Molecular and cellular mechanisms of cytotoxicity in animals

The monograph is devoted to the study of the heavy metal influence on molecular and cellular processes in the animal organism. The state of the art of molecular pathway response to heavy metal toxicity is highlighted. Aspects of the impact of aluminium, cadmium, lead, mercury, and copper on biochemical features of cells are outlined. The relationship between the presence of heavy metal in an organism and disturbances in molecular and cellular progressions is revealed. The scientific monograph is proposed to ecotoxicologists, ecologists, experts interested in molecular biomarkers and bioindication. The book may be useful for students and researchers.

Genetic factor affecting the milk production of mares

The article presents the results of studies to establish the influence of the record productivity of mothers’ mares on milk yield and the duration of productive life of mares-daughters of the Lithuanian heavy draft breed. It was found that the high level of milk productivity of mothers during the period of highest lactation (up to 4000 kg of milk) enabled their daughters to become leaders already during the first lactation. With an increase in the record milk yields per lactation in mothers, the heritability coefficient in mother-daughter pairs decreased and turned into negative values. The daughters of mares with record milk yields of up to 8000 are the most dairy among their contemporaries. The research results indicate that intensive milk production of mares during the first lactation can cause a reduction in the terms of their economic use due to the large loads on the developing fragile animal organism. The highest rates of productive life, number of lactations and life-long milk yield were obtained from daughters whose mothers had record milk yields per lactation from 7000 kg to 8000 kg of milk.

A Mini Review of the Effects of NSP and Exogenous Enzymes in Broiler Diets on Digestibility and Some Intestinal Functions

Summary NSP (non-starch polysaccharides) are a large group of compounds, which vary greatly in their chemical structure and properties. They are linked with the use of some of the alternative proteins or energy feed ingredients in broiler nutrition. Exogenous enzymes which act on NSP are sometimes in broiler production with the purpose of increasing digestibility of nutrients and consequently increasing broiler performance in production. This paper will attempt to review changes occurring in the digestive tract as a result of the use of feed with NSP soluble and insoluble in water, and the effect of NSPase on them, in terms of how an animal organism is burdened or helped to overcome the problems.

The method of alkaline loading and its application in the clinic of internal diseases

The works of recent years have clearly shown the importance that the alkaline-acid balance has in the physiology and pathology of the animal organism. The desire to maintain this balance at a certain height occurs by coordinating the work of a number of organs: the lungs, secreting C02, the liver, taking part in the production of ammonia, the gastrointestinal tract, secerning acid and alkaline secretions and, finally, the kidneys, giving urine with a high acid content and someone's slit, then with less-take part in the regulation of alkalineacid balance. That is why, naturally, the study of the functions of various organs aimed at regulating and maintaining the alkaline-acid balance attracted the attention of clinicians. Rehn and Gnzburg, then Pannewitz, Popescu, Inotesti. Su11a, and finally Rosenberg and Hellfors, studying fluctuations in the concentration of hydrogen ions in urine after loading with alkalis and acids, sought to gain an idea of kidney function aimed at maintaining the gap.- acids. balance, and at the same time apply this method to the study of the functional state of the kidneys in general. However, it turned out to be insufficient to talk about this condition on the basis of determining the Ph of urine. The Ph fluctuations are not always sufficiently prominent, as the review of the data obtained by the authors shows, because the concentration of hydrogen ions is a value depending on the ratio of acid to alkali (voltage 002 and bicarbonate content). This forced us to put forward another method for determining changes in the functions of tissues and kidneys for the introduction of alkali: Mainzer et al., A. G e f t e r emphasized the importance of the determination of bicarbonates in urine and suggested using the method of their determination by gasometric method (according to van Slyke'y), while giving this definition a much greater value than the study of Ph fluctuations alone.

Effect of yeast extract on mineral starvation

The question of the importance of the mineral constituents of the poverty reap and its ash in the nutrition of the animal organism was first raised by the well-known Comission de Ia gelatine. In the reports of this Commission, we find, among other things, the assumption that the cause of death of animals, when fed with boiled meat, or washed in distilled water and squeezed out fibrin, is the low ash content of the food.

Effect of Feeding the Thyroid Gland in Chickens

Despite the fact that the thyroid gland was described as early as the 17th century, its biological role for the animal organism is being clarified only by recent works.

Inovasi Kurikulum dalam Perspektif Komponen-Komponen Kurikulum Pendidikan Agama Islam

This study will elaborate on curriculum innovation in the perspective of PAI curriculum components. Where the curriculum can be interpreted as a variety of variations, there is a narrow view of the curriculum as a collection of subjects. As for the broad interpretations include all experiences gained by students because of the direction, guidance and responsibilities of the school. The conclusion is that a component is an integral and functional part that is inseparable from a curriculum system because the component itself has a role in the formation of the curriculum system. Because the curriculum can be likened to a human or animal organism, which has a certain anatomical arrangement. Thus, curriculum components are the parts or elements of the curriculum that have been planned to achieve certain educational goals. The curriculum can be likened to a human or animal organism, which has a certain anatomical arrangement. The main elements or components of the anatomy of the curriculum body are objectives, content or material, delivery processes or systems and media, and evaluation. These components are closely related to each other. Criticism of the writer which proposes the addition of religious values and the value of cooperation to maximize the Islamic Education curriculum in implementing it in schools.

ASSESSMENT OF THE INFLUENCE OF THE NEW STRESS CORRECTOR ON THE LABORATORY ANIMAL ORGANISM IN THE ACUTE EXPERIMENT

The article presents the results of acute toxicity of a new complex preparation in various ways of its introduction to laboratory white mice and rats. It was determined that a single intragastric and intramuscular administration of the maximum doses of the preparation does not cause a clinical picture of toxicosis and death of laboratory animals, on the basis of which the preparation is classified as hazardous class (GOST 12.1.007-76 “Harmful substances”) - low-hazard substances.