectric Materials ◽  
Electrical Energy ◽  
Elastic Rods ◽  
Energy Harvesters ◽  
Piezoelectric Energy ◽  
High Power Output ◽  
Transduction Mechanisms ◽  
Self Powered ◽  
Aluminum Plates

Energy harvesting from vibrations has become, in recent years, a recurring target of a quantity of research to achieve self-powered operation of low-power electronic devices. However, most of energy harvesters developed to date, regardless of different transduction mechanisms and various structures, are designed to capture vibration energy from single predetermined direction. To overcome the problem of the unidirectional sensitivity, we proposed a novel multi-directional nonlinear energy harvester using piezoelectric materials. The harvester consists of a flexural center (one PZT plate sandwiched by two bow-shaped aluminum plates) and a pair of elastic rods. Base vibration is amplified and transferred to the flexural center by the elastic rods and then converted to electrical energy via the piezoelectric effect. A prototype was fabricated and experimentally compared with traditional cantilevered piezoelectric energy harvester. Following that, a nonlinear conditioning circuit (self-powered SSHI) was analyzed and adopted to improve the performance. Experimental results shows that the proposed energy harvester has the capability of generating power constantly when the excitation direction is changed in 360. It also exhibits a wide frequency bandwidth and a high power output which is further improved by the nonlinear circuit.

Shape Memory Polymers for Body Motion Energy Harvesting and Self-Powered Mechanosensing

2018 ◽  
Vol 30 (8) ◽  
pp. 1705195 ◽  
Author(s):  
Ruiyuan Liu ◽  
Xiao Kuang ◽  
Jianan Deng ◽  
Yi-Cheng Wang ◽  
Aurelia C. Wang ◽  
...  
Keyword(s):  
Energy Harvesting ◽  
Shape Memory ◽  
Shape Memory Polymers ◽  
Body Motion ◽  
Motion Energy ◽  
Self Powered

Load-Tolerant, High-Efficiency Self-Powered Energy Harvesting Scheme Using a Nonlinear Approach

2014 ◽  
Vol 1 (3-4) ◽  
Author(s):  
Mickaël Lallart ◽  
Claude Richard ◽  
Yang Li ◽  
Yi-Chieh Wu ◽  
Daniel Guyomar
Keyword(s):  
Energy Harvesting ◽  
High Efficiency ◽  
Piezoelectric Materials ◽  
Small Scale ◽  
Energy Scavenging ◽  
Resistive Load ◽  
Vibration Energy Harvesting ◽  
New Approach ◽  
Nonlinear Approach ◽  
Self Powered

AbstractSmall-scale energy harvesting has become a particularly hot topic for replacing batteries in autonomous or nomad systems. In particular, vibration energy harvesting using piezoelectric elements has experienced a significant amount of research over the last decade as vibrations are widely available in many environments and as piezoelectric materials can be easily embedded. However, the energy scavenging abilities of such systems are still limited and are very sensitive to the connected load. The purpose of this paper is to expose a new approach based on synchronous switching on resistive load, which allows both a significant enhancement of the energy harvesting capabilities as well as a high tolerance to a change of the impedance of the connected system, especially in the low value region. It is theoretically and experimentally shown that such an approach permits increasing the energy harvesting abilities by a factor 4 compared to classical DC energy harvesting approach. Furthermore, the self-powering possibility and automatic load adaptation of the proposed method is experimentally discussed, showing the realistic viability of the technique.

scholarly journals Deposition of Energy using Piezoelectric Material and its Application in TPMS

2021 ◽  
Vol 9 (VI) ◽  
pp. 4236-4241
Author(s):  
Vishal Singh
Keyword(s):  
Piezoelectric Material ◽  
Electromechanical Coupling ◽  
Vibrational Energy ◽  
Piezoelectric Materials ◽  
Electronic Systems ◽  
Ambient Vibrations ◽  
Tire Pressure ◽  
Sufficient Energy ◽  
Tire Pressure Monitoring System ◽  
Self Powered

The limited lifespan in portable, remote and implantable devices and the need to recharge or replace batteries periodically has been a consistent issue. Ambient energy can usually be found in the form of thermal energy, vibrational energy and solar energy. Among these energy sources, vibrational energy presents a constant presence in nature and artificial structures. Energy harvesting through piezoelectric materials by extracting power from ambient vibrations is a promising technology. The material is capable to harvest sufficient energy required to make autonomous and self-powered electronic systems. The characteristic of piezoelectric material is electromechanical coupling between electrical and mechanical domains. The design of a piezoelectric device for the purpose of storing the kinetic energy of random vibrations at the wheel of a vehicle is presented. The harvester is optimized to power the Tire Pressure Monitoring System (TPMS). The aim is to make of the value of power and voltage outputs for different input frequency conditions. A typical TPMS system consists of a battery operated one, in this paper bimorph is designed to powering a TPMS commercial feasibility of this option is compared to existing TPMS modules, which require batteries for operation.

Powering Healthcare IoT Sensors-Based Triboelectric Nanogenerator

2020 ◽  
pp. 29-51
Author(s):  
Saeed Ahmed Khan ◽  
Shamsuddin Lakho ◽  
Ahmed Ali ◽  
Abdul Qadir Rahimoon ◽  
Izhar Hussain Memon ◽  
...  
Keyword(s):  
Human Body ◽  
Pressure Sensors ◽  
Wearable Devices ◽  
Temperature Sensors ◽  
The Body ◽  
Body Motion ◽  
Triboelectric Nanogenerator ◽  
Self Powered ◽  
Fitness Tracking ◽  
Triboelectric Nanogenerators

Most of the emerging electronic devices are wearable in nature. However, the frequent changing or charging the battery of all wearable devices is the big challenge. Interestingly, with those wearable devices that are directly associated with the human body, the body can be used in transferring or generating energy in a number of techniques. One technique is triboelectric nanogenerators (TENG). This chapter covers different applications where the human body is used as a triboelectric layer and as a sensor. Wearable TENG has been discussed in detail based on four basic modes that could be used to monitor the human health. In all the discussions, the main focus is to power the wearable healthcare internet of things (IoT) sensor through human body motion based on self-powered TENG. The IoT sensors-based wearable devices related to human body can be used to develop smart body temperature sensors, pressure sensors, smart textiles, and fitness tracking sensors.

Repair of Chronic Achilles Ruptures Has a High Incidence of Venous Thromboembolism

2016 ◽  
Vol 10 (5) ◽  
pp. 415-420 ◽  
Author(s):  
Mark J. Bullock ◽  
William T. DeCarbo ◽  
Mark H. Hofbauer ◽  
Joshua D. Thun
Keyword(s):  
Venous Thromboembolism ◽  
Achilles Tendon ◽  
Achilles Tendon Rupture ◽  
Tendon Repair ◽  
Achilles Tendinopathy ◽  
Flexor Hallucis Longus ◽  
Achilles Tendon Repair ◽  
Elective Repair ◽  
High Incidence ◽  
Tendon Ruptures

Background. Despite the low incidence of deep vein thrombosis (DVT) in foot and ankle surgery, some authors report a high incidence of symptomatic DVT following Achilles tendon rupture. The purpose of this study was to identify DVT risk factors inherent to Achilles tendon repair to determine which patients may benefit from prophylaxis. Methods. One hundred and thirteen patient charts were reviewed following elective and nonelective Achilles tendon repair. For elective repair of insertional or noninsertional Achilles tendinopathy, parameters examined included lateral versus prone positioning and the presence versus absence of a flexor hallucis longus transfer. For nonelective repair, acute Achilles tendon ruptures were compared to chronic Achilles tendon ruptures. Results. Of 113 Achilles tendon repairs, 3 venous thromboembolism (VTE) events (2.65%) occurred including 2 pulmonary emboli (1.77%). Seventeen of these repairs were chronic Achilles tendon ruptures, and all 3 VTE events (17.6%) occurred within this subgroup. Elevated body mass index was associated with VTE in patients with chronic Achilles ruptures although this did not reach significance ( P = .064). No VTE events were reported after repair of 28 acute tendon ruptures or after 68 elective repairs of tendinopathy. Two patients with misdiagnosed partial Achilles tendon tears were excluded because they experienced a VTE event 3 weeks and 5 weeks after injury, prior to surgery. Conclusion. In our retrospective review, chronic Achilles ruptures had a statistically significant higher incidence of VTE compared with acute Achilles ruptures ( P = .048) or elective repair ( P = .0069). Pharmaceutical anticoagulation may be considered for repair of chronic ruptures. Repair of acute ruptures and elective repair may not warrant routine prophylaxis due to a lower incidence of VTE. Levels of Evidence: Prognostic, Level III: Case Control Study

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