scholarly journals A new fMRI localizer for preoperative language mapping using a sentence completion task: Validity, choice of baseline condition, and test-retest reliability

2021 ◽  
Author(s):  
Kirill Elin ◽  
Svetlana Malyutina ◽  
Oleg Bronov ◽  
Ekaterina Stupina ◽  
Aleksei Marinets ◽  
...  
Keyword(s):  
Baseline Condition ◽  
Sentence Completion ◽  
Angular Gyrus ◽  
Language Function ◽  
Parietal Region ◽  
Retest Reliability ◽  
Completion Task ◽  
Neurosurgical Patients ◽  
Test Retest Reliability ◽  
The Brain

To avoid post-neurosurgical language deficits, intraoperative mapping of the language function in the brain can be complemented with preoperative mapping with fMRI. The validity of an fMRI language localizer paradigm crucially depends on the choice of an optimal language task and baseline condition. This study presents a new fMRI language localizer in Russian using overt sentence completion, a task that comprehensively engages the language function by involving both production and comprehension at the word and sentence level. The paradigm was validated in 18 neurologically healthy volunteers who participated in two scanning sessions, for estimating test-retest reliability. For the first time, two baseline conditions for the sentence completion task were compared. At the group level, the paradigm significantly activated both anterior and posterior language-related regions. Individual-level analysis showed that activation was elicited most consistently in the inferior frontal regions, followed by posterior temporal regions and the angular gyrus. Test-retest reliability of activation location, as measured by Dice coefficients, was moderate and thus comparable to previous studies. Test-retest reliability was higher in the frontal than temporo-parietal region and with the most liberal statistical thresholding compared to two more conservative thresholding methods. Lateralization indices were expectedly left-hemispheric, with greater lateralization in the frontal than temporo-parietal region, and showed moderate test-retest reliability. Finally, the pseudoword baseline elicited more extensive and more reliable activation, although the syllable baseline appears more feasible for future clinical use. Overall, the study demonstrated the validity and reliability of the sentence completion task for mapping the language function in the brain. The paradigm needs further validation in a clinical sample of neurosurgical patients. Additionally, the study contributes to general evidence on test-retest reliability of fMRI.

scholarly journals The Brain Metastases Symptom Checklist as a novel tool for symptom measurement in patients with brain metastases undergoing whole-brain radiotherapy

2016 ◽  
Vol 23 (3) ◽  
pp. 239 ◽  
Author(s):  
D. Rodin ◽  
B. Banihashemi ◽  
L. Wang ◽  
A. Lau ◽  
S. Harris ◽  
...  
Keyword(s):  
Brain Metastases ◽  
Intraclass Correlation ◽  
Whole Brain Radiotherapy ◽  
Assessment Tools ◽  
Symptom Checklist ◽  
Retest Reliability ◽  
Brain Radiotherapy ◽  
Test Retest Reliability ◽  
The Brain ◽  
Responsiveness To Change

Purpose We evaluated the feasibility, reliability, and validity of the Brain Metastases Symptom Checklist (BMSC), a novel self-report measure of common symptoms experienced by patients with brain metastases.Methods Patients with first-presentation symptomatic brain metastases (n = 137) referred for whole-brain radiotherapy (WBRT) completed the BMSC at time points before and after treatment. Their caregivers (n = 48) provided proxy ratings twice on the day of consultation to assess reliability, and at week 4 after WBRT to assess responsiveness to change. Correlations with 4 other validated assessment tools were evaluated.Results The symptoms reported on the BMSC were largely mild to moderate, with tiredness (71%) and difficulties with balance (61%) reported most commonly at baseline. Test–retest reliability for individual symptoms had a median intraclass correlation of 0.59 (range: 0.23–0.85). Caregiver proxy and patient responses had a median intraclass correlation of 0.52. Correlation of absolute scores on the BMSC and other symptom assessment tools was low, but consistency in the direction of symptom change was observed. At week 4, change in symptoms was variable, with improvements in weight gain and sleep of 42% and 41% respectively, and worsening of tiredness and drowsiness of 62% and 59% respectively.Conclusions The BMSC captures a wide range of symptoms experienced by patients with brain metastases, and it is sensitive to change. It demonstrated adequate test–retest reliability and face validity in terms of its responsiveness to change. Future research is needed to determine whether modifications to the BMSC itself or correlation with more symptom-specific measures will enhance validity. 

scholarly journals Test–Retest Reliability of Synchrony and Metastability in Resting State fMRI

2021 ◽  
Vol 12 (1) ◽  
pp. 66
Author(s):  
Lan Yang ◽  
Jing Wei ◽  
Ying Li ◽  
Bin Wang ◽  
Hao Guo ◽  
...  
Keyword(s):  
Resting State ◽  
Resting State Fmri ◽  
Resting State Networks ◽  
Functional Magnetic Resonance ◽  
Intra Class Correlation ◽  
Retest Reliability ◽  
Brain Signals ◽  
Human Connectome Project ◽  
Test Retest Reliability ◽  
The Brain

In recent years, interest has been growing in dynamic characteristic of brain signals from resting-state functional magnetic resonance imaging (rs-fMRI). Synchrony and metastability, as neurodynamic indexes, are considered as one of methods for analyzing dynamic characteristics. Although much research has studied the analysis of neurodynamic indices, few have investigated its reliability. In this paper, the datasets from the Human Connectome Project have been used to explore the test–retest reliabilities of synchrony and metastability from multiple angles through intra-class correlation (ICC). The results showed that both of these indexes had fair test–retest reliability, but they are strongly affected by the field strength, the spatial resolution, and scanning interval, less affected by the temporal resolution. Denoising processing can help improve their ICC values. In addition, the reliability of neurodynamic indexes was affected by the node definition strategy, but these effects were not apparent. In particular, by comparing the test–retest reliability of different resting-state networks, we found that synchrony of different networks was basically stable, but the metastability varied considerably. Among these, DMN and LIM had a relatively higher test–retest reliability of metastability than other networks. This paper provides a methodological reference for exploring the brain dynamic neural activity by using synchrony and metastability in fMRI signals.

Test-Retest Reliability of the Brain Injury Vision Symptom Survey

2018 ◽  
pp. 177-185
Keyword(s):  
Brain Injury ◽  
Limits Of Agreement ◽  
Retest Reliability ◽  
Visual Symptoms ◽  
Significant Bias ◽  
Moderate Traumatic Brain Injury ◽  
Significant Difference ◽  
History Of ◽  
Test Retest Reliability ◽  
The Brain

Background: Assessment of the test-retest reliability of the Brain Injury Vision Symptom Survey (BIVSS), a self-administered survey for visual symptoms following mild to moderate traumatic brain injury (TBI). Methods: Subjects (n=130, mean age 37 +/- 17.6, range 19 to 55) with mild-to-moderate TBI completed the 28-item BIVSS questionnaire two times (1-hr to 4-month separation interval). 25 subjects reported a history of medically diagnosed TBI, 5 an undiagnosed TBI, and 14 no history of injury. 87 subjects did not select a type of TBI diagnosis and were analyzed in the ‘not specified’ group. A scoring algorithm was developed for the BIVSS,1 and Rasch and Likert analyses performed. Bland-Altman charts illustrating methods of analyses were created and limits of agreement calculated. Results: A one sample t-test performed on both analyses for each patient group revealed no significant bias in scoring higher or lower on retest for any group with the exception of the ‘not specified’ group and Rasch analysis (n=87, t=3.41, p=0.01). When time between survey administrations is restricted to two weeks or less however, we see no significant difference for any group. Bland-Altman charts with 95% limits of agreement (+/- 0.40) revealed no significant change in direction of bias (Likert: p=0.92; Rasch: p=0.52) and consistency in distribution of values on retest (Likert: r=0.91; Rasch: r=0.25); the first administration accounting for 82.6% (r2) of variance at the second administration. Conclusions: The BIVSS has very good test retest reliability, and can serve as a suitable tool for assessing and quantifying visual symptoms associated with mild to moderate TBI. There is no significant bias in total BIVSS score between test administrations for either patients who have experienced TBI or non-injured patients. Future analysis of change in BIVSS subset scores concurrent with intervention could potentially reveal relationships between improvement in objective measurements and specific subjective subset scores.

Test–Retest Reliability of the Brain Metabolites GABA and Glx With JPRESS, PRESS, and MEGA‐PRESS MRS Sequences in vivo at 3T

2019 ◽  
Vol 51 (4) ◽  
pp. 1181-1191 ◽  
Author(s):  
Arwa Baeshen ◽  
Patrik O. Wyss ◽  
Anke Henning ◽  
Ruth L. O'Gorman ◽  
Marco Piccirelli ◽  
...  
Keyword(s):  
Brain Metabolites ◽  
Retest Reliability ◽  
Test Retest Reliability ◽  
The Brain

The Test of Orientation for Rehabilitation Patients: Test-Retest Reliability

1992 ◽  
Vol 12 (3) ◽  
pp. 172-185 ◽  
Author(s):  
Jean C. Deitz ◽  
Vicky S. Tovar ◽  
Clara Beeman ◽  
Deborah W. Thorn ◽  
Michael S. Trevisan
Keyword(s):  
Brain Injury ◽  
Repeated Measures ◽  
Brain Injuries ◽  
Intraclass Correlation ◽  
Retest Reliability ◽  
Reliability Estimates ◽  
Injury Group ◽  
Temporal Continuity ◽  
Test Retest Reliability ◽  
The Brain

The Test of Orientation for Rehabilitation Patients was developed for assessing the orientation of inpatients with brain injuries in rehabilitation settings. The test is composed of 46 items grouped into five domains of orientation: 1) Person and Personal Situation, 2) Place, 3) Time, 4) Schedule, and 5) Temporal Continuity. Test-retest reliability and magnitudes of difference between scores on test and retest were examined using subgroups of 30 rehabilitation patients with brain injuries and 32 rehabilitation patients without brain injuries. The interval between test and retest ranged from 3 to 5 days. Test-retest reliability estimates (using the two-way random effects repeated measures model of the intraclass correlation coefficient) for the total test scores were good (r = .85) to excellent (r = .95) for the non-brain-injury and brain-injury groups, respectively. Reliability coefficients for the domain scores were higher for the brain-injury group than the non-brain-injury group. However, when agreements between test and retest scores were examined, the non-brain-injury group showed greater stability.

Measuring “Language Access Profiles” in Deaf and Hard-of-Hearing Children With the DHH Language Exposure Assessment Tool

2020 ◽  
pp. 1-25
Author(s):  
Matthew L. Hall ◽  
Stephanie De Anda
Keyword(s):  
Cluster Analysis ◽  
Exposure Assessment ◽  
Hard Of Hearing ◽  
Assessment Tool ◽  
Communication Mode ◽  
Developmental Potential ◽  
Language Access ◽  
Retest Reliability ◽  
Language Exposure ◽  
Test Retest Reliability

Purpose The purposes of this study were (a) to introduce “language access profiles” as a viable alternative construct to “communication mode” for describing experience with language input during early childhood for deaf and hard-of-hearing (DHH) children; (b) to describe the development of a new tool for measuring DHH children's language access profiles during infancy and toddlerhood; and (c) to evaluate the novelty, reliability, and validity of this tool. Method We adapted an existing retrospective parent report measure of early language experience (the Language Exposure Assessment Tool) to make it suitable for use with DHH populations. We administered the adapted instrument (DHH Language Exposure Assessment Tool [D-LEAT]) to the caregivers of 105 DHH children aged 12 years and younger. To measure convergent validity, we also administered another novel instrument: the Language Access Profile Tool. To measure test–retest reliability, half of the participants were interviewed again after 1 month. We identified groups of children with similar language access profiles by using hierarchical cluster analysis. Results The D-LEAT revealed DHH children's diverse experiences with access to language during infancy and toddlerhood. Cluster analysis groupings were markedly different from those derived from more traditional grouping rules (e.g., communication modes). Test–retest reliability was good, especially for the same-interviewer condition. Content, convergent, and face validity were strong. Conclusions To optimize DHH children's developmental potential, stakeholders who work at the individual and population levels would benefit from replacing communication mode with language access profiles. The D-LEAT is the first tool that aims to measure this novel construct. Despite limitations that future work aims to address, the present results demonstrate that the D-LEAT represents progress over the status quo.

Visual-Neural Correlate of Speechreading Ability in Normal-Hearing Adults

1982 ◽  
Vol 25 (4) ◽  
pp. 521-527 ◽  
Author(s):  
David C. Shepherd
Keyword(s):  
Normal Hearing ◽  
Wave Form ◽  
Firing Time ◽  
Neural Firing ◽  
Neural Correlate ◽  
Retest Reliability ◽  
Repeated Word ◽  
Negative Peak ◽  
The Stability ◽  
Test Retest Reliability

In 1977, Shepherd and colleagues reported significant correlations (–.90, –.91) between speechreading scores and the latency of a selected negative peak (VN 130 measure) on the averaged visual electroencephalic wave form. The primary purpose of this current study was to examine the stability, or repeatability, of this relation between these cognitive and neurophysiologic measures over a period of several months and thus support its test-retest reliability. Repeated speechreading word and sentence scores were gathered during three test-retest sessions from each of 20 normal-hearing adults. An average of 56 days occurred from the end of one to the beginning of another speechreading sessions. During each of four other test-retest sessions, averaged visual electroencephalic responses (AVER s ) were evoked from each subject. An average of 49 clays intervened between AVER sessions. Product-moment correlations computed among repeated word scores and VN l30 measures ranged from –.61 to –.89. Based on these findings, it was concluded that the VN l30 measure of visual neural firing time is a reliable correlate of speech-reading in normal-hearing adults.

Test-Retest Reliability of a Self-Report Questionnaire for DSM-IV and ICD-10 Personality Disorders

2000 ◽  
Vol 16 (1) ◽  
pp. 53-58 ◽  
Author(s):  
Hans Ottosson ◽  
Martin Grann ◽  
Gunnar Kullgren
Keyword(s):  
Personality Disorder ◽  
Anxiety Disorders ◽  
Personality Disorders ◽  
Clinical Sample ◽  
Self Report ◽  
Anxiety State ◽  
Short Term ◽  
Retest Reliability ◽  
Axis I ◽  
Test Retest Reliability

Summary: Short-term stability or test-retest reliability of self-reported personality traits is likely to be biased if the respondent is affected by a depressive or anxiety state. However, in some studies, DSM-oriented self-reported instruments have proved to be reasonably stable in the short term, regardless of co-occurring depressive or anxiety disorders. In the present study, we examined the short-term test-retest reliability of a new self-report questionnaire for personality disorder diagnosis (DIP-Q) on a clinical sample of 30 individuals, having either a depressive, an anxiety, or no axis-I disorder. Test-retest scorings from subjects with depressive disorders were mostly unstable, with a significant change in fulfilled criteria between entry and retest for three out of ten personality disorders: borderline, avoidant and obsessive-compulsive personality disorder. Scorings from subjects with anxiety disorders were unstable only for cluster C and dependent personality disorder items. In the absence of co-morbid depressive or anxiety disorders, mean dimensional scores of DIP-Q showed no significant differences between entry and retest. Overall, the effect from state on trait scorings was moderate, and it is concluded that test-retest reliability for DIP-Q is acceptable.

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