Clinical, Laboratory, and Imaging Features of 148 Patients with COVID-19 in Bushehr: A Report from the South of Iran

Aim: To investigate clinical characteristics, laboratory findings, and imaging features of patients confirmed with COVID-19 in Bushehr, a southern province of Iran. Method: During April 29th to May 30th 2020, a total of 148 patients confirmed with COVID-19 infection were admitted to three hospitals in Bushehr province, assigned by the Iranian Ministry of Health. Results: The most common coexisting disease was type 2 diabetes. Levels of ESR, CRP, LDH, and AST among inpatients were higher than the outpatients (P<0.05). There were significant differences in the levels of creatinine and BUN between elderly and non-elderly patients (P<0.05). Conclusion: Patients with comorbidities and elderly patients are at increased risk of severe progression of COVID-19.

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Clinical characteristics of outpatients and inpatients with COVID-19 in Bushehr: a report from the south of Iran

Future Virology ◽

10.2217/fvl-2020-0231 ◽

2021 ◽

Author(s):

Mohsen Keshavarz ◽

Ahmad Tavakoli ◽

Sareh Zanganeh ◽

Mohammad Javad Mousavi ◽

Katayoun Vahdat ◽

...

Keyword(s):

Computed Tomography ◽

Renal Failure ◽

Lactate Dehydrogenase ◽

Elderly Patients ◽

Clinical Characteristics ◽

Clinical Laboratory ◽

Imaging Features ◽

Severe Renal Failure ◽

Erythrocyte Sedimentation ◽

Increased Risk

Aim: To investigate clinical, laboratory and imaging features of COVID-19 patients in Bushehr, a southern province of Iran. Materials & methods: A total of 148 COVID-19 patients were enrolled. The patients were categorized into four groups including inpatients, outpatients, elderly and nonelderly. Clinical, laboratory and computed tomography characteristics were analyzed and compared. Results: Levels of erythrocyte sedimentation rate, CRP, lactate dehydrogenase and aspartate aminotransferas among inpatients were higher than outpatients. There were significant differences in the levels of creatinine and blood urine nitrogen between elderly and nonelderly patients. The incidence of ground-glass opacities in inpatients was significantly higher than in outpatients. Conclusion: COVID-19 is associated with more severe renal failure in elderly patients. Elderly patients with underlying conditions are at increased risk of severe progression of COVID-19.

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Sodium Intake and Incidence of Diabetes Complications in Elderly Patients with Type 2 Diabetes—Analysis of Data from the Japanese Elderly Diabetes Intervention Study (J-EDIT)

Nutrients ◽

10.3390/nu13020689 ◽

2021 ◽

Vol 13 (2) ◽

pp. 689

Author(s):

Chika Horikawa ◽

Rei Aida ◽

Shiro Tanaka ◽

Chiemi Kamada ◽

Sachiko Tanaka ◽

...

Keyword(s):

Type 2 Diabetes ◽

Diabetic Retinopathy ◽

Elderly Patients ◽

Diabetes Complications ◽

Vegetable Intake ◽

Sodium Intake ◽

Food Groups ◽

High Sodium ◽

Increased Risk

This study investigates the associations between sodium intake and diabetes complications in a nationwide cohort of elderly Japanese patients with type 2 diabetes aged 65–85. Data from 912 individuals regarding their dietary intake at baseline is analyzed and assessed by the Food Frequency Questionnaire based on food groups. Primary outcomes are times to diabetic retinopathy, overt nephropathy, cardiovascular disease (CVD), and all-cause mortality during six years. We find that mean sodium intake in quartiles ranges from 2.5 g to 5.9 g/day. After adjustment for confounders, no significant associations are observed between sodium intake quartiles and incidence of diabetes complications and mortality, except for a significant trend for an increased risk of diabetic retinopathy (p = 0.039). Among patients whose vegetable intake was less than the average of 268.7 g, hazard ratios (HRs) for diabetic retinopathy in patients in the second, third, and fourth quartiles of sodium intake compared with the first quartile were 0.87 (95% CI, 0.31–2.41), 2.61 (1.00–6.83), and 3.70 (1.37–10.02), respectively. Findings indicate that high sodium intake under conditions of low vegetable intake is associated with an elevated incidence of diabetic retinopathy in elderly patients with type 2 diabetes.

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Renal Complication and Glycemic Control in Korean Veterans with Type 2 Diabetes: A 10-Year Retrospective Cohort Study

Journal of Diabetes Research ◽

10.1155/2020/9806790 ◽

2020 ◽

Vol 2020 ◽

pp. 1-13

Author(s):

Ye An Kim ◽

Young Lee ◽

Je Hyun Seo

Keyword(s):

Type 2 Diabetes ◽

Cohort Study ◽

Glycemic Control ◽

Elderly Patients ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Diabetes Complications ◽

Hazard Ratios ◽

Increased Risk

Objective. Tight glycemic control reduces the risk of diabetes complications, but it may increase the risk of hypoglycemia or mortality in elderly patients. This study is aimed at evaluating the incidence and progression of renal complications and its association with glycemic control in elderly patients with type 2 diabetes. Methods. This retrospective cohort study examined the data of 3099 patients with type 2 diabetes who were followed for at least 10 years at the Korean Veterans Hospital and for whom glycated hemoglobin (HbA1c) was measured in 2008 and 2017. Participants were divided into six groups according to their baseline or dynamic HbA1c levels. Extended Cox models were used to calculate adjusted hazard ratios for the development of chronic kidney disease (CKD) and end-stage renal disease (ESRD) associated with specific HbA1c ranges. Results. During the 10-year follow-up period, 30% of patients developed new CKD, 50% showed progression, and ESRD developed in 1.7%. The risk of CKD was associated with baseline HbA1c from the first year of the study and dynamic HbA1c throughout the study period. The adjusted hazard ratios for CKD were 1.98 and 2.32 for baseline and dynamic HbA1c, respectively, at the level of ≥69 mmol/mol. There was no increased risk for any complications in baseline and dynamic HbA1c below 58 mmol/mol. Conclusions. A higher HbA1c≥58 mmol/mol was associated with an increased risk of diabetes complications. A less stringent glycemic target of HbA1c could be used as the threshold of renal complications.

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