The role of oxidative stress on aging in Caenorhabditis elegans

2004 ◽  
Vol 4 (s1) ◽  
pp. S254-S255
Author(s):  
Naoaki Ishiii
Keyword(s):  
Oxidative Stress ◽  
Caenorhabditis Elegans

scholarly journals Role of Presenilin in Mitochondrial Oxidative Stress and Neurodegeneration in Caenorhabditis elegans

2018 ◽  
Author(s):  
Shaarika Sarasija ◽  
Kenneth R. Norman
Keyword(s):  
Oxidative Stress ◽  
Caenorhabditis Elegans ◽  
Global Health ◽  
Mitochondrial Function ◽  
Therapeutic Strategies ◽  
Calcium Dysregulation ◽  
Mitochondrial Oxidative Stress ◽  
Health Crisis ◽  
Genes Encoding

Neurodegenerative diseases like Alzheimer’s disease (AD) are poised to become a global health crisis, and therefore understanding the mechanisms underlying the pathogenesis is critical for the development of therapeutic strategies. Mutations in genes encoding presenilin occur in most familial Alzheimer’s disease but the role of PSEN in AD is not fully understood. In this review, the potential modes of pathogenesis of AD are discussed, focusing on calcium homeostasis and mitochondrial function. Moreover, research using Caenorhabditis elegans to explore the effects of calcium dysregulation due to presenilin mutations on mitochondrial function, oxidative stress and neurodegeneration is explored.

Protective role of citric acid against oxidative stress induced by heavy metals in Caenorhabditis elegans

2019 ◽  
Vol 26 (36) ◽  
pp. 36820-36831
Author(s):  
Shaojuan Song ◽  
Yan Han ◽  
Yun Zhang ◽  
Honglian Ma ◽  
Lei Zhang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Heavy Metals ◽  
Caenorhabditis Elegans ◽  
Citric Acid ◽  
Protective Role

scholarly journals Role of Presenilin in Mitochondrial Oxidative Stress and Neurodegeneration in Caenorhabditis elegans

Antioxidants ◽  
2018 ◽  
Vol 7 (9) ◽  
pp. 111 ◽  
Author(s):  
Shaarika Sarasija ◽  
Kenneth Norman
Keyword(s):  
Oxidative Stress ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Caenorhabditis Elegans ◽  
Mitochondrial Function ◽  
Calcium Dysregulation ◽  
Mitochondrial Oxidative Stress ◽  
Health Crisis ◽  
Genes Encoding

Neurodegenerative diseases like Alzheimer’s disease (AD) are poised to become a global health crisis, and therefore understanding the mechanisms underlying the pathogenesis is critical for the development of therapeutic strategies. Mutations in genes encoding presenilin (PSEN) occur in most familial Alzheimer’s disease but the role of PSEN in AD is not fully understood. In this review, the potential modes of pathogenesis of AD are discussed, focusing on calcium homeostasis and mitochondrial function. Moreover, research using Caenorhabditis elegans to explore the effects of calcium dysregulation due to presenilin mutations on mitochondrial function, oxidative stress and neurodegeneration is explored.

792: Role of Oxidative Stress in Tumorigenic Potential of Bladder Cancer Cells

2005 ◽  
Vol 173 (4S) ◽  
pp. 214-215 ◽  
Author(s):  
Daniel Cho ◽  
Xiao Fang Ha ◽  
J. Andre Melendez ◽  
Louis J. Giorgi ◽  
Badar M. Mian
Keyword(s):  
Oxidative Stress ◽  
Bladder Cancer ◽  
Cancer Cells ◽  
Tumorigenic Potential ◽  
Bladder Cancer Cells
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