China will pay high price for regulating vehicle data

2021 ◽  
Keyword(s):  
High Price ◽  
Vehicle Performance ◽  
Content Type ◽  
Related Data ◽  
Vehicle Data ◽  
Potential Applications ◽  
Near Future ◽  
Data Centres ◽  
Potential Use ◽  
Do So

Significance These data have broader potential applications, from monitoring vehicle performance in order to enable future improvements, to surveilling drivers or the environment in which they drive. In China, this has led to growing concerns about the potential use of vehicle-sourced data. Impacts Foreign carmakers that have not yet opened data centres in China will need to do so in the near future. The new regulations may disadvantage the development of Chinese AV firms. The regulations could have a major impact beyond China as a leading example or model for vehicle-related data protection.

scholarly journals Dashboard design and the ‘datafied’ driving experience

2021 ◽  
Vol 8 (2) ◽  
pp. 205395172110498
Author(s):  
Sam Hind
Keyword(s):  
Automotive Industry ◽  
Navigation System ◽  
Natural Speech ◽  
Navigation Systems ◽  
Design Decisions ◽  
Driving Experience ◽  
Related Data ◽  
Strategic Design ◽  
Vehicle Data ◽  
Do So

In this article, I consider how the redesign of vehicle dashboards has restructured car-related data processes. I do so by charting the emergence of two such processes enabled by the redesign of vehicle dashboards: firstly, the transformation of ‘geodata’ into ‘navigational data’ with the integration of voice-activated navigation systems into vehicle dashboards, and secondly, the transformation of ‘vehicle data’ into ‘driving data’ in the convergence, and customization, of dashboard features and functionality. Both transformations are enabled through strategic design decisions, persuading drivers to participate in novel practices they might otherwise not. Firstly, in that voice-activation is depicted as a seamless, unmediated interface between the normal, natural speech of a driver, and the vehicle itself. Secondly, through the strategy of control, the driver is persuaded to believe they have full(er) customizable power within, and of, Firstly, in that voice-activation is depicted as a seamless, unmediated interface between the normal, natural speech of a driver, and the vehicle itself. Secondly, through the strategy of control, the driver is persuaded to believe they have full(er) customizable power within, and of, the vehicle. The systems discussed here – a voice-activated navigation system built on the What3words platform, and a ‘widescreen’ dashboard in a range of Mercedes-Benz vehicles – are representative of broader efforts within the automotive industry to cultivate a newly ‘datafied’ driving experience.

Humanoid robots from the past to the present

2020 ◽  
Vol 47 (4) ◽  
pp. 465-472 ◽  
Author(s):  
Robert Bogue
Keyword(s):  
Disaster Response ◽  
Humanoid Robots ◽  
Power Sources ◽  
Content Type ◽  
Recent Developments ◽  
Potential Applications ◽  
Technical Details ◽  
Heavy Loads ◽  
Near Future ◽  
Application Specific

Purpose This paper aims to provide technical details of humanoid robot developments from the 1970s to the present day and to consider their potential applications and prospects. Design/methodology/approach Following an introduction, this first identifies the motivations for developing humanoid robots. It then provides a technical review of developments conducted between the 1970s and the late 2010s. The most recent developments and their applications are then discussed and the paper concludes with a brief consideration of future prospects. Findings Since the first efforts to develop humanoid robots in Japan, the 1970s, the technology has attracted global interest and progress has been dramatic. Enabled by developments in computing, imaging, sensing, power sources, actuators and other technologies, today’s humanoid robots are agile, stable and capable of all manner of human-like capabilities such as running, climbing stairs and carrying heavy loads. Real-world uses in fields such as construction, assembly, disaster response and home assistance are expected to emerge in the near future as a result of application-specific developments. Originality/value This illustrates the technological evolution of humanoid robots from their inception in the 1970s to the present day.

Nano sensors: Designing and Fabrication, Applications for flexible devices and Future Perspectives

2020 ◽  
Vol 16 ◽  
Author(s):  
Muhammad Bilal Tahir ◽  
Aleena Shoukat ◽  
Tahir Iqbal ◽  
Asma Ayub ◽  
Saff-e Awal ◽  
...  
Keyword(s):  
Self Assembly ◽  
Multidisciplinary Approach ◽  
Future Perspectives ◽  
Flexible Devices ◽  
More Care ◽  
Potential Applications ◽  
Nano Sensors ◽  
Mechanical Sensor ◽  
Small Models ◽  
Near Future

: The field of nanosensors has been gaining a lot of attention due to its properties such as mechanical and electrical ever since its first discovery by Dr. Wolter and first mechanical sensor in 1994. The rapidly growing demand of nanosensors has become profitable for a multidisciplinary approach in designing and fabrication of materials and strategies for potential applications. Frequent stimulating advancements are being suggested and established in recent years and thus heading towards multiple applications including food safety, healthcare, environmental monitoring, and biomedical research. Nanofabrication being an efficient method has been used in different industries like medical pharmaceutical for their complex functional geometry at a lower scale. These nanofabrications apply through different methods. There are five most commonly known methods which are frequently used, including top-down lithography, molecular self-assembly, bottom-up assembly, heat and pull method for fabrication of biosensors, etching for fabrication of nanosensors etc. Nanofabrication help at the nanoscale to design and work with small models. But these models due to their small size and being sensitive need more care for use as well as more training and experience to do work with. All methods used for nanofabrication are good and helpful. But more preferred is molecular self-assembly as it is helpful in mass production. Nanofabrication has become an emerging and developing field and it assumed that in near future our world is known by the new devices of nanofabrication.

scholarly journals In VitroActivities of Hexaazatrinaphthylenes against Leishmania spp.

2015 ◽  
Vol 59 (5) ◽  
pp. 2867-2874 ◽  
Author(s):  
Atteneri López-Arencibia ◽  
Daniel García-Velázquez ◽  
Carmen M. Martín-Navarro ◽  
Ines Sifaoui ◽  
María Reyes-Batlle ◽  
...  
Keyword(s):  
Therapeutic Agents ◽  
Content Type ◽  
Inhibition Effect ◽  
Intracellular Amastigotes ◽  
Dependent Inhibition ◽  
Leishmania Spp ◽  
Dose Dependent Inhibition ◽  
Dose Dependent ◽  
Potential Use

ABSTRACTThein vitroactivity of a novel group of compounds, hexaazatrinaphthylene derivatives, against two species ofLeishmaniais described in this study. These compounds showed a significant dose-dependent inhibition effect on the proliferation of the parasites, with 50% inhibitory concentrations (IC50s) ranging from 1.23 to 25.05 μM against the promastigote stage and 0.5 to 0.7 μM against intracellular amastigotes. Also, a cytotoxicity assay was carried out to in order to evaluate the possible toxic effects of these compounds. Moreover, different assays were performed to determine the type of cell death induced after incubation with these compounds. The obtained results highlight the potential use of hexaazatrinaphthylene derivatives againstLeishmaniaspecies, and further studies should be undertaken to establish them as novel leishmanicidal therapeutic agents.

scholarly journals Decline in Marriage Associated with the COVID-19 Pandemic in the United States

2020 ◽  
Vol 6 ◽  
pp. 237802312098032
Author(s):  
Brandon G. Wagner ◽  
Kate H. Choi ◽  
Philip N. Cohen
Keyword(s):  
United States ◽  
The United States ◽  
Cumulative Number ◽  
Short Term ◽  
Know How ◽  
The Social ◽  
Reporting Delays ◽  
Social Upheaval ◽  
Near Future ◽  
Do So

In the social upheaval arising from the coronavirus disease 2019 (COVID-19) pandemic, we do not yet know how union formation, particularly marriage, has been affected. Using administration records—marriage certificates and applications—gathered from settings representing a variety of COVID-19 experiences in the United States, the authors compare counts of recorded marriages in 2020 against those from the same period in 2019. There is a dramatic decrease in year-to-date cumulative marriages in 2020 compared with 2019 in each case. Similar patterns are observed for the Seattle metropolitan area when analyzing the cumulative number of marriage applications, a leading indicator of marriages in the near future. Year-to-date declines in marriage are unlikely to be due solely to closure of government agencies that administer marriage certification or reporting delays. Together, these findings suggest that marriage has declined during the COVID-19 outbreak and may continue to do so, at least in the short term.

scholarly journals Monopoly behavior of China’s manufacturing enterprises

2019 ◽  
Vol 2 (1) ◽  
pp. 157-179
Author(s):  
Guidong Wang
Keyword(s):  
Design Methodology ◽  
Manufacturing Industry ◽  
Rent Seeking ◽  
Content Type ◽  
Manufacturing Enterprises ◽  
Slow Decline ◽  
State Capital ◽  
The Government ◽  
Do So ◽  
Initial Jump

Purpose With the increase of state capital, corporate total factor productivity (TFP) has a tendency to jump up at first and then slowly decrease. Generally, no significant “productivity paradox” can be observed in China’s manufacturing industry. With the increase of export density, corporate TFP also shows a trend of initial jump growth and subsequent slow decline. This paper aims to discuss these issues. Design/methodology/approach Using the 1996–2013 China Industrial Enterprise Database, this paper studies the monopolistic behavior of Chinese manufacturing enterprises through the measurement of TFP and corporate monopoly power. Findings Results show that China’s manufacturing monopoly enterprises are generally innovation-oriented rather than rent-seeking. However, there are certain differences between diversified types of monopoly enterprises: the ones with state capital are more inclined to innovate than those without, whereas the ones with export delivery value are more inclined to seek rent than those without. Originality/value Therefore, the government should implement differentiated policies for diversified types of monopoly enterprises, and do so in a targeted manner fully reflecting the containment of rent-seeking and the encouragement of innovation.

Thymidine kinase-mediated killing of rat brain tumors

1993 ◽  
Vol 79 (5) ◽  
pp. 729-735 ◽  
Author(s):  
David Barba ◽  
Joseph Hardin ◽  
Jasodhara Ray ◽  
Fred H. Gage
Keyword(s):  
Gene Therapy ◽  
Brain Tumors ◽  
Tumor Cells ◽  
Wild Type ◽  
Cns Disorders ◽  
Content Type ◽  
Potential Applications ◽  
Ganciclovir Treatment ◽  
The Brain ◽  
Fine Print

✓ Gene therapy has many potential applications in central nervous system (CNS) disorders, including the selective killing of tumor cells in the brain. A rat brain tumor model was used to test the herpes simplex virus (HSV)-thymidine kinase (TK) gene for its ability to selectively kill C6 and 9L tumor cells in the brain following systemic administration of the nucleoside analog ganciclovir. The HSV-TK gene was introduced in vitro into tumor cells (C6-TK and 9L-TK), then these modified tumor cells were evaluated for their sensitivity to cell killing by ganciclovir. In a dose-response assay, both C6-TK and 9L-TK cells were 100 times more sensitive to killing by ganciclovir (median lethal dose: C6-TK, 0.1 µg ganciclovir/ml; C6, 5.0 µg ganciclovir/ml) than unmodified wild-type tumor cells or cultured fibroblasts. In vivo studies confirmed the ability of intraperitoneal ganciclovir administration to kill established brain tumors in rats as quantified by both stereological assessment of brain tumor volumes and studies of animal survival over 90 days. Rats with brain tumors established by intracerebral injection of wild-type or HSV-TK modified tumor cells or by a combination of wild-type and HSV-TK-modified cells were studied with and without ganciclovir treatments. Stereological methods determined that ganciclovir treatment eliminated tumors composed of HSV-TK-modified cells while control tumors grew as expected (p < 0.001). In survival studies, all 10 rats with 9L-TK tumors treated with ganciclovir survived 90 days while all untreated rats died within 25 days. Curiously, tumors composed of combinations of 9L and 9L-TK cells could be eliminated by ganciclovir treatments even when only one-half of the tumor cells carried the HSV-TK gene. While not completely understood, this additional tumor cell killing appears to be both tumor selective and local in nature. It is concluded that HSV-TK gene therapy with ganciclovir treatment does selectively kill tumor cells in the brain and has many potential applications in CNS disorders, including the treatment of cancer.

Bankarization in the first European cities with an equal number of Muslim and Christian inhabitants

2017 ◽  
Vol 10 (4) ◽  
pp. 554-580
Author(s):  
Miguel Ángel Pérez-Castro ◽  
Miguel Ángel Montero-Alonso ◽  
Akram Abderrahman-Azaar
Keyword(s):  
North Coast ◽  
Content Type ◽  
European Cities ◽  
The North ◽  
Financial Depth ◽  
Financial Framework ◽  
European Banks ◽  
The Mean ◽  
Different Cultures ◽  
Near Future

Purpose This paper aims to analyze the situation of the financial system in the Spanish-governed cities of Melilla and Ceuta, Christian and Muslim cities located on the north coast of Africa, and compared it with the mean bankarization level in the rest of Spain in 2000-2015. Design/methodology/approach Although different calculation methods have been proposed, most authors agree that the bankarization level of a country or a territory reflects the development of the society as a whole and has a positive correlation with economic growth. The indicators of financial depth proposed by these researchers are not only the ratio between variables such as loans, deposits, etc., but also the ratios of these variables to the population and the gross domestic product (GDP) of the country or territory. Findings The results obtained revealed that there are differences between these two North African Spanish cities. Furthermore, the financing gap between the mean bankarization levels of these cities and those of mainland Spain was found to be even larger than most of the other economic indicators (GDP per capita and the unemployment rate). Practical implications The authors are convinced that the manuscript is a contribution of great interest for serving pilot experience in cities wishing to offer a development of traditional banking and Islamic banking. The paper should be of interest to readers in the areas of finance systems and commercial banks where two different cultures coexist. Originality/value This is the first research study on the financial framework of European cities whose populations have an approximately equal percentage of Christians and Muslims. The data reflected the existence of savings and loan methods parallel to conventional banking. The conclusion was that in the near future, it would be advisable for European banks to take into account the cultural customs and religious practices of potential Muslim clients.

scholarly journals The Novel Arylamidine T-2307 MaintainsIn VitroandIn VivoActivity against Echinocandin-Resistant Candida albicans

2014 ◽  
Vol 59 (2) ◽  
pp. 1341-1343 ◽  
Author(s):  
Nathan P. Wiederhold ◽  
Laura K. Najvar ◽  
Annette W. Fothergill ◽  
Rosie Bocanegra ◽  
Marcos Olivo ◽  
...  
Keyword(s):  
Body Weight ◽  
Candida Albicans ◽  
Invasive Candidiasis ◽  
Placebo Control ◽  
The Novel ◽  
Content Type ◽  
Fungal Burden ◽  
Potential Use

ABSTRACTWe evaluated thein vitroandin vivoactivities of the investigational arylamidine T-2307 against echinocandin-resistantCandida albicans. T-2307 demonstrated potentin vitroactivity, and daily subcutaneous doses between 0.75 and 6 mg/kg of body weight significantly improved survival and reduced fungal burden compared to placebo control and caspofungin (10 mg/kg/day) in mice with invasive candidiasis caused by an echinocandin-resistant strain. Thus, T-2307 may have potential use in the treatment of echinocandin-resistantC. albicansinfections.

Accessing offshoring advantages: what and how to offshore

2015 ◽  
Vol 8 (2/3) ◽  
pp. 262-283 ◽  
Author(s):  
Alona Mykhaylenko ◽  
Ágnes Motika ◽  
Brian Vejrum Waehrens ◽  
Dmitrij Slepniov
Keyword(s):  
Performance Outcomes ◽  
Offshore Outsourcing ◽  
Strategic Decisions ◽  
Content Type ◽  
Different Types ◽  
Captive Offshoring ◽  
Performance Results ◽  
Governance Modes ◽  
Different Levels ◽  
Do So

Purpose – The purpose of this paper is to advance the understanding of factors that affect offshoring performance results. To do so, this paper focuses on the access to location-specific advantages, rather than solely on the properties of the offshoring company, its strategy or environment. Assuming that different levels of synergy may exist between particular offshoring strategic decisions (choosing offshore outsourcing or captive offshoring and the type of function) and different offshoring advantages, this work advocates that the actual fact of realization of certain offshoring advantages (getting or not getting access to them) is a more reliable predictor of offshoring success. Design/methodology/approach – A set of hypotheses derived from the extant literature is tested on the data from a quantitative survey of 1,143 Scandinavian firms. Findings – The paper demonstrates that different governance modes and types of offshored function indeed provide different levels of access to different types of location-specific offshoring advantages. This difference may help to explain the ambiguity of offshoring initiatives performance results. Research limitations/implications – Limitations of the work include using only the offshoring strategy elements and only their limited variety as factors potentially influencing access to offshoring advantages. Also, the findings are limited to Scandinavian companies. Originality/value – The paper introduces a new concept of access, which can help to more reliably predict performance outcomes of offshoring initiatives. Recommendations are also provided to practitioners dealing with offshoring initiatives.

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