The relationship of heart rate and heart rate variability to non-diabetic fasting glucose levels and the metabolic syndrome: The Cardiovascular Health Study

2007 ◽  
Vol 24 (8) ◽  
pp. 855-863 ◽  
Author(s):  
P. K. Stein ◽  
J. I. Barzilay ◽  
P. P. Domitrovich ◽  
P. M. Chaves ◽  
J. S. Gottdiener ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Heart Rate ◽  
Cardiovascular Health ◽  
Fasting Glucose ◽  
Health Study ◽  
Cardiovascular Health Study ◽  
Glucose Levels ◽  
The Metabolic Syndrome ◽  
Relationship Of ◽  
The Relationship

scholarly journals Costs of the Metabolic Syndrome in Elderly Individuals: Findings from the Cardiovascular Health Study

Diabetes Care ◽  
2007 ◽  
Vol 30 (10) ◽  
pp. 2553-2558 ◽  
Author(s):  
L. H. Curtis ◽  
B. G. Hammill ◽  
M. A. Bethel ◽  
K. J. Anstrom ◽  
J. S. Gottdiener ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cardiovascular Health ◽  
Health Study ◽  
Cardiovascular Health Study ◽  
Elderly Individuals ◽  
The Metabolic Syndrome

scholarly journals The Relationship Between Metabolic Syndrome with Incidence of Stroke

2016 ◽  
Vol 4 (1) ◽  
pp. 25
Author(s):  
Fila Fatmisua Chrisna ◽  
Santi Martini
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Abdominal Obesity ◽  
Significant Relationship ◽  
Fasting Glucose ◽  
Hdl Cholesterol ◽  
Glucose Levels ◽  
The Third ◽  
The Metabolic Syndrome ◽  
The Relationship

Stroke is one of non-communicable diseases and affected by many risk factors. Some stroke risk factors have in common with the metabolic syndrome criteria, such as abdominal obesity, glucose intolerance, decreased HDL cholesterol, elevated triglyceride levels, and insulin resistance. The goals to analyze the relationship between the metabolic syndrome with the incidence of stroke. This research is analytic by using case-control design. The case groups were hospitalized patients of stroke and undergoing inpatient in dr. M. Soewandhie Surabaya. The case groups were 32 peoples and control group 32 peoples were selected at random. The variables studied were age, sex, metabolic syndrome, the first criteria, the second criteria of metabolic syndrome, and the third criteria of metabolic syndrome. The results showed that the majority of stroke patients in the age range 51-75 years (78%). Results of Chi-Square test indicates a significant relationship between the metabolic syndrome criteria first (abdominal obesity, triglycerides, and HDL cholesterol levels) p = 0,01 OR = 6,82 (95% CI = 1,23 to 68,17 ) and the second criteria of metabolic syndrome (HDL cholesterol, blood pressure, and fasting glucose levels) p= 0,007 OR = 5,80 (95% CI = 1,30 to 35,15) with the incidence of stroke. While for the third criteria of metabolic syndrome (fasting glucose levels, abdominal obesity, triglyceride  levels) there was no significant relationship to the incidence of stroke. It is expected for people, especially over the age of 35 years can do a lipid profile and circle abdominal measurements to detect of   metabolic syndrome and the risk of stroke.Keywords: Metabolic Syndrome, Stroke, Abdominal Obesity, Triglyceride, HDL

scholarly journals The Relationship Between Metabolic Syndrome with Incidence of Stroke

2016 ◽  
Vol 4 (1) ◽  
pp. 25
Author(s):  
Fila Fatmisua Chrisna ◽  
Santi Martini
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Abdominal Obesity ◽  
Significant Relationship ◽  
Fasting Glucose ◽  
Hdl Cholesterol ◽  
Glucose Levels ◽  
The Third ◽  
The Metabolic Syndrome ◽  
The Relationship

ABSTRACT Stroke is one of non-communicable diseases and affected by many risk factors. Some stroke risk factors have in common with the metabolic syndrome criteria, such as abdominal obesity, glucose intolerance, decreased HDL cholesterol, elevated triglyceride levels, and insulin resistance. The goals to analyze the relationship between the metabolic syndrome with the incidence of stroke. This research is analytic by using case-control design. The case groups were hospitalized patients of stroke and undergoing inpatient in dr. M. Soewandhie Surabaya. The case groups were 32 peoples and control group 32 peoples were selected at random. The variables studied were age, sex, metabolic syndrome, the first criteria, the second criteria of metabolic syndrome, and the third criteria of metabolic syndrome. The results showed that the majority of stroke patients in the age range 51-75 years (78%). Results of Chi-Square test indicates a significant relationship between the metabolic syndrome criteria first (abdominal obesity, triglycerides, and HDL cholesterol levels) p = 0,01 OR = 6,82 (95% CI = 1,23 to 68,17 ) and the second criteria of metabolic syndrome (HDL cholesterol, blood pressure, and fasting glucose levels) p= 0,007 OR = 5,80 (95% CI = 1,30 to 35,15) with the incidence of stroke. While for the third criteria of metabolic syndrome (fasting glucose levels, abdominal obesity, triglyceride  levels) there was no significant relationship to the incidence of stroke. It is expected for people, especially over the age of 35 years can do a lipid profile and circle abdominal measurements to detect of   metabolic syndrome and the risk of stroke. Keywords: Metabolic Syndrome, Stroke, Abdominal Obesity, Triglyceride, HDL

Abstract 16000: Impaired Fasting Glucose Increases Risk for an Unrecognized Myocardial Infarction: The Cardiovascular Health Study

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Richard B Stacey ◽  
Paul E Leaverton ◽  
Douglas D Schocken ◽  
Jennifer Peregoy ◽  
Mary Lyles ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Risk Factor ◽  
Impaired Fasting Glucose ◽  
Cardiovascular Health ◽  
Fasting Glucose ◽  
Medication Use ◽  
Health Study ◽  
Cardiovascular Health Study ◽  
Electrocardiogram Ecg ◽  
The Relationship

Background: Almost 25% of initial myocardial infarctions (MI) are unrecognized or clinically-silent (UMI). The prognostic implications of a UMI parallel those of symptomatic MIs. With diabetes mellitus (DM) being a known risk factor for UMI, further investigation is warranted regarding impaired fasting glucose (IFG) as a risk factor for UMI. Up to one-third of Americans have IFG . Therefore the relationship between UMI and IFG may have significant public health and clinical ramifications. Methods: The relationship between IFG and UMI was examined in the Cardiovascular Health Study: a cohort of individuals aged ≥ 65 years old. At year 2, there were 5,018 participants who had an initial 12-lead electrocardiogram (ECG). Of these participants, those with prior coronary heart disease (CHD), incident CHD, or a UMI on initial ECG were excluded. Our study population consisted of 1,714 participants without exclusions with measured fasting glucose (normal fasting glucose, NFG; n = 844), IFG (n=679), and DM (n=191) who underwent a baseline 12-lead electrocardiogram (ECG). Using Minnesota code, an UMI was identified by the presence of pathological Q waves or minor Q waves with ST-T abnormalities. Crude and adjusted hazard ratios (HRs) were calculated. Cox proportional hazard models were used to adjust for age, gender, body mass index, hypertension, anti-hypertensive medication use, total cholesterol, HDL cholesterol, lipid-lowering medication use, and cigarette use. Results: The sample was 36% male, 95% white, and had a mean age of 72.4 ± 5.6 years. Over a mean follow-up of 8.1 years, there were 94 UMIs identified among NFG subjects, 110 among IFG subjects, and 35 among DM subjects. Relative to NFG, the crude risk ratio estimates for UMI with IFG and DM were 1.53 (95% CI: 1.16-2.01) and 1.85 (1.24-2.70), respectively. With adjustment, the HR for UMI in IFG compared with NFG was 1.37 (95% CI: 1.03-1.83; p=0.032), and the HR for UMI in DM compared with NFG was 1.59 (95% CI: 1.24-2.70; p=0.035). Conclusion: Impaired fasting glucose increased the risk for a subsequent unrecognized myocardial infarction. Considering the enormous number of individuals at risk, these findings suggest the need for more aggressive CVD prevention activities.

scholarly journals OB2 THE COST OF THE METABOLIC SYNDROME IN THE ELDERLY: FINDINGS FROM THE CARDIOVASCULAR HEALTH STUDY

2007 ◽  
Vol 10 (3) ◽  
pp. A19
Author(s):  
LH Curtis ◽  
BG Hammill ◽  
MA Bethel ◽  
KJ Anstrom ◽  
JS Gottdiener ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Cardiovascular Health ◽  
The Elderly ◽  
Health Study ◽  
Cardiovascular Health Study ◽  
The Metabolic Syndrome ◽  
The Cost

scholarly journals Genetically Elevated Fetuin-A Levels, Fasting Glucose Levels, and Risk of Type 2 Diabetes: The Cardiovascular Health Study

Diabetes Care ◽  
2013 ◽  
Vol 36 (10) ◽  
pp. 3121-3127 ◽  
Author(s):  
M. K. Jensen ◽  
T. M. Bartz ◽  
L. Djousse ◽  
J. R. Kizer ◽  
S. J. Zieman ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cardiovascular Health ◽  
Fasting Glucose ◽  
Health Study ◽  
Cardiovascular Health Study ◽  
Fetuin A ◽  
Glucose Levels

scholarly journals Serum IGF1, metabolic syndrome, and incident cardiovascular disease in older people: a population-based study

2013 ◽  
Vol 168 (3) ◽  
pp. 393-401 ◽  
Author(s):  
Christa C van Bunderen ◽  
Mirjam M Oosterwerff ◽  
Natasja M van Schoor ◽  
Dorly J H Deeg ◽  
Paul Lips ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Older People ◽  
Population Based ◽  
Mortality Data ◽  
The Metabolic Syndrome ◽  
Longitudinal Aging Study Amsterdam ◽  
Aging Study ◽  
Definition Of ◽  
Relationship Of ◽  
The Relationship

ObjectiveHigh as well as low levels of IGF1 have been associated with cardiovascular diseases (CVD). The relationship of IGF1 with (components of) the metabolic syndrome could help to clarify this controversy. The aims of this study were: i) to investigate the association of IGF1 concentration with prevalent (components of) the metabolic syndrome; and ii) to examine the role of (components of) the metabolic syndrome in the relationship between IGF1 and incident CVD during 11 years of follow-up.MethodsData were used from the Longitudinal Aging Study Amsterdam, a cohort study in a representative sample of the Dutch older population (≥65 years). Data were available in 1258 subjects. Metabolic syndrome was determined using the definition of the US National Cholesterol Education Program Adult Treatment Panel III. CVD were ascertained by self-reports and mortality data.ResultsLevels of IGF1 in the fourth quintile were associated with prevalent metabolic syndrome compared with the lowest quintile (odds ratio: 1.59, 95% confidence interval (CI) 1.09–2.33). The middle up to the highest quintile of IGF1 was positively associated with high triglycerides in women. Metabolic syndrome was not a mediator in the U-shaped relationship of IGF1 with CVD. Both subjects without the metabolic syndrome and low IGF1 levels (hazard ratio (HR) 1.75, 95% CI 1.12–2.71) and subjects with the metabolic syndrome and high IGF1 levels (HR 2.28, 95% CI 1.21–4.28) demonstrated increased risks of CVD.ConclusionsIn older people, high-normal IGF1 levels are associated with prevalent metabolic syndrome and high triglycerides. Furthermore, this study suggests the presence of different pathomechanisms for both low and high IGF1 levels and incident CVD.

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