Could SARS‐CoV‐2 burst the use of Non‐Invasive and Minimally Invasive treatments in paediatric dentistry?

Abstract Background In zoology, species descriptions conventionally rely on invasive morphological techniques, frequently leading to damage of the specimens and thus only a partial understanding of their structural complexity. More recently, non-destructive imaging techniques have successfully been used to describe smaller fauna, but this approach has so far not been applied to identify or describe larger animal species. Here, we present a combination of entirely non-invasive as well as minimally invasive methods that permit taxonomic descriptions of large zoological specimens in a more comprehensive manner. Results Using the single available representative of an allegedly novel species of deep-sea cephalopod (Mollusca: Cephalopoda), digital photography, standardized external measurements, high-field magnetic resonance imaging, micro-computed tomography, and DNA barcoding were combined to gather all morphological and molecular characters relevant for a full species description. The results show that this specimen belongs to the cirrate octopod (Octopoda: Cirrata) genus Grimpoteuthis Robson, 1932. Based on the number of suckers, position of web nodules, cirrus length, presence of a radula, and various shell characters, the specimen is designated as the holotype of a new species of dumbo octopus, G. imperator sp. nov. The digital nature of the acquired data permits a seamless online deposition of raw as well as derived morphological and molecular datasets in publicly accessible repositories. Conclusions Using high-resolution, non-invasive imaging systems intended for the analysis of larger biological objects, all external as well as internal morphological character states relevant for the identification of a new megafaunal species were obtained. Potentially harmful effects on this unique deep-sea cephalopod specimen were avoided by scanning the fixed animal without admixture of a contrast agent. Additional support for the taxonomic placement of the new dumbo octopus species was obtained through DNA barcoding, further underlining the importance of combining morphological and molecular datasets for a holistic description of zoological specimens.

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European Thyroid Association and Cardiovascular and Interventional Radiological Society of Europe 2021 Clinical Practice Guideline for the Use of Minimally Invasive Treatments in Malignant Thyroid Lesions

European Thyroid Journal ◽

10.1159/000516469 ◽

2021 ◽

pp. 1-13

Author(s):

Giovanni Mauri ◽

Laszlo Hegedüs ◽

Steven Bandula ◽

Roberto Luigi Cazzato ◽

Agnieszka Czarniecka ◽

...

Keyword(s):

Minimally Invasive ◽

Neck Dissection ◽

Surgical Complications ◽

High Intensity Focused Ultrasound ◽

External Beam Radiation ◽

Cervical Lymph Nodes ◽

Beam Radiation ◽

Surgical Risk ◽

Radiological Society ◽

Minimally Invasive Treatments

The growing detection of papillary thyroid microcarcinomas (PTMCs) is paralleled by an increase in surgical procedures. Due to the frequent indolent nature, cost, and risk of surgery, active surveillance (AS) and ultrasound-guided minimally invasive treatments (MITs) are in suitable cases of incidental PTMC proposed as alternatives to thyroidectomy. Surgery and radioiodine are the established treatments for relapsing cervical differentiated thyroid carcinoma (DTC) metastases. But radioiodine refractoriness, risk of surgical complications, adverse influence on quality of life, or declining repeat surgery have led to AS and MIT being considered as alternatives for slow-growing DTC nodal metastases. Also, for distant radioiodine-refractory metastases not amenable to surgery, MIT is proposed as part of a multimodality therapeutic approach. The European Thyroid Association and the Cardiovascular and Interventional Radiological Society of Europe commissioned these guidelines for the appropriate use of MIT. Based on a systematic PubMed search, an evidence-based approach was applied, and both knowledge and practical experience of the panelists were incorporated to develop the manuscript and the specific recommendations. We recommend that when weighing between surgery, radioiodine, AS, or MIT for DTC, a multidisciplinary team including members with expertise in interventional radiology assess the demographic, clinical, histological, and imaging characteristics for appropriate selection of patients eligible for MIT. Consider TA in low-risk PTMC patients who are at surgical risk, have short life expectancy, relevant comorbidities, or are unwilling to undergo surgery or AS. As laser ablation, radiofrequency ablation, and microwave ablation are similarly safe and effective thermal ablation (TA) techniques, the choice should be based on the specific competences and resources of the centers. Use of ethanol ablation and high-intensity focused ultrasound is not recommended for PTMC treatment. Consider MIT as an alternative to surgical neck dissection in patients with radioiodine refractory cervical recurrences who are at surgical risk or decline further surgery. Factors that favor MIT are previous neck dissection, presence of surgical complications, small size metastases, and <4 involved latero-cervical lymph nodes. Consider TA among treatment options in patients with unresectable oligometastatic or oligoprogressive distant metastases to achieve local tumor control or pain palliation. Consider TA, in combination with bone consolidation and external beam radiation therapy, as a treatment option for painful bone metastases not amenable to other established treatments.

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Teaching Minimally Invasive Interventions in Paediatric Dentistry: A Cross-Sectional Survey of Dental Schools in Iran

BMC Oral Health ◽

10.1186/s12903-021-01735-5 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

S. Moradi ◽

S. Sabbagh ◽

L. Timms ◽

V. Ravaghi

Keyword(s):

Dental Caries ◽

Minimally Invasive ◽

Public Health Problem ◽

Paediatric Dentistry ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Fissure Sealant ◽

Resin Infiltration ◽

Dental Schools ◽

Hall Technique

Abstract Background Dental caries is a significant public health problem in Iran. Teaching minimally invasive interventions in paediatric dentistry may facilitate the provision of treatment for untreated dental caries in children. We evaluated the teaching of such interventions in both undergraduate dental curriculum and Paediatric Dentistry Specialty Training Programme (PDSTP) in Iran. Methods This was a cross-sectional questionnaire-based survey. Participants in this study were the directors of 40 undergraduate programmes and 15 PDSTPs in all Iranian dental schools (response rate = 100%). Descriptive statistics were reported. Results The most commonly taught methods were preventive fissure sealant and preventive resin restoration (PRR), which were taught ‘both didactically and clinically’ in all undergraduate dental programmes. The least commonly taught methods were silver diamine fluoride (SDF), the Hall technique and resin infiltration, which were taught ‘both didactically and clinically’ in less than 5% of dental schools. The same three methods were the least commonly approaches taught in PDSTP, further, they were less often perceived to be ‘essential’. Conclusions There was a notable variation in the teaching of the management of dental caries in Iran’s dental education. Some minimally invasive approaches including SDF, the Hall technique and resin infiltration are not being commonly taught in Iranian dental schools despite the evidence base for these techniques.

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Minimally invasive treatments for lower urinary tract symptoms in men with benign prostatic hyperplasia: a network meta‐analysis

Cochrane Database of Systematic Reviews ◽

10.1002/14651858.cd013656.pub2 ◽

2021 ◽

Author(s):

Juan Franco ◽

Jae Hung Jung ◽

Mari Imamura ◽

Michael Borofsky ◽

Muhammad Imran Omar ◽

...

Keyword(s):

Urinary Tract ◽

Benign Prostatic Hyperplasia ◽

Minimally Invasive ◽

Lower Urinary Tract Symptoms ◽

Lower Urinary Tract ◽

Meta Analysis ◽

Prostatic Hyperplasia ◽

Urinary Tract Symptoms ◽

Minimally Invasive Treatments ◽

Lower Urinary

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Comparison of minimally invasive and non-invasive systems in lengthening total femoral prostheses

The Bone & Joint Journal ◽

10.1302/0301-620x.100b12.bjj-2018-0135.r1 ◽

2018 ◽

Vol 100-B (12) ◽

pp. 1640-1646 ◽

Cited By ~ 2

Author(s):

M. R. Medellin ◽

T. Fujiwara ◽

R. Clark ◽

L. M. Jeys

Keyword(s):

Minimally Invasive ◽

Leg Length Discrepancy ◽

Implant Survival ◽

Leg Length ◽

Range Of Movement ◽

Musculoskeletal Tumor Society ◽

Non Invasive ◽

Length Discrepancy ◽

The Mean

AimsThe aim of this study was to describe, analyze, and compare the survival, functional outcome, and complications of minimally invasive (MI) and non-invasive (NI) lengthening total femoral prostheses.Patients and MethodsA total of 24 lengthening total femoral prostheses, 11 MI and 13 NI, were implanted between 1991 and 2016. The characteristics, complications, and functional results were recorded. There were ten female patients and ten male patients. Their mean age at the time of surgery was 11 years (2 to 41). The mean follow-up was 13.2 years (seven months to 29.25 years). A survival analysis was performed, and the failures were classified according to the Modified Henderson System.ResultsThe overall implant survival was 79% at five, ten, and 20 years for MI prostheses, and 84% at five years and 70% at ten years for NI prostheses. At the final follow-up, 13 prostheses did not require further surgery. The overall complication rate was 46%. The mean revision-free implant survival for MI and NI prostheses was 59 months and 49 months, respectively. There were no statistically significant differences in the overall implant survival, revision-free survival, or the distribution of complications between the two types of prosthesis. Infection rates were also comparable in the groups (9% vs 7%; p = 0.902). The rate of leg-length discrepancy was 54% in MI prostheses and 23% in NI prostheses. In those with a MI prosthesis, there was a smaller mean range of movement of the knee (0° to 62° vs 0° to 83°; p = 0.047), the flexion contracture took a longer mean time to resolve after lengthening (3.3 months vs 1.07 months; p < 0.001) and there was a lower mean Musculoskeletal Tumor Society (MSTS) score (24.7 vs 27; p = 0.295).ConclusionThe survival and complications of MI and NI lengthening total femoral prostheses are comparable. However, patients with NI prosthesis have more accurate correction of leg-length discrepancy, a better range of movement of the knee and an improved overall function.

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miRNAs and lncRNAs: Potential Non-Invasive Biomarkers for Endometriosis

Biomedicines ◽

10.3390/biomedicines9111662 ◽

2021 ◽

Vol 9 (11) ◽

pp. 1662

Author(s):

Ioana Maria Maier ◽

Adrian Cornel Maier

Keyword(s):

Clinical Trials ◽

Minimally Invasive ◽

Gold Standard ◽

Noncoding Rnas ◽

Long Noncoding Rnas ◽

Diagnostic Methods ◽

Non Invasive ◽

Invasive Method ◽

Minimally Invasive Methods ◽

Exploratory Laparoscopy

Many studies have tried to understand the mechanism of endometriosis and its manner of manifestation. However, the only method of diagnosis considered as the gold standard in endometriosis is an invasive method called exploratory laparoscopy. Hence, there is a need to identify non-invasive or minimally invasive methods to minimize patients’ suffering, thus increasing their addressability at the earliest possible staging of the disease, and to diagnose this condition as soon as possible. miRNAs (microRNAs) and lncRNAs (long-noncoding RNAs) are potential non-invasive diagnostic methods for endometriosis. Multiple clinical trials indicate that miRNA can be used as a non-invasive method in the diagnosis and differentiation of endometriosis stages.

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Invasive, minimally invasive and non-invasive hemodynamic monitoring in perioperative medicine

Journal of Anesthesia & Critical Care Open Access ◽

10.15406/jaccoa.2020.12.00423 ◽

2020 ◽

Vol 12 (1) ◽

pp. 7-19

Author(s):

Guerrero Gutiérrez Manuel Alberto ◽

Pérez Nieto Orlando Rubén ◽

Eder Iván Zamarrón López ◽

Jesús Salvador Sánchez Díaz ◽

Escarramán Martínez Diego ◽

...

Keyword(s):

Intensive Care ◽

Pulmonary Artery ◽

Minimally Invasive ◽

Hemodynamic Monitoring ◽

Perioperative Period ◽

Invasive Monitoring ◽

Less Invasive ◽

Non Invasive ◽

Fundamental Part ◽

Invasive Hemodynamic Monitoring

The hemodynamic monitoring is a fundamental part of the patient in the perioperative period, during the last decade the monitoring at the patient's bedside has grown at giant steps, from the emergency area, operating room, to the Intensive Care area. One of its most important advances is the decrease in the use of pulmonary artery catheter, which is being replaced by ultrasound and less invasive monitoring techniques, in this article we will review from the beginning of the monitoring to the most used less invasive monitors currently.

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Possibilities of minimally invasive treatments of hemorrhoidal disease

Ambulatory surgery hospital-replacing technologies ◽

10.21518/1995-1477-2018-3-4-77-82 ◽

2018 ◽

pp. 77-82 ◽

Cited By ~ 1

Author(s):

M. V. Abritsova

Keyword(s):

Surgical Treatment ◽

Minimally Invasive ◽

Postoperative Period ◽

Harmonic Scalpel ◽

Hemorrhoidal Disease ◽

Single Center ◽

Narcotic Analgesics ◽

Group I ◽

Minimally Invasive Treatments ◽

Observation Period

The article presents the results of surgical treatment of patients with stages III to IV hemorrhoids followed by an observation period of 45 days, which is designed to improve the results of surgical treatment of this category of patients. The surgical treatment methods included doppler-guided transanal hemorrhoiddearterialization with mucopexy (DDM) (Group I) and harmonic scalpel hemorrhoidectomy (HSH) (Group II). Operated patients underwent all necessary examinations according to the “per protocol” principle. Study Design: single-center controlled randomized prospective. The effectiveness of DDM was comparable to that of hemorrhoidectomy (HE), which made it possible to significantly reduce the duration of the operation (DDM 17.9 ± 6.1 min, GE 34.5 ± 10.1 min (p <0.01) ), reduce the level of pain in the postoperative period (DDM an average of 2.5 points, HE 4.8 points (p <0.01)), reduce the frequency of narcotic analgesics (DDM an average of 1.3 doses, HE an average of 6.1 doses (p <0.01)) and shorten the period of disability (DDM 14.4 ± 5.2 days, HE 30.3 ± 5.4 days (p <0.01)) patients with stages III to IV disease.

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