scholarly journals Automated and rapid self-report of nociception in transgenic mice

2019 ◽  
Author(s):  
Christopher J. Black ◽  
Anusha B. Allawala ◽  
Kiernan Bloye ◽  
Kevin N. Vanent ◽  
Muhammad M. Edhi ◽  
...  

AbstractA time-resolved, conscious report of detected nociceptive stimuli in mice offers an opportunity to examine the relationship between higher order neural circuits and pain perception. We have developed a detection behavior in transgenic mice that leverages temporally precise and cell-specific stimulation to elicit self-reports of nociception. Conscious reporting of peripheral nociceptive input may help identify neural mechanisms that generate pain perception.

Crisis ◽  
2019 ◽  
Vol 40 (6) ◽  
pp. 413-421 ◽  
Author(s):  
Megan L. Rogers ◽  
Thomas E. Joiner

Abstract. Background: Acute suicidal affective disturbance (ASAD) has been proposed as a suicide-specific entity that confers risk for imminent suicidal behavior. Preliminary evidence suggests that ASAD is associated with suicidal behavior beyond a number of factors; however, no study to date has examined potential moderating variables.  Aims: The present study tested the hypotheses that physical pain persistence would moderate the relationship between ASAD and (1) lifetime suicide attempts and (2) attempt lethality. Method: Students ( N = 167) with a history of suicidality completed self-report measures assessing the lifetime worst-point ASAD episode and the presence of a lifetime suicide attempt, a clinical interview about attempt lethality, and a physical pain tolerance task. Results: Physical pain persistence was a significant moderator of the association between ASAD and lifetime suicide attempts ( B = 0.00001, SE = 0.000004, p = .032), such that the relationship between ASAD and suicide attempts strengthened at increasing levels of pain persistence. The interaction between ASAD and pain persistence in relation to attempt lethality was nonsignificant ( B = 0.000004, SE = 0.00001, p = .765). Limitations: This study included a cross-sectional/retrospective analysis of worst-point ASAD symptoms, current physical pain perception, and lifetime suicide attempts. Conclusion: ASAD may confer risk for suicidal behavior most strongly at higher levels of pain persistence, whereas ASAD and pain perception do not influence attempt lethality.


1998 ◽  
Vol 83 (1) ◽  
pp. 316-318 ◽  
Author(s):  
Elisardo Becoña ◽  
Fernando L. Vazquez

In this study was evaluated the relationship between self-reported smoking rate and expired air carbon monoxide in 208 smokers who had attended a behavioral program for smoking cessation. A close relationship between carbon monoxide levels and self-reports was found at the end of treatment and in all follow-ups (6 and 12 mo.), around 100% concordance. Thus, support was found for the use of an expired air carbon monoxide measure as a valid and easy way of corroborating self-report data when required.


Introduction: Both in personality assessment and scientific research, self-report questionnaires are frequently used, yet the use of informant-report is increasing. The aim of this systematic review is to address the concordance and added value of informant- versus self-report in measuring personality pathology in (older) adults. Method: A systematic search has been carried out for relevant literature published between 2000 and 2018, via the databases Scopus, PsychINFO and PubMED. Also the reference lists of included articles have been checked, resulting in an inclusion of 46 studies. Results: The concordance between informant- and self-report appears to be only moderate, but highest when the relationship is characterized by interpersonal intimacy (such as between partners). The concordance between informants is somewhat better than between informant- and self -reports. Informants have an added value over self-report in the context of externalizing personality traits and interpersonal functioning. In addition, they appear to be a better predictor for health, adaptability and professional functioning. Self-report on the other hand captures intrapsychic characteristics more thoroughly. Conclusion: In personality assessment, informant- and self-reports could be complementary. However, empirical research among older adults is almost uncharted territory and deserves more attention.


1982 ◽  
Vol 50 (3_suppl) ◽  
pp. 1160-1162 ◽  
Author(s):  
Ira Daniel Turkat

This report details a test of the validity of long-term estimates of medical utilization rate among a chronically ill population. The relationship between diabetics' reported frequencies of ambulatory visits to the Diabetes Center over an 18-mo. period and clinic recorded data were evaluated. A high, positive, and significant correlation was observed, providing support for the validity of self-reports. An unexpected finding was that 60% of the subjects over-estimated frequency of clinic visits. The need for empirical assessment of this commonly used measure is discussed.


2018 ◽  
Vol 33 (4) ◽  
pp. 238-242 ◽  
Author(s):  
Clara Gallego Cerveró ◽  
Julio Martín Ruiz ◽  
Laura Ruiz Sanchis ◽  
Concepción Ros Ros

BACKGROUND: Wind musicians suffer injuries resulting from muscle overuse and poor postural habits, often due to the lack of required physical fitness. For this reason, it is important to study and analyze the characteristics of their activity in order to select appropriate preventive exercises. METHODS: 10 clarinetists, who were experiencing joint pain due to instrumental practice, followed a specific program of physical activity, 3 times a week for 2 months. To assess postural changes after its implementation, the Langlade test and muscle pain scale were used at the beginning and the end of the program. RESULTS: The results show a significant decrease in perceived pain (p<0.001) and changes in the dorsal spine (p=0.001). Given the relationship between the improvement in the Langlade item, which refers to the correct position of the shoulder blades, and muscle pain, with a correlation level of 0.582, it can be said that a change in the shoulder girdle position leads to a decrease of pain in that area. CONCLUSIONS: In this pilot study of 10 clarinetists, a regular program of physical activity for 9 weeks led to an observable change in posture and a reduction in pain using self-report measures.


2019 ◽  
Vol 11 (3) ◽  
pp. 317-325 ◽  
Author(s):  
Tamar Kugler ◽  
Bohan Ye ◽  
Daphna Motro ◽  
Charles N. Noussair

We report three studies exploring the relationship between disgust and trust. Study 1a measured emotions using face-reading technology while participants played a repeated trust game. We observed a negative correlation between trust and disgust. Study 1b employed self-reports along with the face reader. The self-report procedure adversely affected participants’ emotional state and eliminated the correlation between trust and other emotions. Study 2 induced incidental disgust or sadness using virtual reality and manipulated participants’ awareness of the source of their emotions. Disgusted participants judged others as less trustworthy and sent less in a trust game than sad or control participants. An interaction indicated that awareness of the source of emotions eliminated the effect. Our data are consistent with the association between disgust and harsher moral judgments and suggest that disgust is antithetical to the building of trust. However, the association disappears if individuals are aware that their disgust is unrelated to the setting.


2007 ◽  
Vol 104 (3) ◽  
pp. 823-843 ◽  
Author(s):  
Laura P. McAvinue ◽  
Ian H. Robertson

The relationship between visual and motor imagery was investigated by administering a battery of visual and motor imagery measures to a sample of 101 men ( n = 49) and women ( n = 52), who ranged in age from 18 to 59 ( M=34.5, SD=12.6). A principal components analysis applied to the correlation matrix indicated four underlying components, which explained 62.9% of the variance. The components were named Implicit Visual Imagery Ability, Self-report of Visual and Motor Imagery, Implicit Motor Imagery Ability, and Explicit Motor Imagery Ability. These results suggested a dissociation between visual and motor imagery although visual and motor imagery were associated as self-reports and there were correlations among particular measures.


2012 ◽  
Vol 43 (4) ◽  
pp. 781-787 ◽  
Author(s):  
P. M. Gromann ◽  
F. A. Goossens ◽  
T. Olthof ◽  
J. Pronk ◽  
L. Krabbendam

BackgroundBullying victimization may be linked to psychosis but only self-report measures of victimization have been used so far. This study aimed (a) to investigate the differential associations of peer-nominated versus self-reported victim status with non-clinical psychotic experiences in a sample of young adolescents, and (b) to examine whether different types of self-reported victimization predict non-clinical psychotic experiences in these adolescents.MethodA combination of standard self-report and peer nomination procedures was used to assess victimization. The sample (n = 724) was divided into four groups (exclusively self-reported victims, self- and peer-reported victims, exclusively peer-reported victims, and non-victims) to test for a group effect on non-clinical psychotic experiences. The relationship between types of victimization and non-clinical psychotic experiences was examined by a regression analysis.ResultsSelf-reported victims, along with self- and peer-reported victims, scored higher than peer-reported victims and non-victims on non-clinical psychotic experiences. Self-reports of direct relational, indirect relational and physical victimization significantly improved the prediction of non-clinical psychotic experiences whereas verbal and possession-directed victimization had no significant predictive value.ConclusionsThe relationship between victimization and non-clinical psychotic experiences is only present for self-reported victimization, possibly indicative of an interpretation bias. The observed discrepancy between self-report and peer-report highlights the importance of implementing a combination of both measures for future research.


1988 ◽  
Vol 66 (1) ◽  
pp. 131-137 ◽  
Author(s):  
Mary A. Fristad

This study focused on social desirability in family members' self-reports. 32 clinical families (93 family members) were given self-report measures from the McMaster and Circumplex family-assessment models and a measure of social desirability. Clinicians assessed these families on clinical rating scales from the same models. Regression analyses were used to examine the relationship between self-reports, social desirability scores, and clinicians' ratings. It was expected that social desirability would be a suppressor variable (i.e., when accounted for, the similarity between clinicians' and family members' ratings would be enhanced). This did not occur; instead, social desirability was significantly but negatively correlated with ratings of pathology. Results provide evidence that correcting for social desirability on clinical pencil-and-paper tests is not supported.


2019 ◽  
Vol 28 (2) ◽  
pp. 274-284 ◽  
Author(s):  
Elizabeth Convery ◽  
Gitte Keidser ◽  
Louise Hickson ◽  
Carly Meyer

Purpose Hearing loss self-management refers to the knowledge and skills people use to manage the effects of hearing loss on all aspects of their daily lives. The purpose of this study was to investigate the relationship between self-reported hearing loss self-management and hearing aid benefit and satisfaction. Method Thirty-seven adults with hearing loss, all of whom were current users of bilateral hearing aids, participated in this observational study. The participants completed self-report inventories probing their hearing loss self-management and hearing aid benefit and satisfaction. Correlation analysis was used to investigate the relationship between individual domains of hearing loss self-management and hearing aid benefit and satisfaction. Results Participants who reported better self-management of the effects of their hearing loss on their emotional well-being and social participation were more likely to report less aided listening difficulty in noisy and reverberant environments and greater satisfaction with the effect of their hearing aids on their self-image. Participants who reported better self-management in the areas of adhering to treatment, participating in shared decision making, accessing services and resources, attending appointments, and monitoring for changes in their hearing and functional status were more likely to report greater satisfaction with the sound quality and performance of their hearing aids. Conclusion Study findings highlight the potential for using information about a patient's hearing loss self-management in different domains as part of clinical decision making and management planning.


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