scholarly journals Systematic review and meta-analyses on the prevalence of dementia in Latin America and Caribbean countries: Exploring sex, rurality, age, and education as possible determinants

2021 ◽  
Author(s):  
Fabiana S Ribeiro ◽  
Ana C. Teixeira-Santos ◽  
Paulo Caramelli ◽  
Anja K. Leist
Keyword(s):  
Latin America ◽  
Formal Education ◽  
Random Effects Model ◽  
Dementia Prevalence ◽  
Pooled Prevalence ◽  
Latin America And Caribbean ◽  
The Caribbean ◽  
One Year ◽  
Meta Analyses ◽  
Prevalence Of Dementia

Background: Studies have shown that the prevalence of dementia in Latin America and the Caribbean (LAC) may be higher than in high-income countries. Thus, we sought to systematically analyse the prevalence of dementia and explore possible drivers that lead to this disparity in LAC countries. Method: We searched Pubmed, Web of Knowledge, Scopus, Lilacs, and SciELO for studies on dementia in LAC countries in English, Spanish, and Portuguese languages. Random-effects model was applied. Results: Twenty-nine studies from 12 LAC countries were included. Pooled prevalence of all-cause dementia was 11%. Further analyses with studies providing raw prevalence by sex, area, and educational level showed a higher prevalence for women (9%) than for men (5%). Also, dementia prevalence was higher for rural than urban residents (12% vs 8%, respectively). Participants without formal education presented more than double the prevalence of dementia (22%) compared to those with at least one year of formal education (10%). Studies with more recent data collection showed higher dementia prevalence. Conclusion: Our findings suggest a high global dementia prevalence in LAC countries and an unequal burden of dementia for women, lower-educated, and rural residents. Secular raises in dementia prevalence call for increased public health efforts for preventative action.

3 Estimating the Burden of Dementia in Latin America and the Caribbean: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 50 (Supplement_1) ◽  
pp. i1-i6
Author(s):  
Y Xiang ◽  
K Chan ◽  
I Rudan
Keyword(s):  
Latin America ◽  
Disease Burden ◽  
Meta Analysis ◽  
Public Health Issue ◽  
Middle Income ◽  
Dementia Prevalence ◽  
Pooled Prevalence ◽  
The Future ◽  
The Caribbean ◽  
Policy And Planning

Abstract Background and Objectives Rapid increase in life expectancy has resulted in an increase in the global burden of dementia that is expected to become a leading cause of morbidity in the future. Low- and middle-income countries are expected to bear an increasing majority of the burden, but lack data for accurate burden estimates that are key for informing policy and planning. Bayesian methods have recently gained recognition over traditional frequentist approaches for modelling disease burden for their superiority in dealing with severely limited data. This study provides updated estimates of dementia prevalence in Latin America and the Caribbean (LAC) for the years 2015, 2020 and 2030. Given the paucity of data, estimates were developed using a Bayesian methodology and confirmed by the traditional frequentist approach, with the aim of providing methodological insights for future disease burden estimates. Methods A comprehensive systematic literature search was conducted to identify all relevant primary studies published between the years 2010–2018. The quality of the included studies was critically assessed. A random-effects model (REM) and a Bayesian normal-normal hierarchical model (NNHM) were used to obtain the pooled prevalence estimate of dementia for people aged 60 and above. The latter model was also developed to estimate age-specific dementia prevalence. Using UN population estimates, total and age-specific projections of the burden of dementia were calculated. Results The prevalence of dementia in LAC was found to be 14% (10–21%) in those above age 60 based on REM, and 8% (5–11.5%) based on NNHM. The prevalence increased from 2% (1–4%) in people aged 60–69 to 29% (20–37%) in people above the age of 80. The number of people living with dementia in LAC in 2015 was estimated at 5.68 million, with future projections of 6.86 million in 2020 and 9.94 million in 2030. Conclusions The findings of this review found that burden of dementia in LAC is substantial and continues to rapidly grow. The projected rise in dementia cases in the future should prompt urgent governmental response to address this growing public health issue. We were also able to demonstrate that given the overall paucity of data, a Bayesian approach was superior for estimating disease prevalence and burden.

scholarly journals Prevalence of Dementia Among the Elderly in Latin America and the Caribbean: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 482-482
Author(s):  
Fabiana Ribeiro ◽  
Ana Carolina Teixeira-Santos ◽  
Anja Leist
Keyword(s):  
Latin America ◽  
Rural Areas ◽  
Meta Analysis ◽  
Inclusion Criteria ◽  
Care Needs ◽  
Comprehensive Overview ◽  
Dementia Prevalence ◽  
People With Dementia ◽  
The Caribbean ◽  
Prevalence Of Dementia

Abstract Background Over the last decades, life expectancy in Latin America and the Caribbean showed a rapid increase, which led to a significant increase in the number of people with dementia. Moreover, 9% of the population in this part of the world are aged 65 or older, and by 2050 this percentage is projected to at least double. For this reason, it is essential to estimate the prevalence of dementia in LAC countries with the aim to determine suitable actions to enhance the quality of life of those affected. Methods Database searches for articles were conducted September 2020 throughout Pubmed, Web of knowledge, Scopus, Lilacs, and SciELO. The inclusion criteria comprised population- or community-based studies, published in English, Spanish, or Portuguese, reporting data on the prevalence of dementia collected in LAC countries. The complete data search retrieved 1719 non-duplicates. Results A total of 58 studies met the high-quality inclusion criteria, published 1991-2020, including participants in the following countries: Brazil, Mexico, Argentina, Colombia, Peru, Cuba, Dominican Republic, Venezuela, Ecuador, Trinidad and Tobago, and Jamaica. The most common form of dementia studied was Alzheimer’s disease with prevalence ranging from 5.9% to 23.4%. Estimates differed by age, gender, and education, with oldest, women, and lower-educated adults living in rural areas presenting higher dementia prevalence. Conclusion This is the first study giving a comprehensive overview of dementia prevalence in LAC countries, which is relevant to estimate care needs and economic costs related to dementia treatment and care.

scholarly journals Actual and predicted prevalence of alcohol consumption during pregnancy in Latin America and the Caribbean: systematic literature review and meta-analysis

2017 ◽  
Vol 41 ◽  
pp. 1
Author(s):  
Svetlana Popova ◽  
Shannon Lange ◽  
Charlotte Probst ◽  
Navrose Heer ◽  
Michael Roerecke ◽  
...  
Keyword(s):  
Latin America ◽  
Alcohol Consumption ◽  
General Population ◽  
Meta Analysis ◽  
Fetal Alcohol ◽  
Data Prediction ◽  
Pooled Prevalence ◽  
The Caribbean ◽  
Meta Analyses ◽  
Fetal Alcohol Spectrum

ObjectiveTo estimate the prevalence of alcohol consumption during pregnancy among the general population of Latin America and the Caribbean, by country, in 2012.MethodsThree steps were taken: a comprehensive, systematic literature search; meta-analyses, assuming a random-effects model for countries with published studies; and regression modelling (data prediction) for countries with either no published studies or too few to obtain an estimate.ResultsBased on 24 existing studies, the pooled prevalence of alcohol consumption during pregnancy among the general population was estimated for Brazil (15.2%; 95% confidence interval [95%CI]: 10.4%–20.8%) and Mexico (1.2%; 95%CI: 0.0%–2.7%). The prevalence of alcohol consumption during pregnancy among the general population was predicted for 31 countries and ranged from 4.8% (95%CI: 4.2%–5.4%) in Cuba to 23.3% (95%CI: 20.1%–26.5%) in Grenada.ConclusionsGreater prevention efforts and measures are needed in the countries of Latin America and the Caribbean to prevent pregnant women from consuming alcohol during pregnancy and decrease the rates of Fetal Alcohol Spectrum Disorder. Additional high quality studies on the prevalence of alcohol consumption during pregnancy in Latin America and the Caribbean are also needed.

scholarly journals Epidemiology of herpes simplex virus type 2 in Latin America and the Caribbean: systematic review, meta-analyses and metaregressions

2021 ◽  
pp. sextrans-2021-054972
Author(s):  
Manale Harfouche ◽  
Haifa Maalmi ◽  
Laith J Abu-Raddad
Keyword(s):  
Latin America ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Genital Herpes ◽  
Sex Workers ◽  
The Caribbean ◽  
General Populations ◽  
Simplex Virus ◽  
Meta Analyses

ObjectiveTo characterise epidemiology of herpes simplex virus type 2 (HSV-2) in Latin America and the Caribbean.MethodsHSV-2 reports were systematically reviewed and synthesised, and findings were reported following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Meta-analyses and metaregressions were conducted.Finding102 relevant reports were identified including 13 overall incidence measures, 163 overall (and 402 stratified) seroprevalence measures, and 7 and 10 proportions of virus detection in genital ulcer disease and in genital herpes, respectively. Pooled mean seroprevalence was 20.6% (95% CI 18.7% to 22.5%) in general populations, 33.3% (95% CI 26.0% to 41.0%) in intermediate-risk populations, 74.8% (95% CI 70.6% to 78.8%) in female sex workers, and 54.6% (95% CI 47.4% to 61.7%) in male sex workers, men who have sex with men and transgender people. In general populations, seroprevalence increased from 9.6% (95% CI 7.1% to 12.4%) in those aged <20 years to 17.9% (95% CI 13.6% to 22.5%) in those aged 20–30, 27.6% (95% CI 21.4% to 34.2%) in those aged 30–40 and 38.4% (95% CI 32.8% to 44.2%) in those aged >40. Compared with women, men had lower seroprevalence with an adjusted risk ratio (ARR) of 0.68 (95% CI 0.60 to 0.76). Seroprevalence declined by 2% per year over the last three decades (ARR of 0.98, 95% CI 0.97 to 0.99). Pooled mean proportions of HSV-2 detection in GUD and genital herpes were 41.4% (95% CI 18.9% to 67.0%) and 91.1% (95% CI 82.7% to 97.2%), respectively.ConclusionsOne in five adults is HSV-2 infected, a higher level than other world regions, but seroprevalence is declining. Despite this decline, HSV-2 persists as the aetiological cause of nearly half of GUD cases and almost all of genital herpes cases.

Thinking Regional on Peace Missions in Latin America

2017 ◽  
Vol 21 (3-4) ◽  
pp. 177-196
Author(s):  
Monica Hirst
Keyword(s):  
Latin America ◽  
Latin American ◽  
The United States ◽  
Post Cold War ◽  
Peace Processes ◽  
Post Conflict ◽  
Open Case ◽  
Response Capacity ◽  
Latin America And Caribbean ◽  
The Caribbean

As is the case with other regions, in Latin America and the Caribbean, multilateral peace missions are subordinated to norms and expectations of specific mandates. Yet, post-Cold War peace missions in Latin America and the Caribbean share circumstances that are unique to this region. This article seeks to offer a sequenced overview of three scenarios – Central America, Haiti and Colombia – to show how these circumstances interplay as shaping factors in regional peace missions. Three circumstances are highlighted: i) the strategic irrelevance of the region; ii) the preeminence of the United States in Latin America and the Caribbean; iii) the response capacity of Latin American governments. These three are addressed as the core cast of determinants in post-conflict contexts in Latin America and Caribbean. This article explores how these circumstances have adapted in time producing reiterative dynamics attuned to international and regional changing landscapes. Even though the Colombian experience should be considered “an open case”, its inclusion contributes to enrich this argument. Final reflections raise the question if these circumstances explain as well the failures and reversed expectations of regional peace processes.

Systematic Review of Second Primary Oropharyngeal Cancers in Patients With p16+ Oropharyngeal Cancer

2020 ◽  
pp. 019459982095117
Author(s):  
Craig A. Bollig ◽  
David S. Lee ◽  
Angela L. Mazul ◽  
Katelyn Stepan ◽  
Sidharth V. Puram ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Random Effects ◽  
Meta Analysis ◽  
Second Primary ◽  
Random Effects Model ◽  
Treatment Information ◽  
Pooled Prevalence ◽  
Alive With Disease ◽  
Medical Librarian ◽  
Meta Analyses

Objective To systematically review the literature to determine the prevalence and clinical outcomes of second primary oropharyngeal squamous cell carcinoma (OPSCC). Data Sources Search strategies created with a medical librarian were implemented using multiple databases in October 2019. Review Methods The population of interest included adults age >18 years with a p16+ or human papillomavirus-positive OPSCC. The outcome was a synchronous or metachronous second primary OPSCC. Inclusion and exclusion criteria were designed to capture all study designs. In total, 685 records were identified by the search strategy. Two reviewers independently performed the review, extracted data, and performed a quality assessment. Primary Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed. A random-effects model was used for the meta-analysis. Results A total of 2470 patients with 35 second primary OPSCCs from 15 studies were identified. The pooled prevalence of second primary OPSCC was 1.4% (range, 0%-14.3%). In the random-effects model, the prevalence was estimated at 1.3% (95% CI, 0.7%-2.3%; P = .51, I2 = 52%). Of the 30 patients with treatment information, 26 (86.7%) received surgical treatment, while 4 (13.3%) underwent nonsurgical therapy. Of the 29 patients with available survival information, 22 (75.9%) had no evidence of disease at last follow-up, 5 (17.2%) ultimately died of disease, and 2 (6.9%) were alive with disease. Conclusion Overall, the rate of second primary OPSCC in patients with an index p16+ OPSCC is low, and most patients are successfully treated. Insufficient evidence currently exists to recommend routine elective tonsillectomy during surgical treatment of p16+ OPSCC.

scholarly journals L’America Latina: tra nuovo nazionalismo e secolarismo

2009 ◽  
Vol 58 (2) ◽  
Author(s):  
Alberto G. Bochatey
Keyword(s):  
Quality Of Life ◽  
Latin America ◽  
Scientific Progress ◽  
Modern Biology ◽  
Ethical Pluralism ◽  
Descriptive Ethics ◽  
Latin America And Caribbean ◽  
The Caribbean ◽  
Cultural Reality

Il pluralismo etico della società civile moderna considera, in genere, buono tutto quel che è autorizzato dalle leggi realizzate democraticamente e considera cattivo il contrario. Ciò vale anche per l’America Latina ed i Caraibi? Come vengono percepite le leggi in questi Paesi? Il contributo tenta di rispondere a questi interrogativi. La risposta è che è assente una critica e uno studio oggettivo e ragionato su quali interventi dell’Uomo nel campo della biologia moderna, della ricerca, della medicina, del riconoscimento di certi valori indiscutibili siano eticamente leciti. Molti di questi ambiti non sono regolati da leggi e in alcuni casi non sono nemmeno conosciuti dalla popolazione. I bioeticisti dell’America Latina e dei Carabi devono essere, dunque, attenti alla realtà di quei popoli senza applicare teorie elaborate in altri contesti. In altri termini, un’etica descrittiva non è sufficiente, ma occorre far riferimento alla realtà oggettiva e culturale della persona, al fine di promuovere il progresso scientifico ed il miglioramento della qualità della vita. ---------- The ethical pluralism of the modern civil society considers, generally, as good all that is authorized by the laws democratically realized and it considers the contrary as bad. Is this also equivalent in Latin America and the Caribbean? How are the laws perceived in these Countries? The contribution tries to answer to these questions. The answer is that a criticism and an objective and reasoned study is absent on what interventions of the Man in the field of the modern biology, of the search, of the medicine, of the recognition of certain indisputable values is ethically permissible. Many of these circles are not regulated by laws and in some cases they are not even known by the population. The bioethicists of Latin America and Caribbean have to be, therefore, careful to the reality of that people without applying theories elaborated in other contexts. In other terms, a descriptive ethics is not enough, but it is necessary to make reference to the objective and cultural reality of the person, with the purpose to promote the scientific progress and the improvement of the quality of life.

La brecha de ciberseguridad en América Latina frente al contexto global de ciberamenazas

2020 ◽  
Vol 6 (2) ◽  
pp. 17-43
Author(s):  
Juan Manuel Aguilar Antonio
Keyword(s):  
Latin America ◽  
Cyber Security ◽  
Economic Losses ◽  
Individual Level ◽  
Cyber Threats ◽  
Latin America And Caribbean ◽  
The Caribbean ◽  
America Latina ◽  
Definition Of ◽  
The Individual

This research is based on the hypothesis that the governments of Latin America and the Caribbean are lagging behind in the construction of cyber defense capabilities to face the international context of cyber threats, with respect to the member countries of North Atlantic Treaty Organization (NATO), both in the organizational plan, as in the individual. To prove this statement, the text is divided into six sections. The first part presents the global environment of cyber threats, the economic losses suffered by governments and companies according to reports from information security firms such as Kaspersky, Microsoft, Verizon and International Business Machines Corporation (IBM). The second part presents the internet securitization process, the immersion of cybersecurity in national security studies, and the definition of cyber capabilities and the delimitation of threats to the Nation-State from cyberspace are addressed. The third part shows the trajectory of NATO as an organization in the development of cyber capabilities in the last twenty years. In the fourth part, a set of National Cybersecurity Strategies (ENCS) of NATO countries and allies is analyzed from the individual level, from which their main elements are extracted and their general anatomy is outlined. In the sixth part, an approach to different regional or global cybersecurity environments is presented based on measurements of the Global Cybersecurity Index (GCI), of the International Telecommunications Union (ITU), and the National Cyber Security Index (NSCI) of the Estonian E-Governance Academy. The fifth section presents the context of cybersecurity in Latin America and the Caribbean, according to studies made by the Inter-American Development Bank (IDB) and the Organization of American States (OAS), as well as private cybersecurity firms. In the sixth, two case studies of Mexico, from the 2019-2020, are briefly presented, which represent the lack of maturity of its ENCS and development of cyber capabilities, an aspect that it shares with most of the countries of Latin America and Caribbean. Finally, brief conclusions are presented on the aspects to be strengthened by the region.

Patterns of insecticide resistance in Aedes aegypti : meta‐analyses of surveys in Latin America and the Caribbean

2020 ◽  
Vol 76 (6) ◽  
pp. 2144-2157
Author(s):  
Raul Narciso C Guedes ◽  
Kaley Beins ◽  
Dennis Navarro Costa ◽  
Giovanini E Coelho ◽  
Haroldo Sérgio da S Bezerra
Keyword(s):  
Latin America ◽  
Aedes Aegypti ◽  
Insecticide Resistance ◽  
The Caribbean ◽  
Meta Analyses

scholarly journals Prevalence of dementia in ischaemic or mixed stroke populations: systematic review and meta-analysis

2021 ◽  
pp. jnnp-2020-325796
Author(s):  
Louise Craig ◽  
Zhi Liang Hoo ◽  
Toh Zeng Yan ◽  
Joanna Wardlaw ◽  
Terence J Quinn
Keyword(s):  
Meta Analysis ◽  
Sensitivity Analyses ◽  
Random Effects Models ◽  
Dementia Prevalence ◽  
Pooled Prevalence ◽  
High Prevalence ◽  
Apparent Reduction ◽  
Quantitative Analyses ◽  
Prestroke Dementia ◽  
Prevalence Of Dementia

An understanding of the epidemiology of poststroke dementia (PSD) is necessary to inform research, practice and policy. With increasing primary studies, a contemporary review of PSD could allow for analyses of incidence and prevalence trends. Databases were searched using a prespecified search strategy. Eligible studies described an ischaemic or mixed stroke cohort with prospective clinical assessment for dementia. Pooled prevalence of dementia was calculated using random-effects models at any time after stroke (primary outcome) and at 1 year (range: 6–18 months), stratified for inclusion of prestroke dementia. Meta-regression explored the effect of year of study. Sensitivity analyses removed low-quality or outlier studies. Of 12 505 titles assessed, 44 studies were included in the quantitative analyses. At any time point after stroke, the prevalence of PSD was 16.5% (95% CI 10.4% to 25.1%) excluding prestroke dementia and 22.3% (95% CI 18.8% to 26.2%) including prestroke dementia. At 1 year, the prevalence of PSD was 18.4% (95% CI 7.4% to 38.7%) and 20.4% (95% CI 14.2% to 28.2%) with prestroke dementia included. In studies including prestroke dementia there was a negative association between dementia prevalence and year of study (slope coefficient=−0.05 (SD: 0.01), p<0.0001). Estimates were robust to sensitivity analyses. Dementia is common following stroke. At any point following stroke, more than one in five people will have dementia, although a proportion of this dementia predates the stroke. Declining prevalence of prestroke dementia may explain apparent reduction in PSD over time. Risk of dementia following stroke remains substantial and front-loaded, with high prevalence at 1 year post event.

Sign in / Sign up

Export Citation Format

Share Document