Primary cutaneous epithelioid mesenchymal neoplasm with ACTB‐GLI1 fusion: a case report

Author(s):  
Benjamin T. Rollins ◽  
David S. Cassarino ◽  
Matthew Lindberg
2021 ◽  
pp. 17-18
Author(s):  
Shaila Shaila ◽  
Aparna. C ◽  
Sowmiya. J ◽  
Geetha Sree. A

Solitary Fibrous Tumor (SFT) of prostate is an unusual mesenchymal neoplasm. We report SFT in a 62 year-old man which was clinically misdiagnosed as benign prostatic hyperplasia (BPH). The specimen of surgically resected two prostate mass, we received were solid grey-white nodular on cut surface. Based on histopathological ndings and IHC assessment, a diagnosis of SFT was made. In addition, we review the literature and discuss the challenging issues of misdiagnosis. The case is presented in view of its rarity.


2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Giovanni Centonze ◽  
Alessandro Mangogna ◽  
Tiziana Salviato ◽  
Beatrice Belmonte ◽  
Laura Cattaneo ◽  
...  

Gastroblastoma (GB) is a rare gastric epithelial-mesenchymal neoplasm, first described by Miettinen et al. So far, all reported cases described the tumor in children or young adults, and similarities with other childhood blastomas have been postulated. We report a case of GB in a 43-year-old patient with long follow up and no recurrence up to 100 months after surgery. So far, this is the second case of GB occurring in the adult age >40-year-old. Hence, GB should be considered in the differential diagnosis of microscopically comparable conditions in adults carrying a worse prognosis and different clinical approach.


2004 ◽  
Vol 122 (5) ◽  
pp. 220-222 ◽  
Author(s):  
Mohammad Mohammadianpanah ◽  
Simin Torabinejad ◽  
Mohammad Hadi Bagheri ◽  
Shapour Omidvari ◽  
Ahmad Mosalaei ◽  
...  

CONTEXT: Hemangiopericytoma is an uncommon mesenchymal neoplasm that rarely affects the spinal canal. Primary malignant hemangiopericytoma of the spinal column is extremely rare. CASE REPORT: We report on a case of primary epidural malignant hemangiopericytoma of the thoracic spinal column that invaded vertebral bone and caused spinal cord compression in a 21-year-old man. The patient presented with progressive back pain over a four-month period that progressed to paraparesis, bilateral leg paresthesia and urinary incontinence. The surgical intervention involved laminectomy and subtotal resection of the tumor, with posterior vertebral fixation. Postoperative involved-field radiotherapy was administered. A marked neurological improvement was subsequently observed. We describe the clinical, radiological, and histological features of this tumor and review the literature.


2008 ◽  
Vol 2 ◽  
pp. CMO.S627 ◽  
Author(s):  
M Mencoboni ◽  
M Bergaglio ◽  
M Truini ◽  
M Varaldo

The case presented here illustrates a 75 year old female patient who underwent surgical resection of a right adrenal mass of uncertain nature. The final histological diagnosis was consistent with leiomyosarcoma arising from the adrenal anatomic site. Primary leiomyosarcoma of the adrenal gland is a very rare malignant mesenchymal neoplasm: to our knowledge, this is only the twelfth case reported in literature. We describe the clinical course and a brief review of clinical and histological features, biologic behaviour, diagnostic approaches and therapeutic strategies.


2017 ◽  
Vol 10 (1) ◽  
pp. 58-62
Author(s):  
Tatyana M. Betova ◽  
Savelina L. Popovska ◽  
Radoslav G. Trifonov ◽  
Konstantina S. Karakadieva ◽  
Genoveva B. Valcheva ◽  
...  

SummaryDesmoid-type fibromatosis is a rare mesenchymal neoplasm with locally aggressive, infiltrating and destructive growth that is not characterized by a metastatic potential. According to their anatomical position, desmoid-type fibromatoses can be divided into three groups: extra-abdominal, intra-abdominal, and fibromatoses of the abdominal wall. Mesenteric fibromatoses account for 8% of the intra-abdominal ones. The latter are characterized by myofibroblastic proliferation and infiltration of both the pelvic and abdominal organs. We report a 26-year-old woman who complained of abdominal enlargement, feeling of heaviness, discomfort and reflux, which symptoms dated back 1-2 months prior to hospitalization. The patient underwent laparotomy due to subocclusive symptoms. Intraoperatively, a tumor sized 30 cm in diameter was found. The tumor originated from the mesentery and infiltrated in the jejunum, the entire ileum, and part of the caecum with perforation towards the abdominal cavity. The histological and immunohistochemical examinations are important for clarification of the diagnosis. The treatment requires a multidisciplinary approach, in which the surgical method has the key role.


2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Brian Cervenka ◽  
Brenda Villegas ◽  
Uttam Sinha

Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm that can present essentially anywhere in the body. Presentations in the hypopharynx are extremely rare with only two previous cases reported. We report the first case of postcricoid SFT occurring in a 58-year-old male requiring a microsuspension laryngoscopy excision following an unsuccessful transoral robotic attempt. The excision was uneventful, and the patient is currently without recurrence. Current management strategies of the hypopharyngeal SFT, the unique differential diagnosis, and challenges in surgical approaches in the postcricoid region are discussed.


2016 ◽  
Vol 88 (6) ◽  
Author(s):  
Mariusz Chabowski ◽  
Adam Paszkowski ◽  
Jerzy Skotarczak ◽  
Tadeusz Dorobisz ◽  
Michał Leśniak ◽  
...  

AbstractThe study presented a case of a patient with a glomus tumor of the stomach, a mesenchymal neoplasm manifesting with upper gastrointestinal bleeding (Forrest IB). The patient was operated twice. First, he underwent elective laparotomy, during which Billroth I (Rydygier’s method) gastric resection was performed. This his was followed by Billroth II resection with Braun’s anastomosis. Histopathological examination revealed glomus tumor tissue. Literature data on the glomus tumor of the stomach are presented.


2005 ◽  
Vol 114 (2) ◽  
pp. 87-89 ◽  
Author(s):  
Andrew P. Battiata ◽  
John Casler

Sclerosing epithelioid fibrosarcoma (SEF) is a rare variant of fibrosarcoma. It is a mesenchymal neoplasm composed of round to oval cells dispersed in a nestlike or cordlike distribution on a highly collagenous tissue background and is now recognized as a distinct clinical entity. In this report we discuss the presentation, diagnosis, and treatment of SEF. We focus on the unique histologic and immunohistochemical properties of this lesion. It is essential for both the surgeon and the pathologist to be aware of SEF and include it in the differential diagnosis for atypical head and neck neoplasms. Sclerosing epithelioid fibrosarcoma is a rare neoplasm that is now listed among the low-grade neoplasms that may occur in the head and neck. However, its behavior tends to be typical of more aggressive lesions. An awareness of this characteristic of SEF is essential for clinicians and pathologists alike.


Sarcoma ◽  
2010 ◽  
Vol 2010 ◽  
pp. 1-3 ◽  
Author(s):  
Rodney E. Wegner ◽  
Kevin M. McGrath ◽  
James D. Luketich ◽  
David M. Friedland

Extraosseous osteosarcoma (EOO) is a malignant mesenchymal neoplasm that is located in the soft tissues without direct attachment to the skeletal system and that produces osteoid, bone, or chondroid material. EOO is an extremely rare disease, accounting for only 1% of soft tissue sarcomas, and typically presents in either an extremity or the retroperitoneum. This paper presents the case of a 45-year-old Caucasian male with extraosseous osteosarcoma of the esophagus.


Author(s):  
Nupur Rastogi ◽  
R. K. Tanwar ◽  
B. Saxena

Undifferentiated embryonal sarcoma has been described in the liver, a rare malignant mesenchymal neoplasm, that occurs primarily in children and teenagers. Approximately 260 cases have been reported arising in the liver since 1978 when this disease was first described. Its pathogenesis is still obscure. Authors presented a case of extrahepatic undifferentiated embryonal sarcoma in a 9-year-old female presenting with upper abdominal dull pain. Ultrasound and CT Scan showed normal liver architecture, with liver pushed upwards due to compression by tumor arising in the retroperitoneum. To the best of our knowledge, this is first case of extrahepatic undifferentiated embryonal sarcoma diagnosed on cytomorphology and confirmed by histopathology and immunohistochemistry markers.


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