Assessment of systemic and carcinogenic health risks of persistent organochlorine pesticide residues in four fruit vegetables in south-western Nigeria

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Gideon Oluwasogo Odewale ◽  
Mosudi Babatunde Sosan ◽  
John Adekunle Oyedele Oyekunle ◽  
Adeoluwa Oluwaseyi Adeleye
Keyword(s):  
Health Risk ◽  
Health Risks ◽  
Pesticide Residues ◽  
Risk Index ◽  
Daily Intake ◽  
Heptachlor Epoxide ◽  
Potential Health ◽  
Content Type ◽  
Endosulfan Sulphate ◽  
Systemic Health

PurposeThe study assessed the levels of organochlorine pesticides (OCPs) and their potential non-carcinogenic and carcinogenic health risks in four regularly consumed fruit vegetables.Design/methodology/approachThe OCPs’ residues were quantified using a gas chromatograph coupled with an electron capture detector (GC-ECD) and the dietary exposure of children, and adult consumers to the detected OCPs was evaluated using carcinogenic and systemic health risk estimations.FindingsAldrin, endrin, endrin aldehyde, a-endosulfan, β-endosulfan, endosulfan sulphate, heptachlor, heptachlor epoxide and dieldrin were detected in the four fruit vegetables. The predominant OCP residue in carrot, cucumber, tomatoes and watermelon was endosulfan sulphate with mean concentrations of 2.532 mg kg−1, 1.729 mg kg−1, 2.363 mg kg−1 and 1.154 mg kg−1, respectively. The residues levels in some of the fruit vegetables were higher than their respective maximum residue levels (MRLs) of 0.01–0.05 mg kg−1 set by the European Commission with concentrations above MRLs ranging between 25.5% and 100%. The systemic health risk estimations showed that the hazard index (HI) values for carrot (3.20), cucumber (9.25), tomatoes (50.21) and watermelon (16.76) were >1 for children consumers and the respective HI values of 2.87, 15.57 and 5.20 for adult consumers of cucumber, tomatoes and watermelon were >1 which implies potential systemic health risks. Four carcinogens (aldrin, dieldrin, heptachlor and heptachlor epoxide) had cancer risk index values greater than the acceptable risk of 1 in 1 million for both adult and children consumers.Originality/valueThe paper shows that despite the ban on the use of OCPs in Nigeria, they are still being used for agricultural production especially on some locally produced and regularly consumed fruit vegetables as reported in the present study. The non-existence of surveillance programmes on pesticide usage and the lack of proper monitoring of pesticide residues in food products including fruit and vegetables must have contributed to the levels of the detected OCP in the samples analysed. The current daily intake of OCP via contaminated vegetables may pose potential health risks to both the children and adult consumers of the fruit vegetables.

scholarly journals Study of nitrate levels in fruits and vegetables to assess the potential health risks in Bangladesh

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Rayhan Uddin ◽  
Mostak Uddin Thakur ◽  
Mohammad Zia Uddin ◽  
G. M. Rabiul Islam
Keyword(s):  
Cluster Analysis ◽  
Health Risks ◽  
Fruits And Vegetables ◽  
Risk Index ◽  
Daily Intake ◽  
Point Estimate ◽  
Nitrate Content ◽  
Nitrate Accumulation ◽  
Health Risk Index ◽  
Potential Health

AbstractNitrate is a chemical compound naturally present in fruits and vegetables. This study aims at assessing the nitrate levels and health risks arising from high consumption of fruits and vegetables in Bangladesh. Sixteen species of fruits and vegetables were examined for nitrates using High-Performance Liquid Chromatography with Photo Diode Array (PDA) detector. Ward’s hierarchical cluster analysis was carried out to identify the cluster of tested fruits and vegetables for the nitrate contents. A point estimate of the daily intake was applied to find the health risks that arise due to elevated levels of nitrate in fruits and vegetables. The results show that root and tuber vegetables accumulate significantly higher levels of nitrate in comparison to fruits and fruit vegetables (P < 0.05). In cluster analysis, the nitrate accumulation of fruits and vegetables show four clear clusters contributing to 29.54%, 7.17%, 4.42%, and 58.57% of the total nitrate content in the entire sample. The risk assessment of the Estimated Daily Intake (EDI) and Health Risk Index (HRI) of almost all the tested samples was in the acceptable range, except for radish, thereby indicating the acceptance of risk due to nitrate intake in Bangladesh. As nitrate may have had risk factor for health, during cultivation and storing the product should be properly monitored.

scholarly journals Heavy metals uptake by the global economic crop (Pisum sativum L.) grown in contaminated soils and its associated health risks

PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0252229
Author(s):  
Tarek M. Galal ◽  
Loutfy M. Hassan ◽  
Dalia A. Ahmed ◽  
Saad A. M. Alamri ◽  
Sulaiman A. Alrumman ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Pisum Sativum ◽  
Health Risks ◽  
Contaminated Soils ◽  
Risk Index ◽  
Daily Intake ◽  
High Concentration ◽  
Health Risk Index ◽  
Potential Health ◽  
Polluted Sites

The aim of the present investigation was to determine the concentration of heavy metals in the different organs of Pisum sativum L. (garden pea) grown in contaminated soils in comparison to nonpolluted soils in the South Cairo and Giza provinces, Egypt, and their effect on consumers’ health. To collect soil and plant samples from two nonpolluted and two polluted farms, five quadrats, each of 1 m2, were collected per each farm and used for growth measurement and chemical analysis. The daily intake of metals (DIM) and its associated health risks (health risk index (HRI) were also assessed. The investigated heavy metals were cadmium (Cd), arsenic (As), chromium (Cr), copper (Cu), nickel (Ni), iron (Fe), manganese (Mn), zinc (Zn), silver (Ag), cobalt (Co) and vanadium (V). Significant differences in soil heavy metals, except As, between nonpolluted and polluted sites were recorded. Fresh and dry phytomass, photosynthetic pigments, fruit production, and organic and inorganic nutrients were reduced in the polluted sites, where there was a high concentration of heavy metals in the fruit. The bioaccumulation factor for all studied heavy metals exceeded 1 in the polluted sites and only Pb, Cu and Mn exceeded 1 in the nonpolluted sites. Except for Fe, the DIM of the studied heavy metals in both sites did not exceed 1 in either children or adults. However, the HRI of Pb, Cd, Fe, and Mn in the polluted plants and Pb in the nonpolluted ones exceeded 1, indicating significant potential health risks to consumers. The authors recommend not to eat garden peas grown in the polluted sites, and farmers should carefully grow heavy metals non-accumulating food crops or non-edible plants for other purposes such as animal forages.

scholarly journals Diazinon Residues in Rice and Associated Health Risks for Human; A Case Study in Rasht, Iran

2021 ◽  
Vol 9 (2) ◽  
pp. 169-176
Author(s):  
Fatemeh Ghanbari ◽  
◽  
Maryam Kiani Sadr ◽  
Masoud Kouckakian ◽  
Kobra Melhosseini Darani ◽  
...  
Keyword(s):  
Health Risk ◽  
Health Risks ◽  
Organophosphorus Pesticides ◽  
Risk Index ◽  
Paddy Fields ◽  
Agricultural Crop ◽  
Northern Iran ◽  
Health Risk Index ◽  
Potential Health ◽  
Rice Consumption

Background: Rice is the most important agricultural crop and the main food in Gilan and Mazandaran Provinces in northern Iran where organophosphorus pesticides, especially diazinon, are used. The excessive use of this insecticide in the paddy fields of Rasht County is a serious threat to people’s health. Methods: In this study, 30 rice samples were collected from five zones in the paddy fields of Rasht in summer. The samples were analyzed when rice is sold to assess the health risk caused by diazinon residues in rice. Following the digestion process, the samples were injected into a High-Performance Liquid Chromatography (HPLC) instrument. Analysis of Variance (ANOVA) and one-sample t-test were respectively used for analyzing data and the Health Risk Index (HRI) for assessing the risk of rice consumption. Results: According to the results, the mean residual diazinon concentration in the rice crops of the five studied zones at the time of consumption (three months after harvest) was 0.4±0.43 mg/kg-1. This was higher than the Iranian standard for permissible diazinon concentration in rice. The results of the health risk assessment for rice consumption indicated an HRI value of 0.13 for rice consumption, which did not constitute a serious risk for people who consume rice regularly. Conclusion: Although the results of this study showed that there are no potential health risks for consumers, with increasing the use of chemical pesticides for crops, to achieve food safety, regular monitoring of pesticide residues in crops is recommended

scholarly journals RetractedHuman Health Risk of Chromium Intake From Consumption of Poultry Meat and Eggs in Dhaka, Bangladesh

2017 ◽  
Vol 7 (14) ◽  
pp. 30-36 ◽  
Author(s):  
Md. Shakhaoat Hossain ◽  
Prantik Roy ◽  
Monira Islam ◽  
Md. Alamgir Zaman Chowdhury ◽  
Zeenath Fardous ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Health Risk ◽  
Human Health ◽  
Health Risks ◽  
Daily Intake ◽  
Poultry Meat ◽  
Poultry Feed ◽  
Potential Health ◽  
Meat And Eggs ◽  
Target Hazard Quotients

Background. Heavy metals contamination of food is a serious threat. Long term exposure may lead to human health risks. Poultry and eggs are a major source of protein, but if contaminated by heavy metals, have the potential to lead to detrimental effects on human health. Objectives. The objective of this study is to determine chromium concentrations in poultry meat (flesh and liver) and eggs collected from poultry farms in Dhaka, Bangladesh, to calculate the daily intake of chromium from the consumption of poultry meat and eggs for adults, and to evaluate their potential health risk by calculating the target hazard quotients (THQ). Methods. All samples of poultry feed, meat (flesh and liver) and eggs were analyzed by a graphite furnace atomic absorption spectrometer (AAS) (GFA- EX- 7i Shimadju, Japan). Results. Chromium concentrations were recorded in the range of not detected (ND) to 1.3926±0.0010 mg kg−1 and 0.0678±0.0001 mg kg−1 to 1.3764±0.0009 mg kg−1 in the liver of broiler and layer chickens, respectively. Chromium concentrations were determined in the range of 0.069±1.0004 mgkg−1 to 2.0746±0.0021 mg kg−1 and 0.0362±0.0002 mg kg−1 to 1.2752±0.0014 mg kg−1 in the flesh of broiler and layer chicken, respectively. The mean concentration of chromium in eggs was 0.2174−1.08 mg kg.−1 The highest concentration of chromium 2.4196±0.0019 mg kg−1 was found in egg yolk. Target hazard quotients values in all poultry flesh, liver and eggs samples were less than one, indicating no potential health risks to consumers. Conclusions. The estimated daily intake values of chromium were below the threshold limit. Thus, our results indicate that no adverse health effects are expected as a resultof ingestion of chicken fed with tannery waste. Competing Interests. The authors declare no competing financial interests. Ethics Approval: This study was approved by the Biosafety, Biosecurity & Ethical Committee of Jahangirnagar University.

scholarly journals Health Risk Assessment and Determination of Some Heavy Metals in Commonly Consumed Traditional Herbal Preparations in Northeast Ethiopia

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Mihreteab Meseret ◽  
Gebremariam Ketema ◽  
Haile Kassahun
Keyword(s):  
Heavy Metals ◽  
Health Risk ◽  
Health Risks ◽  
Microwave Plasma ◽  
Daily Intake ◽  
Permissible Limit ◽  
Potential Health ◽  
Herbal Preparations ◽  
Northeast Ethiopia

Background. Most traditional medicines were prepared from plant origins. These plants could be contaminated by heavy metals, pesticides, and/or toxins. Therefore, the aim of the present study was to determine the level of heavy metals such as lead (Pb), cadmium (Cd), chromium (Cr), and copper (Cu) in frequently used traditional herbal preparations sold in Northeast Ethiopia and to estimate their health risks associated with their daily intake. Methods. A total of 6 traditional herbal preparations were randomly collected from local herbal shops of Dessie and Kombolcha town, Northeast Ethiopia. The samples were prepared for analysis by wet digestion method using nitric acid and hydrochloric acid treatment. The accuracy of the method was analyzed by the spike recovery test. Determination of Pb, Cd, Cr, and Cu by microwave plasma atomic emission spectroscopy was made in herbal preparations traditionally used in Dessie and Kombolcha town, Northeast Ethiopia. By calculating estimated daily intake (EDI), hazard quotients (HQ), and Hazard Index (HI) of metals, the health risk associated with the consumption of the analyzed herbal preparations was also evaluated. Results. The levels of heavy metals were in the range of 3.0–3.92 mg/kg for Pb, 5.35–10.7 mg/kg for Cr, and 0.815–12.3 mg/kg for Cu. However, cadmium was not detected in any of the traditional herbal preparations. This study revealed that the level of Pb and Cu in all analyzed samples was within the WHO maximum permissible limit of 10 mg/kg and 40 mg/kg, respectively. The level of Cr in all traditional herbal preparations was beyond the WHO maximum permissible limit (2 mg/kg). From the health point of view, the HQ value of Cr for KD-03 and KD-04 is greater than 1, suggesting potential health risk. Furthermore, the HI value had revealed that the consumption of KD-02, KD-03, and KD-04 samples had the potential of posing health risks to consumers over long-term consumption of herbal preparations. Conclusion. This study showed that most of the metal concentration levels in the herbal products were within the WHO maximum permissible limits. However, all samples had Cr levels above the WHO maximum permissible limit. Based on the results of this study, there would be a noncarcinogenic health risk to the consumer associated with the consumption of some herbal preparations marketed in Northeast Ethiopia.

scholarly journals Puplic Health Implications of Pesticide Residues in Irish Potatoes (Solanum tuberosum) from Jos Nigeria

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 259-259
Author(s):  
Grace Taiwo Otitoju ◽  
Olawale Otitoju
Keyword(s):  
Public Health ◽  
Food Safety ◽  
Health Risk ◽  
Pesticide Residues ◽  
Risk Index ◽  
Residue Analysis ◽  
Daily Intake ◽  
Health Concern ◽  
Central Research ◽  
Health Risk Index

Abstract Objectives There is a growing public health concern on the indiscriminate use of pesticides in agriculture among farmers from developing countries including Nigeria. The presence of pesticide residues in food samples may pose a deleterious effect on food safety and consequently compromise the health of consumers especially children, elderly, and pregnant women. The estimation of pesticides residues via dietary intake constitutes a vital integral part of regulatory processes that seeks to preserve public health. This study is therefore focused on the estimation of some pesticide residues in samples of Irish potatoes collected from Jos Nigeria. Methods The samples were collected from five different markets in Jos Plateau State Nigeria. All the samples were transported to the Central Research Laboratory, Ilorin, Nigeria. The pesticide residue analysis was carried out using GC/MS after sample extraction, filtration and Concentration. After the analysis was carried out, the result obtained were subjected to statistical analysis using SPSS (Statistical Package for Social Sciences) statistical software (version 21) after which the Mean, Standard deviations and ANOVA (Analysis of variance) were calculated. Results The result shows that 17 different pesticide residues were identified with ten (10) organochlorines, two (2) organophosphates, one (1) thiocarbamate, one (1) benzamide and two (2) of them were unclassified. The concentration of these pesticides were determined which was then used to determine the estimated daily intake. The ADI and MRL for each pesticide was sought for and the health risk was also evaluated. With the results obtained, it was noticed that most of these pesticides usually exceed their ADI and MRL which then makes them hazardous to the human health. Considering the health risk index of consumers Aldrin, Heptachlor, Mecarbem and Dieldrin proved to be very hazardous (P &gt; 1). Conclusions These pesticides can cause harmful effects on the food commodities which ultimately cause a damaging impact on the health of human. To guarantee food safety, continuous monitoring is recommended for pesticide residues in Irish potatoes. Funding Sources Self-sponsored.

scholarly journals Bioaccumulation of Antimony and Arsenic in Vegetables and Health Risk Assessment in the Superlarge Antimony-Mining Area, China

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Defang Zeng ◽  
Saijun Zhou ◽  
Bozhi Ren ◽  
Tengshu Chen
Keyword(s):  
Risk Assessment ◽  
Health Risk ◽  
Health Risk Assessment ◽  
Health Risks ◽  
Hazard Quotient ◽  
Daily Intake ◽  
Mining Area ◽  
Coriandrum Sativum ◽  
Potential Health ◽  
Safe Limit

Heavy metal pollution in soils caused by mining and smelting has attracted worldwide attention for its potential health risks to residents. This paper studies the concentrations and accumulations of Sb and As in both soils and vegetables and the human health risks of Sb and As in vegetables from Xikuangshan (XKS) Sb mine, Hunan, China. Results showed that the soils were severely polluted by Sb and As; Sb and As have significant positive correlation. Sb and As concentrations in vegetables were quite different:Coriandrum sativumL. was the highest in Sb,Allium fistulosumL. was the highest in As, andBrassica pekinensisL. was the lowest in both Sb and As;Daucus carotaL. andCoriandrum sativumL. showed advantage in accumulating Sb and As;Coriandrum sativumL. had higher capacity of redistributing Sb and As within the plant. Health risk assessment results showed that the hazard quotient (HQ) values of Sb and As in vegetables were in the ranges of 1.61–3.33 and 0.09–0.39, respectively; the chronic daily intake (CDI) and hazard quotient (HQ) values of Sb were over the safe limit recommended by FAO and WHO, indicating that long-term consumption of vegetables from the surrounding soils of XKS mine may bring health risks to residents.

scholarly journals Human Health Risk Surveillance of Organochlorine Pesticides in River Water and Fishes from Bangladesh

2021 ◽  
Vol 14 (4) ◽  
pp. 1777-1785
Author(s):  
G. M. M. Anwarul Hasan
Keyword(s):  
Health Risk ◽  
Human Health ◽  
River Water ◽  
Organochlorine Pesticides ◽  
Health Risks ◽  
Risk Index ◽  
Human Health Risk ◽  
Sample Collection ◽  
Potential Health ◽  
Fish Samples

Organochlorine pesticides (OCPs) are chlorinated hydrocarbons that used extensively in the last century for agricultural purposes. Excess use of OCPs results pesticide residues accumulation in the water and fishes and causes various health problems. The concentrations of Organochlorine pesticides (OCPs) residues in water and fish samples of six most contaminated rivers surrounding Dhaka, Bangladesh namely Buriganga, Turag, Balu, Sitalakhya, Bangshai and Dhaleswari were determined and assessed the possible health risks through consumption of accumulated OCPs in fishes from those rivers. .As we know, OCPs are non-biodegradable and thus remain in the environment as pollutants. Therefore, OCPs exposure must be monitored and controlled to reduce the human health risks. Risk assessment is an important procedure to quantify the potential health risks and provides information the risk managers to control the overuse of OCPs. The concentrations of OCPs residues were determined by Gas Chromatography tandem Mass Spectrometry (GC-MS/MS). After sample collection, sample was extracted and analyzed according to the validated method. Several OCPs residues including Aldrin, p,p-DDE, Eldrine ketone, p,p-DDD, Endrin, α-Endosulfan, Heptachlorepoxide, p,p-DDT, Endosulfan sulfate and β-Endosulfan were detected in river water and residues including Aldrin, p,p-DDE, Heptachlorepoxide, p,p-DDD, Endrin and p,p-DDT were detected in fish samples. The Health risk index (HI) values of Aldrin, p,p-DDE, Heptachlorepoxide, p,p-DDD, Endrin and p,p-DDT from analyzed three fish species (Acanthobrama microlepis, Barbonymus gonionotus and Batasio tengana) were ranged from 0.036 to 1.696, 0.029 to 2.007, 0.022 to 1.117, 0.0231 to 0.721, 0.019 to 1.597 and 0.019 to 1.205 for Buriganga, Turag, Balu, Sitalakhya, Bangshai and Dhaleswari rivers respectively. OCPs are quantified in river water and fish samples and potential health risks are accessed. This study suggested that, there might have OCPs mediated health risks through long term exposure of OCPs residues from fishes of those polluted rivers. Although, our study provided estimation about the presence of OCPs in water and fishes from six contaminated rivers surrounding Dhaka city but, further studies are suggested to ensure the safety of peoples.

scholarly journals Transfer of heavy metals to leafy vegetables in Gazipur textile area

2021 ◽  
Vol 56 (3) ◽  
pp. 155-164
Author(s):  
M Begum ◽  
MN Gani ◽  
MD Alam
Keyword(s):  
Heavy Metals ◽  
Health Risk ◽  
Contaminated Soils ◽  
Risk Index ◽  
Daily Intake ◽  
Leafy Vegetables ◽  
Health Risk Index ◽  
Potential Health ◽  
Mean Concentration ◽  
Significant Health

Heavy metal pollution of soils is a major concern today because contamination of food chain considered as one of the major environmental pathways of human exposure leading to potential health risk.A pot experiment was carried out to investigate the transfer of Zn, Cu, Ni, Fe, Cd, Cr, Pb and Mn from non-contaminated and contaminated soils to jute leaves vegetable plant and to evaluate their associated health risk in the local population.The mean concentration of the heavy metals in jute leaves vegetable plants followed a decreasing order of Fe>Zn>Mn>Cu>Cr>Pb>Cd>Ni. Among the all heavy metals the highest transfer factor (TF) values was found for Cu (77.50-34.95) and the lowest TF value was observed for Ni(0-0.001) in jute leaves vegetables plant. The daily intake of metals (DIM) for a person through ingestion of jute leaves were in order of Fe>Mn>Zn>Cu>Cr>Pb>Ni>Cd. The values of health risk index (HRI) for the heavy metals were less than 1, therefore, no significant health risk is anticipated for the local consumers through ingestion of jute leaves. Bangladesh J. Sci. Ind. Res.56(3), 155-164, 2021

Distributions and risks of Cu, Cd, Pb and Zn in soils and rice in the North River Basin, South China

2018 ◽  
Vol 109 (3-4) ◽  
pp. 483-493
Author(s):  
Jing BAI ◽  
Wenyan LI ◽  
Yulong ZHANG ◽  
Ling XIAO ◽  
Weisheng LU ◽  
...  
Keyword(s):  
Health Risk ◽  
Health Risks ◽  
Risk Index ◽  
High Mobility ◽  
Pollution Index ◽  
Health Risk Index ◽  
Potential Health ◽  
The North ◽  
Risk Indices ◽  
Almost All

ABSTRACTAs the largest industrial and population centre in China, the Pearl River Delta is facing a growing threat of heavy metal pollution from local mining and power industries. This study investigates the distribution and potential health risks of copper (Cu), cadmium (Cd), lead (Pb) and zinc (Zn) in paddy soils and rice at four typical sites. The Nemerow synthetic pollution index (PN) of soils from Fogang, Dabao Mountain, Shaoguan and Lechang were 8.40, 9.10, 4.64 and 10.28, respectively, indicating serious pollution at all four sampling sites. The average concentrations of Cu, Cd, Pb and Zn in rice grains were 2.23, 10.98, 29.84 and 1.62 times their corresponding maximum allowable levels, indicating potential health risks to humans. Cd has greater bioavailability because of its high mobility from soil to roots, and its subsequent transfer to grains. Pb mainly accumulates in roots because of its lower translocation rate from roots to grains. The greatest health risk index for Cd and Pb for adults and children was at the Shaoguan site, probably due to pollution from atmospheric deposition. Cd and Pb had greater health risk indices than Cu and Zn at almost all sites, indicating a major health risk to local people.

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