The relationship between moderate-to-vigorous intensity physical activity and insulin resistance, insulin-like growth factor (IGF-1)-system 1, leptin and weight change in healthy women during pregnancy and after delivery

2014 ◽  
Vol 82 (1) ◽  
pp. 68-75 ◽  
Author(s):  
Carla L. van der Wijden ◽  
Henriette A. Delemarre-van de Waal ◽  
Willem van Mechelen ◽  
Mireille N.M. van Poppel
Keyword(s):  
Physical Activity ◽  
Insulin Resistance ◽  
Growth Factor ◽  
Weight Change ◽  
Insulin Like Growth Factor ◽  
Healthy Women ◽  
Intensity Physical Activity ◽  
Vigorous Intensity ◽  
System 1 ◽  
The Relationship

Objectively Measured Age-Related Changes in the Intensity Distribution of Daily Physical Activity in Adults

2009 ◽  
Vol 6 (4) ◽  
pp. 419-425 ◽  
Author(s):  
Makoto Ayabe ◽  
Takuya Yahiro ◽  
Myumi Yoshioka ◽  
Hiroyuki Higuchi ◽  
Yasuki Higaki ◽  
...  
Keyword(s):  
Physical Activity ◽  
Light Intensity ◽  
Daily Physical Activity ◽  
Men And Women ◽  
Age Related ◽  
Intensity Physical Activity ◽  
Vigorous Intensity ◽  
Objectively Measured ◽  
The Relationship ◽  
Age Related Changes

Background:The purpose of the present investigation was to examine the relationship between age and the intensity of the daily physical activity in men and women, aged 18 to 69 years.Methods:A total 507 volunteers continuously wore a pedometer with a uni-ax-ial accelerometer (Lifecorder, Kenz, Japan) for 7 days, to determine the number of steps (steps/day) as well as the time spent in physical activity (minutes/day) at light (below 3 METs), moderate (3 to 6 METs), and vigorous (above 6 METs) intensities, respectively. All procedures carried out in the present investigation were conducted from 1999 to 2000 in Japan.Results:The time spent in moderate to vigorous intensity physical activity significantly decreased with aging (P < 0.01). In contrast, the middle- to older-aged individuals spent a longer time in light intensity physical activity in comparison with the younger individuals (P < 0.05). Furthermore, these age-associated differences of physical activity were also significant, even though the number of steps did not differ significantly.Conclusions:These results indicate that the intensity of daily physical activity decreases with increasing age regardless of the amount of daily physical activity.

scholarly journals Composition of time in movement behaviors and weight change in Latinx, Black and white participants

PLoS ONE ◽  
2021 ◽  
Vol 16 (1) ◽  
pp. e0244566
Author(s):  
Erika Rees-Punia ◽  
Mark A. Guinter ◽  
Susan M. Gapstur ◽  
Ying Wang ◽  
Alpa V. Patel
Keyword(s):  
Weight Change ◽  
White Women ◽  
Sedentary Time ◽  
Prevention Study ◽  
Black And White ◽  
Intensity Physical Activity ◽  
Vigorous Intensity ◽  
Race Ethnicity ◽  
The Relationship ◽  
Compositional Study

Background The relationship between time-use behaviors and prospective weight change is poorly understood. Methods A subset of Cancer Prevention Study-3 participants (n = 549, 58% women, 66% non-Latinx white) self-reported weight in 2015 and 2018 and completed an accelerometer protocol for seven days. Sedentary time, sleep, light, moderate, and vigorous intensity physical activity (PA) were treated as a compositional variable and multiple linear regression was used to examine associations between activity composition and weight change stratified by sex and race/ethnicity. Compositional isotemporal substitution analysis was used to quantify change in weight associated with reallocating 30 min./day. Results Activity composition was associated with weight change among women (p = 0.007), but not men (p = 0.356), and among Latinx (p = 0.032) and white participants (p = 0.001), but not Black participants (p = 0.903). Replacement of 30 min./day sedentary time with moderate-vigorous PA was associated with 3.49 lbs. loss (-6.76, -0.22) in Latinx participants and replacement with sleep was associated with 1.52 (0.25, 2.79) and 1.31 (0.40, 2.21) lbs. gain in white women and men. Conclusion The distribution of time spent in daily behaviors was associated with three-year weight change in women, Latinx, and white participants. This was the first longitudinal compositional study of weight change; thus, more studies are needed.

Light-Intensity Physical Activity Is Associated With Insulin Resistance in Elderly Japanese Women Independent of Moderate- to Vigorous-Intensity Physical Activity

2014 ◽  
Vol 11 (2) ◽  
pp. 266-271 ◽  
Author(s):  
Yuko Gando ◽  
Haruka Murakami ◽  
Ryoko Kawakami ◽  
Noriko Tanaka ◽  
Kiyoshi Sanada ◽  
...  
Keyword(s):  
Physical Activity ◽  
Insulin Resistance ◽  
Light Intensity ◽  
Triaxial Accelerometer ◽  
Light Physical Activity ◽  
Cross Sectional ◽  
Intensity Physical Activity ◽  
Elderly Japanese Women ◽  
Vigorous Intensity ◽  
Elderly Japanese

Background:It is unclear whether light physical activity is beneficially associated with insulin resistance, similar to moderate and/or vigorous physical activity. This cross-sectional study was performed to determine the relationship between the amount of light physical activity, as determined with a triaxial accelerometer, and insulin resistance.Methods:A total of 807 healthy men and women participated in this study. Physical activity was measured using a triaxial accelerometer worn for 28 days and summarized as light intensity (1.1–2.9 METs) or moderate to vigorous intensity (≥ 3.0 METs). Insulin resistance was evaluated by HOMA_R (FPG [mg/dL] × IRI [μU/mL]/405).Results:The daily time spent in light physical activity was inversely associated with HOMA_R (r = –0.173, P < 0.05). After adjustment for confounders, the association between light physical activity and HOMA_R remained statistically significant (β = –0.119, P < .05). Light physical activity remained significantly associated with HOMA_R following further adjustment for moderate to vigorous intensity activity (β = –0.125, P < .05). Similar results were observed when light physical activity was modeled as quartiles, especially in elderly women.Conclusions:These cross-sectional data suggest that light-intensity physical activity is beneficially associated with insulin resistance in elderly Japanese women.

scholarly journals Association Between Insulin-like Growth Factor 1 and Insulin Resistance in Obese Prepubertal Boys: A Cross-sectional Study

2020 ◽  
Author(s):  
Jiangying Kuang ◽  
Li Zhang ◽  
Yueqin Xu ◽  
Jiang Xue ◽  
Shuang Liang
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Cardiovascular Risk ◽  
Growth Factor ◽  
Cardiovascular Risk Factors ◽  
Whole Body ◽  
Sensitivity Index ◽  
Insulin Like Growth Factor ◽  
Prepubertal Boys ◽  
The Relationship

Abstract Background: As one of the most common features of obesity, insulin resistance is central to the pathogenesis of the metabolic syndrome. Low insulin-like growth factor 1(IGF-1) levels have been proven to be associated with many traditional cardiovascular risk factors, but it still remains controversy with the relationship between IGF-1 and insulin resistance. Accordingly, the main purpose of this study is to investigate the relationship between IGF-1 and insulin resistance in obese prepubertal boys.Methods: We used whole body insulin sensitivity index (WBISI) to represent insulin resistance. 70 obese prepubertal boys were included in this study, and the obese subjects were divided into two groups by using 1.285 as a threshold value for WBISI. Clinical examination and laboratory examinations were assessed for all participants.Results: Among obese boys, the group of children with WBISI ≤1.285 had lower IGF-1 standard deviation scores (SDS) (p = 0.021) than WBISI >1.285 group. The results of multivariate stepwise regression analysis show that WBISI was positively correlated with IGF-1 SDS (β =1.726, p = 0.002) after adjusting for traditional cardiovascular risk factors.Conclusion: IGF-1 SDS was negatively associated with insulin resistance in obese prepubertal boys, independent of other traditional cardiovascular disease risk markers.

scholarly journals Association between insulin-like growth factor 1 and insulin resistance in obese prepubertal boys:a cross-sectional study

2020 ◽  
Author(s):  
Jiangying Kuang ◽  
Li Zhang ◽  
Yueqin Xu ◽  
Jiang Xue ◽  
Shuang Liang
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Cardiovascular Risk ◽  
Growth Factor ◽  
Cardiovascular Risk Factors ◽  
Whole Body ◽  
Sensitivity Index ◽  
Insulin Like Growth Factor ◽  
Prepubertal Boys ◽  
The Relationship

Abstract Background As one of the most common features of obesity, insulin resistance is central to the pathogenesis of the metabolic syndrome. Low insulin-like growth factor 1(IGF-1) levels have been proven to be associated with many traditional cardiovascular risk factors, but it still remains controversy with the relationship between IGF-1 and insulin resistance. Accordingly, the main purpose of this study is to investigate the relationship between IGF-1 and insulin resistance in obese prepubertal boys.Methods We used whole body insulin sensitivity index (WBISI) to represent insulin resistance. 70 obese prepubertal boys were included in this study, and the obese subjects were divided into two groups by using 1.285 as a threshold value for WBISI. Clinical examination and laboratory examinations were assessed for all participants.Results Among obese boys, the group of children with WBISI ≤ 1.285 had lower IGF-1 standard deviation scores (SDS) (p = 0.021) than WBISI > 1.285 group. The results of multivariate stepwise regression analysis show that WBISI was positively correlated with IGF-1 SDS (β = 1.726, p = 0.002) after adjusting for traditional cardiovascular risk factors.Conclusion IGF-1 SDS was negatively associated with insulin resistance in obese prepubertal boys, independent of other traditional cardiovascular disease risk markers.

Relationship between insulin-like growth factor-1, insulin resistance and metabolic profile with pre-obesity and obesity in children

2021 ◽  
Vol 34 (3) ◽  
pp. 301-309 ◽  
Author(s):  
Marina Jaksic ◽  
Milica Martinovic ◽  
Najdana Gligorovic-Barhanovic ◽  
Tanja Antunovic ◽  
Mirjana Nedovic-Vukovic
Keyword(s):  
Insulin Resistance ◽  
Growth Factor ◽  
Nutritional Status ◽  
Metabolic Profile ◽  
Density Lipoprotein ◽  
Obese Group ◽  
Lipoprotein Cholesterol ◽  
Insulin Like Growth Factor ◽  
Total Body ◽  
The Relationship

Abstract Objectives Childhood obesity is a serious medical condition with alarmingly high rates worldwide. There is controversy regarding the relationship between insulin-like growth factor-1 (IGF-1) and pediatric obesity. We investigated the relationship between IGF-1, insulin resistance and metabolic profile with childhood pre-obesity/obesity. Methods The study involved 201 children aged 7–15 years, divided in three groups according to their nutritional status (International Obesity Task Force criteria): normal-weight (n=84), pre-obese (n=82), obese (n=35). Laboratory IGF-1, insulin, fasting blood glucose (FBG), lipid profile, alanine-aminotransferase (ALT), uric acid (UA), anthropometric and body composition parameters were analyzed. Body mass index and IGF-1 standard deviation score (SDS), waist-to-height ratio (WtHR) and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) score were calculated. Results Pre-obese/obese children had significantly higher IGF-1 SDS, FBG, insulin, HOMA-IR, UA, ALT, triglycerides, and lower high-density lipoprotein cholesterol (HDL-c); obese group had higher WtHR and low-density lipoprotein cholesterol (LDL-c) compared to controls (p<0.05). In obese group, IGF-1 SDS was positively correlated with fat free/muscle mass, total body water (p<0.05) and negatively correlated with LDL-c (p<0.05). In pre-obese/obese HOMA-IR and insulin were positively correlated with age, total body fat (TBF) (p<0.05) and negatively correlated with HDL-c (pre-obese) (p<0.05). Multivariate ordinal logistic regression analyses showed that IGF-1 SDS (OR=1.94; 95%CI: 1.21–3.11), TBF (OR=1.37; 95%CI: 1.21–1.54) were predictors of nutritional status (p<0.001). FBG (OR=42.39; 95%CI: 2.31–77.2) and UA (OR=1.03; 95%CI: 1.01–1.05) were predictors of IR (p<0.001). Conclusions IGF-1 SDS and TBF were predictors of nutritional status. Further studies are required to clarify the role of IGF-1 in pathophysiology of obesity and its comorbidities.

scholarly journals The Relationship Between Physical Activity and Executive Function Performance in Children With Attention-Deficit Hyperactivity Disorder

2010 ◽  
Vol 32 (6) ◽  
pp. 753-763 ◽  
Author(s):  
Jennifer Gapin ◽  
Jennifer L. Etnier
Keyword(s):  
Physical Activity ◽  
Attention Deficit Hyperactivity Disorder ◽  
Executive Function ◽  
Attention Deficit ◽  
Tower Of London ◽  
Hyperactivity Disorder ◽  
Intensity Physical Activity ◽  
Vigorous Intensity ◽  
Planning Task ◽  
The Relationship

Children with attention-deficit hyperactivity disorder (AD/HD) consistently perform worse on executive function (EF) tasks relative to those without AD/HD. Physical activity has a small effect on cognition in children and may be particularly beneficial for children with AD/HD by impacting fundamental EF deficiencies that characterize this disorder. The purpose of this study was to explore the extent to which physical activity is associated with EF in children with AD/HD. Eighteen boys (M age = 10.61, SD = 1.50) with AD/HD were recruited to complete four EF tasks. Physical activity was measured with an accelerometer that provided daily minutes of moderate-to-vigorous intensity physical activity; this measure was a significant predictor of performance on the Tower of London planning task, adjusted R2 = .28, F(1, 16) = 7.61, p < .05, and was positively associated with other EF measures. These results suggest that higher physical activity is associated with better EF performance in AD/HD children.

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