The continuums of impairment in vascular reactivity across the spectrum of cardiometabolic health: A systematic review and network meta‐analysis

2019 ◽  
Vol 20 (6) ◽  
pp. 906-920 ◽  
Author(s):  
Jordan Loader ◽  
Charles Khouri ◽  
Frances Taylor ◽  
Simon Stewart ◽  
Christian Lorenzen ◽  
...  
Keyword(s):  
Systematic Review ◽  
Vascular Reactivity ◽  
Meta Analysis ◽  
Cardiometabolic Health

scholarly journals Effectiveness of workplace wellness programmes for dietary habits, overweight, and cardiometabolic health: a systematic review and meta-analysis

2021 ◽  
Vol 6 (9) ◽  
pp. e648-e660
Author(s):  
José L Peñalvo ◽  
Diana Sagastume ◽  
Elly Mertens ◽  
Irina Uzhova ◽  
Jessica Smith ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dietary Habits ◽  
Meta Analysis ◽  
Cardiometabolic Health ◽  
Workplace Wellness

Sugar-sweetened beverage consumption, weight gain, and risk of type 2 diabetes and cardiovascular diseases in Asia: a systematic review

2021 ◽  
Author(s):  
Nithya Neelakantan ◽  
Su Hyun Park ◽  
Guo-Chong Chen ◽  
Rob M van Dam
Keyword(s):  
Systematic Review ◽  
Type 2 Diabetes ◽  
Weight Gain ◽  
Cardiovascular Diseases ◽  
Meta Analysis ◽  
Cardiometabolic Health ◽  
Sugar Sweetened Beverages ◽  
Sweetened Beverages ◽  
Asian Populations

Abstract Context The prevalence of type 2 diabetes mellitus (T2DM) and cardiovascular diseases (CVDs) is increasing in Asia and several countries are adopting preventive policies to reduce consumption of sugar-sweetened beverages (SSBs). However, evidence on the relation between SSB consumption and cardiometabolic health in Asian populations has not been summarized. Objective In this systematic review, the associations between consumption of SSBs and cardiometabolic outcomes, including obesity, T2DM, and CVD, are examined in Asian populations. Data sources The PubMed, Scopus, and Web of Science databases, and gray literature were searched up to October, 2020 to identify relevant articles. Data extraction Two investigators independently extracted data from included studies. Data analysis When sufficient studies were available, a random-effects meta-analysis was used to calculate the pooled estimates (expressed as risk ratio [RR] and 95% confidence interval [CI]). Heterogeneity was tested and quantified using the Cochrane Q test and I2 statistic, respectively. Results Of the 17 studies included, 8 provided results about measures of adiposity (3 on weight change, 4 on body mass index (BMI), 2 on percent body fat, and 1 on abdominal obesity), 6 reported results about T2DM, and 3 reported on different CVD outcomes. High SSB consumption was significantly associated with greater weight gain and with a higher risk of selected CVD outcomes as compared with low consumption. In the meta-analysis, high SSB consumption was associated with greater T2DM risk before (RR, 1.51; 95%CI, 1.15–1.98 for highest vs lowest category; I2 = 76%) and after (RR, 1.38; 95%CI, 1.09–1.73; I2 = 56%) adjustment for BMI. Conclusions These findings suggest that high SSB consumption is directly associated with weight gain, risk of T2DM, and, possibly, selected CVD outcomes in Asian populations. Public health strategies to reduce SSB consumption in Asian countries are warranted. Systematic Review Registration PROSPERO registration no. CRD42019129456.Keywords: adiposity. cardiovascular disease, Asia, sugar-sweetened beverages, type 2 diabetes.

scholarly journals Cocoa Flavanol Intake and Biomarkers for Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

2016 ◽  
Vol 146 (11) ◽  
pp. 2325-2333 ◽  
Author(s):  
Xiaochen Lin ◽  
Isabel Zhang ◽  
Alina Li ◽  
JoAnn E Manson ◽  
Howard D Sesso ◽  
...  
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Cardiometabolic Health ◽  
Controlled Trials ◽  
Randomized Controlled

Comparing effectiveness of fat burners and thermogenic supplements to diet and exercise for weight loss and cardiometabolic health: Systematic review and meta-analysis

2021 ◽  
pp. 026010602098236
Author(s):  
James E Clark ◽  
Sarah Welch
Keyword(s):  
Systematic Review ◽  
Weight Loss ◽  
Confidence Interval ◽  
Dietary Supplements ◽  
Body Mass ◽  
Effect Size ◽  
Meta Analysis ◽  
Cardiometabolic Health ◽  
Chi Square ◽  
Diet And Exercise

Background: Those who are overfat face an onslaught of advice for losing weight, including using dietary supplements that purport to have fat burning capabilities to achieve a reduced body mass, fat mass and improvement in cardiometabolic health in combination with exercise or diet and exercise regimens. Aim: To examine long-term effectiveness of supplements for both weight loss and improvements in cardiometabolic health for these individuals. Methods: A PRISMA methods of systematic review was conducted from August 2018 through January 2019 using Medline, PubChem, PubMed, EBOSCO CINHAL and SPORTDiscus, and Google Scholar yielding 23,441 returns of which 21 studies (duration greater than 8 weeks with participant populations of BMI greater than 24.9) were included for meta-analysis. Meta-analysis examined pooled effect size and 95% confidence interval for: body mass, fat mass, fat-free mass, total cholesterol, high-density lipoproteins, low-density lipoproteins, resting metabolic rate. Intra-study effect sizes were compared with previously reported results for diet or diet and exercise in a 2x2 chi-square analysis for the number of studies that induced effects greater than or less than the effect size. Results: There is a general trend to show effectiveness (effect size greater than 0.00) for obtaining beneficial changes from use of thermogenic dietary supplements, yet the 95% confidence interval for effect size crossed 0.00 (indicating no benefit). Chi-square comparison to exercise, or combination of diet and exercise, indicates that responses induced from weight-loss supplements were less effective than what is obtained from utilizing exercise, or diet and exercise, without additional weight-loss supplements. Conclusion: There appears to be limited benefit that may be derived from the inclusion of thermogenic dietary supplements to reduce body mass and improve cardiometabolic health for individuals who are overfat.

Role of whey protein in vascular function: a systematic review and meta-analysis of human intervention studies

2021 ◽  
pp. 1-34
Author(s):  
Fatemeh Hajizadeh-Sharafabad ◽  
Elham Sharifi Zahabi ◽  
Ali Tarighat-Esfanjani
Keyword(s):  
Systematic Review ◽  
Arterial Stiffness ◽  
Whey Protein ◽  
Vascular Function ◽  
English Language ◽  
Vascular Reactivity ◽  
Augmentation Index ◽  
Meta Analysis ◽  
Pooled Analysis ◽  
Effect Sizes

Abstract Whey protein (WP) has been heavily appreciated as a rich source of bioactive peptides, with potential benefits for cardiovascular health. This study constitutes a systematic review and meta-analysis summarizing the effects of WP consumption on vascular reactivity, arterial stiffness, and circulatory biomarkers of vascular function. We searched electronic databases, including PubMed, SCOPUS, and Web of science for relevant articles from inception to July 2020. Original clinical trials published in English-language journals that investigated the effects of WP on vascular function were eligible. A total of 720 records were identified in the initial search; from these, 16 were included in our systematic review and 13 in meta-analysis. The pooled analysis of 6 studies showed a significant increase in flow-mediated dilation (FMD) after WP consumption (WMD: 1.09%, 95% CI: 0.17, 2.01, P=0.01). Meta-analysis of available data didn’t show any significant reduction in arterial stiffness measures including augmentation index (effect sizes: 7, WMD: −0.29%, 95% CI: −1.58, 0.98, P=0.64) and pulse wave velocity (effect sizes: 4, WMD: −0.72 m/s, 95% CI: −1.47, 0.03, P=0.06). Moreover, the pooled analysis of 6 effect sizes showed no significant effects on plasma levels of nitric oxide following WP supplementation (WMD: 0.42 μmol/L, 95% CI: −0.52 to 1.36, P=0.38). The overall results provided evidence supporting a protective effect of WP on endothelial function measured by FMD, but not for arterial stiffness measures and circulatory biomarker of vascular function. Further research is required to substantiate the benefits of WP on vascular function.

Effects of pycnogenol on cardiometabolic health: A systematic review and meta-analysis of randomized controlled trials

2019 ◽  
Vol 150 ◽  
pp. 104472 ◽  
Author(s):  
Mahsa Malekahmadi ◽  
Omid Moradi Moghaddam ◽  
Safieh Firouzi ◽  
Reza Daryabeygi-Khotbehsara ◽  
Sheikh Mohammed Shariful Islam ◽  
...  
Keyword(s):  
Systematic Review ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Cardiometabolic Health ◽  
Controlled Trials ◽  
Randomized Controlled
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